W H A T I S A N U S A N D H A N Dr
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Anusandhan is a state of being connected to one's true self, which traditions identify as God as inspired by the Guru. This state has surpassed subjective prejudices and is associated solely with global welfare. It has no petty pursuits or mean considerations, and is an objective state that has a benevolent effect of facilitating freedom for the entire universe. Anusandhan can also be considered the state of ultimate freedom in the truest sense.
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The document discusses the overuse of vulgar dance in Indian TV channels which promotes cheap entertainment rather than culture. While dance can be enjoyed and promote stress relief, the constant bombardment of vulgar aspects on TV is counterproductive and prevents blossoming. There is interest globally in learning about Indian traditions like yoga, ayurveda, and holistic health instead of the cheapest and most vulgar dances often shown on TV. Regular spiritual practice like NAMASMARAN could help overcome obstacles to global well-being.
Diabetes And Giddiness Dr
Diabetes can cause neuropathy or disturbances to the nervous system, which can lead to bizarre symptoms like giddiness. Giddiness experienced by diabetics can vary from minor to frightening. The complications of diabetes and misinformation about them can further disturb those affected. Repeating a mantra or name of God (Namasmarn) and drinking water to induce vomiting may help alleviate symptoms of giddiness in some cases. Long term, vitamins B, C and herbal supplements like chyavanprash may strengthen the nervous system. While feeling helpless is common, focusing on God's name through Namasmarn may help deal with difficult mental states that arise.
D I V O R C E D R
Divorce is often an act of escapism and defeat, where the ego succeeds over the self. It provides an illusion of freedom but prevents spiritual liberation. While spouses can be criminal, most divorces result from exaggerating ego needs rather than focusing on inner aspirations. This confusion of ego and self actually neglects the true self. Regular spiritual practice of namasmaran can help overcome ego and clear doubts to avoid the curse of divorce.
S W I N E F L U H1 N1
1. The document provides protective measures to prevent the spread of H1N1 flu, including daily practices like chanting names of God, drinking water, consuming herbs, yoga, and maintaining personal hygiene.
2. It recommends consuming herbs like neem, tulsi, bel, chyavanprash, and drinks with turmeric, ginger and honey to boost immunity.
3. Additional tips include taking vitamins, washing hands frequently, avoiding crowds, and adding ginger, pepper and jaggery to tea.
W H A T I S W E L L B E I N G Dr
Physical health is indicated by attributes like strength, coordination, posture, and endurance. In aging populations, good memory, senses, sleep, mood, and skin are also indicators. However, the most important sign of wellbeing is being connected to one's true or cosmic self through a process called anusandhan. This state appears to have a benevolent, enlightening effect on the universe. Whether the practice of namasmaran can help achieve this mental state of objective wellbeing is for readers to experience.
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This document discusses the relationship between microcosmic and macrocosmic phenomena in the universe and how they relate to human existence and behavior. It argues that we perceive only a small fraction of what exists due to the limitations of our senses. This separation from the true nature of the universe causes unrest in humans, manifesting as struggles for things like existence, possessions, and control. The key to harmony is realizing our role in the greater cosmic orchestra and accurately emulating it, which can be achieved through practices like Namasmaran meditation.
Y O G A K A R M A A N D N A M A S M A R A N D R
Nishkama karma, or action without attachment to results, is a concept in the Bhagavad Gita. While it seems impossible to act without thinking of results, subtle actions like thinking and feelings cannot be defined by their physical causes and effects. As actions evolve, they become less crude and more cosmic in nature, with results that cannot be quantified. The highest form of action is namasmāran, or remembering God, as it merges subjectivity and objectivity such that ownership of actions and results ceases. Namasmāran is widely practiced in religions and can help emancipate oneself and others.
