Deze presentatie geeft je meer informatie over wat gewrichten zijn, welke soorten er bestaan en wat hun functie is.
Geschikt voor de lessen biologie in het secundair onderwijs en voor iedereen die meer over onze gewrichten wil te weten komen.
Striated muscle contracts to move limbs and maintain posture. The contraction of skeletal muscles is an energy-requiring process. In order to perform the mechanical work of contraction, actin and myosin utilize the chemical energy of the molecule adenosine triphosphate (ATP).Muscle contraction results from a chain of events that begins with a nerve impulse traveling in the upper motor neuron from the cerebral cortex in the brain to the spinal cord.When the signal to contract is sent along a nerve to the muscle, the actin and myosin are activated. Myosin works as a motor, hydrolyzing adenosine triphosphate (ATP) to release energy in such a way that a myosin filament moves along an actin…
Excitation–Contraction Coupling
Excitation–contraction coupling is the link (transduction) between the action potential generated in the sarcolemma and the start of a muscle contraction.
Sliding Filament Model of Contraction
For a muscle cell to contract, the sarcomere must shorten. However, thick and thin filaments—the components of sarcomeres—do not shorten. Instead, they slide by one another, causing the sarcomere to shorten while the filaments remain the same length. The sliding filament theory of muscle contraction was developed to fit the differences observed in the named bands on the sarcomere at different degrees of muscle contraction and relaxation. The mechanism of contraction is the binding of myosin to actin, forming cross-bridges that generate filament movement
Muscle is one of the four primary tissue types of the body, and the body contains three types of muscle tissue: skeletal muscle, cardiac muscle, and smooth muscle.
Deze presentatie geeft je meer informatie over wat gewrichten zijn, welke soorten er bestaan en wat hun functie is.
Geschikt voor de lessen biologie in het secundair onderwijs en voor iedereen die meer over onze gewrichten wil te weten komen.
Striated muscle contracts to move limbs and maintain posture. The contraction of skeletal muscles is an energy-requiring process. In order to perform the mechanical work of contraction, actin and myosin utilize the chemical energy of the molecule adenosine triphosphate (ATP).Muscle contraction results from a chain of events that begins with a nerve impulse traveling in the upper motor neuron from the cerebral cortex in the brain to the spinal cord.When the signal to contract is sent along a nerve to the muscle, the actin and myosin are activated. Myosin works as a motor, hydrolyzing adenosine triphosphate (ATP) to release energy in such a way that a myosin filament moves along an actin…
Excitation–Contraction Coupling
Excitation–contraction coupling is the link (transduction) between the action potential generated in the sarcolemma and the start of a muscle contraction.
Sliding Filament Model of Contraction
For a muscle cell to contract, the sarcomere must shorten. However, thick and thin filaments—the components of sarcomeres—do not shorten. Instead, they slide by one another, causing the sarcomere to shorten while the filaments remain the same length. The sliding filament theory of muscle contraction was developed to fit the differences observed in the named bands on the sarcomere at different degrees of muscle contraction and relaxation. The mechanism of contraction is the binding of myosin to actin, forming cross-bridges that generate filament movement
Muscle is one of the four primary tissue types of the body, and the body contains three types of muscle tissue: skeletal muscle, cardiac muscle, and smooth muscle.
It includes the basic anatomy physiology of skeletal muscles, the thorough working of the muscles, at superficial level to molecular level, the energy input, smooth muscle-cardiac-skeletal muscles differences, smooth muscle anatomy physiology.
It includes the basic anatomy physiology of skeletal muscles, the thorough working of the muscles, at superficial level to molecular level, the energy input, smooth muscle-cardiac-skeletal muscles differences, smooth muscle anatomy physiology.
18. Contractie: de “sliding filament theory” 1. ATP gebonden: myosine lage energiestand 2. Hydrolyse ATP: myosine hoge energiestand
19. Contractie: de “sliding filament theory” 1. ATP gebonden: myosine lage energiestand 2. Hydrolyse ATP: myosine hoge energiestand 3. Myosine bindt aan actine
20. Contractie: de “sliding filament theory” 1. ATP gebonden: myosine lage energiestand 2. Hydrolyse ATP: myosine hoge energiestand 3. Myosine bindt aan actine 4a. ADP en P i loslaten: myosine lage energiestand ADP + P i 4b. Verplaatsing actine
21. Contractie: de “sliding filament theory” 1. ATP gebonden: myosine lage energiestand 2. Hydrolyse ATP: myosine hoge energiestand 3. Myosine bindt aan actine 4a. ADP en P i loslaten: myosine lage energiestand ADP + P i 4b. Verplaatsing actine 5. ATP gebonden: myosine laat los van actine
22. Ca 2+ -ionen, troponine en tropomyosine Actine Tropomyosine Troponine Ca 2+ Myosine-bindingsplaats
23. Signaaltransductie: de neuromusculaire junctie Axon T tubule T tubule SR SR Ca 2+ Ca 2+ Ca 2+ Ca 2+ Ca 2+ Ca 2+
25. Spiermetabolisme 1 ATP per CP Anaerobe glycolyse: 2 ATP per glucose ATP ADP CP Creatine ATP Glucose Glycolyse Pyruvaat Lactaat Bloed
26. Spiermetabolisme 1 ATP per CP Anaerobe glycolyse: 2 ATP per glucose Aerobe respiratie: 36 ATP per glucose ATP ADP CP Creatine ATP Glucose Glycolyse Pyruvaat Lactaat Bloed ATP Glucose Pyruvaat Vet-zuren Amino- zuren CO 2 O 2 H 2 O
33. Contractie glad spierweefsel (1) Ontspannen staat Dense bodies Actine Myosine Tijdens contractie kan myosine over grote afstand langs actine schuiven Myosine
34. Contractie glad spierweefsel (2) 1. Influx Ca 2+ van buiten cel (en uit SR) 2. Ca 2+ bindt aan calmoduline (CaM) 4. MLCK fosforyleert en activeert lichte ketens van myosine SR ECF 3. Inactief myosine light chain kinase (MLCK) wordt geactiveerd MLCK inactief MLCK actief 5. Myosine bindt aan actine en resulteert in spiercontractie contractie
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