SlideShare a Scribd company logo
Transdel Pharmaceuticals, Inc . ,[object Object],[object Object]
Safe Harbor Statement ,[object Object]
Transdel Investment Highlights ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Transdel Management Team ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Epidermis Dermis Subcut. Tissue Muscle Transdermal Delivery System (TDS) ,[object Object],[object Object],[object Object],[object Object],[object Object],Transdelโ€™s proprietary cream formulation enables active drug  to penetrate the skin and reach targeted underlying tissue
Selected Pipeline *TDB โ€“ To Be Determined Program Target Status Partner(s) Launch Date Ketotransdel Pain (NSAID) Phase III TBD* TDLP310 Cellulite Subject Trials JH Direct & Jan Marini Skin Research Anticipate 2010 TDLP320 Anti-Aging Formulation TBD* TDLP330 Pigmentation Formulation TBD*
Therapeutic Value of Topical NSAIDs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Massey T, et al., Topical NSAIDs for acute pain in adults (Review),  published in The Cochrane Library 2010, Issue 6
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Lead Pain Drug Ketotransdel
Clinical Design:    Randomized, double-blind, placebo-controlled Study Population:  Patients with acute soft tissue injuries    (sprains & strains) Indication:  Relief of pain from acute soft tissue injuries Dosing Regimen:  Ketotransdel vs. Placebo (Vehicle) cream,  1g three times daily over 7 days Primary Endpoint:  Change from baseline in pain intensity on    Day 3 Visit (+1, +2 days) with VAS measurement Secondary Endpoints: Safety assessments, various other efficacy variables  Pharmacokinetics in subset of patients Clinical Sites: 26 (USA) Randomized: N=364 Ketotransdel   Phase 3 Trial
Ketotransdel demonstrated statistically significant  higher reduction in pain intensity from baseline in both the modified Intent-To-Treat (ITT) and Per Protocol (PP) analysis. PP (n=252) mITT (n=326) Mean reduction from baseline in mm (100 mm Visual Analogue Scale)   mm Reduction   in Pain Intensity from baseline on Day 3 Ketotransdel Phase 3 Trial TDLP-110-001:   Primary Efficacy Endpoint Results  *  p < 0.05 *  p = 0.038 * A nalysis of all  ITT patients who met study entry criteria ,  ANCOVA on change from baseline in pain intensity during daily  activities  over the past 24 hours on Day 3 Visit (Day 3, +1 or +2 days)
Ketotransdel Phase 3 Trial TDLP-110-001: Efficacy Endpoint:  Change from baseline in  three-times-daily pain intensity The Pain Curves over time show  consistent separation between treatment groups reaching statistical significance in favor of Ketotransdel in ITT analyses . * Time period that primary endpoint โ€œDay 3 Visitโ€ covers: Days 3, 4 and 5. * Ketotransdel Placebo
[object Object],[object Object],[object Object],[object Object],[object Object],Ketotransdel Phase 3 trial TDLP-110-001:  Safety and Pharmacokinetics Ketotransdel  (n= 182) Placebo  (n=182) All potentially related AEs: 4.1% 3.8% 4.4% Cutaneous/application site AEs 1.1 % 2.2%
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Ketotransdel Phase 3 trial TDLP-110-001 Conclusions
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Patients Who May Benefit From  a Topical NSAID
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],*Source: U.S. Transdermal Drug Delivery Markets, Frost and Sullivan, August 2006. Ketotransdel Market Opportunity
[object Object],[object Object],[object Object],[object Object],Note: Graphs denote total prescriptions, per IMS data. Total  Rx COX2s Vs. NSAIDs Topical NSAID (Diclofenac) TRx NSAID Market Dynamics
Competitive Landscape  FDA Approved Topical NSAIDs Product Indication Dosage Company Flector Patch 1.3% diclofenac  Acute Pain (strains & sprains) 10 x 14 cm patch, 2 times per day  King Pharma/ IBSA Voltaren Gel 1% diclofenac Osteoarthritis knee/ hands 2- 4 g qid (16g/d) ENDO/ Novartis Pennsaid 1.5% diclofenac Osteoarthritis knee 40 drops of liquid (10 drops to each of 4 sides of knee), 3-4 times per day  Covidien/ NUVO
US Sales of Flector Patch and Voltaren Gel  (in millions) FY 2008 FY  2009 FY 2010 (E) Flector Patch (1) $ 128  $ 139  $  180 Voltaren Gel (1) $  24  $  79 $  96 Pennsaid (2) โ€“ โ€“ N.A. $ 152  $  218  $  276 ,[object Object],[object Object],[object Object],Double digit growth estimated in 2010 for Flector and Voltaren Gel
Cosmeceuticals ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Select Financials Key Statistics Symbol: TDLP.OB Fiscal Year End: December 31 st Current Price (6/17/10): $1.20 Shares Outstanding: 15.7 million Market Cap: $19 million Proforma cash (as of 3/31/10) (1) $2.0 million ( 1) Includes $1M proceeds from convertible senior promissory note issued in April 2010.
Contact Us Transdel Pharmaceuticals, Inc . (OTC BB: TDLP.OB) 4225 Executive Square Suite 485 La Jolla, CA 92037 Corporate Headquarters Investor Contact John Lomoro Chief Financial Officer and Acting Chief Executive Officer (858) 457-5300 [email_address] Please visit www.transdelpharma.com for more information.