D I V O R C E D R
Divorce is often an act of escapism and defeat, where the ego succeeds over the self. It provides an illusion of freedom but prevents spiritual liberation. While spouses can be criminal, most divorces result from exaggerating ego needs rather than focusing on inner aspirations. This confusion of ego and self actually neglects the true self. Regular spiritual practice of namasmaran can help get rid of the curse of divorce by clarifying doubts and protecting against the defeating influence of ego over time.
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The document discusses the overuse of vulgar dance in Indian TV channels which promotes cheap entertainment rather than culture. While dance can be enjoyed and promote stress relief, the constant bombardment of vulgar aspects on TV is counterproductive and prevents blossoming. There is interest globally in learning about Indian traditions like yoga, ayurveda, and holistic health instead of the cheapest and most vulgar dances often shown on TV. Regular spiritual practice like NAMASMARAN could help overcome obstacles to global well-being.
Diabetes And Giddiness Dr
Diabetes can cause neuropathy or disturbances to the nervous system, which can lead to bizarre symptoms like giddiness. Giddiness experienced by diabetics can vary from minor to frightening. The complications of diabetes and misinformation about them can further disturb those affected. Repeating a mantra or name of God (Namasmarn) and drinking water to induce vomiting may help alleviate symptoms of giddiness in some cases. Long term, vitamins B, C and herbal supplements like chyavanprash may strengthen the nervous system. While feeling helpless is common, focusing on God's name through Namasmarn may help deal with difficult mental states that arise.
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Divorce is often an act of escapism and defeat, where the ego succeeds over the self. It provides an illusion of freedom but prevents spiritual liberation. While spouses can be criminal, most divorces result from exaggerating ego needs rather than focusing on inner aspirations. This confusion of ego and self actually neglects the true self. Regular spiritual practice of namasmaran can help overcome ego and clear doubts to avoid the curse of divorce.
S W I N E F L U H1 N1
1. The document provides protective measures to prevent the spread of H1N1 flu, including daily practices like chanting names of God, drinking water, consuming herbs, yoga, and maintaining personal hygiene.
2. It recommends consuming herbs like neem, tulsi, bel, chyavanprash, and drinks with turmeric, ginger and honey to boost immunity.
3. Additional tips include taking vitamins, washing hands frequently, avoiding crowds, and adding ginger, pepper and jaggery to tea.
W H A T I S W E L L B E I N G Dr
Physical health is indicated by attributes like strength, coordination, posture, and endurance. In aging populations, good memory, senses, sleep, mood, and skin are also indicators. However, the most important sign of wellbeing is being connected to one's true or cosmic self through a process called anusandhan. This state appears to have a benevolent, enlightening effect on the universe. Whether the practice of namasmaran can help achieve this mental state of objective wellbeing is for readers to experience.
D H A R M A A N D C O S M I C D Y N A M I C S D R
This document discusses the relationship between microcosmic and macrocosmic phenomena in the universe and how they relate to human existence and behavior. It argues that we perceive only a small fraction of what exists due to the limitations of our senses. This separation from the true nature of the universe causes unrest in humans, manifesting as struggles for things like existence, possessions, and control. The key to harmony is realizing our role in the greater cosmic orchestra and accurately emulating it, which can be achieved through practices like Namasmaran meditation.
Y O G A K A R M A A N D N A M A S M A R A N D R
Nishkama karma, or action without attachment to results, is a concept in the Bhagavad Gita. While it seems impossible to act without thinking of results, subtle actions like thinking and feelings cannot be defined by their physical causes and effects. As actions evolve, they become less crude and more cosmic in nature, with results that cannot be quantified. The highest form of action is namasmāran, or remembering God, as it merges subjectivity and objectivity such that ownership of actions and results ceases. Namasmāran is widely practiced in religions and can help emancipate oneself and others.
D I V O R C E D R
Divorce is often an act of escapism and defeat, where the ego succeeds over the self. It provides an illusion of freedom but prevents spiritual liberation. While spouses can be criminal, most divorces result from exaggerating ego needs rather than focusing on inner aspirations. This confusion of ego and self actually neglects the true self. Regular spiritual practice of namasmaran can help get rid of the curse of divorce by clarifying doubts and protecting against the defeating influence of ego over time.
