2. Outermost / Cell membrane.
Thickness is about 5-8 nm.
Selectively permeable.
Serves as outer boundary.
Made up of Phospholipids, Proteins, and
conjugated molecules.
Separate and protect cell from external
environment.
3. Proposed in 1972, by Singer and Nicolson.
“Cell membrane is lipid bilayer in which
proteins are partially embedded like floating
icebergs in sea.”
It describes the plasma membrane as a
flexible boundary of a cell. The phospholipids
move within the membrane.
4.
5. The plasma membrane is composed of two
layers of phospholipids back-to-back.
It consists of some components:-
i. Phospholipids
ii. Peripheral (extrinsic) protein
iii. Integral (Intrinsic) protein
iv. Cholesterol
v. Glycoprotein
vi. Glycolipid
6.
7. Phospholipids are lipids with a phosphate
attached to them. They have fatty acid tails
(hydrophobic) and phosphate group head
(hydrophilic) arranged as a bilayer.
Phospholipids, glycolipids, cholesterol are
amphipathic lipids containing hydrophobic
and hydrophilic ends.
8. Also called as
Peripheral Protein.
Proteins loosely
associated with
membrane surface.
Located entirely
outside of the lipid
bilayer.
Either on the
extracellular or
cytoplasmic surface.
Also called as
Integral Protein.
Tightly bound to
lipid layer.
Provides channel for
the water-soluble
substances
9. Transport proteins allow needed substances
or waste materials to move through the
plasma membrane.
10. ACTIVE TRANSPORT PASSIVE TRANSPORT
Diffusion against
concentration
gradient.
Low High
Uses a protein
pump.
Requires ATP.
SIMPLE diffusion
i. Diffusion of non-
polar, hydrophobic
molecules (lipids)
ii. High Low
FACILIATED
diffusion
i. Diffusion of polar,
hydrophilic
molecules.
ii. Through a protein
channel.
iii. High Low