5. Motrala and mootra virechaniya
When describing the herbs and their actions, the terms ‘mutrala’
and ‘Mutravirechaneeya’ seem to be similar, although there is a
minute difference in their understanding.
Mutrala dravyas are those that increase the quantity of the urine
and may not necessarily expel it.
However, Mutravirechaneeya dravyas are those, which irrespective
of the quantity of urine produced, cause easy expulsion.
6. Mootra mala is composed of jala and agneeya mahabootha
Both jala and agni mahabootha drugs are required
simultaneously for mootrapravarthi vardanam
Jalamahabootha increases quantity
Agneeya mahabootha increases raktha bhara in mootrothsika
(nephrons )
7. Mootravirajaniyam
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LuÉqÉç qÉÔ§ÉÌuÉåरजनीयं urÉZrÉrÉÉç||
“mootravirachaniya is explained by chakrapani along with the
poorisha virachaniya property chakrapani explains that drugs that
gives normal colour and dosasambanda of purisha or mootra is relived
is called virajaneeya drugs
According to pv sharma mootravirachinya is normalizing urine colour
8. Dosha dushtam mutram viranjayitva prakrtauv sthapayati tad
mutravirajaneeyam”
Dravyas, which reduce the dosha dushti and bring about
normal varna to mutra, are known as Mutravirajaneeya dravya
9. Predominancy of agnibootha causes increase in pitha
and cause colouration
Mootravirajaneeya drugs should be seetha veerya
mainly
10. In some conditions like Agnimandya and Amajeerna, the
pachana of Ahara and subsequent Sara kitta vibhajana do not
take place properly leading to improper formation of urine or
discolored urine.
In conditions like Kamala, Pandu, Haridra meha, Manjishta
meha, and so on, srotavarodha and dosha dushti leads to
discolored urine
11. Diuretics
Mootravirechana drugs can be broadly correlated to diuretic drugs
Diuretics are medicines that help reduce the amount of water in the bod
y
Diuretics are used to treat the buildup of excess fluid in the body that oc
curs with some medical conditions such as congestive heart
failure, liver disease, and kidneydisease. Some diuretics are also prescribe
d to treat high bloodpressure. These drugs act on the kidneys to increas
e urine output. This reduces the amount of fluid in the bloodstream,whic
h in turn lowers blood pressure.
12. Classification of diuretics
Weak diuretics
Moderatly effecious diuretics
Very efficacious diuretics
Potassium sparing diuretics
13. Discolouration of urine
Discolored urine is often caused by medications, certain
foods or food dyes. In some cases, though, changes in urine
color may be caused by specific health problems.
The colour of urine may change from its normal colour in
many diseased condition related with kidney ,ureter etc
14. Abnormalities of urine colour
Orange brown – conjugated bilirubin ,concentrated urine caused by the
low fluid intake And drugs such as sulfasalazine
Redbrown colour – free hb in urine porphyrins ,beetroot, black berries
also drugs rifampicin ,Rifabutin ,clofazimine
Brown black colour – conjugated bilirubin ,drugs metronidazole chloro
quinine
Blue green – drugs dyes – prpofol ,fluresians
Haemeturia – glomerulo nephrites , kidney tumors ,hypertensive nephron
sclerosis
Interstial nephrites ,renal ischemia ,renal calculai with obstruction ,renal
stone etc .
38. Drug Rasa guna Veerya Vipaka
Datrbha Madura Snighda Seetha Madhura
Kusa Madhura kasaya Laghu Seetha Madhura
Gundra Madhura kasaya Guru Seetha Madhura
Itkata moola Madhura Guru snighda Seetha Madhura
39. DRUGS Action on
dosha
Action on
dhatu
Action
on mala
action on
agni
karmas
Vrikshadani KP samana vrshya Mootralam Deepana Mootravirec
hana
,mootraroga
haram
Swadamstra Tridoshahar
am
Vrshya Vasti vatha
nivarakam
Deepana Sophaharam
vasuka Kaphavatha
haram
Medo hara Mootralam Deepanam Bedanam
Vasira KV samana Medohara Durmeda
hara
pachana Medorogaha
ra
pasanabheda Kaphavatha
samana
Medohara Mootrakrich
ra haram
Pachana Bedana
,vasthivisho
danam
40. DRUGS Action on
dosha
Action on
dhatu
Action
on mala
action on
agni
karmas
Darbha Tridosha
shamaka
Rasyana Mootravir
echaniya
Mootravirechana
,dahaprasamanam
Kusha KP hara Rasayana Mootrala
m