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The document discusses the wide-ranging effects of stress on c) Stressors can act on the hypothalamus which
every aspect of individual life, from the mind and body to regulates appetite, thirst, body temperature etc. This
personal, family and social relationships. It outlines how can cause anorexia or overeating leading to weight
stress affects the nervous, endocrine, immune, digestive and fluctuations.
reproductive systems, leading to issues like anxiety, high
blood pressure, ulcers, and sexual dysfunction. The
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The author describes feeling suffocated by concepts of God that demanded unquestioning surrender and challenged individual freedom. However, through practicing Namasmaran - remembering divine names - the author realized there is no need to believe or disbelieve in God. Namasmaran can be practiced like bathing or brushing without faith or disbelief. It leads to objective changes in individuals and the universe becoming self-evident, removing prejudices about theists and atheists. The author invites the reader to verify if Namasmaran can narrow the gap between human ideals and practices.
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1) Namasmaran, or the remembrance of God's name, is proposed as a way to unite the spiritual and practical aspects of life and facilitate the expression of global goodwill in all activities.
2) It involves the silent or loud remembrance of God, gurus, or holy symbols through techniques like chanting with prayer beads. This helps to reconnect one's physiological self with their true spiritual self.
3) By remembering the true self through symbols, it allows individual consciousness from all activities to merge with cosmic consciousness, making it the ultimate or "yoga of all yogas." Regular practice is needed to realize its benefits.
F R E E D O M O F C O N S C I E N C E D R
Freedom of conscience is rarely discussed but is important for overcoming problems in human life. While political and economic freedoms have been gained in many places, people still experience turmoil due to intolerant attitudes and malignant interests. Laws, traditions, and media sometimes restrict our conscience. However, the global conscience can be freed through the practice of Namasmaran by billions of people. Namasmaran means remembering the name of God or a guru through practices like chanting or meditation. It allows us to reconnect with our true selves and achieve unity of individual and cosmic consciousness.
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1. The document discusses grading happiness using criteria like durability, number of people involved, and intensity to determine what activities truly make one happy.
2. It provides examples like Buddha's lasting happiness as an A grade and temporary escapist activities as a C grade.
3. The tips encourage becoming more objective over time in assessing what really leads to long-lasting happiness through experience rather than following rules blindly.
Diabetes And Giddiness Dr
Diabetes can cause neuropathy or disturbances to the nervous system, which can lead to bizarre symptoms like giddiness. Giddiness experienced by diabetics can vary from minor to frightening. The complications of diabetes and misinformation about them can further disturb those affected. Repeating a mantra or name of God (Namasmarn) and drinking water to induce vomiting may help alleviate symptoms of giddiness in some cases. Long term, vitamins B, C and herbal supplements like chyavanprash may strengthen the nervous system. While feeling helpless is common, focusing on God's name through Namasmarn may help deal with difficult mental states that arise.
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Bathing has profound physical, mental and spiritual benefits beyond simple cleaning. It directly influences all cells in the body through its effects on the nervous, endocrine, immune and metabolic systems. While the details are not fully understood, bathing improves physical health, energy levels, strength, purity, longevity, health, willpower and destroys bad dreams through stimulating various body systems. It also improves enlightened intelligence and shifts one's consciousness to a more accurate state. Reciting prayers before bathing further connects one to their culture and lineage, combating feelings of isolation. Diabetics may experience benefits from bathing thrice daily such as improved metabolism and diabetes management.
Head Massage Dr
Dr. Shriniwas Kashalikar discusses the benefits of head massage with coconut oil. He used to dislike oiling the head due to stickiness and stains, but now massages his head daily with coconut oil. The massage exercises his arms and reduces dryness in his palms. He can stroll or watch TV during the massage to save time. Afterward, a warm or cold bath provides a refreshing and rejuvenating experience. Based on his own positive experience, Dr. Kashalikar believes traditional massage techniques deserve respect in mainstream medicine worldwide.
