Antibodies for commonly mutated targets
https://www.antibody-creativebiolabs.com/symbolsearch-tp53.htm
Innovative technologies and ideas
Numerous worldwide customers
High-level Ph.D. scientists and experienced technicians
High efficiency and short turnaround time
Close collaboration
Extensive forefront knowledge sharing
Advanced and one-stop platforms
Ctnnb1 antibody for hepatocellular carcinomaEchoHan4
CTNNB1
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. https://www.antibody-creativebiolabs.com/symbolsearch-ctnnb1.htm
BRAF
This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. https://www.antibody-creativebiolabs.com/symbolsearch-braf.htm
Flt3 antibody antibodies for hematologic malignanciesCreative Biolabs
Hematologic malignancies, also known as cancer of the blood or lymph system, are classified as three main types including leukemia, lymphoma and myeloma. www.antibody-creativebiolabs.com
CD96 antibody for t cell co signaling researchEchoHan4
This document from Creative Biolabs promotes their antibodies for research on T cell co-signaling. It provides an overview of T cell co-signaling and lists many antibodies they offer against co-stimulatory and co-inhibitory molecules from the Ig superfamily, TNF superfamily, and other families involved in T cell activation. The antibodies listed come from mouse, human and other species and are suitable for applications like flow cytometry, immunohistochemistry and western blotting to facilitate research on T cell co-signaling pathways.
Anti gfap antibodies for neuroscience research creative biolabsCreative Biolabs
The human brain remains a great mystery in science and current research
strives to understand molecular and cellular processes of the nervous
system. The prevention and effective treatment of neurological disorders
like Alzheimer's and Parkinson's diseases has been a major medical
challenge. Creative Biolabs offers a broad range of antibodies to help you
win the race in your discovery of the nervous system. www.antibody-creativebiolabs.com
This document discusses the results of a BLASTx search of a DNA sequence from an operon gum between 21,000-23,000 base pairs. The top hit was to the GumC protein in Xanthomonas campestris with an E-value of 1.2e-116. Other significant hits included the GumD protein in X. campestris and proteins involved in exopolysaccharide biosynthesis and transport in organisms like Rhizobium meliloti. The BLASTx results indicate homology between the query sequence and proteins involved in gum biosynthesis.
43 elisa kits for esophageal carcinoma researchElabscience
Esophageal carcinoma (or oesophageal cancer) is cancer arising from the esophagus—the food pipe that runs between the throat and the stomach. Symptoms often include difficulty in swallowing and weight loss. Other symptoms may include pain when swallowing, a hoarse voice,enlarged lymph nodes (glands) around the collarbone, a dry cough, and possibly coughing up or vomiting blood.More info visit: http://www.elabscience.com
A bone tumor, (also spelled bone tumour), is a neoplastic growth of tissue in bone. The most common symptom of bone tumors is pain, which will gradually increase over time. Additional symptoms may include fatigue, fever, weight loss, anemia, and/or unexplained bone fractures. More info visit: http://www.elabscience.com
Ctnnb1 antibody for hepatocellular carcinomaEchoHan4
CTNNB1
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. https://www.antibody-creativebiolabs.com/symbolsearch-ctnnb1.htm
BRAF
This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. https://www.antibody-creativebiolabs.com/symbolsearch-braf.htm
Flt3 antibody antibodies for hematologic malignanciesCreative Biolabs
Hematologic malignancies, also known as cancer of the blood or lymph system, are classified as three main types including leukemia, lymphoma and myeloma. www.antibody-creativebiolabs.com
CD96 antibody for t cell co signaling researchEchoHan4
This document from Creative Biolabs promotes their antibodies for research on T cell co-signaling. It provides an overview of T cell co-signaling and lists many antibodies they offer against co-stimulatory and co-inhibitory molecules from the Ig superfamily, TNF superfamily, and other families involved in T cell activation. The antibodies listed come from mouse, human and other species and are suitable for applications like flow cytometry, immunohistochemistry and western blotting to facilitate research on T cell co-signaling pathways.
Anti gfap antibodies for neuroscience research creative biolabsCreative Biolabs
The human brain remains a great mystery in science and current research
strives to understand molecular and cellular processes of the nervous
system. The prevention and effective treatment of neurological disorders
like Alzheimer's and Parkinson's diseases has been a major medical
challenge. Creative Biolabs offers a broad range of antibodies to help you
win the race in your discovery of the nervous system. www.antibody-creativebiolabs.com
This document discusses the results of a BLASTx search of a DNA sequence from an operon gum between 21,000-23,000 base pairs. The top hit was to the GumC protein in Xanthomonas campestris with an E-value of 1.2e-116. Other significant hits included the GumD protein in X. campestris and proteins involved in exopolysaccharide biosynthesis and transport in organisms like Rhizobium meliloti. The BLASTx results indicate homology between the query sequence and proteins involved in gum biosynthesis.
43 elisa kits for esophageal carcinoma researchElabscience
Esophageal carcinoma (or oesophageal cancer) is cancer arising from the esophagus—the food pipe that runs between the throat and the stomach. Symptoms often include difficulty in swallowing and weight loss. Other symptoms may include pain when swallowing, a hoarse voice,enlarged lymph nodes (glands) around the collarbone, a dry cough, and possibly coughing up or vomiting blood.More info visit: http://www.elabscience.com
A bone tumor, (also spelled bone tumour), is a neoplastic growth of tissue in bone. The most common symptom of bone tumors is pain, which will gradually increase over time. Additional symptoms may include fatigue, fever, weight loss, anemia, and/or unexplained bone fractures. More info visit: http://www.elabscience.com
09 elisa kits for hemangioma of bone researchElabscience
Hemagioma can occurs in all parts of the body, and it may also occurs
in bone, but the latter is more rare than the others parts of body.
Hemangioma of bone sometimes exists with hemangioma of other parts at
the same time, it is a common tumor of benign tumor attached in bone
tissue.More info visit: http://www.elabscience.com
52 elisa kits for nasopharynx cancer researchElabscience
Nasopharynx cancer or nasopharyngeal carcinoma (NPC) is the most common cancer originating in the nasopharynx, the uppermost region of the pharynx ("throat"), behind the nose where thenasal passages and auditory tubes join the remainder of the upper respiratory tract. Nasopharyngeal carcinoma (NPC) is caused by a combination of factors: viral, environmental influences, and heredity.More info visit: http://www.elabscience.com
Elisa kits for hand foot and mouth disease researchElabscience
Hand, foot and mouth disease (HFMD) is a common infection caused by a group of viruses. which are spread through close personal contact, through the air from coughing, and the feces of an infected person. Contaminated objects can also spread the disease. More info visit: http://www.elabscience.com
Global warming and the Jellyfish toxidromeCoda Change
From #CodaZero Live, Alice Young provides a brief update on the presentation, complications and management of Irukandji syndrome; and why we all need to know about it.
