DNA molecules are found in the cytoplasm of prokaryotes and nearly all DNA is located in the nucleus of eukaryotes. DNA polymerase is the main enzyme that links individual nucleotides into DNA molecules during replication as shown in the diagram.
DNA molecules are located in the cytoplasm in prokaryotes, while in eukaryotes nearly all DNA is found in the nucleus. DNA polymerase is the main enzyme that links individual nucleotides into DNA molecules during replication, as shown by the diagram.
The document discusses molecular genetics and mutations. It describes the central dogma of biology where DNA is transcribed into RNA which is then translated into protein. It explains the structure of DNA and RNA, and the three types of RNA involved in protein synthesis. The process of transcription and translation are defined. Mutations can be caused by environmental factors and result in changes to DNA sequence. Point mutations and frameshift mutations are described, and the potential effects of mutations on proteins and diseases are discussed.
DNA repair is essential to correct damage to DNA that occurs during replication or from environmental factors like radiation and chemicals. There are several mechanisms of repair, including photoreactivation, excision repair, recombination repair, SOS repair, and mismatch repair. Excision repair is a multi-step process where the damaged section of DNA is cut out and replaced with new DNA synthesized by DNA polymerase. Recombination repair uses a homologous, undamaged DNA strand as a template to fill gaps left by excision repair when damage is too extensive. SOS repair induces mutagenesis to allow replication past DNA damage at the cost of mutations.
The document summarizes the development of potent and selective inhibitors of ecto-5'-nucleotidase based on an anthraquinone scaffold. It discusses the function of ectonucleotidases in hydrolyzing extracellular nucleotides. It then describes the synthesis and optimization of anthraquinone derivatives as inhibitors of ecto-5'-nucleotidase through structure-activity relationships. The most potent compounds showed submicromolar inhibition selectively for ecto-5'-nucleotidase over other ectonucleotidases and P2 receptors, indicating potential for cancer treatment.
The SOS gene is involved in DNA repair in E. coli. It is activated in response to DNA damage and induces DNA repair and mutagenesis through the RecA and LexA proteins. RecA binds to single-stranded DNA and promotes self-cleavage of the LexA repressor, allowing expression of SOS genes involved in DNA repair pathways like nucleotide excision repair and error-prone repair. This response allows E. coli to repair its DNA but can also lead to increased mutagenesis.
This document provides a summary of a biology textbook chapter on DNA, genes, and genetic engineering. It discusses:
- The structure of DNA as a double helix made of nucleotides with complementary base pairing.
- Genes are segments of DNA that code for proteins. DNA is transcribed into mRNA which is translated by ribosomes into polypeptides.
- Genetic engineering techniques allow genes to be transferred between organisms using vectors like plasmids. The process of inserting the human insulin gene into bacteria to produce insulin is described.
DNA repair mechanisms are essential for maintaining genomic integrity. There are several pathways for repairing different types of DNA damage: mismatch repair fixes errors during DNA replication, base excision repair removes damaged bases, nucleotide excision repair replaces larger sections of damaged DNA, and double-strand break repair fixes breaks in both DNA strands. Defects in DNA repair genes can lead to increased cancer risks and genetic disorders like xeroderma pigmentosum and Fanconi anemia. Overall, DNA repair helps prevent mutations from being passed to new cells.
The molecular basis of inheritance class 12Anurag Verma
James Watson and Francis Crick discovered that DNA has a double helix structure in 1953. DNA contains the genetic instructions that are used to direct the development and function of living organisms. It was shown that DNA is the genetic material that is faithfully copied and passed from parents to offspring. The four bases in DNA are adenine, thymine, guanine, and cytosine, which bond together in DNA in a specific pairing between bases to form the double helix structure.
DNA molecules are located in the cytoplasm in prokaryotes, while in eukaryotes nearly all DNA is found in the nucleus. DNA polymerase is the main enzyme that links individual nucleotides into DNA molecules during replication, as shown by the diagram.
The document discusses molecular genetics and mutations. It describes the central dogma of biology where DNA is transcribed into RNA which is then translated into protein. It explains the structure of DNA and RNA, and the three types of RNA involved in protein synthesis. The process of transcription and translation are defined. Mutations can be caused by environmental factors and result in changes to DNA sequence. Point mutations and frameshift mutations are described, and the potential effects of mutations on proteins and diseases are discussed.
DNA repair is essential to correct damage to DNA that occurs during replication or from environmental factors like radiation and chemicals. There are several mechanisms of repair, including photoreactivation, excision repair, recombination repair, SOS repair, and mismatch repair. Excision repair is a multi-step process where the damaged section of DNA is cut out and replaced with new DNA synthesized by DNA polymerase. Recombination repair uses a homologous, undamaged DNA strand as a template to fill gaps left by excision repair when damage is too extensive. SOS repair induces mutagenesis to allow replication past DNA damage at the cost of mutations.
The document summarizes the development of potent and selective inhibitors of ecto-5'-nucleotidase based on an anthraquinone scaffold. It discusses the function of ectonucleotidases in hydrolyzing extracellular nucleotides. It then describes the synthesis and optimization of anthraquinone derivatives as inhibitors of ecto-5'-nucleotidase through structure-activity relationships. The most potent compounds showed submicromolar inhibition selectively for ecto-5'-nucleotidase over other ectonucleotidases and P2 receptors, indicating potential for cancer treatment.
