Ctnnb1 antibody for hepatocellular carcinomaEchoHan4
CTNNB1
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. https://www.antibody-creativebiolabs.com/symbolsearch-ctnnb1.htm
BRAF
This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. https://www.antibody-creativebiolabs.com/symbolsearch-braf.htm
Antibodies for commonly mutated targets
https://www.antibody-creativebiolabs.com/symbolsearch-tp53.htm
Innovative technologies and ideas
Numerous worldwide customers
High-level Ph.D. scientists and experienced technicians
High efficiency and short turnaround time
Close collaboration
Extensive forefront knowledge sharing
Advanced and one-stop platforms
Flt3 antibody antibodies for hematologic malignanciesCreative Biolabs
Hematologic malignancies, also known as cancer of the blood or lymph system, are classified as three main types including leukemia, lymphoma and myeloma. www.antibody-creativebiolabs.com
This document discusses the results of a BLASTx search of a DNA sequence from an operon gum between 21,000-23,000 base pairs. The top hit was to the GumC protein in Xanthomonas campestris with an E-value of 1.2e-116. Other significant hits included the GumD protein in X. campestris and proteins involved in exopolysaccharide biosynthesis and transport in organisms like Rhizobium meliloti. The BLASTx results indicate homology between the query sequence and proteins involved in gum biosynthesis.
AURA Biotechnologies provides integrated biosimilar support services including cell line generation, product characterization, lot release testing, bioassays, safety studies, and clinical services. They offer a range of products and services to support biosimilar development including ELISA kits for pharmacokinetic and immunogenicity testing, recombinant proteins, antibodies, and microbiology testing services. Their goal is to simplify biosimilar research through high quality products and customized services that meet regulatory guidelines.
In mammals, there are two broad types of stem cells: embryonic stem cells, which are isolated from the inner cell mass of blastocysts, and adult stem cells, which are found in
various tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing adult tissues. Elabscience provides 700+ antibodies for stem cells research. Worth to check!
More other antibodies:
http://www.elabscience.com/index.php/product/show/tid/73
Ctnnb1 antibody for hepatocellular carcinomaEchoHan4
CTNNB1
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. https://www.antibody-creativebiolabs.com/symbolsearch-ctnnb1.htm
BRAF
This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. https://www.antibody-creativebiolabs.com/symbolsearch-braf.htm
Antibodies for commonly mutated targets
https://www.antibody-creativebiolabs.com/symbolsearch-tp53.htm
Innovative technologies and ideas
Numerous worldwide customers
High-level Ph.D. scientists and experienced technicians
High efficiency and short turnaround time
Close collaboration
Extensive forefront knowledge sharing
Advanced and one-stop platforms
Flt3 antibody antibodies for hematologic malignanciesCreative Biolabs
Hematologic malignancies, also known as cancer of the blood or lymph system, are classified as three main types including leukemia, lymphoma and myeloma. www.antibody-creativebiolabs.com
This document discusses the results of a BLASTx search of a DNA sequence from an operon gum between 21,000-23,000 base pairs. The top hit was to the GumC protein in Xanthomonas campestris with an E-value of 1.2e-116. Other significant hits included the GumD protein in X. campestris and proteins involved in exopolysaccharide biosynthesis and transport in organisms like Rhizobium meliloti. The BLASTx results indicate homology between the query sequence and proteins involved in gum biosynthesis.
AURA Biotechnologies provides integrated biosimilar support services including cell line generation, product characterization, lot release testing, bioassays, safety studies, and clinical services. They offer a range of products and services to support biosimilar development including ELISA kits for pharmacokinetic and immunogenicity testing, recombinant proteins, antibodies, and microbiology testing services. Their goal is to simplify biosimilar research through high quality products and customized services that meet regulatory guidelines.
In mammals, there are two broad types of stem cells: embryonic stem cells, which are isolated from the inner cell mass of blastocysts, and adult stem cells, which are found in
various tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing adult tissues. Elabscience provides 700+ antibodies for stem cells research. Worth to check!
More other antibodies:
http://www.elabscience.com/index.php/product/show/tid/73
This document summarizes research on mouse models of Alzheimer's disease conducted by the RIKEN Brain Science Institute Proteolytic Neuroscience Laboratory in Japan. It discusses several generations of mouse models that were developed, including those that overexpress mutant amyloid precursor protein (APP) alone or crossed with other transgenic mice, as well as knock-in models incorporating specific APP mutations. The models have provided insights into amyloid-beta deposition and inflammation with aging. Ongoing work aims to further elucidate mechanisms of pathology and evaluate modulating factors like proteases, vaccines, and genes.
Anti dengue-virus-antibody-products-and-servicesCandySwift_NY
Dengue virus (DENV) can cause dengue fever. It is a mosquito-borne, single positive-stranded RNA virus of Flaviviridae. In recent decades, the outbreak of dengue has grown dramatically in the world. Nowadays, dengue is endemic in more than 100 countries.
https://viroantibody.creative-biolabs.com/category-dengue-virus-371.htm
Characterisation of salmonella abortusequi strains harbouring defined mutatio...Bhoj Raj Singh
This document describes research characterizing Salmonella Abortusequi strains with defined mutations in aroA, htrA and phoP/Q genes. Key findings include:
1) Mutations in aroA, htrA and phoP/Q genes were introduced into S. Abortusequi strains using genetic engineering techniques.
2) In mice, the mutant strains showed attenuated virulence and were cleared faster than the wild type strain. They also elicited stronger immune responses.
3) In macrophage cells, the mutant strains induced less cell death than the wild type and had reduced intracellular survival, suggesting impaired virulence.