More Related Content

What's hot

EMERGING APPROACHES TO COMBINATION THERAPIES IN AMD & DME - Regeneron
EMERGING APPROACHES TO COMBINATION THERAPIES IN AMD & DME - RegeneronEMERGING APPROACHES TO COMBINATION THERAPIES IN AMD & DME - Regeneron
EMERGING APPROACHES TO COMBINATION THERAPIES IN AMD & DME - Regeneron
Healthegy
ย 
How to set up a TDM unit dr. Shakeeb Dhorajiwala
How to set up a TDM unit dr. Shakeeb Dhorajiwala How to set up a TDM unit dr. Shakeeb Dhorajiwala
How to set up a TDM unit dr. Shakeeb Dhorajiwala
Seth GSMC and KEM Municipal Hospital
ย 
Opexa therapeutics corporate presentation june 2014
Opexa therapeutics corporate presentation june 2014Opexa therapeutics corporate presentation june 2014
Opexa therapeutics corporate presentation june 2014OpexaTherapeutics
ย 
Opexa therapeutics corporate presentation june 2014 for print
Opexa therapeutics corporate presentation june 2014 for printOpexa therapeutics corporate presentation june 2014 for print
Opexa therapeutics corporate presentation june 2014 for print
RedChip Companies, Inc.
ย 
Opexa Therapeutics Corporate Presentation July 2014
Opexa Therapeutics Corporate Presentation July 2014Opexa Therapeutics Corporate Presentation July 2014
Opexa Therapeutics Corporate Presentation July 2014
OpexaTherapeutics
ย 
Androgel Safety Information
Androgel Safety InformationAndrogel Safety Information
Androgel Safety Information
David Castle
ย 
MLSS Investor Presentation June 2021
MLSS Investor Presentation June 2021MLSS Investor Presentation June 2021
MLSS Investor Presentation June 2021
RedChip Companies, Inc.
ย 
Guidance for industry changes to an approved nda or anda
Guidance for industry changes to an approved nda or andaGuidance for industry changes to an approved nda or anda
Guidance for industry changes to an approved nda or anda
Gaurav Sharma
ย 
Txmd investor presentation.4-16-13
Txmd   investor presentation.4-16-13Txmd   investor presentation.4-16-13
Txmd investor presentation.4-16-13Draco Financial
ย 
Phrmacogentics
PhrmacogenticsPhrmacogentics
Phrmacogentics
Maan Singh
ย 
Opexa therapeutics corporate presentation march 2014
Opexa therapeutics corporate presentation march 2014Opexa therapeutics corporate presentation march 2014
Opexa therapeutics corporate presentation march 2014OpexaTherapeutics
ย 
Supplemental new drug application
Supplemental new drug applicationSupplemental new drug application
Supplemental new drug application
garimasaini33
ย 
Comparative Study of Dossier Compilation & Submission Process of Drug Product...
Comparative Study of Dossier Compilation & Submission Process of Drug Product...Comparative Study of Dossier Compilation & Submission Process of Drug Product...
Comparative Study of Dossier Compilation & Submission Process of Drug Product...
DeveshDRA
ย 
SciTech Development - Pediatric Oncology Focus
SciTech Development - Pediatric Oncology FocusSciTech Development - Pediatric Oncology Focus
SciTech Development - Pediatric Oncology Focus
SciTech Development
ย 
Opexa therapeutics corporate presentation february 2016 web
Opexa therapeutics corporate presentation february 2016 webOpexa therapeutics corporate presentation february 2016 web
Opexa therapeutics corporate presentation february 2016 web
OpexaTherapeutics
ย 
Pharmaceutical Industry
Pharmaceutical IndustryPharmaceutical Industry
Pharmaceutical Industry
Amit Roy
ย 
Types of Pharmaceutical Companies Serving The Pharmaceutical Industry
Types of Pharmaceutical Companies Serving The Pharmaceutical IndustryTypes of Pharmaceutical Companies Serving The Pharmaceutical Industry
Types of Pharmaceutical Companies Serving The Pharmaceutical Industry
Stuart Silverman
ย 
Paper nda
Paper nda Paper nda
Paper nda
Pradeep Gusain
ย 

