SlideShare a Scribd company logo
1 of 1
Download to read offline
You have a patient, Janet, that has screening for her son, Julian, to have a dominant rare genetic
disorder which occurs in 1/1000 individuals. The test is 50% accurate. The Julian tests negative.
Assuming the disorder is 100% penetrant, what is the likelihood that he will have symptoms of
the disorder in question? Use Bayes' theorem.
b. What if the incidence of the condition was instead 1/100 and detection is 75%?

More Related Content

More from amie1085

_______ es m�s probable que se subcontrate al mejor postor. Habili.pdf
_______ es m�s probable que se subcontrate al mejor postor. Habili.pdf_______ es m�s probable que se subcontrate al mejor postor. Habili.pdf
_______ es m�s probable que se subcontrate al mejor postor. Habili.pdfamie1085
 
[10pts] Show that i=0ni!ei=n!1uneu�du.pdf
[10pts] Show that i=0ni!ei=n!1uneu�du.pdf[10pts] Show that i=0ni!ei=n!1uneu�du.pdf
[10pts] Show that i=0ni!ei=n!1uneu�du.pdfamie1085
 
Zoom el desaf�o de escalar con COVID-19 en el horizonte Serie de .pdf
Zoom el desaf�o de escalar con COVID-19 en el horizonte Serie de .pdfZoom el desaf�o de escalar con COVID-19 en el horizonte Serie de .pdf
Zoom el desaf�o de escalar con COVID-19 en el horizonte Serie de .pdfamie1085
 
Zero trust is a security stance for networking based on not trusting.pdf
Zero trust is a security stance for networking based on not trusting.pdfZero trust is a security stance for networking based on not trusting.pdf
Zero trust is a security stance for networking based on not trusting.pdfamie1085
 
Zeynep, ABD�de mezuniyetini kutlamak ve bahar tatili i�in Meksika� ya .pdf
Zeynep, ABD�de mezuniyetini kutlamak ve bahar tatili i�in Meksika� ya .pdfZeynep, ABD�de mezuniyetini kutlamak ve bahar tatili i�in Meksika� ya .pdf
Zeynep, ABD�de mezuniyetini kutlamak ve bahar tatili i�in Meksika� ya .pdfamie1085
 
Zara es la cadena principal del minorista de ropa del Grupo Inditex,.pdf
Zara es la cadena principal del minorista de ropa del Grupo Inditex,.pdfZara es la cadena principal del minorista de ropa del Grupo Inditex,.pdf
Zara es la cadena principal del minorista de ropa del Grupo Inditex,.pdfamie1085
 
Z0.975=1.96 What does the 0.975 represent What does the 1.96 repr.pdf
Z0.975=1.96 What does the 0.975 represent What does the 1.96 repr.pdfZ0.975=1.96 What does the 0.975 represent What does the 1.96 repr.pdf
Z0.975=1.96 What does the 0.975 represent What does the 1.96 repr.pdfamie1085
 
y^=2.5+22x Using least-squares regression, the forecast for the number.pdf
y^=2.5+22x Using least-squares regression, the forecast for the number.pdfy^=2.5+22x Using least-squares regression, the forecast for the number.pdf
y^=2.5+22x Using least-squares regression, the forecast for the number.pdfamie1085
 
Your task is to implement an informed search algorithm that will cal.pdf
Your task is to implement an informed search algorithm that will cal.pdfYour task is to implement an informed search algorithm that will cal.pdf
Your task is to implement an informed search algorithm that will cal.pdfamie1085
 
You have been at an industry trade show in Toronto all week. At the .pdf
You have been at an industry trade show in Toronto all week. At the .pdfYou have been at an industry trade show in Toronto all week. At the .pdf
You have been at an industry trade show in Toronto all week. At the .pdfamie1085
 
Your assignment is to research and investigate the Watergate Break I.pdf
Your assignment is to research and investigate the Watergate Break I.pdfYour assignment is to research and investigate the Watergate Break I.pdf
Your assignment is to research and investigate the Watergate Break I.pdfamie1085
 