This document describes immunohistochemistry staining of mouse brain tissue to label various proteins. It includes details on primary and secondary antibodies used to stain for glial fibrillary acidic protein (GFAP) in astrocytes of the hippocampus and aquaporin 1 and 4 (AQP1, AQP4) in the choroid plexus and ventricles. References are provided on the role of aquaporins and the choroid plexus in cerebrospinal fluid production and homeostasis. Future work proposed includes RNA sequencing of choroid plexus from LXRβ knockout and wild type mice.
In mammals, there are two broad types of stem cells: embryonic stem cells, which are isolated from the inner cell mass of blastocysts, and adult stem cells, which are found in
various tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing adult tissues. Elabscience provides 700+ antibodies for stem cells research. Worth to check!
More other antibodies:
http://www.elabscience.com/index.php/product/show/tid/73
50 elisa kits for maxillary sinus carcinoma researchElabscience
This document lists various ELISA kits produced by Elabscience for detecting levels of proteins involved in cancer. It provides the product name, detection range, sensitivity, and test method for each kit, which are designed to detect proteins like TP53, CTNNB1, SHH, FGFR3, TP63, BRCA1, BRCA2, IFN-γ, CDKN1A, and others relevant to cancer signaling pathways and development. The kits use a sandwich ELISA method and are able to detect picogram to nanogram per milliliter levels of the target proteins with sensitivities in the picogram to nanogram per milliliter range.
Melanoma, the deadliest skin cancers, is caused by
the transformation of melanocytes which accumulate genetic alterations, leading to abnormal proliferation and dissemination. www.antibody-creativebiolabs.com
Hepatocellular carcinoma (HCC), with a prevalence of around 600,000 people worldwide, is the sixth most common cancer globally. www.antibody-creativebiolabs.com
T cell activation requires two signals. One is recognition of the antigenic peptide/major histocompatibility complex (MHC) by the T cell receptor (TCR); another is antigen independent co-stimulation induced by interactions between co-signaling molecules expressed on antigen-presenting cells (APCs) and their T cell-expressed receptors. www.antibody-creativebiolabs.com
This document provides information on antibodies for breast cancer research from Creative Biolabs. It discusses the types and prevalence of breast cancer and key markers. It then provides a table listing antibodies for commonly mutated targets in breast cancer research, including targets, clone, applications and species reactivity. The document also discusses popular antibodies for other key markers and signaling factors involved in breast cancer.
Breast cancer is the principle cause of cancer-related mortality
among women worldwide. It's highly heterogeneous and can be
classified into 3 types - TNBC, HER2+ and Luminal (non-HER2+). www.antibody-creativebiolabs.com
Secondary antibodies bind to the primary antibody to assist in detection, classification and isolation of interest antigen. To ensure detection, the secondary antibody must be specific for the isotype and antibody species of the primary antibody in the application. Secondary antibodies are typically polyclonal.
Secondary antibody conjugates are important tools in biochemical and cell-based analysis. Enzyme-labeled secondary antibodies have high catalytic turnover rates and are routinely used in various assays for their robust and rapid signal generation. Secondary antibodies conjugated to fluorescent dyes offer brighter signals and multiplexing capabilities in cell analysis and protein analysis applications including immunofluorescence microscopy and cell imaging. For both enzyme-labeled and dye-labeled secondary antibodies, high sensitivity and signal amplification are two desirable qualities when detecting target antigens of low abundance.
The human brain remains a great mystery in science and current research strives to understand molecular and cellular processes of the nervous system.https://www.antibody-creativebiolabs.com/search.aspx?key=neuroscience&ty=tag
Antibody arrays have emerged as an important tool, which enable multiplexed protein expression profiling such as cytokines, chemokines and growth factors, which may be involved in diseases. To design high-performing antibody arrays, it is necessary to develop an integrated technology platform, where the interplay between the surfaces and the antibody is anticipated to play an important role.
https://www.antibody-creativebiolabs.com/category/glass-slide-antibody-arrays-126.htm
The document discusses immunotherapy and immunological checkpoint treatment. It provides background on how immunotherapy works to activate the immune system against tumors. Immunological checkpoint treatment in particular has shown promise, with FDA approval of antibodies against CTLA-4 and PD-1. Ongoing research is exploring additional immunosuppressive targets like LAG-3, TIM-3, and TIGIT. The document also lists antibodies available from Creative Biolabs that target checkpoints like CTLA-4, PD-1, and IL-17A for research purposes.
Creative Biolabs offers a comprehensive range of quality recombinant antibodies for cell & organelle imaging. These antibodies are covering significant research areas such as cancer research, cell signaling, cell morphology and organelle detection.
Live cell imaging is the study of living cells using time-lapse microscopy. Scientists use it to better understand and validate the biological function through the study of cellular dynamics. Organelles are specialized and well-defined parts of the cell which are usually separately enclosed within their own lipid bilayers. Very often organelles have to be stained to follow cellular processes and the effects of changing parameters on these processes. Thus, there is a great significance and strong need for tools to stain and follow specific organelles in living cells.
https://www.antibody-creativebiolabs.com/category-introduction/cell-organelle-imaging-3.htm
Neuroscience is the scientific study of the nervous system. The scope of neuroscience has broadened to include different approaches used to study the molecular, cellular, developmental, structural, functional, evolutionary, computational, and medical aspects of the nervous system. Elabscience offers 380+ antibodies for your neuroscience research.
Click for more antibodies:
http://www.elabscience.com/index.php/product/show/tid/90
Robert Soler and Lluis Orozco. Regenerative Tissue Therapy Institute at the T...MuscleTech Network
This document discusses research on stem cell therapy. It references animal models using cartilage from sheep and horses, as well as tendons from horses. Clinical trials are mentioned for using stem cells to treat pseudoarthrosis, bone injuries, osteonecrosis, and cartilage defects of varying severity. Regulations and guidelines from the EMA, PEI, and Spanish laws are covered. Applications discussed include muscle repair timing, stem cell differentiation potential, and clinical trials for rotator cuff injuries and epicondylitis using doses of MSCs ranging from 1-40 million. The conclusion emphasizes that stem cell therapy with MSCs is a viable, safe option showing efficacy indications but currently only available under clinical trials or compassionate use.
Elabscience Biotechnology Inc. specializes in immunodiagnostic technology for life science research. They have a complete R&D and manufacturing platform to produce proteins, antibodies, ELISA kits, and other reagents. Their products are used in applications like ELISA, western blot, immunohistochemistry, and they also offer custom services like protein expression and purification. The document then provides tables listing many of their angiogenesis-related products including various matrix metalloproteinases, integrins, laminins and their targets.
Beta LifeScience Recombinant Protein Catalog.pdfBetaLifeScience
Beta Life Science is a biotech company committed to providing premium quality life science research products and services worldwide emphasizing on a strong portfolio of recombinant proteins, viral antigens, antibodies, and small molecules and ELISA kits.