What's hot (20)

EMERGING APPROACHES TO COMBINATION THERAPIES IN AMD & DME - Regeneron
EMERGING APPROACHES TO COMBINATION THERAPIES IN AMD & DME - RegeneronEMERGING APPROACHES TO COMBINATION THERAPIES IN AMD & DME - Regeneron
EMERGING APPROACHES TO COMBINATION THERAPIES IN AMD & DME - Regeneron
ย 
How to set up a TDM unit dr. Shakeeb Dhorajiwala
How to set up a TDM unit dr. Shakeeb Dhorajiwala How to set up a TDM unit dr. Shakeeb Dhorajiwala
How to set up a TDM unit dr. Shakeeb Dhorajiwala
ย 
Opexa therapeutics corporate presentation june 2014
Opexa therapeutics corporate presentation june 2014Opexa therapeutics corporate presentation june 2014
Opexa therapeutics corporate presentation june 2014
ย 
Opexa therapeutics corporate presentation june 2014 for print
Opexa therapeutics corporate presentation june 2014 for printOpexa therapeutics corporate presentation june 2014 for print
Opexa therapeutics corporate presentation june 2014 for print
ย 
Opexa Therapeutics Corporate Presentation July 2014
Opexa Therapeutics Corporate Presentation July 2014Opexa Therapeutics Corporate Presentation July 2014
Opexa Therapeutics Corporate Presentation July 2014
ย 
Androgel Safety Information
Androgel Safety InformationAndrogel Safety Information
Androgel Safety Information
ย 
MLSS Investor Presentation June 2021
MLSS Investor Presentation June 2021MLSS Investor Presentation June 2021
MLSS Investor Presentation June 2021
ย 
Guidance for industry changes to an approved nda or anda
Guidance for industry changes to an approved nda or andaGuidance for industry changes to an approved nda or anda
Guidance for industry changes to an approved nda or anda
ย 
Txmd investor presentation.4-16-13
Txmd   investor presentation.4-16-13Txmd   investor presentation.4-16-13
Txmd investor presentation.4-16-13
ย 
Qysmia
QysmiaQysmia
Qysmia
ย 
Phrmacogentics
PhrmacogenticsPhrmacogentics
Phrmacogentics
ย 
Opexa therapeutics corporate presentation march 2014
Opexa therapeutics corporate presentation march 2014Opexa therapeutics corporate presentation march 2014
Opexa therapeutics corporate presentation march 2014
ย 
Supplemental new drug application
Supplemental new drug applicationSupplemental new drug application
Supplemental new drug application
ย 
Comparative Study of Dossier Compilation & Submission Process of Drug Product...
Comparative Study of Dossier Compilation & Submission Process of Drug Product...Comparative Study of Dossier Compilation & Submission Process of Drug Product...
Comparative Study of Dossier Compilation & Submission Process of Drug Product...
ย 
SciTech Development - Pediatric Oncology Focus
SciTech Development - Pediatric Oncology FocusSciTech Development - Pediatric Oncology Focus
SciTech Development - Pediatric Oncology Focus
ย 
Opexa therapeutics corporate presentation february 2016 web
Opexa therapeutics corporate presentation february 2016 webOpexa therapeutics corporate presentation february 2016 web
Opexa therapeutics corporate presentation february 2016 web
ย 
Pharmaceutical Industry
Pharmaceutical IndustryPharmaceutical Industry
Pharmaceutical Industry
ย 
Types of Pharmaceutical Companies Serving The Pharmaceutical Industry
Types of Pharmaceutical Companies Serving The Pharmaceutical IndustryTypes of Pharmaceutical Companies Serving The Pharmaceutical Industry
Types of Pharmaceutical Companies Serving The Pharmaceutical Industry
ย 
05 opxa
05 opxa05 opxa
05 opxa
ย 
Paper nda
Paper nda Paper nda
Paper nda
ย 

