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SUDDEN CARDIAC ARREST
AND DEATH
DR. SOUMEN PRASAD BEHERA
CONSULTANT CARDIOLOGIST
APOLLO HOSPITALS, BBSR
5 6 7 8
1 2 3 4
DEFINATION DATA ON SCD
CAUSES PATHOPHYSIOLOGY
ECG
PREDICTORS
MANAGEMENT PREVENTION
SUDDEN CARDIAC DEATH
RISK FACTORS
SUDDEN CARDIAC DEATH
•Natural death from cardiac causes
•Abrupt loss of consciousness within 1 hour of the onset of an
acute change in cardiovascular status
•Some definitions of SCD include up to a 24 hour period and
death during sleep
SUDDEN
CARDIAC DEATH
SUDDEN IRREVERSIBLE CESSATION OF ALL
BIOLOGIC FUNCTIONS
AS A CONSEQUENCE OF CARDIAC ARREST
CARDIAC ARREST
SUDDEN
CARDIAC DEATH
SUDDEN IRREVERSIBLE CESSATION OF ALL
BIOLOGIC FUNCTIONS
AS A CONSEQUENCE OF CARDIAC ARREST
CARDIAC ARREST
ABRUPT CESSATION OF
CARDIAC MECHANICAL FUNCTION
LEADING TO DEATH IN THE ABSENCE OF REVERSAL
BY A PROMPT INTERVENTION
DATA ON SCD
2 LAKHS/YEAR 3.8 LAKHS/YEAR 7 LAKHS/YEAR
IN HOSPITAL
SCA (US)
OUT OF
HOSPITAL SCD
(US)
SCD
INDIA
50 %
RULE
50% of all
cardiovascular deaths
50% of all SCDs are unexpected
first expressions of a cardiac
disorder
50% of years of
potential life lost due
to heart disease as it
affects the productive
years of one’s life
PERSONAL OR FAMILY HISTORY OF HEART DISEASE
04
03
02
01
SMOKING
HYPERCHOLESTEROLEMIA
RISK FACTORS FOR SUDDEN CARDIAC DEATH
HYPERTENSION
OBESITY
08
07
06
05
DIABETES
ALCOHOL CONSUMPTION
RISK FACTORS FOR SUDDEN CARDIAC DEATH
SEDENTARY LIFE STYLE
AGE : TWO PEAKS – 1ST YEAR OF LIFE & 45-75 YRS
12
11
10
09
GENDER :MALES > 2 TO 3 TIMES AS FEMALES
PSYCHOLOGICAL STRESS
RISK FACTORS FOR SUDDEN CARDIAC DEATH
DRUG ABUSE OF COCAINE AND AMPHETAMINES
14
13 VENTRICULAR ARRYTHYMMIAS (> 10 VPC/hr)
RISK FACTORS FOR SUDDEN CARDIAC DEATH
LOW LVEF IN CHRONIC IHD
A FIRST DEGREE RELATIVE
OF A SUDDEN CARDIAC DEATH VICTIM
PRIMARY CARDIAC ARREST
RISK FACTORS FOR SCD IN HCM
YOUNG AGE OF ONSET
STRONG FAMILY HISTORY OF SCD
SEPTAL THICKNESS > 30 mm
VENTRCULAR ARRYTHYMIAS
RISK FACTORS FOR SCD IN HCM
FALL IN BP DURING EXERCISE
SYNCOPE
NON SUSTAINED VT ON AMBULATORY ECG RECORDING
DEGREE OF CARDIAC FIBROSIS
ECG PREDICTORS OF SCD
1 2
4
3
PATHOLOGICAL Q WAVES
OR DYNAMIC ST/T CHANGES
PROLONGED QRS DURATION
OR QT INTERVAL OR LBBB
INCREASE R WAVE VOLTAGE
FRAGMENTED QRS
• Any Q-wave in leads V2–V3 ≥ 2 mm or QS complex in leads V2 and V3
• Q-wave ≥ 0.03 s and > 1 mm deep or QS complex in leads I, II, aVL, aVF, or
V4–V6 in any two leads of a contiguous lead grouping
• I, aVL,V6;
• V4–V6;
• II, III, and aVF
PATHOLOGICAL Q WAVE
PREDICTORS OF SCD
TMT
24 HOURS
HOLTER
EPISODES OF NON SUSUTAINED VENTRCULAR
TACHYCARDIA.
