This study examined the effects of different land uses on the ecological integrity of high-altitude streams in northern Ecuador. The researchers assessed various environmental variables, macroinvertebrate communities, and biotic indices at sites with different land uses including cattle grazing, trout production, urban settlements, and mining. They found streams near cattle grazing and mining had poorer ecological integrity, while reference sites and those near trout production had better integrity. Natural land cover, especially at the catchment scale, was strongly correlated with the streams' ecological integrity. The researchers also projected future ecological integrity under different land use scenarios.