Similar to Transdel Pharmaceuticals Inc., (TDLP.OB)

Snti 102013
Snti 102013Snti 102013
Snti 102013
RedChip Companies, Inc.
ย 
Urologix, Inc. (ULGX)
Urologix, Inc. (ULGX)Urologix, Inc. (ULGX)
Urologix, Inc. (ULGX)
Brett_Johnson
ย 
Bellus health agm presentation en final
Bellus health agm presentation en   finalBellus health agm presentation en   final
Bellus health agm presentation en final
BellusHealth
ย 
Opexa Therapeutics August 2015 OPXA Corporate Presentation
Opexa Therapeutics August 2015 OPXA Corporate PresentationOpexa Therapeutics August 2015 OPXA Corporate Presentation
Opexa Therapeutics August 2015 OPXA Corporate Presentation
OpexaTherapeutics
ย 
Ophthalmology Innovation Showcase 1 - Ocular Therapeutix
Ophthalmology Innovation Showcase 1 - Ocular TherapeutixOphthalmology Innovation Showcase 1 - Ocular Therapeutix
Ophthalmology Innovation Showcase 1 - Ocular Therapeutix
Healthegy
ย 
Ocular
OcularOcular
Ocular
Healthegy
ย 
Investor presentation july_2011_final
Investor presentation july_2011_finalInvestor presentation july_2011_final
Investor presentation july_2011_final
rymankoly
ย 
IntelGenx Presentation Apr 2018
IntelGenx Presentation Apr 2018IntelGenx Presentation Apr 2018
IntelGenx Presentation Apr 2018
ItelGenx
ย 
Opexa Therapeutics November Corporate Presentation
Opexa Therapeutics November Corporate PresentationOpexa Therapeutics November Corporate Presentation
Opexa Therapeutics November Corporate Presentation
OpexaTherapeutics
ย 
Antares presentation -_september_2013
Antares presentation -_september_2013Antares presentation -_september_2013
Antares presentation -_september_2013
rymankoly
ย 
Investor presentation september_2011_
Investor presentation september_2011_Investor presentation september_2011_
Investor presentation september_2011_
rymankoly
ย 
Research and Development by Bishnu Adhikari
Research and Development by Bishnu AdhikariResearch and Development by Bishnu Adhikari
Research and Development by Bishnu Adhikari
Bishnu Adhikari
ย 
IGX Investor Presentation
IGX Investor PresentationIGX Investor Presentation
IGX Investor Presentation
ItelGenx
ย 
Galena presentation
Galena presentationGalena presentation
Galena presentation
Galenabio
ย 
Bellus health corporate presentation baird conference september 6
Bellus health corporate presentation baird conference   september 6Bellus health corporate presentation baird conference   september 6
Bellus health corporate presentation baird conference september 6
BellusHealth
ย 
Bellus health presentation september 14, 2017
Bellus health presentation   september 14, 2017Bellus health presentation   september 14, 2017
Bellus health presentation september 14, 2017
BellusHealth
ย 
Merck asco-briefing-slides
Merck asco-briefing-slidesMerck asco-briefing-slides
Merck asco-briefing-slides
The ScientifiK
ย 
ARSTAT_Introduction
ARSTAT_IntroductionARSTAT_Introduction
ARSTAT_Introduction
Arkady Rubin
ย 
Bellus health bbhic presentation may 3 st v final
Bellus health bbhic presentation may 3 st v finalBellus health bbhic presentation may 3 st v final
Bellus health bbhic presentation may 3 st v final
BellusHealth
ย 
Clinical Trial Results Transparency and the Changing Paradigm of Medical Comm...
Clinical Trial Results Transparency and the Changing Paradigm of Medical Comm...Clinical Trial Results Transparency and the Changing Paradigm of Medical Comm...
Clinical Trial Results Transparency and the Changing Paradigm of Medical Comm...
ClinTrialsClick
ย 

Similar to Transdel Pharmaceuticals Inc., (TDLP.OB) (20)