Deepana Bastiroga hara ,
Pradaraharam
Kasa Kaphavat
ha haram
Medo hara Mootrala
m
Deepanam Gulma haaram
Gundra VP
samana
Sukla
sodhaka
Mootravir
echaniya
pachana Mootravirechaniya
,mootrasodhaka
Itkata Vatha
pithahara
Medohara Mootrakri
chra
haram
Pachana Mootravirechaneeya
,mootrakrichra haram
Mootraghathaharam
41. DRUGS Constituents Pharmacological activity
Vrikshadani The key bioactive constituents
in lorathes are coriaria lactone
comprised of sesquiterpene
lactones: coriamyrtin, tutin,
corianin, and coriatin
diuretic cytotoxic
antimicrobial
Swadamstra saponins, flavonoids, glycosides,
alkaloids, and tannins
diuretic anti diabetic activity
Vasuka saponins,steroids,alkaloids,flav
onoids, terpenes, benzoic acid
derivatives and cinnamic
acid derivatives
Anti inflammatory ,anti hyper
glycemic
Vaseera flavanoid , glycoside Antibacterial, anti
inflammatory
Pashanabheda Bergenin, Pashaanolactone,β-
Sitosterol, Stigmesterol, Tannic
Diuretic ,anti inflammatory
Anti diabetic activity
42. DRUGS Constituents Pharmacological activity
Darba The key bioactive constituents
are arundoin , cylindrin , fernenol ,
simiarenol , glutinone
diuretic,antihelminthic activity
Kusa Quinones, Terpenes, Alkaloids,
Saponins,
Tanins, Carbohydrates,Proteins,
Coumarins,
Phenolic compounds, Steroids
diuretic cns depressant
Kasa phytosterol, flavonoids, tannins
and saponin
Anti microbial diuretic
Gundra phenols, saponins and
flavonoids
Antibacterial, anti
inflammatory
Itkata phenols, saponins and
flavonoids
Diuretic ,anti inflammatory
Anti diabetic activity
44. Probable mode of action of drugs in
mootravirechaneeya
The mootra virechana drugs are madhura kashaya in rasa mainly
snighda guna Sheetha veerya and madhura vipaka ,which shows that the
jala mahabootha is dominant in these drugs
The jala mahabootha causes the increase Kapha and dravata in the
Shareera also kledathwa .to eliminate kledathwa more mootra will be
formed
The guru guna and snighda guna of some drugs in dasimani helps in
Anulomana
45. Probable mode of action by phyto
constituents
Certain active principles derived from the plants have been found to
cause diuresis. Carbohydrates and sugars in trinapanchamoola , due to
their osmotic activity these substances oppose the reabsorption of water
from the glomerular filtrate These substances produce more elimination
of water than sodium, and hence produce diuresis
Many plants from poeceae ,Liliaceae, Solanaceae, contain
spironolactone, which is a diuretic steroid
46. Drugs like Gokshura contain potassium alkali. Watery extract of Gokshura
possesses similar diuretic activity like urea
47. mootravirachaniya
Padma
Drug BN Family Parts used
Padma Nelumbo nucifera Nymphaeaceae Flower rizhome seed
Utpala Nelumbium SPECIES Nymphaeaceae Flower rhizhome seed
Nalina Nelumbo species Nymphaeaceae Flower rhizome seed
Kumuda (water lilly)white Nymphe alba Nymphaeaceae Flower rhzome seed
Saugandika (red water
)
Nymphae rubra Nymphaeaceae Flower rizhome seed
Pundarika (sveta kamala) Nelumbo dentata Nymphyaceae Flower rizhome seed
Satapatra synonym of
kamala
Nelumbo species nymphaeceae Flower rizhome seed
Madhuka Glycyrrhiza glabra fabacae Stem and root
Priyangu Callicarpa macrophylla Verbenacea Dried inflorescence
Dhataki pushpa Woodfordia floribunda Lytharacae Flower
56. Drug Rasa guna Veerya Vipaka
Padma Madura Snighda Seetha Madhura
Utpala Madhura Snighda Seetha Madhura
Nalinam Madhura kasaya Snighda Seetha Madhura
Kumuda Madhura Guru snighda Seetha Madhura
Soughandikam Madhura Guru rooksha Seetha Madhura
57. Drug Rasa guna Veerya Vipaka
Pundarika Madura Snighda Seetha Madhura
Madhuka Madhura Guru snighda Seetha Madhura
Priyamdgu Tikta kasaya Rooksha Seetha Katu
Dathaki puspha Katu kasaya Laghu Seetha Katu
58. DRUGS Action on
dosha
Action on
dhatu
Action on
mala
action on
agni
karmas
padma Pitha kapha
hara
Raktha
doshahara
Mootravirajani
ya ,vistanbhini
anulomanam Vishagna
raktha pitha
hara
Utpala same
properties as
padmaka
Nalina Same property
as of padmaka
Kumuda Same as
kamala
Sougandhika Same as
kamala
59. DRUGS Action on
dosha
Action on
dhatu
Action on
mala
action on
agni
karmas
pundarika
Best variety
compared to