The SOS gene is involved in DNA repair in E. coli. It is activated in response to DNA damage and induces DNA repair and mutagenesis through the RecA and LexA proteins. RecA binds to single-stranded DNA and promotes self-cleavage of the LexA repressor, allowing expression of SOS genes involved in DNA repair pathways like nucleotide excision repair and error-prone repair. This response allows E. coli to repair its DNA but can also lead to increased mutagenesis.
This document provides a summary of a biology textbook chapter on DNA, genes, and genetic engineering. It discusses:
- The structure of DNA as a double helix made of nucleotides with complementary base pairing.
- Genes are segments of DNA that code for proteins. DNA is transcribed into mRNA which is translated by ribosomes into polypeptides.
- Genetic engineering techniques allow genes to be transferred between organisms using vectors like plasmids. The process of inserting the human insulin gene into bacteria to produce insulin is described.
DNA repair mechanisms are essential for maintaining genomic integrity. There are several pathways for repairing different types of DNA damage: mismatch repair fixes errors during DNA replication, base excision repair removes damaged bases, nucleotide excision repair replaces larger sections of damaged DNA, and double-strand break repair fixes breaks in both DNA strands. Defects in DNA repair genes can lead to increased cancer risks and genetic disorders like xeroderma pigmentosum and Fanconi anemia. Overall, DNA repair helps prevent mutations from being passed to new cells.
The molecular basis of inheritance class 12Anurag Verma
James Watson and Francis Crick discovered that DNA has a double helix structure in 1953. DNA contains the genetic instructions that are used to direct the development and function of living organisms. It was shown that DNA is the genetic material that is faithfully copied and passed from parents to offspring. The four bases in DNA are adenine, thymine, guanine, and cytosine, which bond together in DNA in a specific pairing between bases to form the double helix structure.
Chapter 20 Molecular Genetics Lesson 1 - Structure of DNAj3di79
This document provides an overview of molecular genetics content including:
(1) The structure of DNA and how it is organized in cells, with DNA made up of nucleotides containing bases, sugar, and phosphate that form two parallel strands twisted into a double helix.
(2) How genes and DNA are related, with each gene made up of a sequence of nucleotides that can vary, leading to different genes, and DNA containing the genetic information for cellular functions.
(3) The rules of complementary base pairing between nucleotides, with adenine binding thymine and cytosine binding guanine.
The document summarizes a workshop that taught how proteins are formed in the body from DNA. DNA contains genetic codes that determine the structure and function of proteins and other cellular components. During the workshop, students extracted DNA from cheek cells and used techniques like PCR and electrophoresis to replicate and separate DNA, demonstrating how specific genes and proteins are identified. These techniques have various applications in forensics, research, genetic engineering, and paleontology.
This document summarizes molecular basis of mutations. It defines mutations as changes in genetic information and describes different types of mutations including point mutations, chromosomal mutations, germline mutations and somatic mutations. It also discusses various mutagens responsible for mutations like chemical mutagens such as alkylating agents, base analogs and reactive oxygen species, and physical mutagens like UV radiation and ionizing radiation. The mechanisms of different mutagens and types of mutations based on their phenotypic effects are also summarized.
DNA replication requires four main components: DNA template, DNA polymerase, dNTPs, and magnesium ions. DNA unwinds and polymerase adds nucleotides based on complementary base pairing. DNA polymerase can only add to 3' ends so replication occurs in both directions from an origin of replication to yield two identical daughter DNA molecules. Topoisomerases are needed to resolve supercoiling that occurs during unwinding. Telomerase adds repeated sequences to chromosome ends during replication to compensate for incomplete end replication. DNA proofreading and mismatch repair help ensure high-fidelity copying of the genome.
Watson and Crick proposed a model of DNA structure in 1953 as a double helix with two antiparallel strands coiled around the same axis. Each strand consists of alternating deoxyribose and phosphate groups with purine or pyrimidine bases stacked inside. Adenine always pairs with thymine via two hydrogen bonds and guanine pairs with cytosine via three hydrogen bonds. Their model explained experimental X-ray diffraction data and Chargaff's rules of base equivalence. The discovery revolutionized our understanding of genetics and heredity.
This document provides an overview of microbial genetics concepts. It defines key terms like genetics, genes, chromosomes, and genomes. It describes the structure of DNA and the processes of DNA replication, transcription, and translation. It explains how genetic material is inherited vertically but can also be transferred horizontally between organisms through transformation, transduction, and conjugation. Mechanisms of genetic regulation, mutation, and repair are also summarized. The document uses diagrams and tables to illustrate these fundamental concepts in microbial genetics.
This document provides an overview of molecular biology and DNA structure. It defines molecular biology as the study of the structure, function and manipulation of nucleic acids and proteins. It then describes the key components of DNA, including the nitrogenous bases (adenine, guanine, cytosine, thymine), deoxyribose sugar, and phosphate groups. It explains that DNA exists as a double helix with the two polynucleotide chains associated through hydrogen bonding between complementary bases (A pairs with T, C pairs with G). The document also summarizes DNA replication as a semiconservative process where each new double helix contains one original and one new strand.