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Holistic Education Dr
Holistic education aims to facilitate physical, emotional, intellectual, and spiritual growth through practices like namasmarnan in order to promote well-being at the individual, group, national, and global levels. A piecemeal approach that focuses on petty pursuits under the guise of development has led to overproduction, excessive marketing, energy waste, pollution, and conditions that fuel terrorism. The lack of holistic education emphasizing an integrated approach is responsible for hype around value systems that promote these issues.
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1. The document discusses holistic approaches to saving energy, including switching off electronics when not in use, using stairs instead of elevators, and walking instead of driving for short trips.
2. It also discusses the practice of "Namasmaran", which involves remembering the name of God, gurus, or other spiritual figures, as a way to reunify one's physiological and true spiritual selves.
3. Namasmaran is described as a meditation practice that leads to the highest state of consciousness and spiritual fulfillment for people of any religion or belief system.
His Experience With Diabetes Dr
The document summarizes Dr. Shriniwas Kashalikar's experience managing his diabetes through supportive therapies in addition to medications. His blood sugar levels were not improving with medications alone. Through the practice of "Namasmran", or remembering God, he was able to overcome fear and anxiety. This allowed him to make positive lifestyle changes like diet, exercise, and herbal remedies that helped lower his blood sugar levels significantly with reduced medications. While not a guarantee for all, his experience shows the potential benefits of mindfulness and holistic supportive therapies for managing diabetes.
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The document outlines practical steps to improve mainstream education with a holistic approach. It suggests starting daily programs of physical fitness, sports, psychomotor training, pranayama, prayer, poetry recitation, and personal interactions. It emphasizes examining students' skills and capacities rather than just their ability to reproduce information from books. A holistic education requires physical, intellectual, emotional, spiritual, and pragmatic training through trial and error while encouraging openness and global unity. Participation is needed from society, government, and media to support holistic education efforts worldwide.
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Holistic health requires a total stress management approach for well-being. Dr. Shriniwas Kashalikar emphasizes that stress management is essential for holistic health, which leads to global welfare and everyone's complete blossoming or "superliving." A holistic examination covering physical, psychological, social, occupational, and other factors is needed to properly assess sources of stress and recommend a total stress management program for improving wellness.
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This document discusses conceptual stress, which is a type of stress caused by intellectual chaos arising from physical, emotional, or other causes. In modern life, the rapid pace of change can shatter our conceptual frameworks as new issues emerge that we cannot understand, leaving us helpless and miserable - this constitutes conceptual stress. Morality, ethics, and traditions from the past are often proving inadequate or irrelevant. Conceptual stress involves defective perceptions, thoughts, emotions, and physical needs associated with abnormal brain activity. It is minimized in those with a self-centered lifestyle but maximized in those with global perspectives and concerns who seek solutions but find their views ineffective. Remembering one's true self through namasmaran is suggested as a way to gain
Doubts Dr
Doubts and hesitancy can prevent fanaticism and ego, but total conviction that one's actions will benefit oneself and others allows one to progress triumphantly. If lacking such conviction, one may become depressed or passive, blaming others rather than acting. Therefore, when thoughts and plans are objectively associated with remembrance of the divine, the only choice is to confidently move forward.
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Life manifests through cells, organs, systems and organisms in various ways such as movements, emotions, thoughts and theories. It manifests through both tender love and brutal rage, as well as maniacal plans and melancholic deeds. Neither are humans completely right or wrong, but simply exist as life continues to manifest through them. The question is how to merge with the root of life itself, with the idea of merging also arising from life. NAMASMARAN is proposed to solve the enigma of the root of ideas that has eluded generations, though its validity remains to be verified.