The defined mutant strains showed promise as live attenuated vaccine candidates against S.
Cancer Research Antibodies - ElabscienceElabscience
Cancer is a group of diseases involving abnormal cell growth with thepotential to invade or spread to other parts of the body. Not all tumorsare cancerous; benign tumors do not spread to other parts of the body.Possible signs and symptoms include a lump, abnormal bleeding,prolonged cough, unexplained weight loss and a change in bowelmovements. While these symptoms may indicate cancer, they mayhave other causes.Over 100 cancers affect humans. Elabsciece has 690+ antibodies for cancer research. Click to check!
More primary antibody please visit:
http://www.elabscience.com/index.php/product/show/tid/90
A recombinant chimeric protein was constructed containing a tandem dimer of the antigenic site A from the VP1 capsid protein of foot-and-mouth disease virus inserted within the vesicular stomatitis virus G protein. This chimeric protein was able to correctly display the foot-and-mouth disease virus epitope and elicit a neutralizing immune response in vaccinated cattle when administered as both a DNA and baculovirus-expressed vaccine.
Hemangioma is a congenital benign tumor or vascular malformation. It is common in babies at birth or shortly after birth. The cause of hemangioma is currently unknown; however, several studies have suggested the importance of estrogen signaling in hemangioma proliferation.More info visit: http://www.elabscience.com
1) The document discusses homology modeling of the vp40 matrix protein of Ebola virus through various bioinformatics tools since its 3D structure is unknown.
2) Physicochemical characterization of the protein was done and its secondary structure was predicted.
3) Homology modeling was performed using Geno3D and SwissModel and the model was assessed using tools like PROCHECK, PSIPRED, and PHYRE.
4) The SwissModel generated structure was found to be more accurate and this predicted 3D structure can be used for structure-based drug design and vaccine development against Ebola virus.
This document discusses non-invasive imaging of vulnerable plaque using macrophage imaging with targeted contrast agents such as superparamagnetic iron oxide (SPIO) nanoparticles. SPIO nanoparticles are engulfed by macrophages and accumulate in inflamed plaques, shortening MRI relaxation times and allowing identification of active versus inactive plaques. Studies in animal models demonstrate the feasibility of SPIO-enhanced MRI for detecting vulnerable plaques. However, limitations include the need for further improvements in spatial and temporal resolution for coronary applications as well as the added cost and complexity compared to alternative diagnostic methods.
PAR3 is expressed on mouse lymphocytes and myeloid cells, particularly B lymphocytes. The PAR3 receptor on B lymphocytes is functionally active and involved in regulating lymphocyte proliferation and activation in response to thrombin. PAR3 may represent an important link between the coagulation and immune systems. A monoclonal antibody (mAb 8E8) was characterized that specifically binds to the cleavage site of mouse PAR3. This antibody blocked thrombin-induced platelet aggregation and calcium signaling in platelets and splenocytes. It also inhibited proliferation of a hybridoma cell line in response to thrombin or PAR3 peptides but not PAR4 peptides. The antibody further suppressed activation of splenocytes induced by anti-CD3/anti-CD40 stimulation
Hepatocellular carcinoma (HCC), with a prevalence of around 600,000 people worldwide, is the sixth most common cancer globally. www.antibody-creativebiolabs.com
Melanoma, the deadliest skin cancers, is caused by
the transformation of melanocytes which accumulate genetic alterations, leading to abnormal proliferation and dissemination. www.antibody-creativebiolabs.com
Antibody arrays are valuable for the parallel analysis of multiple proteins in small sample volumes. The earliest and most widely used application of antibody arrays has been to measure multiple protein abundances, using sandwich assays and label-based assays, for biomarker discovery and biological studies. Modifications to these assays have led to studies profiling specific protein post-translational modifications, such as protein phosphorylation that is a mechanism of regulation that is extremely important in most cellular processes.
https://www.antibody-creativebiolabs.com/category-introduction/antibody-array-analysis-132.htm
Lung cancer, characterized by uncontrolled cell
growth in lung tissues, has been the most common
cancer in the world for several decades. It's classified
as small-cell lung carcinoma (SCLC) and non-smallcell
lung carcinoma (NSCLC). www.antibody-creativebiolabs.com
Lung cancer, characterized by uncontrolled cell growth in lung tissues, has been the most common cancer in the world for several decades. It's classified as small-cell lung carcinoma (SCLC) and non-smallcell lung carcinoma (NSCLC).https://www.antibody-creativebiolabs.com/anti-tp53-antibody-cf448-633983.htm
Secondary antibodies bind to the primary antibody to assist in detection, classification and isolation of interest antigen. To ensure detection, the secondary antibody must be specific for the isotype and antibody species of the primary antibody in the application. Secondary antibodies are typically polyclonal.
Secondary antibody conjugates are important tools in biochemical and cell-based analysis. Enzyme-labeled secondary antibodies have high catalytic turnover rates and are routinely used in various assays for their robust and rapid signal generation. Secondary antibodies conjugated to fluorescent dyes offer brighter signals and multiplexing capabilities in cell analysis and protein analysis applications including immunofluorescence microscopy and cell imaging. For both enzyme-labeled and dye-labeled secondary antibodies, high sensitivity and signal amplification are two desirable qualities when detecting target antigens of low abundance.