The document discusses the flow of genetic information from DNA to protein. It describes how DNA contains the genetic code in the form of nucleotide sequences. During transcription, DNA directs the synthesis of messenger RNA (mRNA). Translation then uses the mRNA to synthesize polypeptides through the ribosome. George Beadle and Edward Tatum provided evidence supporting the "one gene-one enzyme" hypothesis through experiments with bread mold mutants. Their work showed that each gene directs the production of a specific enzyme.
Polymerase chain reaction (PCR) is a technique used to amplify a specific region of DNA through repeated cycles of heating and cooling. It requires a DNA template, primers, DNA polymerase, nucleotides, and magnesium chloride. The process involves denaturation of the DNA strands, annealing of primers to the complementary sequences, and extension of the primers by DNA polymerase to synthesize new strands. PCR can be used to amplify small amounts of DNA for forensic analysis or isolate a known gene from a genome. However, it is limited to amplifying up to 5kb of known DNA sequences.
Lec 10 level 3-de (dna structure and replication)dream10f
The document discusses DNA structure and replication. It describes how DNA is composed of nucleotides that combine to form the characteristic double helix structure. The four nucleotides are adenine, guanine, cytosine, and thymine which pair up through hydrogen bonding in a specific way. DNA replication is semi-conservative and precisely copies the genetic information for cell division. It involves unwinding of the DNA double helix, synthesis of new complementary strands, and production of two identical DNA molecules each composed of one original and one new strand.
This document discusses gene expression and regulation. It begins by defining key terms like genes, genome, and gene expression. It then explains that organisms adapt to their environment by altering gene expression. There are two main types of gene expression: positive regulation which increases expression, and negative regulation which decreases it. Gene expression is studied in detail in prokaryotes using the lactose operon in E. coli as an example. Gene expression in eukaryotes is more complex due to larger genomes and separation of DNA and protein synthesis by the nuclear membrane.
The document appears to be in Spanish and discusses an exam or test for an infant. It is unclear from the limited information what the specific topic or subject of the exam was. More context would be needed to provide a more detailed summary.
El documento proporciona los datos personales de una persona incluyendo su dirección, número de teléfono, cédula, correo electrónico y nacionalidad, además de su educación primaria, secundaria y superior.
Este documento analiza la organización militar empleada por Francisco de Miranda durante su mandato como Generalísimo de la Primera República Venezolana entre 1811 y 1812. Se basaba en modelos similares a dictaduras republicanas antiguas, con un ejército dividido en milicias como las sociedades comerciales. Esto resultó en el entumecimiento del ejército debido a la inoperatividad del modelo y la resistencia de los cuadros de mando formados en nuevas técnicas militares. Estas diferencias generaron tensiones que paral
O documento lista sete "sapatos sujos" de preconceitos que precisamos deixar para trás para entrar na modernidade, incluindo a idéia de que os culpados são sempre os outros, que o sucesso não vem do trabalho, e que criticar é ser inimigo.
Sistemas operativos windows, mac y linuxmellamolaura
Este documento proporciona una breve introducción a los sistemas operativos Windows, Mac y Linux. Describe algunas de las diferencias clave entre Windows 7 y 8, como la interfaz moderna de Windows 8 y la eliminación del botón de inicio. Explica que Mac OS X Lion mantiene una interfaz similar a versiones anteriores pero introduce nuevas funciones como Mission Control. Finalmente, señala que Linux se ha vuelto más funcional y popular debido a su estabilidad, versatilidad y soporte de empresas, y que su futuro puede estar en la nube.
(1) O documento discute números complexos, que podem ser escritos na forma z = x + iy, onde x e y são números reais e i é a unidade imaginária tal que i2 = -1.
(2) Explica como realizar operações como adição, subtração, multiplicação e divisão com números complexos.
(3) Apresenta exemplos de resolução de raízes negativas e cálculos com números complexos complexos.
O poeta Olavo Bilac escreve um anúncio para venda de um sítio de um amigo de forma poética, descrevendo suas belezas naturais. Após ler o anúncio, o dono percebe o valor do que possuía e desiste de vendê-lo. O texto reflete sobre valorizarmos o que temos em nossa vida, como família, saúde e amigos, em vez de buscarmos falsos tesouros.
O documento discute a importância de não se sentir ofendido facilmente, valorizar a amizade e ajudar os outros. Também enfatiza praticar a caridade, não julgar os outros e fazer o bem sem adiar.
O documento fornece 20 dicas para crescimento pessoal. A dica número 20 enfatiza que cada um é responsável por se tornar aquilo que deseja ser e que depende apenas de seus próprios esforços.
El documento lista diferentes fuentes tipográficas y sus tamaños respectivos, incluyendo AmerType Md BT tamaño 20, Castellar tamaño 22, Cooper Black tamaño 14, Formal436 BT tamaño 22, Informal Roman tamaño 26, Modern No. 20 tamaño 10, Playbill tamaño 24 y Script MT Bold tamaño 20.
Chapter 20 Molecular Genetics Lesson 1 - Structure of DNAj3di79
This document provides an overview of molecular genetics content including:
(1) The structure of DNA and how it is organized in cells, with DNA made up of nucleotides containing bases, sugar, and phosphate that form two parallel strands twisted into a double helix.
(2) How genes and DNA are related, with each gene made up of a sequence of nucleotides that can vary, leading to different genes, and DNA containing the genetic information for cellular functions.