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Respiratory issues like asthma are the most sensitive issue that is affecting millions worldwide. It hampers the daily activities leaving the body tired and breathless.
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It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
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Superliving Dr. Shriniwas Kashalikar
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1) Namasmaran, or the remembrance of God's name, is proposed as a way to unite the spiritual and practical aspects of life and facilitate the expression of global goodwill in all activities.
2) It involves the silent or loud remembrance of God, gurus, or holy symbols through techniques like chanting with prayer beads. This helps to reconnect one's physiological self with their true spiritual self.
3) By remembering the true self through symbols, it allows individual consciousness from all activities to merge with cosmic consciousness, making it the ultimate or "yoga of all yogas." Regular practice is needed to realize its benefits.
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Freedom of conscience is rarely discussed but is important for overcoming problems in human life. While political and economic freedoms have been gained in many places, people still experience turmoil due to intolerant attitudes and malignant interests. Laws, traditions, and media sometimes restrict our conscience. However, the global conscience can be freed through the practice of Namasmaran by billions of people. Namasmaran means remembering the name of God or a guru through practices like chanting or meditation. It allows us to reconnect with our true selves and achieve unity of individual and cosmic consciousness.
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2. It provides examples like Buddha's lasting happiness as an A grade and temporary escapist activities as a C grade.
3. The tips encourage becoming more objective over time in assessing what really leads to long-lasting happiness through experience rather than following rules blindly.
Diabetes And Giddiness Dr
Diabetes can cause neuropathy or disturbances to the nervous system, which can lead to bizarre symptoms like giddiness. Giddiness experienced by diabetics can vary from minor to frightening. The complications of diabetes and misinformation about them can further disturb those affected. Repeating a mantra or name of God (Namasmarn) and drinking water to induce vomiting may help alleviate symptoms of giddiness in some cases. Long term, vitamins B, C and herbal supplements like chyavanprash may strengthen the nervous system. While feeling helpless is common, focusing on God's name through Namasmarn may help deal with difficult mental states that arise.
Holistic Education, Economy And Health Dr
The document discusses holistic education and its benefits for the economy, health, and reducing stress. It argues that mainstream education focuses too much on superficial goals and neglects students' spiritual and practical development. A more well-rounded education that includes a productive domain like vocational skills would empower students, make schools self-sufficient, and reduce stress, crime, unemployment and other social issues. It provides tips and warnings for implementing a productive domain component in schools, suggesting it constitute 25% of time and be implemented carefully with the aim of students' all-round development.
G R O W T H & S U P E R L I V I N G D R
Bathing has profound physical, mental and spiritual benefits beyond simple cleaning. It directly influences all cells in the body through its effects on the nervous, endocrine, immune and metabolic systems. While the details are not fully understood, bathing improves physical health, energy levels, strength, purity, longevity, health, willpower and destroys bad dreams through stimulating various body systems. It also improves enlightened intelligence and shifts one's consciousness to a more accurate state. Reciting prayers before bathing further connects one to their culture and lineage, combating feelings of isolation. Diabetics may experience benefits from bathing thrice daily such as improved metabolism and diabetes management.
Head Massage Dr
Dr. Shriniwas Kashalikar discusses the benefits of head massage with coconut oil. He used to dislike oiling the head due to stickiness and stains, but now massages his head daily with coconut oil. The massage exercises his arms and reduces dryness in his palms. He can stroll or watch TV during the massage to save time. Afterward, a warm or cold bath provides a refreshing and rejuvenating experience. Based on his own positive experience, Dr. Kashalikar believes traditional massage techniques deserve respect in mainstream medicine worldwide.
Helpless Dr
The document discusses whether humans are helplessly controlled by their hormones and neurotransmitters or if they can gain freedom from this influence. It questions if current laws and environments support emancipation from being controlled by bodily chemicals. The author suggests that it is worthwhile to review whether people are truly helpless prisoners of their body's hormones and neurotransmitters or if creating the right intellectual, political, and material conditions could help free people from this perceived helplessness.