09 elisa kits for hemangioma of bone researchElabscience
Hemagioma can occurs in all parts of the body, and it may also occurs
in bone, but the latter is more rare than the others parts of body.
Hemangioma of bone sometimes exists with hemangioma of other parts at
the same time, it is a common tumor of benign tumor attached in bone
tissue.More info visit: http://www.elabscience.com
52 elisa kits for nasopharynx cancer researchElabscience
Nasopharynx cancer or nasopharyngeal carcinoma (NPC) is the most common cancer originating in the nasopharynx, the uppermost region of the pharynx ("throat"), behind the nose where thenasal passages and auditory tubes join the remainder of the upper respiratory tract. Nasopharyngeal carcinoma (NPC) is caused by a combination of factors: viral, environmental influences, and heredity.More info visit: http://www.elabscience.com
Elisa kits for hand foot and mouth disease researchElabscience
Hand, foot and mouth disease (HFMD) is a common infection caused by a group of viruses. which are spread through close personal contact, through the air from coughing, and the feces of an infected person. Contaminated objects can also spread the disease. More info visit: http://www.elabscience.com
Global warming and the Jellyfish toxidromeCoda Change
From #CodaZero Live, Alice Young provides a brief update on the presentation, complications and management of Irukandji syndrome; and why we all need to know about it.
This document describes immunohistochemistry staining of mouse brain tissue to label various proteins. It includes details on primary and secondary antibodies used to stain for glial fibrillary acidic protein (GFAP) in astrocytes of the hippocampus and aquaporin 1 and 4 (AQP1, AQP4) in the choroid plexus and ventricles. References are provided on the role of aquaporins and the choroid plexus in cerebrospinal fluid production and homeostasis. Future work proposed includes RNA sequencing of choroid plexus from LXRβ knockout and wild type mice.
In mammals, there are two broad types of stem cells: embryonic stem cells, which are isolated from the inner cell mass of blastocysts, and adult stem cells, which are found in
various tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing adult tissues. Elabscience provides 700+ antibodies for stem cells research. Worth to check!
More other antibodies:
http://www.elabscience.com/index.php/product/show/tid/73
50 elisa kits for maxillary sinus carcinoma researchElabscience
This document lists various ELISA kits produced by Elabscience for detecting levels of proteins involved in cancer. It provides the product name, detection range, sensitivity, and test method for each kit, which are designed to detect proteins like TP53, CTNNB1, SHH, FGFR3, TP63, BRCA1, BRCA2, IFN-γ, CDKN1A, and others relevant to cancer signaling pathways and development. The kits use a sandwich ELISA method and are able to detect picogram to nanogram per milliliter levels of the target proteins with sensitivities in the picogram to nanogram per milliliter range.
Melanoma, the deadliest skin cancers, is caused by
the transformation of melanocytes which accumulate genetic alterations, leading to abnormal proliferation and dissemination. www.antibody-creativebiolabs.com
Hepatocellular carcinoma (HCC), with a prevalence of around 600,000 people worldwide, is the sixth most common cancer globally. www.antibody-creativebiolabs.com
T cell activation requires two signals. One is recognition of the antigenic peptide/major histocompatibility complex (MHC) by the T cell receptor (TCR); another is antigen independent co-stimulation induced by interactions between co-signaling molecules expressed on antigen-presenting cells (APCs) and their T cell-expressed receptors. www.antibody-creativebiolabs.com
This document provides information on antibodies for breast cancer research from Creative Biolabs. It discusses the types and prevalence of breast cancer and key markers. It then provides a table listing antibodies for commonly mutated targets in breast cancer research, including targets, clone, applications and species reactivity. The document also discusses popular antibodies for other key markers and signaling factors involved in breast cancer.
Breast cancer is the principle cause of cancer-related mortality
among women worldwide. It's highly heterogeneous and can be
classified into 3 types - TNBC, HER2+ and Luminal (non-HER2+). www.antibody-creativebiolabs.com
Secondary antibodies bind to the primary antibody to assist in detection, classification and isolation of interest antigen. To ensure detection, the secondary antibody must be specific for the isotype and antibody species of the primary antibody in the application. Secondary antibodies are typically polyclonal.
Secondary antibody conjugates are important tools in biochemical and cell-based analysis. Enzyme-labeled secondary antibodies have high catalytic turnover rates and are routinely used in various assays for their robust and rapid signal generation. Secondary antibodies conjugated to fluorescent dyes offer brighter signals and multiplexing capabilities in cell analysis and protein analysis applications including immunofluorescence microscopy and cell imaging. For both enzyme-labeled and dye-labeled secondary antibodies, high sensitivity and signal amplification are two desirable qualities when detecting target antigens of low abundance.
The human brain remains a great mystery in science and current research strives to understand molecular and cellular processes of the nervous system.https://www.antibody-creativebiolabs.com/search.aspx?key=neuroscience&ty=tag
Antibody arrays have emerged as an important tool, which enable multiplexed protein expression profiling such as cytokines, chemokines and growth factors, which may be involved in diseases. To design high-performing antibody arrays, it is necessary to develop an integrated technology platform, where the interplay between the surfaces and the antibody is anticipated to play an important role.
https://www.antibody-creativebiolabs.com/category/glass-slide-antibody-arrays-126.htm
The document discusses immunotherapy and immunological checkpoint treatment. It provides background on how immunotherapy works to activate the immune system against tumors. Immunological checkpoint treatment in particular has shown promise, with FDA approval of antibodies against CTLA-4 and PD-1. Ongoing research is exploring additional immunosuppressive targets like LAG-3, TIM-3, and TIGIT. The document also lists antibodies available from Creative Biolabs that target checkpoints like CTLA-4, PD-1, and IL-17A for research purposes.
Creative Biolabs offers a comprehensive range of quality recombinant antibodies for cell & organelle imaging. These antibodies are covering significant research areas such as cancer research, cell signaling, cell morphology and organelle detection.
Live cell imaging is the study of living cells using time-lapse microscopy. Scientists use it to better understand and validate the biological function through the study of cellular dynamics. Organelles are specialized and well-defined parts of the cell which are usually separately enclosed within their own lipid bilayers. Very often organelles have to be stained to follow cellular processes and the effects of changing parameters on these processes. Thus, there is a great significance and strong need for tools to stain and follow specific organelles in living cells.
https://www.antibody-creativebiolabs.com/category-introduction/cell-organelle-imaging-3.htm
Neuroscience is the scientific study of the nervous system. The scope of neuroscience has broadened to include different approaches used to study the molecular, cellular, developmental, structural, functional, evolutionary, computational, and medical aspects of the nervous system. Elabscience offers 380+ antibodies for your neuroscience research.