(3) The rules of complementary base pairing between nucleotides, with adenine binding thymine and cytosine binding guanine.
The document summarizes a workshop that taught how proteins are formed in the body from DNA. DNA contains genetic codes that determine the structure and function of proteins and other cellular components. During the workshop, students extracted DNA from cheek cells and used techniques like PCR and electrophoresis to replicate and separate DNA, demonstrating how specific genes and proteins are identified. These techniques have various applications in forensics, research, genetic engineering, and paleontology.
This document summarizes molecular basis of mutations. It defines mutations as changes in genetic information and describes different types of mutations including point mutations, chromosomal mutations, germline mutations and somatic mutations. It also discusses various mutagens responsible for mutations like chemical mutagens such as alkylating agents, base analogs and reactive oxygen species, and physical mutagens like UV radiation and ionizing radiation. The mechanisms of different mutagens and types of mutations based on their phenotypic effects are also summarized.
DNA replication requires four main components: DNA template, DNA polymerase, dNTPs, and magnesium ions. DNA unwinds and polymerase adds nucleotides based on complementary base pairing. DNA polymerase can only add to 3' ends so replication occurs in both directions from an origin of replication to yield two identical daughter DNA molecules. Topoisomerases are needed to resolve supercoiling that occurs during unwinding. Telomerase adds repeated sequences to chromosome ends during replication to compensate for incomplete end replication. DNA proofreading and mismatch repair help ensure high-fidelity copying of the genome.
Watson and Crick proposed a model of DNA structure in 1953 as a double helix with two antiparallel strands coiled around the same axis. Each strand consists of alternating deoxyribose and phosphate groups with purine or pyrimidine bases stacked inside. Adenine always pairs with thymine via two hydrogen bonds and guanine pairs with cytosine via three hydrogen bonds. Their model explained experimental X-ray diffraction data and Chargaff's rules of base equivalence. The discovery revolutionized our understanding of genetics and heredity.
This document provides an overview of microbial genetics concepts. It defines key terms like genetics, genes, chromosomes, and genomes. It describes the structure of DNA and the processes of DNA replication, transcription, and translation. It explains how genetic material is inherited vertically but can also be transferred horizontally between organisms through transformation, transduction, and conjugation. Mechanisms of genetic regulation, mutation, and repair are also summarized. The document uses diagrams and tables to illustrate these fundamental concepts in microbial genetics.
This document provides an overview of molecular biology and DNA structure. It defines molecular biology as the study of the structure, function and manipulation of nucleic acids and proteins. It then describes the key components of DNA, including the nitrogenous bases (adenine, guanine, cytosine, thymine), deoxyribose sugar, and phosphate groups. It explains that DNA exists as a double helix with the two polynucleotide chains associated through hydrogen bonding between complementary bases (A pairs with T, C pairs with G). The document also summarizes DNA replication as a semiconservative process where each new double helix contains one original and one new strand.
The document discusses the flow of genetic information from DNA to protein. It describes how DNA contains the genetic code in the form of nucleotide sequences. During transcription, DNA directs the synthesis of messenger RNA (mRNA). Translation then uses the mRNA to synthesize polypeptides through the ribosome. George Beadle and Edward Tatum provided evidence supporting the "one gene-one enzyme" hypothesis through experiments with bread mold mutants. Their work showed that each gene directs the production of a specific enzyme.
Polymerase chain reaction (PCR) is a technique used to amplify a specific region of DNA through repeated cycles of heating and cooling. It requires a DNA template, primers, DNA polymerase, nucleotides, and magnesium chloride. The process involves denaturation of the DNA strands, annealing of primers to the complementary sequences, and extension of the primers by DNA polymerase to synthesize new strands. PCR can be used to amplify small amounts of DNA for forensic analysis or isolate a known gene from a genome. However, it is limited to amplifying up to 5kb of known DNA sequences.
Lec 10 level 3-de (dna structure and replication)dream10f
The document discusses DNA structure and replication. It describes how DNA is composed of nucleotides that combine to form the characteristic double helix structure. The four nucleotides are adenine, guanine, cytosine, and thymine which pair up through hydrogen bonding in a specific way. DNA replication is semi-conservative and precisely copies the genetic information for cell division. It involves unwinding of the DNA double helix, synthesis of new complementary strands, and production of two identical DNA molecules each composed of one original and one new strand.
This document discusses gene expression and regulation. It begins by defining key terms like genes, genome, and gene expression. It then explains that organisms adapt to their environment by altering gene expression. There are two main types of gene expression: positive regulation which increases expression, and negative regulation which decreases it. Gene expression is studied in detail in prokaryotes using the lactose operon in E. coli as an example. Gene expression in eukaryotes is more complex due to larger genomes and separation of DNA and protein synthesis by the nuclear membrane.
The document appears to be in Spanish and discusses an exam or test for an infant. It is unclear from the limited information what the specific topic or subject of the exam was. More context would be needed to provide a more detailed summary.
El documento proporciona los datos personales de una persona incluyendo su dirección, número de teléfono, cédula, correo electrónico y nacionalidad, además de su educación primaria, secundaria y superior.