padma
Pitha kapha
hara
Raksthadosh
ahara
Mootraviraja
niya
Vishagna
raktha pitha
hara
Satapatra same
properties as
padmaa
Madhuka Vatapitha
hara
Sonithastapa
nam ,
Mootra
virajaneeya
Anulomana Amasayavraa
ropana
,mootrakrichr
agnam
Priyanghu Vatapithahara Raktha
prasadana
Mootra
virajana
poorisha
sanghrahana
Deepana
Anulomana
Raktha pitha
hara
60. DRUGS Constituents Pharmacological activity
Padma five norsesqui terpenes, four
flavonoids, two triterpenes
and one alkaloid
antihyper cholestrimic.anti
ntioxidant activities,
Reducing oxidative
stress and the risk of chronic
diseases
Utpala Same as above
Nalina phytosterol, flavonoids,
tannins and saponin
Anti microbial diuretic
Kumuda phenols flavinoids nodyne, antiscrofulatic,
cardiotonic, demulcent and
sedative
Sougandhika phenols, and flavonoids Diuretic ,
61. DRUGS Constituents Pharmacological
activity
Pundarika Nymphaea dentate and
Nelumbo nucifera contain
the alkaloids nuciferine
and aporphine
Satapatra diuretic cns depressant
Madhuka -Pinene 3 β-Pinene
Octanol γ-Terpinene
Anti microbial anti
cancerous
Priyangu α-amyrenol, α-
amyrin, ursolic acid,
2α,3α,19α-trihydroxy -12-
dien-28- ursolic acid,
betulinic acid,
Anti diabetic anti bacterial
anti arthritic
Dataki pushpa phenols, and flavonoids Antiradical ,anti microbial
63. Mode of action of mootravirajaneeya
• Katu and Ushna cause samyak pachana and sroto shodhana
• Drugs like Padma, Utpala, Nalina and so forth, of
Mutravirajaneeya dashemani, being kashaya and sheeta, bring
about dushita Pitta to the normal condition, and hence, are
useful in the case of discolored urine
• Many plants mentioned in the Mutravirajaneeya gana of
Charaka have also found place in the Utpaladi gana of
Sushruta, hence, similar properties may be expected from the
Utpaladi gana dravyas also
67. Virechaniya Virachajaniya
Part where
drugs under
this gana
mainly acts .
Shakha koshta
Action on
dosha
P samana pitha samana
Action on dhatu upakledanam raktha
pithaharam
Action on mala mutrala Mootavrnaharam
69. Mootravaha srotas
• The channels (srotas) that carry mootra mala
• The mootravaha srotas remove kleda through urine
• Mootravaha srotho dusti Lakshana ,obstructed micturition
,abnormal urine formation,decreased urine formation ,painful
urination
• For mootravaha srotho dusti –mutrachricha chikitsa is to be
done acc to charaka
70. • The hetus of the mutrakrichra and mutraghata are
• 1)theekshna oushada
• 2)theekshna ahara
• Due to their lekhana property it destroys the dhatus and also
normal functioning of mootravaha srotas is affected
• So kleda in body get accumulated and finally mootraghata is
resulted
71. • Mootravirechana drugs with kashya tikta rasa ,sheeta veerya
,laghu snighda guna amd madhura katu vipaka
• Decreases pitha dosha with kasyaya tikta rasa and seetha
veerya
• Seetha veerya have mutrala action ,and kleda get eliminated
• Seetha veerya have dathu vardhaka and dahahara action also
so protects dhatus
• By prabhava mootrala action also add up to the mootra
virechana process
72. Application of mootravirechaniya in chikitsa
• It is useful in sopha related rogas
• Mootrakshayam –toxemia condition
• Jalodaram
• Plueral effusion
• Vastipresekam (increase in specific gravity)
• Asmari
• Sarkara
• Also prevention of asmari also generalized sopha
73. Applicationof mootravirajaneeya mahakasaya in
chikitsa
• Virajaneeya drugs can be used in treatment of
• Haridra meham
• Kalameham
• Manjistameham
• Here the seetha veerya makes pitha samana and decreases
varnavikara
74. Conclusion
• Mootra virechana drugs are mainly jaleeya bootha and agneya
bootha predominant
• Mootra virajaniya drugs are pitha hara drugs
• Mootra virechana drugs used in sopha asmari mootrakrichra
etc
• It acts on mootravaha samsthanam
• Mootravirajaniya drugs used to treat prameha like manjista
meha haridra meha etc
75. • Mootravirajaniya drugs acts on the rakthadathu
• Mutravirajaneeya dravyas are believed to impart normal color
to the urine. However, their action over urobilin, which is
responsible for imparting color according to modern
physiology is not clear, and further research in this field of
science is expected.