The human brain remains a great mystery in science and current research strives to understand molecular and cellular processes of the nervous system.https://www.antibody-creativebiolabs.com/search.aspx?key=neuroscience&ty=tag
Antibody arrays have emerged as an important tool, which enable multiplexed protein expression profiling such as cytokines, chemokines and growth factors, which may be involved in diseases. To design high-performing antibody arrays, it is necessary to develop an integrated technology platform, where the interplay between the surfaces and the antibody is anticipated to play an important role.
https://www.antibody-creativebiolabs.com/category/glass-slide-antibody-arrays-126.htm
Anti gfap antibodies for neuroscience research creative biolabsCreative Biolabs
The human brain remains a great mystery in science and current research
strives to understand molecular and cellular processes of the nervous
system. The prevention and effective treatment of neurological disorders
like Alzheimer's and Parkinson's diseases has been a major medical
challenge. Creative Biolabs offers a broad range of antibodies to help you
win the race in your discovery of the nervous system. www.antibody-creativebiolabs.com
This document provides information on antibodies for breast cancer research from Creative Biolabs. It discusses the types and prevalence of breast cancer and key markers. It then provides a table listing antibodies for commonly mutated targets in breast cancer research, including targets, clone, applications and species reactivity. The document also discusses popular antibodies for other key markers and signaling factors involved in breast cancer.
Breast cancer is the principle cause of cancer-related mortality
among women worldwide. It's highly heterogeneous and can be
classified into 3 types - TNBC, HER2+ and Luminal (non-HER2+). www.antibody-creativebiolabs.com
The document discusses immunotherapy and immunological checkpoint treatment. It provides background on how immunotherapy works to activate the immune system against tumors. Immunological checkpoint treatment in particular has shown promise, with FDA approval of antibodies against CTLA-4 and PD-1. Ongoing research is exploring additional immunosuppressive targets like LAG-3, TIM-3, and TIGIT. The document also lists antibodies available from Creative Biolabs that target checkpoints like CTLA-4, PD-1, and IL-17A for research purposes.
Creative Biolabs offers a comprehensive range of quality recombinant antibodies for cell & organelle imaging. These antibodies are covering significant research areas such as cancer research, cell signaling, cell morphology and organelle detection.
Live cell imaging is the study of living cells using time-lapse microscopy. Scientists use it to better understand and validate the biological function through the study of cellular dynamics. Organelles are specialized and well-defined parts of the cell which are usually separately enclosed within their own lipid bilayers. Very often organelles have to be stained to follow cellular processes and the effects of changing parameters on these processes. Thus, there is a great significance and strong need for tools to stain and follow specific organelles in living cells.
https://www.antibody-creativebiolabs.com/category-introduction/cell-organelle-imaging-3.htm
This document summarizes research on mouse models of Alzheimer's disease conducted by the RIKEN Brain Science Institute Proteolytic Neuroscience Laboratory in Japan. It discusses several generations of mouse models that were developed, including those that overexpress mutant amyloid precursor protein (APP) alone or crossed with other transgenic mice, as well as knock-in models incorporating specific APP mutations. The models have provided insights into amyloid-beta deposition and inflammation with aging. Ongoing work aims to further elucidate mechanisms of pathology and evaluate modulating factors like proteases, vaccines, and genes.
Anti dengue-virus-antibody-products-and-servicesCandySwift_NY
Dengue virus (DENV) can cause dengue fever. It is a mosquito-borne, single positive-stranded RNA virus of Flaviviridae. In recent decades, the outbreak of dengue has grown dramatically in the world. Nowadays, dengue is endemic in more than 100 countries.
https://viroantibody.creative-biolabs.com/category-dengue-virus-371.htm
Characterisation of salmonella abortusequi strains harbouring defined mutatio...Bhoj Raj Singh
This document describes research characterizing Salmonella Abortusequi strains with defined mutations in aroA, htrA and phoP/Q genes. Key findings include:
1) Mutations in aroA, htrA and phoP/Q genes were introduced into S. Abortusequi strains using genetic engineering techniques.
2) In mice, the mutant strains showed attenuated virulence and were cleared faster than the wild type strain. They also elicited stronger immune responses.
3) In macrophage cells, the mutant strains induced less cell death than the wild type and had reduced intracellular survival, suggesting impaired virulence.
The defined mutant strains showed promise as live attenuated vaccine candidates against S.
Cancer Research Antibodies - ElabscienceElabscience
Cancer is a group of diseases involving abnormal cell growth with thepotential to invade or spread to other parts of the body. Not all tumorsare cancerous; benign tumors do not spread to other parts of the body.Possible signs and symptoms include a lump, abnormal bleeding,prolonged cough, unexplained weight loss and a change in bowelmovements. While these symptoms may indicate cancer, they mayhave other causes.Over 100 cancers affect humans. Elabsciece has 690+ antibodies for cancer research. Click to check!
More primary antibody please visit:
http://www.elabscience.com/index.php/product/show/tid/90
A recombinant chimeric protein was constructed containing a tandem dimer of the antigenic site A from the VP1 capsid protein of foot-and-mouth disease virus inserted within the vesicular stomatitis virus G protein. This chimeric protein was able to correctly display the foot-and-mouth disease virus epitope and elicit a neutralizing immune response in vaccinated cattle when administered as both a DNA and baculovirus-expressed vaccine.
Hemangioma is a congenital benign tumor or vascular malformation. It is common in babies at birth or shortly after birth. The cause of hemangioma is currently unknown; however, several studies have suggested the importance of estrogen signaling in hemangioma proliferation.More info visit: http://www.elabscience.com
1) The document discusses homology modeling of the vp40 matrix protein of Ebola virus through various bioinformatics tools since its 3D structure is unknown.
2) Physicochemical characterization of the protein was done and its secondary structure was predicted.