Este documento analiza la organización militar empleada por Francisco de Miranda durante su mandato como Generalísimo de la Primera República Venezolana entre 1811 y 1812. Se basaba en modelos similares a dictaduras republicanas antiguas, con un ejército dividido en milicias como las sociedades comerciales. Esto resultó en el entumecimiento del ejército debido a la inoperatividad del modelo y la resistencia de los cuadros de mando formados en nuevas técnicas militares. Estas diferencias generaron tensiones que paral
O documento lista sete "sapatos sujos" de preconceitos que precisamos deixar para trás para entrar na modernidade, incluindo a idéia de que os culpados são sempre os outros, que o sucesso não vem do trabalho, e que criticar é ser inimigo.
Sistemas operativos windows, mac y linuxmellamolaura
Este documento proporciona una breve introducción a los sistemas operativos Windows, Mac y Linux. Describe algunas de las diferencias clave entre Windows 7 y 8, como la interfaz moderna de Windows 8 y la eliminación del botón de inicio. Explica que Mac OS X Lion mantiene una interfaz similar a versiones anteriores pero introduce nuevas funciones como Mission Control. Finalmente, señala que Linux se ha vuelto más funcional y popular debido a su estabilidad, versatilidad y soporte de empresas, y que su futuro puede estar en la nube.
(1) O documento discute números complexos, que podem ser escritos na forma z = x + iy, onde x e y são números reais e i é a unidade imaginária tal que i2 = -1.
(2) Explica como realizar operações como adição, subtração, multiplicação e divisão com números complexos.
(3) Apresenta exemplos de resolução de raízes negativas e cálculos com números complexos complexos.
O poeta Olavo Bilac escreve um anúncio para venda de um sítio de um amigo de forma poética, descrevendo suas belezas naturais. Após ler o anúncio, o dono percebe o valor do que possuía e desiste de vendê-lo. O texto reflete sobre valorizarmos o que temos em nossa vida, como família, saúde e amigos, em vez de buscarmos falsos tesouros.
O documento discute a importância de não se sentir ofendido facilmente, valorizar a amizade e ajudar os outros. Também enfatiza praticar a caridade, não julgar os outros e fazer o bem sem adiar.
O documento fornece 20 dicas para crescimento pessoal. A dica número 20 enfatiza que cada um é responsável por se tornar aquilo que deseja ser e que depende apenas de seus próprios esforços.
El documento lista diferentes fuentes tipográficas y sus tamaños respectivos, incluyendo AmerType Md BT tamaño 20, Castellar tamaño 22, Cooper Black tamaño 14, Formal436 BT tamaño 22, Informal Roman tamaño 26, Modern No. 20 tamaño 10, Playbill tamaño 24 y Script MT Bold tamaño 20.
A história descreve duas moscas que caem em copos diferentes. A primeira mosca desiste quando não consegue sair do copo de leite, enquanto a segunda mosca persiste e forma manteiga para escapar. Posteriormente, quando a segunda mosca cai em um copo de água, ela tenta repetir a mesma estratégia, ignorando que a situação mudou, e acaba afundando. A lição é que soluções do passado podem não funcionar em novos contextos, e é preciso estar aberto a novas abordagens.
Este documento discute os processos de tratamento térmico e revestimento usados em ferramentas de trabalho a frio como estampagem e corte. Ele explica que aços como D2 e D6 precisam de têmpera e revenimento para melhorar suas propriedades mecânicas, e que processos como nitretação e revestimento PVD podem melhorar ainda mais as propriedades superficiais. Ele também ressalta a importância de comunicar os parâmetros do tratamento térmico original para que processos subsequentes como nitretação e PVD sejam realiz
The document is a matching activity that pairs pictures with words describing common life events from a word bank, such as getting married, having children, graduating college, starting a business, and going on vacation. Learners are instructed to write the matching words under corresponding pictures.
Compu Dynamics White Paper - Essential Elements for Data Center OptimizationDan Ephraim
This white paper discusses essential elements for optimizing data center operations, including airflow management, data center infrastructure management (DCIM) tools, power management, and operational best practices. It focuses on recent government initiatives like the Data Center Optimization Initiative (DCOI) that mandate increased energy efficiency in federal data centers through metrics like power usage effectiveness (PUE). The paper examines strategies like hot/cold aisle containment and cloud migration that can help data centers improve optimization and meet new efficiency requirements.
Colonization of other people and countries occurred for exploitative reasons like capturing slaves, stealing land and resources to gain wealth. The Spanish colonized much of the Americas to do this, and today Latin Americans descend from both European and native American heritage. Globalization originated from colonization as colonized peoples adopted the colonizers' language and religion, and now as the world globalizes more, traditional cultures may disappear as places grow more American and European.
This document summarizes evidence that supports the theory of evolution from four perspectives: biogeography, the age of the Earth and fossils, comparative anatomy and embryology, and genetics and molecular biology. Each section provides examples for how scientific observations in these areas help trace evolutionary relationships and document how species have changed over time from common ancestors through natural processes like natural selection. The document also discusses how recent research on Galapagos finches supported Darwin's original hypotheses about natural selection by showing adaptations to seasonal changes.
The asmat creation_story_fumeripits_createsrprovenci001
Fumeripits, the first being on earth, created humans from trees to end his loneliness. He carved human figures from trees and placed them in a ceremonial house, but they were inanimate. Fumeripits then created a drum from a hollowed tree and brought the figures to life by playing music, allowing the first people, the Asmat, to dance.