Click for more antibodies:
http://www.elabscience.com/index.php/product/show/tid/90
Robert Soler and Lluis Orozco. Regenerative Tissue Therapy Institute at the T...MuscleTech Network
This document discusses research on stem cell therapy. It references animal models using cartilage from sheep and horses, as well as tendons from horses. Clinical trials are mentioned for using stem cells to treat pseudoarthrosis, bone injuries, osteonecrosis, and cartilage defects of varying severity. Regulations and guidelines from the EMA, PEI, and Spanish laws are covered. Applications discussed include muscle repair timing, stem cell differentiation potential, and clinical trials for rotator cuff injuries and epicondylitis using doses of MSCs ranging from 1-40 million. The conclusion emphasizes that stem cell therapy with MSCs is a viable, safe option showing efficacy indications but currently only available under clinical trials or compassionate use.
Elabscience Biotechnology Inc. specializes in immunodiagnostic technology for life science research. They have a complete R&D and manufacturing platform to produce proteins, antibodies, ELISA kits, and other reagents. Their products are used in applications like ELISA, western blot, immunohistochemistry, and they also offer custom services like protein expression and purification. The document then provides tables listing many of their angiogenesis-related products including various matrix metalloproteinases, integrins, laminins and their targets.
Beta LifeScience Recombinant Protein Catalog.pdfBetaLifeScience
Beta Life Science is a biotech company committed to providing premium quality life science research products and services worldwide emphasizing on a strong portfolio of recombinant proteins, viral antigens, antibodies, and small molecules and ELISA kits.
Traditional polyclonal antibody preparations are derived from antisera or immunoglobulin preparations from immunized animals. Monoclonal antibodies are produced from immortalized B cells that secrete antibodies against a single epitope. Antibody screening uses phage display technology to identify antibodies that bind to a unique cell surface antigen. Vaccines work by stimulating either active or passive immunity. Active immunity is stimulated through attenuated live vaccines, killed vaccines, or purified vaccine components that trigger an immune response through antigen presentation without causing disease.
Cancer Research Antibodies - ElabscienceElabscience
Cancer is a group of diseases involving abnormal cell growth with thepotential to invade or spread to other parts of the body. Not all tumorsare cancerous; benign tumors do not spread to other parts of the body.Possible signs and symptoms include a lump, abnormal bleeding,prolonged cough, unexplained weight loss and a change in bowelmovements. While these symptoms may indicate cancer, they mayhave other causes.Over 100 cancers affect humans. Elabsciece has 690+ antibodies for cancer research. Click to check!
More primary antibody please visit:
http://www.elabscience.com/index.php/product/show/tid/90
Antibody-drug conjugates employ the specific monoclonal antibodies (mAbs) to achieve targeted delivery of the conjugated cytotoxic molecules to tumor cells.
https://www.creative-biolabs.com/adc/conjugate-sites-analysis.htm
As one major component of an antibody-drug conjugate (ADC), the antibody is the key for target specificity and serves as the cargo to deliver the cytotoxic drug (payload).
https://www.creative-biolabs.com/adc/antibody-design-and-conjugation.htm
To retain antibody bioactivity, mild, near-physiological conditions are often used for conjugation reactions. Under these conditions, endogenous amino acids such as Lys and Cys are chemically reactive and can be used as conjugation sites.https://www.creative-biolabs.com/adc/antibody-design-and-conjugation.htm
As one major component of an antibody-drug conjugate (ADC), the antibody is the key for target specificity and serves as the cargo to deliver the cytotoxic drug (payload). A payload drug can be attached to different sites on an antibody using diverse conjugation chemistry. Multiple endogenous amino acids can serve as potential conjugation sites. However, to achieve more precisely controlled site-directed conjugations and subsequently a narrower distribution of drug-to-antibody ratio (DAR), special moieties with unique conjugation chemistries are engineered into antibody sequences in our antibody design services.
https://www.creative-biolabs.com/adc/antibody-design-and-conjugation.htm
CD40, also known as TNFRSF5, is a type I transmembrane protein. The molecular weight of CD40 is 48-kDa and it consists of a 193 amino acid (aa) extracellular domain, 21 aa leader sequence, 22 aa transmembrane domain, and a 62 aa intracellular domain in human (90 aa in mouse).https://www.creative-biolabs.com/adc/target-cd40-122.htm
CD30 (also known as TNFRSF8) was first identified as an antigen expressed on Hodgkin and Reed-Sternberg cells of Hodgkin's disease in 1992.https://www.creative-biolabs.com/adc/adc-development-services-targeting-cd30.htm
ADC preparation involves the chemical conjugation of the three components and depending on the conjugation strategy used, this process often yields complex and heterogeneous products.https://www.creative-biolabs.com/adc/adc-biochemical-analysis.htm
While conventional cancer therapies (surgery, chemo therapy, and radiation therapy) have shown some success in the battle again cancer, they are often accompanied by complex and sometimes, severe side-effects due to the lack of target specificity. To circumvent this flaw and improve the efficacy and safety of cancer treatment, targeted cancer therapies, especially antibody-drug conjugates (ADCs), have been actively exploited and they are gaining a significant amount of attention during the recent years.https://www.creative-biolabs.com/adc/adc-antibody-screening.htm
The elegant design of an antibody-drug conjugate is designated to achieve targeted delivery of the conjugated cytotoxic agents to tumor cells and drug release upon antigen binding and internalization, thus maximizing the antitumor effects while minimizing cytotoxicity to normal tissues. The efficacy of an ADC greatly depends on the specific antigen binding activities of the monoclonal antibody (mAb) portion of the molecule.https://www.creative-biolabs.com/adc/adc-affinity-measurement.htm
Antibody-drug conjugates (ADCs) are a unique class of novel anti-tumor agents produced by the conjugation of highly cytotoxic drug payloads with tumor specific monoclonal antibodies via elaborate chemical linkers.https://www.creative-biolabs.com/adc/adc-fc-cytotoxicity.htm
Development of 5T4-based Bispecific ADCs
A bispecific antibody can bind two different targets or two distinct epitopes on the same target. 5T4, specifically overexpressed on the cell surface of various tumors and internalized rapidly when bound to antibody, may be used as an attractive target to develop effective immunotherapy such as bispecific antibody-drug conjugate (ADC).
https://www.creative-biolabs.com/adc/development-of-5t4-based-bispecific-adcs.htm
Cancer immunotherapy is a therapy used to treat cancer patients that involves components of the immune system, commonly consisting of antibodies, vaccines, T cell infusions, and so like. https://www.creative-biolabs.com/immuno-oncology/modality.htm
✔ Registration with CTSC
✔ Preparing IND package including Cover letter, IND, 1571, 1572 form and certification form 3674.