3) Homology modeling was performed using Geno3D and SwissModel and the model was assessed using tools like PROCHECK, PSIPRED, and PHYRE.
4) The SwissModel generated structure was found to be more accurate and this predicted 3D structure can be used for structure-based drug design and vaccine development against Ebola virus.
This document discusses non-invasive imaging of vulnerable plaque using macrophage imaging with targeted contrast agents such as superparamagnetic iron oxide (SPIO) nanoparticles. SPIO nanoparticles are engulfed by macrophages and accumulate in inflamed plaques, shortening MRI relaxation times and allowing identification of active versus inactive plaques. Studies in animal models demonstrate the feasibility of SPIO-enhanced MRI for detecting vulnerable plaques. However, limitations include the need for further improvements in spatial and temporal resolution for coronary applications as well as the added cost and complexity compared to alternative diagnostic methods.
PAR3 is expressed on mouse lymphocytes and myeloid cells, particularly B lymphocytes. The PAR3 receptor on B lymphocytes is functionally active and involved in regulating lymphocyte proliferation and activation in response to thrombin. PAR3 may represent an important link between the coagulation and immune systems. A monoclonal antibody (mAb 8E8) was characterized that specifically binds to the cleavage site of mouse PAR3. This antibody blocked thrombin-induced platelet aggregation and calcium signaling in platelets and splenocytes. It also inhibited proliferation of a hybridoma cell line in response to thrombin or PAR3 peptides but not PAR4 peptides. The antibody further suppressed activation of splenocytes induced by anti-CD3/anti-CD40 stimulation
Hepatocellular carcinoma (HCC), with a prevalence of around 600,000 people worldwide, is the sixth most common cancer globally. www.antibody-creativebiolabs.com
Melanoma, the deadliest skin cancers, is caused by
the transformation of melanocytes which accumulate genetic alterations, leading to abnormal proliferation and dissemination. www.antibody-creativebiolabs.com
Antibody arrays are valuable for the parallel analysis of multiple proteins in small sample volumes. The earliest and most widely used application of antibody arrays has been to measure multiple protein abundances, using sandwich assays and label-based assays, for biomarker discovery and biological studies. Modifications to these assays have led to studies profiling specific protein post-translational modifications, such as protein phosphorylation that is a mechanism of regulation that is extremely important in most cellular processes.
https://www.antibody-creativebiolabs.com/category-introduction/antibody-array-analysis-132.htm
Lung cancer, characterized by uncontrolled cell
growth in lung tissues, has been the most common
cancer in the world for several decades. It's classified
as small-cell lung carcinoma (SCLC) and non-smallcell
lung carcinoma (NSCLC). www.antibody-creativebiolabs.com
Lung cancer, characterized by uncontrolled cell growth in lung tissues, has been the most common cancer in the world for several decades. It's classified as small-cell lung carcinoma (SCLC) and non-smallcell lung carcinoma (NSCLC).https://www.antibody-creativebiolabs.com/anti-tp53-antibody-cf448-633983.htm
Secondary antibodies bind to the primary antibody to assist in detection, classification and isolation of interest antigen. To ensure detection, the secondary antibody must be specific for the isotype and antibody species of the primary antibody in the application. Secondary antibodies are typically polyclonal.
Secondary antibody conjugates are important tools in biochemical and cell-based analysis. Enzyme-labeled secondary antibodies have high catalytic turnover rates and are routinely used in various assays for their robust and rapid signal generation. Secondary antibodies conjugated to fluorescent dyes offer brighter signals and multiplexing capabilities in cell analysis and protein analysis applications including immunofluorescence microscopy and cell imaging. For both enzyme-labeled and dye-labeled secondary antibodies, high sensitivity and signal amplification are two desirable qualities when detecting target antigens of low abundance.
The human brain remains a great mystery in science and current research strives to understand molecular and cellular processes of the nervous system.https://www.antibody-creativebiolabs.com/search.aspx?key=neuroscience&ty=tag
Antibody arrays have emerged as an important tool, which enable multiplexed protein expression profiling such as cytokines, chemokines and growth factors, which may be involved in diseases. To design high-performing antibody arrays, it is necessary to develop an integrated technology platform, where the interplay between the surfaces and the antibody is anticipated to play an important role.
https://www.antibody-creativebiolabs.com/category/glass-slide-antibody-arrays-126.htm
Anti gfap antibodies for neuroscience research creative biolabsCreative Biolabs
The human brain remains a great mystery in science and current research
strives to understand molecular and cellular processes of the nervous
system. The prevention and effective treatment of neurological disorders
like Alzheimer's and Parkinson's diseases has been a major medical
challenge. Creative Biolabs offers a broad range of antibodies to help you
win the race in your discovery of the nervous system. www.antibody-creativebiolabs.com
This document provides information on antibodies for breast cancer research from Creative Biolabs. It discusses the types and prevalence of breast cancer and key markers. It then provides a table listing antibodies for commonly mutated targets in breast cancer research, including targets, clone, applications and species reactivity. The document also discusses popular antibodies for other key markers and signaling factors involved in breast cancer.
Breast cancer is the principle cause of cancer-related mortality
among women worldwide. It's highly heterogeneous and can be
classified into 3 types - TNBC, HER2+ and Luminal (non-HER2+). www.antibody-creativebiolabs.com
The document discusses immunotherapy and immunological checkpoint treatment. It provides background on how immunotherapy works to activate the immune system against tumors. Immunological checkpoint treatment in particular has shown promise, with FDA approval of antibodies against CTLA-4 and PD-1. Ongoing research is exploring additional immunosuppressive targets like LAG-3, TIM-3, and TIGIT. The document also lists antibodies available from Creative Biolabs that target checkpoints like CTLA-4, PD-1, and IL-17A for research purposes.