Snti 102013
Snti 102013Snti 102013
Snti 102013
ย 
Urologix, Inc. (ULGX)
Urologix, Inc. (ULGX)Urologix, Inc. (ULGX)
Urologix, Inc. (ULGX)
ย 
Bellus health agm presentation en final
Bellus health agm presentation en   finalBellus health agm presentation en   final
Bellus health agm presentation en final
ย 
Opexa Therapeutics August 2015 OPXA Corporate Presentation
Opexa Therapeutics August 2015 OPXA Corporate PresentationOpexa Therapeutics August 2015 OPXA Corporate Presentation
Opexa Therapeutics August 2015 OPXA Corporate Presentation
ย 
Ophthalmology Innovation Showcase 1 - Ocular Therapeutix
Ophthalmology Innovation Showcase 1 - Ocular TherapeutixOphthalmology Innovation Showcase 1 - Ocular Therapeutix
Ophthalmology Innovation Showcase 1 - Ocular Therapeutix
ย 
Ocular
OcularOcular
Ocular
ย 
Investor presentation july_2011_final
Investor presentation july_2011_finalInvestor presentation july_2011_final
Investor presentation july_2011_final
ย 
IntelGenx Presentation Apr 2018
IntelGenx Presentation Apr 2018IntelGenx Presentation Apr 2018
IntelGenx Presentation Apr 2018
ย 
Opexa Therapeutics November Corporate Presentation
Opexa Therapeutics November Corporate PresentationOpexa Therapeutics November Corporate Presentation
Opexa Therapeutics November Corporate Presentation
ย 
Antares presentation -_september_2013
Antares presentation -_september_2013Antares presentation -_september_2013
Antares presentation -_september_2013
ย 
Investor presentation september_2011_
Investor presentation september_2011_Investor presentation september_2011_
Investor presentation september_2011_
ย 
Research and Development by Bishnu Adhikari
Research and Development by Bishnu AdhikariResearch and Development by Bishnu Adhikari
Research and Development by Bishnu Adhikari
ย 
IGX Investor Presentation
IGX Investor PresentationIGX Investor Presentation
IGX Investor Presentation
ย 
Galena presentation
Galena presentationGalena presentation
Galena presentation
ย 
Bellus health corporate presentation baird conference september 6
Bellus health corporate presentation baird conference   september 6Bellus health corporate presentation baird conference   september 6
Bellus health corporate presentation baird conference september 6
ย 
Bellus health presentation september 14, 2017
Bellus health presentation   september 14, 2017Bellus health presentation   september 14, 2017
Bellus health presentation september 14, 2017
ย 
Merck asco-briefing-slides
Merck asco-briefing-slidesMerck asco-briefing-slides
Merck asco-briefing-slides
ย 
ARSTAT_Introduction
ARSTAT_IntroductionARSTAT_Introduction
ARSTAT_Introduction
ย 
Bellus health bbhic presentation may 3 st v final
Bellus health bbhic presentation may 3 st v finalBellus health bbhic presentation may 3 st v final
Bellus health bbhic presentation may 3 st v final
ย 
Clinical Trial Results Transparency and the Changing Paradigm of Medical Comm...
Clinical Trial Results Transparency and the Changing Paradigm of Medical Comm...Clinical Trial Results Transparency and the Changing Paradigm of Medical Comm...
Clinical Trial Results Transparency and the Changing Paradigm of Medical Comm...
ย 