✔ Assembling and binding volumes
✔ Submission
https://www.creative-biolabs.com/immuno-oncology/ind-publishing-and-submission.htm
For the drug development, pre-IND meeting is a critical tool to discuss the needs and challenges specific to the general product development, nonclinical testing, manufacturing information, protocol design or other regulatory questions defined in the Code of Federal Regulations (21 CFR 312.82). https://www.creative-biolabs.com/immuno-oncology/pre-ind-meeting.htm
✔ Clinical overviews (eCTD Module 2.5) including literature review and references
✔ Clinical summaries (eCTD Module 2.7) including clinical pharmacology, efficacy, and safety
✔ Clinical study report preparation and review (eCTD Module 5)
✔ Clinical justification documents for EU, US and other emerging Regulatory markets
✔ Gap analysis for dossiers in clinical module
✔ Clinical and nonclinical document support, handling queries during HA meetings and responding to them
✔ Technical review dossiers
✔ Biowaiver support and justification document services
https://www.creative-biolabs.com/immuno-oncology/medical-writing-and-translation.htm
To gain approval for clinical testing after finalizing the pre-clinical testing of innovative new therapies, it is a key milestone for pharmaceutical companies to apply for approval of Investigational New Drug (IND) with FDA or other agencies.https://www.creative-biolabs.com/immuno-oncology/regulatory-strategy-consulting.htm
Navigating the drug development process from early stage discovery to clinical stage is complex and expensive. https://www.creative-biolabs.com/immuno-oncology/ind-regulatory-services.htm
In the United States, the Current Good Manufacturing Practice (cGMP) is the Food and Drug Administration (FDA) 's formal regulations on the design, monitoring, control and maintenance of manufacturing processes and facilities.https://www.creative-biolabs.com/immuno-oncology/cgmp-manufacturing.htm
Pre-clinical toxicology is a study of the toxic effects of drugs in development based on statistical and quantitative analysis. https://www.creative-biolabs.com/immuno-oncology/antibody-and-protein-toxicology.htm
Pharmacology is a key component concerned with the study of drug action in animal models which is essential and determinant to IND approval and ultimate NDA approval for a drug candidate. https://www.creative-biolabs.com/immuno-oncology/antibody-and-protein-pharmacology.htm
Are you looking for a long-lasting solution to your missing tooth?
Dental implants are the most common type of method for replacing the missing tooth. Unlike dentures or bridges, implants are surgically placed in the jawbone. In layman’s terms, a dental implant is similar to the natural root of the tooth. It offers a stable foundation for the artificial tooth giving it the look, feel, and function similar to the natural tooth.
The skin is the largest organ and its health plays a vital role among the other sense organs. The skin concerns like acne breakout, psoriasis, or anything similar along the lines, finding a qualified and experienced dermatologist becomes paramount.
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7shruti jagirdar
Unit 4: MRA 103T Regulatory affairs
This guideline is directed principally toward new Molecular Entities that are
likely to have significant use in the elderly, either because the disease intended
to be treated is characteristically a disease of aging ( e.g., Alzheimer's disease) or
because the population to be treated is known to include substantial numbers of
geriatric patients (e.g., hypertension).
Travel vaccination in Manchester offers comprehensive immunization services for individuals planning international trips. Expert healthcare providers administer vaccines tailored to your destination, ensuring you stay protected against various diseases. Conveniently located clinics and flexible appointment options make it easy to get the necessary shots before your journey. Stay healthy and travel with confidence by getting vaccinated in Manchester. Visit us: www.nxhealthcare.co.uk
The Children are very vulnerable to get affected with respiratory disease.
In our country, the respiratory Disease conditions are consider as major cause for mortality and Morbidity in Child.
- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Computer in pharmaceutical research and development-Mpharm(Pharmaceutics)MuskanShingari
Statistics- Statistics is the science of collecting, organizing, presenting, analyzing and interpreting numerical data to assist in making more effective decisions.
A statistics is a measure which is used to estimate the population parameter
Parameters-It is used to describe the properties of an entire population.
Examples-Measures of central tendency Dispersion, Variance, Standard Deviation (SD), Absolute Error, Mean Absolute Error (MAE), Eigen Value
Summer is a time for fun in the sun, but the heat and humidity can also wreak havoc on your skin. From itchy rashes to unwanted pigmentation, several skin conditions become more prevalent during these warmer months.
Debunking Nutrition Myths: Separating Fact from Fiction"AlexandraDiaz101
In a world overflowing with diet trends and conflicting nutrition advice, it’s easy to get lost in misinformation. This article cuts through the noise to debunk common nutrition myths that may be sabotaging your health goals. From the truth about carbohydrates and fats to the real effects of sugar and artificial sweeteners, we break down what science actually says. Equip yourself with knowledge to make informed decisions about your diet, and learn how to navigate the complexities of modern nutrition with confidence. Say goodbye to food confusion and hello to a healthier you!
Giloy in Ayurveda - Classical Categorization and SynonymsPlanet Ayurveda
Giloy, also known as Guduchi or Amrita in classical Ayurvedic texts, is a revered herb renowned for its myriad health benefits. It is categorized as a Rasayana, meaning it has rejuvenating properties that enhance vitality and longevity. Giloy is celebrated for its ability to boost the immune system, detoxify the body, and promote overall wellness. Its anti-inflammatory, antipyretic, and antioxidant properties make it a staple in managing conditions like fever, diabetes, and stress. The versatility and efficacy of Giloy in supporting health naturally highlight its importance in Ayurveda. At Planet Ayurveda, we provide a comprehensive range of health services and 100% herbal supplements that harness the power of natural ingredients like Giloy. Our products are globally available and affordable, ensuring that everyone can benefit from the ancient wisdom of Ayurveda. If you or your loved ones are dealing with health issues, contact Planet Ayurveda at 01725214040 to book an online video consultation with our professional doctors. Let us help you achieve optimal health and wellness naturally.
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga
GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort.
How to Control Your Asthma Tips by gokuldas hospital.Gokuldas Hospital
Respiratory issues like asthma are the most sensitive issue that is affecting millions worldwide. It hampers the daily activities leaving the body tired and breathless.
The key to a good grip on asthma is proper knowledge and management strategies. Understanding the patient-specific symptoms and carving out an effective treatment likewise is the best way to keep asthma under control.
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
TP53 antibody for lung cancer
1. Antibodies for
Lung Cancer
Research
Antibodies: detection, imaging, diagnostic, etc.
Increase Your Efficiency and Value with
Consistent Performance
info@creative-biolabs.com
www.antibody-creativebiolabs.com
2. info@creative-biolabs.com www.antibody-creativebiolabs.com
The clinical statistics associated with lung cancer
indicate the aggressive nature of this deadly
malignance. Creative Biolabs offers high quality
ready-to-use catalogue antibodies, as well as flexible
and comprehensive customized services for the
antibody production to facilitate the basic discovery
of lung cancer. With high level professional scientists
and advanced antibody production platforms, we are
dedicated to offering various antibodies with superior
performance for a wide range of applications, and
designing a specific antibody project to tailor the best
service to best fit your requirements.
Trusted Antibody Quality
01
The right antibodies
for all your needs
Antibodies for
Lung Cancer Research
3. Lung Cancer
Lung cancer, characterized by uncontrolled cell
growth in lung tissues, has been the most common
cancer in the world for several decades. It's classified
as small-cell lung carcinoma (SCLC) and non-small-
cell lung carcinoma (NSCLC).