You work as the IT administrator for a small business and are respon.pdf
You work as the IT administrator for a small business and are respon.pdfYou work as the IT administrator for a small business and are respon.pdf
You work as the IT administrator for a small business and are respon.pdfamie1085
 
You have a dataset that consists of the following columns- client.pdf
You have a dataset that consists of the following columns- client.pdfYou have a dataset that consists of the following columns- client.pdf
You have a dataset that consists of the following columns- client.pdfamie1085
 
You were given this balance sheet for a bank. Assets. .pdf
You were given this balance sheet for a bank. Assets.             .pdfYou were given this balance sheet for a bank. Assets.             .pdf
You were given this balance sheet for a bank. Assets. .pdfamie1085
 
You paid $10 to be entered into a raffle for a prize of $1,000. If .pdf
You paid $10 to be entered into a raffle for a prize of $1,000.  If .pdfYou paid $10 to be entered into a raffle for a prize of $1,000.  If .pdf
You paid $10 to be entered into a raffle for a prize of $1,000. If .pdfamie1085
 
You identify a pin1ui mutant with a pin1 gene that cannot be induced.pdf
You identify a pin1ui mutant with a pin1 gene that cannot be induced.pdfYou identify a pin1ui mutant with a pin1 gene that cannot be induced.pdf
You identify a pin1ui mutant with a pin1 gene that cannot be induced.pdfamie1085
 
You immunize an H2k mouse with chicken ovalbumin (a protein against .pdf
You immunize an H2k mouse with chicken ovalbumin (a protein against .pdfYou immunize an H2k mouse with chicken ovalbumin (a protein against .pdf
You immunize an H2k mouse with chicken ovalbumin (a protein against .pdfamie1085
 

More from amie1085 (17)

_______ es m�s probable que se subcontrate al mejor postor. Habili.pdf
_______ es m�s probable que se subcontrate al mejor postor. Habili.pdf_______ es m�s probable que se subcontrate al mejor postor. Habili.pdf
_______ es m�s probable que se subcontrate al mejor postor. Habili.pdf
 
[10pts] Show that i=0ni!ei=n!1uneu�du.pdf
[10pts] Show that i=0ni!ei=n!1uneu�du.pdf[10pts] Show that i=0ni!ei=n!1uneu�du.pdf
[10pts] Show that i=0ni!ei=n!1uneu�du.pdf
 
Zoom el desaf�o de escalar con COVID-19 en el horizonte Serie de .pdf
Zoom el desaf�o de escalar con COVID-19 en el horizonte Serie de .pdfZoom el desaf�o de escalar con COVID-19 en el horizonte Serie de .pdf
Zoom el desaf�o de escalar con COVID-19 en el horizonte Serie de .pdf
 
Zero trust is a security stance for networking based on not trusting.pdf
Zero trust is a security stance for networking based on not trusting.pdfZero trust is a security stance for networking based on not trusting.pdf
Zero trust is a security stance for networking based on not trusting.pdf
 
Zeynep, ABD�de mezuniyetini kutlamak ve bahar tatili i�in Meksika� ya .pdf
Zeynep, ABD�de mezuniyetini kutlamak ve bahar tatili i�in Meksika� ya .pdfZeynep, ABD�de mezuniyetini kutlamak ve bahar tatili i�in Meksika� ya .pdf
Zeynep, ABD�de mezuniyetini kutlamak ve bahar tatili i�in Meksika� ya .pdf
 
Zara es la cadena principal del minorista de ropa del Grupo Inditex,.pdf
Zara es la cadena principal del minorista de ropa del Grupo Inditex,.pdfZara es la cadena principal del minorista de ropa del Grupo Inditex,.pdf
Zara es la cadena principal del minorista de ropa del Grupo Inditex,.pdf
 
Z0.975=1.96 What does the 0.975 represent What does the 1.96 repr.pdf
Z0.975=1.96 What does the 0.975 represent What does the 1.96 repr.pdfZ0.975=1.96 What does the 0.975 represent What does the 1.96 repr.pdf
Z0.975=1.96 What does the 0.975 represent What does the 1.96 repr.pdf
 
y^=2.5+22x Using least-squares regression, the forecast for the number.pdf
y^=2.5+22x Using least-squares regression, the forecast for the number.pdfy^=2.5+22x Using least-squares regression, the forecast for the number.pdf
y^=2.5+22x Using least-squares regression, the forecast for the number.pdf
 