REDUCED HR VARIABILITY.
INCREASED VENTRCULAR
ECTOPICS.
CAUSES OF SCA
CAD 18%
NORMAL HEART 17%
VIRAL MYOCARDITIS 12%
ARRHYTHMOGENIC CARDIOMYOPATHY 10%
HCM 9%
MVP 8%
CONDUCTION SYSTEM
ABNORMALITIES 6%
ALCAPA 5%
AORTIC RUPTURE 3%
OTHERS 12%
SCD
IN ATHELETES
< 35 YRS : HCM
> 35 YRS : CAD
Ø DELTA WAVE
Ø SHORT PR INTERVAL
Ø DIRECTION OF ST AND T WAVE OPPOSITE TO THE DELTA WAVE
WPW SYNDROME
EARLY REPOLARISATION SYNDROME
•WIDESPREAD CONCAVE ST ELEVATION, MOST PROMINENT IN THE MID-TO-LEFT PRECORDIAL LEADS (V2-5)
•NOTCHING OR SLURRING AT THE J POINT
•NO RECIPROCAL ST DEPRESSION TO SUGGEST OCCLUSION MI
BRUGADA
SYNDROME
TYPE 1
COVED ST SEGMENT ELEVATION >2MM IN >1 OF V1-V3 FOLLOWED BY A NEGATIVE T WAVE.
IT IS OFTEN REFERRED TO AS BRUGADA SIGN
TYPE 2
>2 mm OF SADDLEBACK SHAPED ST ELEVATION.
TYPE 3
MORPHOLOGY OF EITHER TYPE 1 OR TYPE 2, BUT WITH <2MM OF ST SEGMENT ELEVATION
ARRHYTHMOGENIC RV CARDIOMYOPATHY
SUDDEN CARDIAC DEATH
FOUR TEMPORAL PERSPECTIVES
PATHOPHYSIOLOGY OF SCD
MANAGEMENT OF SCA
ASSESS THE RHYTHM
A
ASSESS THE RHYTHM
A
ASSESS RHYTHM
B
DC SHOCK AND CPR
B
PREVENTION
01 02 03 04
ANTI
ARRHYTHMIC
DRUGS
ICD
CATHETER
ABLATION
THERAPY
SURGICAL
INTERVENTIONAL
STRATEGY
SUDDEN CARDIAC DEATH@.pdf

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SUDDEN CARDIAC DEATH@.pdf

  • 1. SUDDEN CARDIAC ARREST AND DEATH DR. SOUMEN PRASAD BEHERA CONSULTANT CARDIOLOGIST APOLLO HOSPITALS, BBSR
  • 2. 5 6 7 8 1 2 3 4 DEFINATION DATA ON SCD CAUSES PATHOPHYSIOLOGY ECG PREDICTORS MANAGEMENT PREVENTION SUDDEN CARDIAC DEATH RISK FACTORS
  • 3. SUDDEN CARDIAC DEATH •Natural death from cardiac causes •Abrupt loss of consciousness within 1 hour of the onset of an acute change in cardiovascular status •Some definitions of SCD include up to a 24 hour period and death during sleep
  • 4. SUDDEN CARDIAC DEATH SUDDEN IRREVERSIBLE CESSATION OF ALL BIOLOGIC FUNCTIONS AS A CONSEQUENCE OF CARDIAC ARREST CARDIAC ARREST
  • 5. SUDDEN CARDIAC DEATH SUDDEN IRREVERSIBLE CESSATION OF ALL BIOLOGIC FUNCTIONS AS A CONSEQUENCE OF CARDIAC ARREST CARDIAC ARREST ABRUPT CESSATION OF CARDIAC MECHANICAL FUNCTION LEADING TO DEATH IN THE ABSENCE OF REVERSAL BY A PROMPT INTERVENTION
  • 7. 2 LAKHS/YEAR 3.8 LAKHS/YEAR 7 LAKHS/YEAR IN HOSPITAL SCA (US) OUT OF HOSPITAL SCD (US) SCD INDIA
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  • 9. 50 % RULE 50% of all cardiovascular deaths 50% of all SCDs are unexpected first expressions of a cardiac disorder 50% of years of potential life lost due to heart disease as it affects the productive years of one’s life
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  • 12. PERSONAL OR FAMILY HISTORY OF HEART DISEASE 04 03 02 01 SMOKING HYPERCHOLESTEROLEMIA RISK FACTORS FOR SUDDEN CARDIAC DEATH HYPERTENSION
