Integrated Systems Research develops and tests combinations of technical, market, governance and policy options to improve agricultural livelihood systems. The research improves understanding of local contexts to enhance targeting of potential interventions and scale out successful systems. The focus is on total farm productivity, including closing yield gaps in the most relevant components for smallholders. Future directions include refining indicators, developing systems research methods, accelerating cross-CRP learning, engaging higher-level organizations to achieve impact at scale, and building systems research capacity.