Creative Biolabs offers a comprehensive range of quality recombinant antibodies for cell & organelle imaging. These antibodies are covering significant research areas such as cancer research, cell signaling, cell morphology and organelle detection.
Live cell imaging is the study of living cells using time-lapse microscopy. Scientists use it to better understand and validate the biological function through the study of cellular dynamics. Organelles are specialized and well-defined parts of the cell which are usually separately enclosed within their own lipid bilayers. Very often organelles have to be stained to follow cellular processes and the effects of changing parameters on these processes. Thus, there is a great significance and strong need for tools to stain and follow specific organelles in living cells.
https://www.antibody-creativebiolabs.com/category-introduction/cell-organelle-imaging-3.htm
April 2014 - Antibodies Newsflash - BBI SolutionsBBISolutions
This month’s newsflash focuses on our recombinant Fab antibodies. Find out more about their clinical relevance and see new performance data for Cystatin C, Myeloperoxidase and C Reactive Protein recombinant Fab antibodies.
Kinases belong to the family of phosphotransferases and play critical roles in the process known as phosphorylation in which a phosphorylated substrate and ADP are produced.
https://www.creative-biogene.com/products/kinase-stable-cell-lines.html
The document discusses the development and benefits of cryopreserved human peripheral blood mononuclear cell (PBMC) libraries with defined HLA types and antigen reactivities. Key points include:
1) Protocols were established for functionally loss-free freezing and thawing of PBMCs.
2) A reference PBMC library was created with over 70 donors characterized for HLA type and immune responses.
3) Serum-free media was developed and implemented for PBMC processing and testing.
4) The libraries provide standardized access to characterized PBMCs for immunological research and assays.
Neuroscience is the scientific study of the nervous system. The scope of neuroscience has broadened to include different approaches used to study the molecular, cellular, developmental, structural, functional, evolutionary, computational, and medical aspects of the nervous system. Elabscience offers 380+ antibodies for your neuroscience research.
Click for more antibodies:
http://www.elabscience.com/index.php/product/show/tid/90
The document discusses StatLab's new line of immunohistochemistry (IHC) reagents, including ready-to-use antibodies for various markers in pre-diluted formats of 6mL or 10mL. It provides a table listing over 100 monoclonal and polyclonal antibody options across various species and clones. The document promotes StatLab IHC reagents as delivering high quality staining at an economical cost for pathologists and histotechnologists.
Neutralizing antibodies for infectious diseases.pdfthomasm2014
Creative Diagnostics offers a wide selection of neutralizing antibodies that can be used for applications like ELISA assays, neutralization experiments, and more. They provide monoclonal antibodies for pathogens like adenovirus, alphaviruses, astrovirus, and others. Their proprietary cloning platform allows them to produce recombinant versions of these antibodies, which are valuable for vaccine development and diagnostic research.
Similar to Cd96 antibody for t cell co signaling research (20)
Recently, the development of molecular biotechnology allows modifications of viral genomes genetically and optimizes the transformation of available viruses with weak pathogenicity. These methods are used to enhance the oncolytic effect and reduce adverse reactions to maximize both efficacy and safety. Indeed, the oncolytic virus can stimulate a pro-inflammatory tumor environment by enhancing antigen recognition and robust immune responses. It overcomes the immune evasiveness and escape of malignant cells to eliminate the tumor cells.
https://www.creative-biolabs.com/oncolytic-virus/definition-of-an-oncolytic-virus.htm
An oncolytic virus is a form of promising therapeutic tool for the treatment of malignant tumors, which uses viruses to selectively infect and kill tumor cells and further to induce or boost specific antitumor immunity. https://www.creative-biolabs.com/oncolytic-virus/definition-of-an-oncolytic-virus.htm
Oncolytic viruses encoding reporter genes utilized for in vivo molecular imaging are useful to locate the distribution of oncolytic viruses in pre-clinical tests. Optical detection methods mainly include green fluorescent protein (GFP), enhanced GFP (eGFP), discosoma red fluorescent protein (DsRed), and bioluminescence imaging (BLI), which utilizes luciferases. Reporter-encoding oncolytic viruses, including vaccinia virus, adenovirus, herpes simplex virus and vesicular stomatitis virus, allow accurate tracking of gene expression, tumor metastases, viral infection as well as assessment of gene therapy.