Recently uploaded

Business Valuation Principles for Entrepreneurs
Business Valuation Principles for EntrepreneursBusiness Valuation Principles for Entrepreneurs
Business Valuation Principles for Entrepreneurs
Ben Wann
ย 
Improving profitability for small business
Improving profitability for small businessImproving profitability for small business
Improving profitability for small business
Ben Wann
ย 
What are the main advantages of using HR recruiter services.pdf
What are the main advantages of using HR recruiter services.pdfWhat are the main advantages of using HR recruiter services.pdf
What are the main advantages of using HR recruiter services.pdf
HumanResourceDimensi1
ย 
The-McKinsey-7S-Framework. strategic management
The-McKinsey-7S-Framework. strategic managementThe-McKinsey-7S-Framework. strategic management
The-McKinsey-7S-Framework. strategic management
Bojamma2
ย 
FINAL PRESENTATION.pptx12143241324134134
FINAL PRESENTATION.pptx12143241324134134FINAL PRESENTATION.pptx12143241324134134
FINAL PRESENTATION.pptx12143241324134134
LR1709MUSIC
ย 
20240425_ TJ Communications Credentials_compressed.pdf
20240425_ TJ Communications Credentials_compressed.pdf20240425_ TJ Communications Credentials_compressed.pdf
20240425_ TJ Communications Credentials_compressed.pdf
tjcomstrang
ย 
Sustainability: Balancing the Environment, Equity & Economy
Sustainability: Balancing the Environment, Equity & EconomySustainability: Balancing the Environment, Equity & Economy
Sustainability: Balancing the Environment, Equity & Economy
Operational Excellence Consulting
ย 
anas about venice for grade 6f about venice
anas about venice for grade 6f about veniceanas about venice for grade 6f about venice
anas about venice for grade 6f about venice
anasabutalha2013
ย 
falcon-invoice-discounting-a-premier-platform-for-investors-in-india
falcon-invoice-discounting-a-premier-platform-for-investors-in-indiafalcon-invoice-discounting-a-premier-platform-for-investors-in-india
falcon-invoice-discounting-a-premier-platform-for-investors-in-india
Falcon Invoice Discounting
ย 
Attending a job Interview for B1 and B2 Englsih learners
Attending a job Interview for B1 and B2 Englsih learnersAttending a job Interview for B1 and B2 Englsih learners
Attending a job Interview for B1 and B2 Englsih learners
Erika906060
ย 
ikea_woodgreen_petscharity_dog-alogue_digital.pdf
ikea_woodgreen_petscharity_dog-alogue_digital.pdfikea_woodgreen_petscharity_dog-alogue_digital.pdf
ikea_woodgreen_petscharity_dog-alogue_digital.pdf
agatadrynko
ย 
Kseniya Leshchenko: Shared development support service model as the way to ma...
Kseniya Leshchenko: Shared development support service model as the way to ma...Kseniya Leshchenko: Shared development support service model as the way to ma...
Kseniya Leshchenko: Shared development support service model as the way to ma...
Lviv Startup Club
ย 
The Influence of Marketing Strategy and Market Competition on Business Perfor...
The Influence of Marketing Strategy and Market Competition on Business Perfor...The Influence of Marketing Strategy and Market Competition on Business Perfor...
The Influence of Marketing Strategy and Market Competition on Business Perfor...
Adam Smith
ย 
Unveiling the Secrets How Does Generative AI Work.pdf
Unveiling the Secrets How Does Generative AI Work.pdfUnveiling the Secrets How Does Generative AI Work.pdf
Unveiling the Secrets How Does Generative AI Work.pdf
Sam H
ย 
Search Disrupted Googleโ€™s Leaked Documents Rock the SEO World.pdf
Search Disrupted Googleโ€™s Leaked Documents Rock the SEO World.pdfSearch Disrupted Googleโ€™s Leaked Documents Rock the SEO World.pdf
Search Disrupted Googleโ€™s Leaked Documents Rock the SEO World.pdf
Arihant Webtech Pvt. Ltd
ย 
Cracking the Workplace Discipline Code Main.pptx
Cracking the Workplace Discipline Code Main.pptxCracking the Workplace Discipline Code Main.pptx
Cracking the Workplace Discipline Code Main.pptx
Workforce Group
ย 
ENTREPRENEURSHIP TRAINING.ppt for graduating class (1).ppt
ENTREPRENEURSHIP TRAINING.ppt for graduating class (1).pptENTREPRENEURSHIP TRAINING.ppt for graduating class (1).ppt
ENTREPRENEURSHIP TRAINING.ppt for graduating class (1).ppt
zechu97
ย 
5 Things You Need To Know Before Hiring a Videographer
5 Things You Need To Know Before Hiring a Videographer5 Things You Need To Know Before Hiring a Videographer
5 Things You Need To Know Before Hiring a Videographer
ofm712785
ย 
Enterprise Excellence is Inclusive Excellence.pdf
Enterprise Excellence is Inclusive Excellence.pdfEnterprise Excellence is Inclusive Excellence.pdf
Enterprise Excellence is Inclusive Excellence.pdf
KaiNexus
ย 
Digital Transformation and IT Strategy Toolkit and Templates
Digital Transformation and IT Strategy Toolkit and TemplatesDigital Transformation and IT Strategy Toolkit and Templates
Digital Transformation and IT Strategy Toolkit and Templates
Aurelien Domont, MBA
ย 