A Quick Glance at Key Targets in Lung Cancer
Kind reminder: If you are interested in any other targets, please visit our website or contact us.
Types, and associated mutant genes
02
Signaling pathway
Epigenetic factors
• MLL2
• EZH2
• TET2
• DNMT3A
• TP53
• LKB1
• PTEN
Tumour suppressor
Receptor tyrosine kinases
• EGFR
• FGFR1
• FGFR2
• ALK
• MET
• ROS1
• NTRK1
• RET
• HER2
• DDR2
• PDGFRA
• SOX2
• MYC
Transcription factor
Proteolysis
• KEAP1
• KRAS
• NF1
• BRAF
• PIK3CA
• MEK1
• NOTCH1
• MAPK
• PI3K/Akt/
mTOR
• JAK/STAT
• NOTCH1
• PTEN
• CDKN2A
Cell cycle
Ligand
• NRG1
info@creative-biolabs.com www.antibody-creativebiolabs.com
Antibodies for
Lung Cancer Research
4. Antibodies for mutated targets in Adenocarcinoma (ADC)
Targets Clone Applications Species reactivity Cat.No.
TP53
1285C WB, IHC, IF, IPS, FC Human, Mouse CBMAB-1838CQ
CBWJW-083 WB, IPS, PE Human, Mouse, Rat CBMAB-T0002-WJ
1F7 IP, M, WB Human CBMAB-0266-LY
STK11/
lkb1
27D10 WB, P, IP Human, Rat, Monkey CBMAB-S2833-CQ
4H12 WB, F, E, IC, IF Human, Mouse, Primate CBMAB-L2651-YJ
CBYJL-2345 F, IC, IF, P, WB Human, Mouse, Primate, Rat CBMAB-L2648-YJ
BRAF
CBYY-2108 IHC, P, WB Human, Monkey CBMAB-2457-YY
CBYY-2024 IC, IHC, P, WB Human, Dog, Monkey, Rat CBMAB-2373-YY
EP152Y WB, P, FC, IP Mouse, Rat, Human CBMAB-1219-CN
NRAS
RBT-NRAS IFS, P Human CBMAB-N0518-WJ
2G9 WB, F, E, IF Human CBMAB-N0517-WJ
CBWJN-0812 WB, F, IP Mouse, Rat, Human CBMAB-N3523-WJ
HER2
4D5-8
(TrasTuzumab
)
F, E, IH, MC Human CBMAB-E1659-FY
SPM495 P, WB Human, Mouse, Rat, Monkey CBMAB-E1645-FY
9G6 F, IF, C, P, IP, WB Human CBMAB-E1648-FY
RET
421R25 WB Human, Mouse CBMAB-R2215-CN
188CT11.2.3 WB, IH, IF Human CBMAB-R2207-CN
CBCNR-412 WB, IP, E, P, F, IF Mouse, Rat, Human CBMAB-R2229-CN
KRAS
9.13 IF, P, IP, WB Human CBMAB-K1514-LY
3B10-2F2 E, IF, WB Human CBMAB-K1500-LY
F132-62 IC, IF, C, P, IP Human, Mouse, Rat CBMAB-K1518-LY
EGFR
111.6 F, IC, IF, P, IP, WB Human, Mouse CBMAB-E0954-FY
Matuzumab F Human CBMAB-E0089-FY
GFR450 F, IP, N, MC Human CBMAB-E0086-FY
ALK
4C5B8 P, IP, WB Human CBMAB-A2349-YC
F-12 WB, IP, IF, E Mouse, Rat, Human CBMAB-A2353-YC
SP8 IH, IC, IF, P Human, Mouse CBMAB-A2354-YC
NTRK1
TrKA E, WB Human CBMAB-N3786-WJ
5B6 WB, IH Human CBMAB-N3779-WJ
CBYJT-1521 WB, IP, P, F, IC, IF Human, Rat, Mouse CBMAB-T0555-YJ
CTNNB1
8E4 E, IC/IF, WB, P Human, Mouse, Rat CBMAB-C9162-LY
7A7 IA, IF, P, WB Human, Mouse, Rat CBMAB-C8567-LY
6B3 WB, IP, P, C
Human, Mouse, Rat, Monkey,
Xenopus, Cattle, Dog, Pig
CBMAB-C8091-LY
ROS1
1F3 WB, IH Human CBMAB-R3226-CN
ROS195G WB, IH, IP, IF, E Human, Mouse CBMAB-P2695-YC
C-ROS
WB, F, IH, IP, FN, IF,
MC
Human CBMAB-R0339-CN
MET
3D4 E, IH, IP, WB Human CBMAB-C1095-LY
1G7NB IH, IF, P, F Human CBMAB-H0399-FY
4AT259 WB, IF Human, Mouse CBMAB-H3681-FY
03 info@creative-biolabs.com www.antibody-creativebiolabs.com
Antibodies for
Lung Cancer Research
5. info@creative-biolabs.com www.antibody-creativebiolabs.com
Popular Creative Biolabs’ monoclonal antibodies for various functional factors
Creative Biolabs’ antibodies help meet your needs and budget requirements of lung cancer research,
increasing efficiency and offering the best value for a wide range of applications and specific assays.
Antibodies for mutated targets in Squamous Cell Carcinoma (SCC)
Antibodies for Epigenetic factors
Targets Clone Applications Species reactivity Cat.No.
TP53
1285C WB, IHC, IF, IPS, FC Human, Mouse CBMAB-1838CQ
CBWJW-083 WB, IPS, PE Human, Mouse, Rat CBMAB-T0002-WJ
1F7 IP, M, WB Human CBMAB-0266-LY
PDGFRA
16A1 IC, F Human CBMAB-0614CQ
2D2-1A11 E, WB Human CBMAB-P1259-YC
2Q1724 E, F, C, WB Mouse CBMAB-C5342-LY
DDR2
3B11E4 E, IC, IF, IH, P, WB Human CBMAB-D0509-YC
CBYCD-209 WB Mouse, Rat, Human CBMAB-D0511-YC
13B220 E, IH, WB Human CBMAB-D0506-YC
FGFR1
6F10 N, WB Human CBMAB-F1775-CQ
VBS-7 E, F, P, IP, WB
Cattle, Chicken, Guinea pig,
Human, Mouse, Rat
CBMAB-F1934-CQ
M2F12 E, IH, IP, WB Human, Rat CBMAB-F1935-CQ
FGFR2
1G3 E, P, WB Human CBMAB-C4163-LY
CBXF-0618 WB, IH, IF Human, Mouse CBMAB-F0671-CQ
CBXF-2166 IH, N, WB Human CBMAB-F1633-CQ
PTEN
10BA32 IF, WB Human CBMAB-1515CQ
10BA33 IF, WB Human CBMAB-1516CQ
10BA34 WB Human CBMAB-1517CQ
MET
3D4 E, IH, IP, WB Human CBMAB-C1095-LY
1G7NB IH, IF, P, F Human CBMAB-H0399-FY
4AT259 WB, IF Human, Mouse CBMAB-H3681-FY
Targets Clone Applications Species reactivity Cat.No.