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Holistic education aims to facilitate physical, emotional, intellectual, and spiritual growth through practices like namasmarnan in order to promote well-being at the individual, group, national, and global levels. A piecemeal approach that focuses on petty pursuits under the guise of development has led to overproduction, excessive marketing, energy waste, pollution, and conditions that fuel terrorism. The lack of holistic education emphasizing an integrated approach is responsible for hype around value systems that promote these issues.
Holistic Approach To Saving Energy Dr Shriiwas Kashalikar
1. The document discusses holistic approaches to saving energy, including switching off electronics when not in use, using stairs instead of elevators, and walking instead of driving for short trips.
2. It also discusses the practice of "Namasmaran", which involves remembering the name of God, gurus, or other spiritual figures, as a way to reunify one's physiological and true spiritual selves.
3. Namasmaran is described as a meditation practice that leads to the highest state of consciousness and spiritual fulfillment for people of any religion or belief system.
His Experience With Diabetes Dr
The document summarizes Dr. Shriniwas Kashalikar's experience managing his diabetes through supportive therapies in addition to medications. His blood sugar levels were not improving with medications alone. Through the practice of "Namasmran", or remembering God, he was able to overcome fear and anxiety. This allowed him to make positive lifestyle changes like diet, exercise, and herbal remedies that helped lower his blood sugar levels significantly with reduced medications. While not a guarantee for all, his experience shows the potential benefits of mindfulness and holistic supportive therapies for managing diabetes.
Holistic Education Practical Steps Dr
The document outlines practical steps to improve mainstream education with a holistic approach. It suggests starting daily programs of physical fitness, sports, psychomotor training, pranayama, prayer, poetry recitation, and personal interactions. It emphasizes examining students' skills and capacities rather than just their ability to reproduce information from books. A holistic education requires physical, intellectual, emotional, spiritual, and pragmatic training through trial and error while encouraging openness and global unity. Participation is needed from society, government, and media to support holistic education efforts worldwide.
Holistic Health Examination Dr Shriniwas Kashalikar
Holistic health requires a total stress management approach for well-being. Dr. Shriniwas Kashalikar emphasizes that stress management is essential for holistic health, which leads to global welfare and everyone's complete blossoming or "superliving." A holistic examination covering physical, psychological, social, occupational, and other factors is needed to properly assess sources of stress and recommend a total stress management program for improving wellness.
M E A N I N G O F C O N C E P T U A L S T R E S S D R
This document discusses conceptual stress, which is a type of stress caused by intellectual chaos arising from physical, emotional, or other causes. In modern life, the rapid pace of change can shatter our conceptual frameworks as new issues emerge that we cannot understand, leaving us helpless and miserable - this constitutes conceptual stress. Morality, ethics, and traditions from the past are often proving inadequate or irrelevant. Conceptual stress involves defective perceptions, thoughts, emotions, and physical needs associated with abnormal brain activity. It is minimized in those with a self-centered lifestyle but maximized in those with global perspectives and concerns who seek solutions but find their views ineffective. Remembering one's true self through namasmaran is suggested as a way to gain
Doubts Dr
Doubts and hesitancy can prevent fanaticism and ego, but total conviction that one's actions will benefit oneself and others allows one to progress triumphantly. If lacking such conviction, one may become depressed or passive, blaming others rather than acting. Therefore, when thoughts and plans are objectively associated with remembrance of the divine, the only choice is to confidently move forward.
Frankly Speaking Dr
Life manifests through cells, organs, systems and organisms in various ways such as movements, emotions, thoughts and theories. It manifests through both tender love and brutal rage, as well as maniacal plans and melancholic deeds. Neither are humans completely right or wrong, but simply exist as life continues to manifest through them. The question is how to merge with the root of life itself, with the idea of merging also arising from life. NAMASMARAN is proposed to solve the enigma of the root of ideas that has eluded generations, though its validity remains to be verified.
