This document summarizes a presentation given in Piza, Italy on understanding changing patterns of drug use in Georgia and their implications. It provides background information on Georgia including drug use statistics showing a shift from traditional opioids to homemade stimulants and opioids. It describes features of Georgia's drug scene, how trends are shaped by socioeconomic factors, and associated health harms like HIV. The response has been inadequate treatment and disproportionate spending on enforcement versus healthcare. Major policy reforms are needed including developing a national drug strategy with healthcare professional engagement.