MLL2
2E1 E, P, WB Human CBMAB-K1432-LY
9H13L17 F, IC, IF Human CBMAB-K1433-LY
4C10 WB, F Human CBMAB-K1429-LY
EZH2
6G4F4 WB, F, E, IH, IC, MC Human CBMAB-E0234-FY
CBFYE-0131 IC, IF, IH, IP, WB Human, Mouse, Rat CBMAB-E0257-FY
CBFYE-1430 CI Human, Mouse CBMAB-E2056-FY
TET2
TET2 WB, IP, E, C, F Human CBMAB-P0214-YC
CBYJT-2579 WB, IP Human, Mouse CBMAB-T1749-YJ
CBYJT-2575 WB, CI, IP Human CBMAB-T1745-YJ
DNMT3A
64B1446 WB, IC, IF, CI, IH Human, Mouse CBMAB-D1417-YC
64B814.1 IC, IH, WB Mouse CBMAB-D1426-YC
D23G1 WB, IP
Human, Mouse, Rat,
Monkey, Cattle, Dog, Pig
CBMAB-D1422-YC
04
Antibodies for
Lung Cancer Research
To be continued.
6. Targets Clone Applications Species reactivity Cat.No.
SOX2
CBXS-4260 CI, F, IC, IF, P, IP, WB Dog, Fish, Human, Mouse CBMAB-S0460-CQ
57CT23.3.4 E, F, IF, IH, WB Human CBMAB-S0041-CQ
CBXS-1474 WB, P, W, IF, SE Mouse, Human CBMAB-S4329-CQ
MYC
CT14.G4 F, IF Human, Primate CBMAB-C0609-CQ
CBFYM-2888
WB, CI, E, F, IH, C, P,
IP
Human, Mouse, Chicken,
Yeast
CBMAB-M3082-FY
1.N.2 IF, IP, WB Chicken, Human, Mouse, Rat CBMAB-C1982-LY
Targets Clone Applications Species reactivity Cat.No.
TP53
1285C WB, IHC, IF, IPS, FC Human, Mouse CBMAB-1838CQ
CBWJW-083 WB, IPS, PE Human, Mouse, Rat CBMAB-T0002-WJ
1F7 IP, M, WB Human CBMAB-0266-LY
LKB1
27D10 WB, P, IP Human, Rat, Monkey CBMAB-S2833-CQ
4H12 WB, F, E, IC, IF Human, Mouse, Primate CBMAB-L2651-YJ
CBYJL-2345 F, IC, IF, P, WB Human, Mouse, Primate, Rat CBMAB-L2648-YJ
PTEN
10BA32 IF, WB Human CBMAB-1515CQ
10BA33 IF, WB Human CBMAB-1516CQ
10BA34 WB Human CBMAB-1517CQ
Targets Clone Applications Species reactivity Cat.No.
KEAP1
1B4 WB, P, F Mouse, Human CBMAB-K0757-LY
1F10B6 F, IC, IF, WB Human, Mouse CBMAB-K0758-LY
4G10H9 E, IF, IH, WB Human, Mouse, Rat CBMAB-K0762-LY
Targets Clone Applications Species reactivity Cat.No.
CDKN2A
1F6 P, WB Human CBMAB-C4065-LY
1E12E10 WB, P Human, Mouse, Rat CBMAB-C3919-LY
5-C3 WB, IP, C, IC/IF Mouse CBMAB-C7384-LY
Targets Clone Applications Species reactivity Cat.No.
NRG1
7D5 P, C Mouse, Rat CBMAB-0547CQ
19R23 WB, E Human CBMAB-N3576-WJ
N120A-9 N120A-9 Mammalian CBMAB-N3582-WJ
05
Antibodies for key transcription factors
Antibodies for tumor suppressor
Antibodies for proteolysis
Antibodies for key cell cycle factors
Antibodies for key ligands
info@creative-biolabs.com www.antibody-creativebiolabs.com
Antibodies for
Lung Cancer Research
7. info@creative-biolabs.com www.antibody-creativebiolabs.com
Targets Clone Applications Species reactivity Cat.No.
EGFR
111.6 F, IC, IF, P, IP, WB Human, Mouse CBMAB-E0954-FY
Matuzumab F Human CBMAB-E0089-FY
GFR450 F, IP, N, MC Human CBMAB-E0086-FY
ERBB2
4D5-8
(TrasTuzumab)
F, E, IH, MC Human CBMAB-E1659-FY
SPM495 P, WB Human, Mouse, Rat, Monkey CBMAB-E1645-FY
9G6 F, IF, C, P, IP, WB Human CBMAB-E1648-FY
MET
3D4 E, IH, IP, WB Human CBMAB-C1095-LY
1G7NB IH, IF, P, F Human CBMAB-H0399-FY
4AT259 WB, IF Human, Mouse CBMAB-H3681-FY
FGFR1
6F10 N, WB Human CBMAB-F1775-CQ
VBS-7 E, F, P, IP, WB
Cattle, Chicken, Guinea pig,
Human, Mouse, Rat
CBMAB-F1934-CQ
M2F12 E, IH, IP, WB Human, Rat CBMAB-F1935-CQ
KIT
5C8D4 WB, E, IH, P Human CBMAB-C7434-LY
3A8 E, WB Human CBMAB-K0974-LY
104D2 F Cattle, Human, Monkey CBMAB-K0116-LY
RET
421R25 WB Human, Mouse CBMAB-R2215-CN
188CT11.2.3 WB, IH, IF Human CBMAB-R2207-CN
CBCNR-412 WB, IP, E, P, F, IF Mouse, Rat, Human CBMAB-R2229-CN
ALK
4C5B8 P, IP, WB Human CBMAB-A2349-YC
F-12 WB, IP, IF, E Mouse, Rat, Human CBMAB-A2353-YC
SP8 IH, IC, IF, P Human, Mouse CBMAB-A2354-YC
FLT3
7D6 WB Human CBMAB-C8639-LY
1A11 E Human CBMAB-C3514-LY
BV10A4 F, IP Human CBMAB-F0575-CQ
JAK2
18H11L8 IC, IF, WB Human CBMAB-0071-WJ
691R5 WB Human, Mouse, Rat CBMAB-0243-WJ
1C1 E, WB Human CBMAB-0081-WJ
KRAS
9.13 IF, P, IP, WB Human CBMAB-K1514-LY
3B10-2F2 E, IF, WB Human CBMAB-K1500-LY
F132-62 IC, IF, C, P, IP Human, Mouse, Rat CBMAB-K1518-LY
NRAS
RBT-NRAS C, P Human CBMAB-N0518-WJ
2G9 WB, F, E, IF Human CBMAB-N0517-WJ
CBWJN-0812 WB, F, IP Mouse, Rat, Human CBMAB-N3523-WJ
BRAF
CBYY-2108 IH, P, WB Human, Monkey CBMAB-2457-YY
CBYY-2024 IC, IH, P, WB Human, Dog, Monkey, Rat CBMAB-2373-YY
EP152Y WB, P, F, IP Mouse, Rat, Human CBMAB-1219-CN
MAPK1
1D1 E, IP, WB Human CBMAB-0633-YC
4C11 E, IC, IF, IH, C, P, WB Human, Mouse, Monkey CBMAB-1201-YC
5AD13MA IC, IF, P, WB Human, Mouse, Rat CBMAB-E0215-FY
NF1
2D1 E, WB Human CBMAB-N2125-W
A-12 WB, IP, IF, P, E mouse, rat, Human CBMAB-N2129-WJ
CBWJN-0652 WB, E, IP, P
Human, Mouse, Rat, Guinea
Porcine
CBMAB-N0290-WJ
Antibodies for key signaling pathways related targets in lung cancer
Antibodies for MAPK pathway
06
Antibodies for
Lung Cancer Research
To be continued.