The Asmat are an indigenous hunter-gatherer culture living in West Papua, Indonesia, on an island north of Australia in the South Pacific Ocean. They are one of the last remaining hunter-gatherer cultures in the world, with traditions including nose piercing and painting faces and bodies for ceremonies and war. However, deforestation, colonization, and assimilation are negatively impacting traditional Asmat culture, potentially bringing an end to one of Earth's last hunter-gatherer societies as the modern world influences their way of life.
1) According to Maori tradition, all humans are descended from the primordial pair Rangi (sky father) and Papa (earth mother) who were locked in a close embrace, leaving the world in darkness.
2) Rangi and Papa had six sons representing different domains who lived for a long time in darkness, unable to experience light.
3) After a battle between the six sons, Tu-matauenga ate four of his brothers, sparing Tawhiri-ma-tea, the god of winds and storms. This explains humanity's fierce and warlike nature as well as our relationship with the natural world through eating plants, animals, and experiencing
The Maori creation story describes how all humans are descended from the primordial parents Rangi (sky father) and Papa (earth mother). In the beginning, Rangi and Papa clung closely together in darkness. They had six sons: Tane-mahuta (god of forests), Tawhirl-ma-tea (god of winds), Tangaroa (god of sea), Tu-matauenga (god of war), Haumia-tikitiki (god of uncultivated food) and Rongo-ma-tane (god of cultivated food). The sons lived for a long time in darkness until Tu-matauenga ate four brothers, sparing only Tawhi
DNA molecules are located in the cytoplasm in prokaryotes, while in eukaryotes nearly all DNA is found in the nucleus. DNA polymerase is the main enzyme that links individual nucleotides into DNA molecules during replication, as shown by the diagram.
DNA stores, sends, and copies information in our cells. It contains the genetic instructions that determine physical traits and development. DNA is found in almost every cell in our bodies and is the building block of life.
DNA contains phosphate groups that are essential parts of its structure. The phosphate group contains an oxygen atom and a phosphorous atom. Together, the oxygen and phosphorous make up the phosphate group in DNA.
Contemporary traditional maori_culture_part_1rprovenci001
The Maori are the indigenous people of New Zealand, living on the large island in the South Pacific Ocean off the southeast coast of Australia. While some Maori continue traditional cultural practices like the Haka war dance ceremony and moko facial tattoos, others have adopted non-traditional modern lifestyles, and as a conquered people some Maori still struggle with issues like poverty, alcoholism, and drug abuse.
The document defines and provides examples of several key terms: contemporary (modern artist Adele), geographic isolation (climbers in the Himalayas cut off), traditional (family Christmas tree tradition), and anthropology (Mr. Meza's teacher). It also gives examples of isolated groups that maintain traditions of hunting and gathering, like the Yanomami blocked by jungle and the San people surrounded by sand dunes.
Deforestation and pollution are harming the environment in major ways. Deforestation is killing forests and the earth, while pollution is killing beaches. We should respect forests and work to reduce deforestation and pollution that damage the environment.
Full-RAG: A modern architecture for hyper-personalizationZilliz
Mike Del Balso, CEO & Co-Founder at Tecton, presents "Full RAG," a novel approach to AI recommendation systems, aiming to push beyond the limitations of traditional models through a deep integration of contextual insights and real-time data, leveraging the Retrieval-Augmented Generation architecture. This talk will outline Full RAG's potential to significantly enhance personalization, address engineering challenges such as data management and model training, and introduce data enrichment with reranking as a key solution. Attendees will gain crucial insights into the importance of hyperpersonalization in AI, the capabilities of Full RAG for advanced personalization, and strategies for managing complex data integrations for deploying cutting-edge AI solutions.
Encryption in Microsoft 365 - ExpertsLive Netherlands 2024Albert Hoitingh
In this session I delve into the encryption technology used in Microsoft 365 and Microsoft Purview. Including the concepts of Customer Key and Double Key Encryption.
Alt. GDG Cloud Southlake #33: Boule & Rebala: Effective AppSec in SDLC using ...James Anderson
Effective Application Security in Software Delivery lifecycle using Deployment Firewall and DBOM
The modern software delivery process (or the CI/CD process) includes many tools, distributed teams, open-source code, and cloud platforms. Constant focus on speed to release software to market, along with the traditional slow and manual security checks has caused gaps in continuous security as an important piece in the software supply chain. Today organizations feel more susceptible to external and internal cyber threats due to the vast attack surface in their applications supply chain and the lack of end-to-end governance and risk management.
The software team must secure its software delivery process to avoid vulnerability and security breaches. This needs to be achieved with existing tool chains and without extensive rework of the delivery processes. This talk will present strategies and techniques for providing visibility into the true risk of the existing vulnerabilities, preventing the introduction of security issues in the software, resolving vulnerabilities in production environments quickly, and capturing the deployment bill of materials (DBOM).
Speakers:
Bob Boule
Robert Boule is a technology enthusiast with PASSION for technology and making things work along with a knack for helping others understand how things work. He comes with around 20 years of solution engineering experience in application security, software continuous delivery, and SaaS platforms. He is known for his dynamic presentations in CI/CD and application security integrated in software delivery lifecycle.