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Moreover, we will include insights users will need to consider when validating their PGx workflow for all possible star alleles and options you have for automating your PGx analysis for large number of samples. Please join us for a session dedicated to the application of star allele genotyping and subsequent PGx workflows in our VarSeq software.
Patellar Instability: Diagnosis Management
Pictorial and detailed description of patellar instability with sign and symptoms and how to diagnose , what investigations you should go with and how to approach with treatment options . I have presented this slide in my 2nd year junior residency in orthopedics at LLRM medical college Meerut and got good reviews for it
After getting it read you will definitely understand the topic.
Hemodialysis: Chapter 5, Dialyzers Overview - Dr.Gawad
- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
5 Effective Homeopathic Medicines for Irregular Periods
Discover the benefits of homeopathic medicine for irregular periods with our guide on 5 common remedies. Learn how these natural treatments can help regulate menstrual cycles and improve overall menstrual health.
Visit Us: https://drdeepikashomeopathy.com/service/irregular-periods-treatment/
Ageing, the Elderly, Gerontology and Public Health
Challenges associated with ageing from a public health perspective
Breast cancer: Post menopausal endocrine therapy
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
Full Handwritten notes of RA by Ayush Kumar M pharm - Al ameen college of pha...
Full Handwritten notes of RA by Ayush Kumar M pharm - Al ameen college of pha...ayushrajshrivastava7
Regulatory Affairs
Full hand written notes
M.pharm - 1st year .How to choose the best dermatologists in Indore.
The skin is the largest organ and its health plays a vital role among the other sense organs. The skin concerns like acne breakout, psoriasis, or anything similar along the lines, finding a qualified and experienced dermatologist becomes paramount.
Know the difference between Endodontics and Orthodontics.
Your smile is beautiful.
Let’s be honest. Maintaining that beautiful smile is not an easy task. It is more than brushing and flossing. Sometimes, you might encounter dental issues that need special dental care. These issues can range anywhere from misalignment of the jaw to pain in the root of teeth.
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
This quiz was conducted as a promotional event for the 2024 Annual Meet of Kerala Chapter of API.
More than 20 participants took part everyday !
Top Travel Vaccinations in Manchester
Travel vaccination in Manchester offers comprehensive immunization services for individuals planning international trips. Expert healthcare providers administer vaccines tailored to your destination, ensuring you stay protected against various diseases. Conveniently located clinics and flexible appointment options make it easy to get the necessary shots before your journey. Stay healthy and travel with confidence by getting vaccinated in Manchester. Visit us: www.nxhealthcare.co.uk
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdf
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga
GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort. Recently uploaded (20)
How to Control Your Asthma Tips by gokuldas hospital.
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Ageing, the Elderly, Gerontology and Public Health
Full Handwritten notes of RA by Ayush Kumar M pharm - Al ameen college of pha...
Full Handwritten notes of RA by Ayush Kumar M pharm - Al ameen college of pha...
Know the difference between Endodontics and Orthodontics.
Know the difference between Endodontics and Orthodontics.
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdf
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdf
Tele Optometry (kunj'sppt) / Basics of tele optometry.
Tele Optometry (kunj'sppt) / Basics of tele optometry.
W H A T I S A N U S A N D H A N Dr
- 2. Anusandhan is said to be a state of one’s being connected with true self. This true self is identified in the traditions with the name of God as inspired by the Guru. This is supposed to be state that has surpassed and transcended all the subjective prejudices. This is supposed to be a sate that is associated with the aim of and aspiration of global welfare only. This is said to be a state which has no
- 3. petty pursuits and no mean considerations. This state is supposed to be an objective state that has benevolent effect on the entire universe. Benevolent effect means the effect that facilitates the ANUSANDHAN! ANUSANDHAN can also be said to be THE state of ultimate FREEDOM in true sense. DR. SHRINIWAS KASHALIKAR