Explain the heterogenous subunits of Rpb1 by answering these questions. What is the difference between IIo, IIa and IIb? Which enzymes convert IIa to IIo, IIo to IIa and IIa to IIb? Solution Rpb I is a subunit of DNA directed RNA polymerase II which is encoded by POLR2A GENE. IIa - stabilises TATA binding proteins (TBP ) and TAF binding ( TBP associated factors ) . This has one subunit. IIb - this GTF HAS 2 subunits. intermediate in the recruitment of RNA polymerase II. Influences selection of the start point of transcription. This protein would enter the pre initiation complex after TBP. This protein bridges the TATA bound TBP and polymerase. *There appears to be a mistype in IIo as none of the transcription factors are named as IIo, but yes there is a transcription factor as IId. Kindly leave in the comments if that is the same you want details about and feel free to ask any question..