Your task is to implement an informed search algorithm that will cal.pdf
Your task is to implement an informed search algorithm that will cal.pdfYour task is to implement an informed search algorithm that will cal.pdf
Your task is to implement an informed search algorithm that will cal.pdf
 
You have been at an industry trade show in Toronto all week. At the .pdf
You have been at an industry trade show in Toronto all week. At the .pdfYou have been at an industry trade show in Toronto all week. At the .pdf
You have been at an industry trade show in Toronto all week. At the .pdf
 
Your assignment is to research and investigate the Watergate Break I.pdf
Your assignment is to research and investigate the Watergate Break I.pdfYour assignment is to research and investigate the Watergate Break I.pdf
Your assignment is to research and investigate the Watergate Break I.pdf
 
You work as the IT administrator for a small business and are respon.pdf
You work as the IT administrator for a small business and are respon.pdfYou work as the IT administrator for a small business and are respon.pdf
You work as the IT administrator for a small business and are respon.pdf
 
You have a dataset that consists of the following columns- client.pdf
You have a dataset that consists of the following columns- client.pdfYou have a dataset that consists of the following columns- client.pdf
You have a dataset that consists of the following columns- client.pdf
 
You were given this balance sheet for a bank. Assets. .pdf
You were given this balance sheet for a bank. Assets.             .pdfYou were given this balance sheet for a bank. Assets.             .pdf
You were given this balance sheet for a bank. Assets. .pdf
 
You paid $10 to be entered into a raffle for a prize of $1,000. If .pdf
You paid $10 to be entered into a raffle for a prize of $1,000.  If .pdfYou paid $10 to be entered into a raffle for a prize of $1,000.  If .pdf
You paid $10 to be entered into a raffle for a prize of $1,000. If .pdf
 
You identify a pin1ui mutant with a pin1 gene that cannot be induced.pdf
You identify a pin1ui mutant with a pin1 gene that cannot be induced.pdfYou identify a pin1ui mutant with a pin1 gene that cannot be induced.pdf
You identify a pin1ui mutant with a pin1 gene that cannot be induced.pdf
 
You immunize an H2k mouse with chicken ovalbumin (a protein against .pdf
You immunize an H2k mouse with chicken ovalbumin (a protein against .pdfYou immunize an H2k mouse with chicken ovalbumin (a protein against .pdf
You immunize an H2k mouse with chicken ovalbumin (a protein against .pdf
 

Recently uploaded

Employee wellbeing at the workplace.pptx
Employee wellbeing at the workplace.pptxEmployee wellbeing at the workplace.pptx
Employee wellbeing at the workplace.pptxNirmalaLoungPoorunde1
 
Hybridoma Technology ( Production , Purification , and Application )
Hybridoma Technology  ( Production , Purification , and Application  ) Hybridoma Technology  ( Production , Purification , and Application  )
Hybridoma Technology ( Production , Purification , and Application ) Sakshi Ghasle
 
Blooming Together_ Growing a Community Garden Worksheet.docx
Blooming Together_ Growing a Community Garden Worksheet.docxBlooming Together_ Growing a Community Garden Worksheet.docx
Blooming Together_ Growing a Community Garden Worksheet.docxUnboundStockton
 
A Critique of the Proposed National Education Policy Reform
A Critique of the Proposed National Education Policy ReformA Critique of the Proposed National Education Policy Reform
A Critique of the Proposed National Education Policy ReformChameera Dedduwage
 
Incoming and Outgoing Shipments in 1 STEP Using Odoo 17
Incoming and Outgoing Shipments in 1 STEP Using Odoo 17Incoming and Outgoing Shipments in 1 STEP Using Odoo 17
Incoming and Outgoing Shipments in 1 STEP Using Odoo 17Celine George
 
Paris 2024 Olympic Geographies - an activity
Paris 2024 Olympic Geographies - an activityParis 2024 Olympic Geographies - an activity
Paris 2024 Olympic Geographies - an activityGeoBlogs
 