https://www.creative-biolabs.com/oncolytic-virus/category-reporter-encoding-oncolytic-virus-293.htm
Vaccinia virus can accommodate more than 30 kb of foreign DNA. Foreign genes can be stably integrated into the viral genome, resulting in efficient and long-term gene expression. The deletion of the viral genes of thymidine kinase (TK) and vaccinia growth factors (VGF) results in enhanced tumor-selectively and antitumor activity, and reduced virus virulence. https://www.creative-biolabs.com/oncolytic-virus/category-pre-made-oncolytic-vaccinia-virus-291.htm
Oncolytic viruses are a class of antitumor agents that selectively kill tumor cells without affecting normal cells. Vaccinia virus (VACV) is a large, enveloped virus that is considered as the most potential live biotherapeutic agent because of its strong oncolytic efficacy and potent antigen presentation capability that can combine well with its natural oncolytic activities for cancer immunotherapy. Many types of modified vaccinia virus have been used for in vitro and in vivo studies, as well as clinical trials.https://www.creative-biolabs.com/oncolytic-virus/category-pre-made-oncolytic-vaccinia-virus-291.htm
Partial deletion of the HSV gene results in superior packaging capacity of >30 kb foreign DNA with low toxicity as an expression vector. Multiple modified purified oncolytic herpes simplex virus (oHSV) products can avoid evading the host immune response and reduce toxicity by gene knock-out, such as ICP0, ICP4, ICP22, ICP27 or ICP47.https://www.creative-biolabs.com/oncolytic-virus/category-pre-made-oncolytic-herpes-simplex-virus-290.htm
Oncolytic viruses are using for the treatment of cancer due to the specific antitumor activity in tumor cells. Herpes simplex virus (HSV) is a human neurogenic dsDNA virus that has the characteristic of life-long latent infection of neurons and allows for long-term transgene expression.https://www.creative-biolabs.com/oncolytic-virus/category-pre-made-oncolytic-herpes-simplex-virus-290.htm
Oncolytic viruses have the potential to powerfully and selectively kill cancer cells and have shown impressive efficacy in preclinical and clinical settings. However, their potential can be restricted by inefficient delivery into the complex tumor environment. Thus, the efficient delivery of oncolytic viruses remains a significant challenge in the field of oncology, limiting their therapeutic effect. https://www.creative-biolabs.com/oncolytic-virus/approaches-to-delivery-of-oncolytic-viruses.htm
Numerous viruses are being developed pre-clinically and clinically. An investigation of all registered clinical trials in 2017 demonstrates 78 interventional trials regarding OVs. This ability for near-universal therapeutic impact in cancer makes OVs a popular therapeutic tool. Today, both preclinical and early-stage clinical trials are intensively investigating the approach to improve oncolytic virotherapy.
https://www.creative-biolabs.com/oncolytic-virus/applications-of-oncolytic-viruses-in-cancer-treatment.htm
To fully optimize oncolytic virotherapy and provide meaningful mechanistic insight, it is important to have representative animal models of oncolysis in various tumor types. https://www.creative-biolabs.com/oncolytic-virus/animal-models-for-oncolytic-virus-study.htm
Abciximab (also known as abcixifiban or c7E3 Fab), is the Fab fragment of the chimeric human-murine, monoclonal antibody 7E3. It is composed of murine variable regions and human constant regions.https://www.creativebiolabs.net/abciximab-overview.htm
Abagovomab is a murine monoclonal anti-idiotypic antibody (MW: 165-175 kDa), produced by a mouse hybridoma and generated against OC125, which serves to functionally imitate the human cancer antigen 125 (CA-125). https://www.creativebiolabs.net/abagovomab-overview.htm
Wnt comprises a diverse family of secreted lipid-modified signaling glycoproteins that are 350-400 amino acids in length. Wnt is an acronym in the field of genetics that stands for 'Wingless/Integrated'.https://www.creativebiolabs.net/wnt-signaling-pathway.htm
TNF works through two receptors, TNFR1 and TNFR2. TNFR1 is the major signal receptor of TNF-α. TNFR2, which mediates limited biological responses, binds to TNF-α and TNF-β. TNF signaling transduction through TNFR1 and TNFR2 can induce a variety of cellular responses, which depends on many factors, including the metabolic state of the cell and the adaptor proteins present in the cell.https://www.creativebiolabs.net/tnf-signaling-pathway.htm
Innate immune receptors, also known as pattern recognition receptors (PRRs), have been identified in the serum, on the cell surface, in endosomes, and in the cytoplasm. Toll-like receptors (TLRs) is one of the particularly important groups of PRRs.https://www.creativebiolabs.net/tlr-signal-pathway.htm
Transforming growth factor beta (TGF-β) is a cytokine that participates in both physiological and pathological processes.https://www.creativebiolabs.net/tgf-beta-signaling-pathway.htm
T-cell receptor (TCR) is a heterodimers composed of α and β peptide chains. TCR is mainly responsible for recognizing the antigens presented by major histocompatibility complex (MHC) molecules on the surface of antigen presenting cells (APC).https://www.creativebiolabs.net/tcr-signal-pathway.htm
Ras, which is a low-molecular-weight GDP/GTP-binding guanine triphosphatase, is the prototypical member of the Ras superfamily of proteins. https://www.creativebiolabs.net/ras-signaling-pathway.htm
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors, which are responsible for regulating gene expression.https://www.creativebiolabs.net/ppar-signaling-pathway.htm
PI3K-Akt signaling pathway is one of the important signal transduction pathways in cells. It is involved in regulating cell metabolism, growth, proliferation, survival, transcription and protein synthesis by affecting the activation of downstream effector molecules. https://www.creativebiolabs.net/pi3k-akt-signaling-pathway.htm
BREEDING METHODS FOR DISEASE RESISTANCE.pptxRASHMI M G
Plant breeding for disease resistance is a strategy to reduce crop losses caused by disease. Plants have an innate immune system that allows them to recognize pathogens and provide resistance. However, breeding for long-lasting resistance often involves combining multiple resistance genes
Phenomics assisted breeding in crop improvementIshaGoswami9
As the population is increasing and will reach about 9 billion upto 2050. Also due to climate change, it is difficult to meet the food requirement of such a large population. Facing the challenges presented by resource shortages, climate
change, and increasing global population, crop yield and quality need to be improved in a sustainable way over the coming decades. Genetic improvement by breeding is the best way to increase crop productivity. With the rapid progression of functional
genomics, an increasing number of crop genomes have been sequenced and dozens of genes influencing key agronomic traits have been identified. However, current genome sequence information has not been adequately exploited for understanding
the complex characteristics of multiple gene, owing to a lack of crop phenotypic data. Efficient, automatic, and accurate technologies and platforms that can capture phenotypic data that can
be linked to genomics information for crop improvement at all growth stages have become as important as genotyping. Thus,
high-throughput phenotyping has become the major bottleneck restricting crop breeding. Plant phenomics has been defined as the high-throughput, accurate acquisition and analysis of multi-dimensional phenotypes
during crop growing stages at the organism level, including the cell, tissue, organ, individual plant, plot, and field levels. With the rapid development of novel sensors, imaging technology,
and analysis methods, numerous infrastructure platforms have been developed for phenotyping.