Gopinath Rebala
Gopinath Rebala is the CTO of OpsMx, where he has overall responsibility for the machine learning and data processing architectures for Secure Software Delivery. Gopi also has a strong connection with our customers, leading design and architecture for strategic implementations. Gopi is a frequent speaker and well-known leader in continuous delivery and integrating security into software delivery.
Generative AI Deep Dive: Advancing from Proof of Concept to ProductionAggregage
Join Maher Hanafi, VP of Engineering at Betterworks, in this new session where he'll share a practical framework to transform Gen AI prototypes into impactful products! He'll delve into the complexities of data collection and management, model selection and optimization, and ensuring security, scalability, and responsible use.
For the full video of this presentation, please visit: https://www.edge-ai-vision.com/2024/06/building-and-scaling-ai-applications-with-the-nx-ai-manager-a-presentation-from-network-optix/
Robin van Emden, Senior Director of Data Science at Network Optix, presents the “Building and Scaling AI Applications with the Nx AI Manager,” tutorial at the May 2024 Embedded Vision Summit.
In this presentation, van Emden covers the basics of scaling edge AI solutions using the Nx tool kit. He emphasizes the process of developing AI models and deploying them globally. He also showcases the conversion of AI models and the creation of effective edge AI pipelines, with a focus on pre-processing, model conversion, selecting the appropriate inference engine for the target hardware and post-processing.
van Emden shows how Nx can simplify the developer’s life and facilitate a rapid transition from concept to production-ready applications.He provides valuable insights into developing scalable and efficient edge AI solutions, with a strong focus on practical implementation.
Removing Uninteresting Bytes in Software FuzzingAftab Hussain
Imagine a world where software fuzzing, the process of mutating bytes in test seeds to uncover hidden and erroneous program behaviors, becomes faster and more effective. A lot depends on the initial seeds, which can significantly dictate the trajectory of a fuzzing campaign, particularly in terms of how long it takes to uncover interesting behaviour in your code. We introduce DIAR, a technique designed to speedup fuzzing campaigns by pinpointing and eliminating those uninteresting bytes in the seeds. Picture this: instead of wasting valuable resources on meaningless mutations in large, bloated seeds, DIAR removes the unnecessary bytes, streamlining the entire process.
In this work, we equipped AFL, a popular fuzzer, with DIAR and examined two critical Linux libraries -- Libxml's xmllint, a tool for parsing xml documents, and Binutil's readelf, an essential debugging and security analysis command-line tool used to display detailed information about ELF (Executable and Linkable Format). Our preliminary results show that AFL+DIAR does not only discover new paths more quickly but also achieves higher coverage overall. This work thus showcases how starting with lean and optimized seeds can lead to faster, more comprehensive fuzzing campaigns -- and DIAR helps you find such seeds.
- These are slides of the talk given at IEEE International Conference on Software Testing Verification and Validation Workshop, ICSTW 2022.
TrustArc Webinar - 2024 Global Privacy SurveyTrustArc
How does your privacy program stack up against your peers? What challenges are privacy teams tackling and prioritizing in 2024?
In the fifth annual Global Privacy Benchmarks Survey, we asked over 1,800 global privacy professionals and business executives to share their perspectives on the current state of privacy inside and outside of their organizations. This year’s report focused on emerging areas of importance for privacy and compliance professionals, including considerations and implications of Artificial Intelligence (AI) technologies, building brand trust, and different approaches for achieving higher privacy competence scores.
See how organizational priorities and strategic approaches to data security and privacy are evolving around the globe.
This webinar will review:
- The top 10 privacy insights from the fifth annual Global Privacy Benchmarks Survey
- The top challenges for privacy leaders, practitioners, and organizations in 2024
- Key themes to consider in developing and maintaining your privacy program
In the rapidly evolving landscape of technologies, XML continues to play a vital role in structuring, storing, and transporting data across diverse systems. The recent advancements in artificial intelligence (AI) present new methodologies for enhancing XML development workflows, introducing efficiency, automation, and intelligent capabilities. This presentation will outline the scope and perspective of utilizing AI in XML development. The potential benefits and the possible pitfalls will be highlighted, providing a balanced view of the subject.
We will explore the capabilities of AI in understanding XML markup languages and autonomously creating structured XML content. Additionally, we will examine the capacity of AI to enrich plain text with appropriate XML markup. Practical examples and methodological guidelines will be provided to elucidate how AI can be effectively prompted to interpret and generate accurate XML markup.
Further emphasis will be placed on the role of AI in developing XSLT, or schemas such as XSD and Schematron. We will address the techniques and strategies adopted to create prompts for generating code, explaining code, or refactoring the code, and the results achieved.
The discussion will extend to how AI can be used to transform XML content. In particular, the focus will be on the use of AI XPath extension functions in XSLT, Schematron, Schematron Quick Fixes, or for XML content refactoring.
The presentation aims to deliver a comprehensive overview of AI usage in XML development, providing attendees with the necessary knowledge to make informed decisions. Whether you’re at the early stages of adopting AI or considering integrating it in advanced XML development, this presentation will cover all levels of expertise.
By highlighting the potential advantages and challenges of integrating AI with XML development tools and languages, the presentation seeks to inspire thoughtful conversation around the future of XML development. We’ll not only delve into the technical aspects of AI-powered XML development but also discuss practical implications and possible future directions.