Recently uploaded (20)

Business Valuation Principles for Entrepreneurs
Business Valuation Principles for EntrepreneursBusiness Valuation Principles for Entrepreneurs
Business Valuation Principles for Entrepreneurs
ย 
Improving profitability for small business
Improving profitability for small businessImproving profitability for small business
Improving profitability for small business
ย 
What are the main advantages of using HR recruiter services.pdf
What are the main advantages of using HR recruiter services.pdfWhat are the main advantages of using HR recruiter services.pdf
What are the main advantages of using HR recruiter services.pdf
ย 
The-McKinsey-7S-Framework. strategic management
The-McKinsey-7S-Framework. strategic managementThe-McKinsey-7S-Framework. strategic management
The-McKinsey-7S-Framework. strategic management
ย 
FINAL PRESENTATION.pptx12143241324134134
FINAL PRESENTATION.pptx12143241324134134FINAL PRESENTATION.pptx12143241324134134
FINAL PRESENTATION.pptx12143241324134134
ย 
20240425_ TJ Communications Credentials_compressed.pdf
20240425_ TJ Communications Credentials_compressed.pdf20240425_ TJ Communications Credentials_compressed.pdf
20240425_ TJ Communications Credentials_compressed.pdf
ย 
Sustainability: Balancing the Environment, Equity & Economy
Sustainability: Balancing the Environment, Equity & EconomySustainability: Balancing the Environment, Equity & Economy
Sustainability: Balancing the Environment, Equity & Economy
ย 
anas about venice for grade 6f about venice
anas about venice for grade 6f about veniceanas about venice for grade 6f about venice
anas about venice for grade 6f about venice
ย 
falcon-invoice-discounting-a-premier-platform-for-investors-in-india
falcon-invoice-discounting-a-premier-platform-for-investors-in-indiafalcon-invoice-discounting-a-premier-platform-for-investors-in-india
falcon-invoice-discounting-a-premier-platform-for-investors-in-india
ย 
Attending a job Interview for B1 and B2 Englsih learners
Attending a job Interview for B1 and B2 Englsih learnersAttending a job Interview for B1 and B2 Englsih learners
Attending a job Interview for B1 and B2 Englsih learners
ย 
ikea_woodgreen_petscharity_dog-alogue_digital.pdf
ikea_woodgreen_petscharity_dog-alogue_digital.pdfikea_woodgreen_petscharity_dog-alogue_digital.pdf
ikea_woodgreen_petscharity_dog-alogue_digital.pdf
ย 
Kseniya Leshchenko: Shared development support service model as the way to ma...
Kseniya Leshchenko: Shared development support service model as the way to ma...Kseniya Leshchenko: Shared development support service model as the way to ma...
Kseniya Leshchenko: Shared development support service model as the way to ma...
ย 
The Influence of Marketing Strategy and Market Competition on Business Perfor...
The Influence of Marketing Strategy and Market Competition on Business Perfor...The Influence of Marketing Strategy and Market Competition on Business Perfor...
The Influence of Marketing Strategy and Market Competition on Business Perfor...
ย 
Unveiling the Secrets How Does Generative AI Work.pdf
Unveiling the Secrets How Does Generative AI Work.pdfUnveiling the Secrets How Does Generative AI Work.pdf
Unveiling the Secrets How Does Generative AI Work.pdf
ย 
Search Disrupted Googleโ€™s Leaked Documents Rock the SEO World.pdf
Search Disrupted Googleโ€™s Leaked Documents Rock the SEO World.pdfSearch Disrupted Googleโ€™s Leaked Documents Rock the SEO World.pdf
Search Disrupted Googleโ€™s Leaked Documents Rock the SEO World.pdf
ย 
Cracking the Workplace Discipline Code Main.pptx
Cracking the Workplace Discipline Code Main.pptxCracking the Workplace Discipline Code Main.pptx
Cracking the Workplace Discipline Code Main.pptx
ย 
ENTREPRENEURSHIP TRAINING.ppt for graduating class (1).ppt
ENTREPRENEURSHIP TRAINING.ppt for graduating class (1).pptENTREPRENEURSHIP TRAINING.ppt for graduating class (1).ppt
ENTREPRENEURSHIP TRAINING.ppt for graduating class (1).ppt
ย 
5 Things You Need To Know Before Hiring a Videographer
5 Things You Need To Know Before Hiring a Videographer5 Things You Need To Know Before Hiring a Videographer
5 Things You Need To Know Before Hiring a Videographer
ย 
Enterprise Excellence is Inclusive Excellence.pdf
Enterprise Excellence is Inclusive Excellence.pdfEnterprise Excellence is Inclusive Excellence.pdf
Enterprise Excellence is Inclusive Excellence.pdf
ย 
Digital Transformation and IT Strategy Toolkit and Templates
Digital Transformation and IT Strategy Toolkit and TemplatesDigital Transformation and IT Strategy Toolkit and Templates
Digital Transformation and IT Strategy Toolkit and Templates
ย 