Software Engineering Methodologies (overview)
Software Engineering Methodologies (overview)Software Engineering Methodologies (overview)
Software Engineering Methodologies (overview)eniolaolutunde
 
The Most Excellent Way | 1 Corinthians 13
The Most Excellent Way | 1 Corinthians 13The Most Excellent Way | 1 Corinthians 13
The Most Excellent Way | 1 Corinthians 13Steve Thomason
 
How to Configure Email Server in Odoo 17
How to Configure Email Server in Odoo 17How to Configure Email Server in Odoo 17
How to Configure Email Server in Odoo 17Celine George
 
SOCIAL AND HISTORICAL CONTEXT - LFTVD.pptx
SOCIAL AND HISTORICAL CONTEXT - LFTVD.pptxSOCIAL AND HISTORICAL CONTEXT - LFTVD.pptx
SOCIAL AND HISTORICAL CONTEXT - LFTVD.pptxiammrhaywood
 
POINT- BIOCHEMISTRY SEM 2 ENZYMES UNIT 5.pptx
POINT- BIOCHEMISTRY SEM 2 ENZYMES UNIT 5.pptxPOINT- BIOCHEMISTRY SEM 2 ENZYMES UNIT 5.pptx
POINT- BIOCHEMISTRY SEM 2 ENZYMES UNIT 5.pptxSayali Powar
 
Mastering the Unannounced Regulatory Inspection
Mastering the Unannounced Regulatory InspectionMastering the Unannounced Regulatory Inspection
Mastering the Unannounced Regulatory InspectionSafetyChain Software
 
Introduction to AI in Higher Education_draft.pptx
Introduction to AI in Higher Education_draft.pptxIntroduction to AI in Higher Education_draft.pptx
Introduction to AI in Higher Education_draft.pptxpboyjonauth
 
Solving Puzzles Benefits Everyone (English).pptx
Solving Puzzles Benefits Everyone (English).pptxSolving Puzzles Benefits Everyone (English).pptx
Solving Puzzles Benefits Everyone (English).pptxOH TEIK BIN
 
Pharmacognosy Flower 3. Compositae 2023.pdf
Pharmacognosy Flower 3. Compositae 2023.pdfPharmacognosy Flower 3. Compositae 2023.pdf
Pharmacognosy Flower 3. Compositae 2023.pdfMahmoud M. Sallam
 
ECONOMIC CONTEXT - LONG FORM TV DRAMA - PPT
ECONOMIC CONTEXT - LONG FORM TV DRAMA - PPTECONOMIC CONTEXT - LONG FORM TV DRAMA - PPT
ECONOMIC CONTEXT - LONG FORM TV DRAMA - PPTiammrhaywood
 

Recently uploaded (20)

Employee wellbeing at the workplace.pptx
Employee wellbeing at the workplace.pptxEmployee wellbeing at the workplace.pptx
Employee wellbeing at the workplace.pptx
 
Hybridoma Technology ( Production , Purification , and Application )
Hybridoma Technology  ( Production , Purification , and Application  ) Hybridoma Technology  ( Production , Purification , and Application  )
Hybridoma Technology ( Production , Purification , and Application )
 
Staff of Color (SOC) Retention Efforts DDSD
Staff of Color (SOC) Retention Efforts DDSDStaff of Color (SOC) Retention Efforts DDSD
Staff of Color (SOC) Retention Efforts DDSD
 
TataKelola dan KamSiber Kecerdasan Buatan v022.pdf
TataKelola dan KamSiber Kecerdasan Buatan v022.pdfTataKelola dan KamSiber Kecerdasan Buatan v022.pdf
TataKelola dan KamSiber Kecerdasan Buatan v022.pdf
 
Blooming Together_ Growing a Community Garden Worksheet.docx
Blooming Together_ Growing a Community Garden Worksheet.docxBlooming Together_ Growing a Community Garden Worksheet.docx
Blooming Together_ Growing a Community Garden Worksheet.docx
 
A Critique of the Proposed National Education Policy Reform
A Critique of the Proposed National Education Policy ReformA Critique of the Proposed National Education Policy Reform
A Critique of the Proposed National Education Policy Reform
 