DERIVATION OF MODIFIED BERNOULLI EQUATION WITH VISCOUS EFFECTS AND TERMINAL V...Wasswaderrick3
In this book, we use conservation of energy techniques on a fluid element to derive the Modified Bernoulli equation of flow with viscous or friction effects. We derive the general equation of flow/ velocity and then from this we derive the Pouiselle flow equation, the transition flow equation and the turbulent flow equation. In the situations where there are no viscous effects , the equation reduces to the Bernoulli equation. From experimental results, we are able to include other terms in the Bernoulli equation. We also look at cases where pressure gradients exist. We use the Modified Bernoulli equation to derive equations of flow rate for pipes of different cross sectional areas connected together. We also extend our techniques of energy conservation to a sphere falling in a viscous medium under the effect of gravity. We demonstrate Stokes equation of terminal velocity and turbulent flow equation. We look at a way of calculating the time taken for a body to fall in a viscous medium. We also look at the general equation of terminal velocity.
Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...Travis Hills MN
Travis Hills of Minnesota developed a method to convert waste into high-value dry fertilizer, significantly enriching soil quality. By providing farmers with a valuable resource derived from waste, Travis Hills helps enhance farm profitability while promoting environmental stewardship. Travis Hills' sustainable practices lead to cost savings and increased revenue for farmers by improving resource efficiency and reducing waste.
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...University of Maribor
Slides from talk:
Aleš Zamuda: Remote Sensing and Computational, Evolutionary, Supercomputing, and Intelligent Systems.
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Inter-Society Networking Panel GRSS/MTT-S/CIS Panel Session: Promoting Connection and Cooperation
https://www.etran.rs/2024/en/home-english/
hematic appreciation test is a psychological assessment tool used to measure an individual's appreciation and understanding of specific themes or topics. This test helps to evaluate an individual's ability to connect different ideas and concepts within a given theme, as well as their overall comprehension and interpretation skills. The results of the test can provide valuable insights into an individual's cognitive abilities, creativity, and critical thinking skills
ANAMOLOUS SECONDARY GROWTH IN DICOT ROOTS.pptxRASHMI M G
Abnormal or anomalous secondary growth in plants. It defines secondary growth as an increase in plant girth due to vascular cambium or cork cambium. Anomalous secondary growth does not follow the normal pattern of a single vascular cambium producing xylem internally and phloem externally.
The debris of the ‘last major merger’ is dynamically youngSérgio Sacani
The Milky Way’s (MW) inner stellar halo contains an [Fe/H]-rich component with highly eccentric orbits, often referred to as the
‘last major merger.’ Hypotheses for the origin of this component include Gaia-Sausage/Enceladus (GSE), where the progenitor
collided with the MW proto-disc 8–11 Gyr ago, and the Virgo Radial Merger (VRM), where the progenitor collided with the
MW disc within the last 3 Gyr. These two scenarios make different predictions about observable structure in local phase space,
because the morphology of debris depends on how long it has had to phase mix. The recently identified phase-space folds in Gaia
DR3 have positive caustic velocities, making them fundamentally different than the phase-mixed chevrons found in simulations
at late times. Roughly 20 per cent of the stars in the prograde local stellar halo are associated with the observed caustics. Based
on a simple phase-mixing model, the observed number of caustics are consistent with a merger that occurred 1–2 Gyr ago.
We also compare the observed phase-space distribution to FIRE-2 Latte simulations of GSE-like mergers, using a quantitative
measurement of phase mixing (2D causticality). The observed local phase-space distribution best matches the simulated data
1–2 Gyr after collision, and certainly not later than 3 Gyr. This is further evidence that the progenitor of the ‘last major merger’
did not collide with the MW proto-disc at early times, as is thought for the GSE, but instead collided with the MW disc within
the last few Gyr, consistent with the body of work surrounding the VRM.
Nucleophilic Addition of carbonyl compounds.pptxSSR02
Nucleophilic addition is the most important reaction of carbonyls. Not just aldehydes and ketones, but also carboxylic acid derivatives in general.
Carbonyls undergo addition reactions with a large range of nucleophiles.
Comparing the relative basicity of the nucleophile and the product is extremely helpful in determining how reversible the addition reaction is. Reactions with Grignards and hydrides are irreversible. Reactions with weak bases like halides and carboxylates generally don’t happen.
Electronic effects (inductive effects, electron donation) have a large impact on reactivity.
Large groups adjacent to the carbonyl will slow the rate of reaction.
Neutral nucleophiles can also add to carbonyls, although their additions are generally slower and more reversible. Acid catalysis is sometimes employed to increase the rate of addition.
The ability to recreate computational results with minimal effort and actionable metrics provides a solid foundation for scientific research and software development. When people can replicate an analysis at the touch of a button using open-source software, open data, and methods to assess and compare proposals, it significantly eases verification of results, engagement with a diverse range of contributors, and progress. However, we have yet to fully achieve this; there are still many sociotechnical frictions.