  • 13. OBESITY 08 07 06 05 DIABETES ALCOHOL CONSUMPTION RISK FACTORS FOR SUDDEN CARDIAC DEATH SEDENTARY LIFE STYLE
  • 14. AGE : TWO PEAKS – 1ST YEAR OF LIFE & 45-75 YRS 12 11 10 09 GENDER :MALES > 2 TO 3 TIMES AS FEMALES PSYCHOLOGICAL STRESS RISK FACTORS FOR SUDDEN CARDIAC DEATH DRUG ABUSE OF COCAINE AND AMPHETAMINES
  • 15. 14 13 VENTRICULAR ARRYTHYMMIAS (> 10 VPC/hr) RISK FACTORS FOR SUDDEN CARDIAC DEATH LOW LVEF IN CHRONIC IHD
  • 16. A FIRST DEGREE RELATIVE OF A SUDDEN CARDIAC DEATH VICTIM PRIMARY CARDIAC ARREST
  • 17. RISK FACTORS FOR SCD IN HCM YOUNG AGE OF ONSET STRONG FAMILY HISTORY OF SCD SEPTAL THICKNESS > 30 mm VENTRCULAR ARRYTHYMIAS
  • 18. RISK FACTORS FOR SCD IN HCM FALL IN BP DURING EXERCISE SYNCOPE NON SUSTAINED VT ON AMBULATORY ECG RECORDING DEGREE OF CARDIAC FIBROSIS
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  • 20. ECG PREDICTORS OF SCD 1 2 4 3 PATHOLOGICAL Q WAVES OR DYNAMIC ST/T CHANGES PROLONGED QRS DURATION OR QT INTERVAL OR LBBB INCREASE R WAVE VOLTAGE FRAGMENTED QRS
  • 21. • Any Q-wave in leads V2–V3 ≥ 2 mm or QS complex in leads V2 and V3 • Q-wave ≥ 0.03 s and > 1 mm deep or QS complex in leads I, II, aVL, aVF, or V4–V6 in any two leads of a contiguous lead grouping • I, aVL,V6; • V4–V6; • II, III, and aVF PATHOLOGICAL Q WAVE
  • 22. PREDICTORS OF SCD TMT 24 HOURS HOLTER EPISODES OF NON SUSUTAINED VENTRCULAR TACHYCARDIA. REDUCED HR VARIABILITY. INCREASED VENTRCULAR ECTOPICS.
  • 24. CAD 18% NORMAL HEART 17% VIRAL MYOCARDITIS 12% ARRHYTHMOGENIC CARDIOMYOPATHY 10% HCM 9% MVP 8% CONDUCTION SYSTEM ABNORMALITIES 6% ALCAPA 5% AORTIC RUPTURE 3% OTHERS 12%
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  • 28. SCD IN ATHELETES < 35 YRS : HCM > 35 YRS : CAD
  • 29. Ø DELTA WAVE Ø SHORT PR INTERVAL Ø DIRECTION OF ST AND T WAVE OPPOSITE TO THE DELTA WAVE WPW SYNDROME
  • 30. EARLY REPOLARISATION SYNDROME •WIDESPREAD CONCAVE ST ELEVATION, MOST PROMINENT IN THE MID-TO-LEFT PRECORDIAL LEADS (V2-5) •NOTCHING OR SLURRING AT THE J POINT •NO RECIPROCAL ST DEPRESSION TO SUGGEST OCCLUSION MI
  • 32. TYPE 1 COVED ST SEGMENT ELEVATION >2MM IN >1 OF V1-V3 FOLLOWED BY A NEGATIVE T WAVE. IT IS OFTEN REFERRED TO AS BRUGADA SIGN
  • 33. TYPE 2 >2 mm OF SADDLEBACK SHAPED ST ELEVATION.
  • 34. TYPE 3 MORPHOLOGY OF EITHER TYPE 1 OR TYPE 2, BUT WITH <2MM OF ST SEGMENT ELEVATION
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  • 39. SUDDEN CARDIAC DEATH FOUR TEMPORAL PERSPECTIVES
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  • 48. DC SHOCK AND CPR B
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  • 52. 01 02 03 04 ANTI ARRHYTHMIC DRUGS ICD CATHETER ABLATION THERAPY SURGICAL INTERVENTIONAL STRATEGY