Transdel Pharmaceuticals Inc., (TDLP.OB)

  • 1.
  • 2.
  • 3.
  • 4.
  • 5.
  • 6. Selected Pipeline *TDB โ€“ To Be Determined Program Target Status Partner(s) Launch Date Ketotransdel Pain (NSAID) Phase III TBD* TDLP310 Cellulite Subject Trials JH Direct & Jan Marini Skin Research Anticipate 2010 TDLP320 Anti-Aging Formulation TBD* TDLP330 Pigmentation Formulation TBD*
  • 7.
  • 8.
  • 9. Clinical Design: Randomized, double-blind, placebo-controlled Study Population: Patients with acute soft tissue injuries (sprains & strains) Indication: Relief of pain from acute soft tissue injuries Dosing Regimen: Ketotransdel vs. Placebo (Vehicle) cream, 1g three times daily over 7 days Primary Endpoint: Change from baseline in pain intensity on Day 3 Visit (+1, +2 days) with VAS measurement Secondary Endpoints: Safety assessments, various other efficacy variables Pharmacokinetics in subset of patients Clinical Sites: 26 (USA) Randomized: N=364 Ketotransdel Phase 3 Trial
  • 10. Ketotransdel demonstrated statistically significant higher reduction in pain intensity from baseline in both the modified Intent-To-Treat (ITT) and Per Protocol (PP) analysis. PP (n=252) mITT (n=326) Mean reduction from baseline in mm (100 mm Visual Analogue Scale) mm Reduction in Pain Intensity from baseline on Day 3 Ketotransdel Phase 3 Trial TDLP-110-001: Primary Efficacy Endpoint Results * p < 0.05 * p = 0.038 * A nalysis of all ITT patients who met study entry criteria , ANCOVA on change from baseline in pain intensity during daily activities over the past 24 hours on Day 3 Visit (Day 3, +1 or +2 days)
  • 11. Ketotransdel Phase 3 Trial TDLP-110-001: Efficacy Endpoint: Change from baseline in three-times-daily pain intensity The Pain Curves over time show consistent separation between treatment groups reaching statistical significance in favor of Ketotransdel in ITT analyses . * Time period that primary endpoint โ€œDay 3 Visitโ€ covers: Days 3, 4 and 5. * Ketotransdel Placebo
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17. Competitive Landscape FDA Approved Topical NSAIDs Product Indication Dosage Company Flector Patch 1.3% diclofenac Acute Pain (strains & sprains) 10 x 14 cm patch, 2 times per day King Pharma/ IBSA Voltaren Gel 1% diclofenac Osteoarthritis knee/ hands 2- 4 g qid (16g/d) ENDO/ Novartis Pennsaid 1.5% diclofenac Osteoarthritis knee 40 drops of liquid (10 drops to each of 4 sides of knee), 3-4 times per day Covidien/ NUVO
  • 18.
  • 19.
  • 20. Select Financials Key Statistics Symbol: TDLP.OB Fiscal Year End: December 31 st Current Price (6/17/10): $1.20 Shares Outstanding: 15.7 million Market Cap: $19 million Proforma cash (as of 3/31/10) (1) $2.0 million ( 1) Includes $1M proceeds from convertible senior promissory note issued in April 2010.
  • 21. Contact Us Transdel Pharmaceuticals, Inc . (OTC BB: TDLP.OB) 4225 Executive Square Suite 485 La Jolla, CA 92037 Corporate Headquarters Investor Contact John Lomoro Chief Financial Officer and Acting Chief Executive Officer (858) 457-5300 [email_address] Please visit www.transdelpharma.com for more information.