Observability Concepts EVERY Developer Should Know -- DeveloperWeek Europe.pdfPaige Cruz
Monitoring and observability aren’t traditionally found in software curriculums and many of us cobble this knowledge together from whatever vendor or ecosystem we were first introduced to and whatever is a part of your current company’s observability stack.
While the dev and ops silo continues to crumble….many organizations still relegate monitoring & observability as the purview of ops, infra and SRE teams. This is a mistake - achieving a highly observable system requires collaboration up and down the stack.
I, a former op, would like to extend an invitation to all application developers to join the observability party will share these foundational concepts to build on:
Threats to mobile devices are more prevalent and increasing in scope and complexity. Users of mobile devices desire to take full advantage of the features
available on those devices, but many of the features provide convenience and capability but sacrifice security. This best practices guide outlines steps the users can take to better protect personal devices and information.
A tale of scale & speed: How the US Navy is enabling software delivery from l...sonjaschweigert1
Rapid and secure feature delivery is a goal across every application team and every branch of the DoD. The Navy’s DevSecOps platform, Party Barge, has achieved:
- Reduction in onboarding time from 5 weeks to 1 day
- Improved developer experience and productivity through actionable findings and reduction of false positives
- Maintenance of superior security standards and inherent policy enforcement with Authorization to Operate (ATO)
Development teams can ship efficiently and ensure applications are cyber ready for Navy Authorizing Officials (AOs). In this webinar, Sigma Defense and Anchore will give attendees a look behind the scenes and demo secure pipeline automation and security artifacts that speed up application ATO and time to production.
We will cover:
- How to remove silos in DevSecOps
- How to build efficient development pipeline roles and component templates
- How to deliver security artifacts that matter for ATO’s (SBOMs, vulnerability reports, and policy evidence)
- How to streamline operations with automated policy checks on container images
Unlock the Future of Search with MongoDB Atlas_ Vector Search Unleashed.pdfMalak Abu Hammad
Discover how MongoDB Atlas and vector search technology can revolutionize your application's search capabilities. This comprehensive presentation covers:
* What is Vector Search?
* Importance and benefits of vector search
* Practical use cases across various industries
* Step-by-step implementation guide
* Live demos with code snippets
* Enhancing LLM capabilities with vector search
* Best practices and optimization strategies
Perfect for developers, AI enthusiasts, and tech leaders. Learn how to leverage MongoDB Atlas to deliver highly relevant, context-aware search results, transforming your data retrieval process. Stay ahead in tech innovation and maximize the potential of your applications.
#MongoDB #VectorSearch #AI #SemanticSearch #TechInnovation #DataScience #LLM #MachineLearning #SearchTechnology
“An Outlook of the Ongoing and Future Relationship between Blockchain Technologies and Process-aware Information Systems.” Invited talk at the joint workshop on Blockchain for Information Systems (BC4IS) and Blockchain for Trusted Data Sharing (B4TDS), co-located with with the 36th International Conference on Advanced Information Systems Engineering (CAiSE), 3 June 2024, Limassol, Cyprus.
Let's Integrate MuleSoft RPA, COMPOSER, APM with AWS IDP along with Slackshyamraj55
Discover the seamless integration of RPA (Robotic Process Automation), COMPOSER, and APM with AWS IDP enhanced with Slack notifications. Explore how these technologies converge to streamline workflows, optimize performance, and ensure secure access, all while leveraging the power of AWS IDP and real-time communication via Slack notifications.
UiPath Test Automation using UiPath Test Suite series, part 6DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 6. In this session, we will cover Test Automation with generative AI and Open AI.
UiPath Test Automation with generative AI and Open AI webinar offers an in-depth exploration of leveraging cutting-edge technologies for test automation within the UiPath platform. Attendees will delve into the integration of generative AI, a test automation solution, with Open AI advanced natural language processing capabilities.
Throughout the session, participants will discover how this synergy empowers testers to automate repetitive tasks, enhance testing accuracy, and expedite the software testing life cycle. Topics covered include the seamless integration process, practical use cases, and the benefits of harnessing AI-driven automation for UiPath testing initiatives. By attending this webinar, testers, and automation professionals can gain valuable insights into harnessing the power of AI to optimize their test automation workflows within the UiPath ecosystem, ultimately driving efficiency and quality in software development processes.
What will you get from this session?
1. Insights into integrating generative AI.
2. Understanding how this integration enhances test automation within the UiPath platform
3. Practical demonstrations
4. Exploration of real-world use cases illustrating the benefits of AI-driven test automation for UiPath
Topics covered:
What is generative AI
Test Automation with generative AI and Open AI.
UiPath integration with generative AI
Speaker:
Deepak Rai, Automation Practice Lead, Boundaryless Group and UiPath MVP
Building RAG with self-deployed Milvus vector database and Snowpark Container...Zilliz
This talk will give hands-on advice on building RAG applications with an open-source Milvus database deployed as a docker container. We will also introduce the integration of Milvus with Snowpark Container Services.
1. warm-up
1.In prokaryotes,DNA molecules are located in the
c.cytoplasm
2.In eukaryote, nearly all the DNA is found in the
a.nucleus
3.The main enzyme involved in linking individual nucleotides into DNA molecule is
d. DNA polymerase
4.the diagram below shows the process of
a.replication