Untargeted Metabolomics
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Untargeted metabolomics is mainly conducted to comprehensively understand biochemical information metabolism in organisms. Using liquid chromatography-mass spectrometry technology, almost all metabolites under certain physiological or other specific conditions can be qualitatively and quantitatively analyzed for the identification of different metabolites. https://metabolomics.creative-proteomics.com/untargeted-metabolomics-service.htm
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- 11. ‚ ƒ • Chromatographic separa�on • MS ioniza�on (nega�ve and posi- �ve modes) (EI, ESI, APCI, MALDI) • Mass detec�on Global metabolite extrac�on: a. Hydrophobic frac�on: C18 Column b. Hydrophiic frac�on: HILIC Column Deriva�za�on (op�onal) • Data preprocessing: noise filtering, reten�on �me correc�on, peak detec�on, chromatogram alignment, unknown features/metabolite iden�- fica�on • Data prepara�on: data integrity checking. data IS normaliza�on, compound name iden�fica�on Why choose it? „ …€ ‚ m/z Intensity † ‡ • PCA • Heat map • Box-whisker plot • Enrichment analysis • Correla�on analysis • Metabolic pathway ˆ‚ ˆ‰
- 13. Why choose untargeted metabolomics? Contact Us