8. info@creative-biolabs.com www.antibody-creativebiolabs.com
Targets Clone Applications Species reactivity Cat.No.
AKT
9Q7 P, WB Human, Mouse, Rat CBMAB-A2060-YC
18F10.E5 E, WB, IH Human, Mouse, Rat, Chimpanzee CBMAB-A2022-YC
3B4 IF, F, IH, WB
Human, Dog, Rat, Monkey,
Mouse
CBMAB-A2043-YC
mTOR
12F10-5F11 IF, IH, IP Common fruit fly CBMAB-0019-CN
CBFYM-1208 WB, IP, P, IC Mouse, Human CBMAB-M1365-FY
CBYJL-1176 WB, IP, P, IF Human, Mouse, Rat, Monkey CBMAB-L0675-YJ
PTEN
10BA32 IF, WB Human CBMAB-1515CQ
10BA33 IF, WB Human CBMAB-1516CQ
10BA34 WB Human CBMAB-1517CQ
Targets Clone Applications Species reactivity Cat.No.
JAK1
73/JAK1 WB, IF, IP
Human, Chicken, Canine, Frog,
Mouse, Rat
CBMAB-0255-WJ
1G1 WB, P, IF, IP Human, Mouse, Rat CBMAB-0099-WJ
7H32 E, F, IH, IP, WB Human, Mouse, Rat CBMAB-0266-WJ
STAT3
CBXS-6188
CI, E, IC, IF, P, IP,
WB
Human, Mouse, Rat CBMAB-S6630-CQ
E121-21 WB, IP, P, C Human CBMAB-S6304-CQ
9D8 CI, IC, IF, P, IP, WB
Human, Mouse, Non-human
primate, Rat
CBMAB-S2902-CQ
IL6
B-F6 IP, F, WB, IH, AP, P Human CBMAB-I2004-YY
7IL6 E, IF, WB Human, Mouse, Dog CBMAB-I1697-YY
CBYY-I1515 F, IH, IP, C, MC Mouse CBMAB-I2685-YY
Targets Clone Applications Species reactivity Cat.No.
SRC
EG107 WB, P, C, IF Mouse, Rat, Human CBMAB-S6317-CQ
CBXS-3318 F, IC, IH, IP, WB
Cattle, Hamster, Human,
Monkey, Mouse, Rat
CBMAB-S6057-CQ
5A18 WB, IH, P Human, Mouse, Rat CBMAB-S2867-CQ
p53
CBWJW-083 WB, P, PE Human, Mouse, Rat CBMAB-T0002-WJ
CBLG1-2390 IF, SE, E, WB Human CBMAB-G6398-LY
25F4 IF, IH, IP, WB Common fruit fly CBMAB-0432-LY
CDC42
11A11 WB
Human, Mouse, Rat, Cattle,
Xenopus
CBMAB-C2478-LY
CBXS-2168 WB, IP, IF, E Human CBMAB-S4931-CQ
2F4 E, IF, P, WB Human CBMAB-C5093-LY
NOTCH1
D6F11 WB, IF, F Human, Mouse, Rat CBMAB-N3026-WJ
D1E11 WB, IP, P, CI Human, Mouse, Rat CBMAB-N3024-WJ
CBWJN-0692
WB, F, IH, IF, IP, P,
MC
Human, Mouse CBMAB-N0459-WJ
07
Antibodies s for PI3K/Akt/mTOR pathway
Antibodies for JAK/STAT pathway
Antibodies for other signaling factors
Antibodies for
Lung Cancer Research
9. Specific
Yes
What's my target?
Popular
Catalogue Ab Custom Ab
No
Suit my project
Available or not in Creative Biolabs?
Order the Catalogue Ab Online
Test the Ab
Mouse or rabbit?
Specific epitope
Batch to batch reproducibility
Monoclonal Ab Polyclonal Ab
Epitope syntheses or not?
Antibody Services Guidance
Creative Biolabs owns comprehensive mono-antibody products and related
services. Please contact us for more detailed information and our team will get
back to you as soon as possible. We are always here to serve you to help promote
your projects. The list above only exhibit a small part of our products. Please visit
our website for more information. https://www.antibody-creativebiolabs.com
“
”
08 info@creative-biolabs.com www.antibody-creativebiolabs.com
Antibodies for
Lung Cancer Research
10. Custom Antibody Service Process
DeliverySubmit protein
sequence
Antigen design Antigen synthesis Antibody production
and purification
Quality control
WB IHC ELISA IP/ChIP IF/FC Functional
“
”
Highlight Features:
With extensive experience and over a decade superior antibody services for
numerous worldwide customers, Creative Biolabs has blossomed into a service
leader in the field of antibody products and services. We offer a comprehensive
set of package services and also individual modules, and aim to maximize the
success of your lung cancer research discovery and development.
A wide range of
applications
Innovative technologies and ideas
Numerous worldwide customers
High-level Ph.D. scientists and experienced technicians
High efficiency and short turnaround time
Close collaboration
Extensive forefront knowledge sharing
Advanced and one-stop platforms
09
assay
Antibodies for
Lung Cancer Research
info@creative-biolabs.com www.antibody-creativebiolabs.com
11. Expedite Your
Lung Cancer Research
Tel: 1-631-381-2994
Fax: 1-631-207-8356
45-1 Ramsey Road, Shirley, NY 11967, USA
Email: info@creative-biolabs.com
www.antibody-creativebiolabs.com The trusted antibody and
custom service & solution provider.
Our promise:
Guaranteed
product quality,
expert customer
support.
10
Leverage the expertise
of our senior scientists
to obtain monoclonal
antibodies or custom
products to fit your
project.