9953330565 Low Rate Call Girls In Rohini Delhi NCR
9953330565 Low Rate Call Girls In Rohini  Delhi NCR9953330565 Low Rate Call Girls In Rohini  Delhi NCR
9953330565 Low Rate Call Girls In Rohini Delhi NCR
 
Incoming and Outgoing Shipments in 1 STEP Using Odoo 17
Incoming and Outgoing Shipments in 1 STEP Using Odoo 17Incoming and Outgoing Shipments in 1 STEP Using Odoo 17
Incoming and Outgoing Shipments in 1 STEP Using Odoo 17
 
Paris 2024 Olympic Geographies - an activity
Paris 2024 Olympic Geographies - an activityParis 2024 Olympic Geographies - an activity
Paris 2024 Olympic Geographies - an activity
 
Software Engineering Methodologies (overview)
Software Engineering Methodologies (overview)Software Engineering Methodologies (overview)
Software Engineering Methodologies (overview)
 
The Most Excellent Way | 1 Corinthians 13
The Most Excellent Way | 1 Corinthians 13The Most Excellent Way | 1 Corinthians 13
The Most Excellent Way | 1 Corinthians 13
 
How to Configure Email Server in Odoo 17
How to Configure Email Server in Odoo 17How to Configure Email Server in Odoo 17
How to Configure Email Server in Odoo 17
 
SOCIAL AND HISTORICAL CONTEXT - LFTVD.pptx
SOCIAL AND HISTORICAL CONTEXT - LFTVD.pptxSOCIAL AND HISTORICAL CONTEXT - LFTVD.pptx
SOCIAL AND HISTORICAL CONTEXT - LFTVD.pptx
 
POINT- BIOCHEMISTRY SEM 2 ENZYMES UNIT 5.pptx
POINT- BIOCHEMISTRY SEM 2 ENZYMES UNIT 5.pptxPOINT- BIOCHEMISTRY SEM 2 ENZYMES UNIT 5.pptx
POINT- BIOCHEMISTRY SEM 2 ENZYMES UNIT 5.pptx
 
Model Call Girl in Tilak Nagar Delhi reach out to us at 🔝9953056974🔝
Model Call Girl in Tilak Nagar Delhi reach out to us at 🔝9953056974🔝Model Call Girl in Tilak Nagar Delhi reach out to us at 🔝9953056974🔝
Model Call Girl in Tilak Nagar Delhi reach out to us at 🔝9953056974🔝
 
Mastering the Unannounced Regulatory Inspection
Mastering the Unannounced Regulatory InspectionMastering the Unannounced Regulatory Inspection
Mastering the Unannounced Regulatory Inspection
 
Introduction to AI in Higher Education_draft.pptx
Introduction to AI in Higher Education_draft.pptxIntroduction to AI in Higher Education_draft.pptx
Introduction to AI in Higher Education_draft.pptx
 
Solving Puzzles Benefits Everyone (English).pptx
Solving Puzzles Benefits Everyone (English).pptxSolving Puzzles Benefits Everyone (English).pptx
Solving Puzzles Benefits Everyone (English).pptx
 
Pharmacognosy Flower 3. Compositae 2023.pdf
Pharmacognosy Flower 3. Compositae 2023.pdfPharmacognosy Flower 3. Compositae 2023.pdf
Pharmacognosy Flower 3. Compositae 2023.pdf
 
ECONOMIC CONTEXT - LONG FORM TV DRAMA - PPT
ECONOMIC CONTEXT - LONG FORM TV DRAMA - PPTECONOMIC CONTEXT - LONG FORM TV DRAMA - PPT
ECONOMIC CONTEXT - LONG FORM TV DRAMA - PPT
 

You have a patient, Janet, that has screening for her son, Julian, t.pdf

  • 1. You have a patient, Janet, that has screening for her son, Julian, to have a dominant rare genetic disorder which occurs in 1/1000 individuals. The test is 50% accurate. The Julian tests negative. Assuming the disorder is 100% penetrant, what is the likelihood that he will have symptoms of the disorder in question? Use Bayes' theorem. b. What if the incidence of the condition was instead 1/100 and detection is 75%?