Inspired by David Donoho's vision, this talk aims to revisit the three crucial pillars of frictionless reproducibility (data sharing, code sharing, and competitive challenges) with the perspective of deep software variability.
Our observation is that multiple layers — hardware, operating systems, third-party libraries, software versions, input data, compile-time options, and parameters — are subject to variability that exacerbates frictions but is also essential for achieving robust, generalizable results and fostering innovation. I will first review the literature, providing evidence of how the complex variability interactions across these layers affect qualitative and quantitative software properties, thereby complicating the reproduction and replication of scientific studies in various fields.
I will then present some software engineering and AI techniques that can support the strategic exploration of variability spaces. These include the use of abstractions and models (e.g., feature models), sampling strategies (e.g., uniform, random), cost-effective measurements (e.g., incremental build of software configurations), and dimensionality reduction methods (e.g., transfer learning, feature selection, software debloating).
I will finally argue that deep variability is both the problem and solution of frictionless reproducibility, calling the software science community to develop new methods and tools to manage variability and foster reproducibility in software systems.
Exposé invité Journées Nationales du GDR GPL 2024
The binding of cosmological structures by massless topological defectsSérgio Sacani
Assuming spherical symmetry and weak field, it is shown that if one solves the Poisson equation or the Einstein field
equations sourced by a topological defect, i.e. a singularity of a very specific form, the result is a localized gravitational
field capable of driving flat rotation (i.e. Keplerian circular orbits at a constant speed for all radii) of test masses on a thin
spherical shell without any underlying mass. Moreover, a large-scale structure which exploits this solution by assembling
concentrically a number of such topological defects can establish a flat stellar or galactic rotation curve, and can also deflect
light in the same manner as an equipotential (isothermal) sphere. Thus, the need for dark matter or modified gravity theory is
mitigated, at least in part.
1. Antibodies for
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Antibodies: detection, imaging, diagnostic, etc.
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3. Ig Superfamily TNF Superfamily
B7/CD28 families; Butyrophilis;
Nectin and nectin-like binding receptors;
SLAM family; TIM family receptors & ligands.
Type V Subfamily Receptors & Ligands;
Type L Subfamily Receptors & Ligands.
T Cell Co-Signaling
T cell activation requires two signals. One is recognition of the antigenic peptide/major
histocompatibility complex (MHC) by the T cell receptor (TCR); another is antigen
independent co-stimulation induced by interactions between co-signaling molecules
expressed on antigen-presenting cells (APCs) and their T cell-expressed receptors.
Co-stimulatory and Co-inhibitory molecules
Engagement of the TCR in the absence of this second co-stimulatory signal typically results in T cell anergy or apoptosis.
In addition, T cell activation can be negatively regulated by co-inhibitory molecules present on APCs. Therefore,
integration of the signals transduced by co-stimulatory and co-inhibitory molecules following TCR engagement directs
the outcome and magnitude of a T cell response including the enhancement or suppression of T cell proliferation,
differentiation, and/or cytokine secretion.
A Quick Glance at Key Types of T Cell Co-Signaling
Kind reminder: If you are interested in any other targets, please visit our website or contact us.
(Chen and Flies, 2013, Nat Rev Immunol)
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Antibodies for
T Cell Co-Signaling
Research
4. Popular antibodies for Ig Superfamily
Many of Ig suprfamily molecules are being investigated as potential therapeutic targets for cancer immunotherapy,
since they have shown anti-tumor activity via immunity pathways. Creative Biolabs provides antibodies to help
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value for a wide range of applications and specific assays.
Targets Clone Applications Species reactivity Cat.No.
B7-1/ CD80
6N36 F, IH, N, WB Human CBMAB-C8378-LY
2E5 IC/IF, IH, P, WB Human CBMAB-C5006-LY
1E2F10 E, C, WB Human, Mouse, Pig CBMAB-C3931-LY
B7-2/ CD86
IT2.2 F, FN Human CBMAB-C4995-CQ
GL1 F, IF, IH, IP Mouse CBMAB-C3032-CQ
CBFYC-1466 F, IH, IP, WB Human CBMAB-C1524-FY
B7-H1/ PD-L1 10F.9G2 B Mouse CBMAB-1081-LY
B7-H2/ ICOS L HK5.3 N Mouse CBMAB-1021-LY
B7-H3 MJ18 B, F Mouse CBMAB-0957-LY
B7-H5/ VISTA/
PD-1H
MH5A F Mouse CBMAB-P3787-YC
MIH63 F Mouse CBMAB-V0191-LY
MM0741-29N17 WB Human CBMAB-G6682-LY
B7-H7/ HHLA2
CBYY-1762 B, IC, F Human CBMAB-2111-YY
CBFYH-1066 WB Mouse, Rat, Human CBMAB-H2010-FY
CBYY-1764 F, MC Human CBMAB-2113-YY
BTLA
4D6 WB, IC/IF Human CBMAB-C6797-LY
PJ196 B, A, F Mouse CBMAB-0961-LY
CBYY-0904 WB, IH
Human, Mouse, Rat,
Monkey, Dog
CBMAB-0907-YY
CD28
CD28.2 WB, F, IH, IF, C Human, Primate CBMAB-C0532-CQ
1D5 E, WB Human CBMAB-C3842-LY
204.12 F, IH, C, MC Human, Mouse CBMAB-C0581-LY
CD28H/
IGPR-1
CBYJT-3537 WB, IP, IF, E Human CBMAB-T2862-YJ
CBYJT-3536 F, MC Human CBMAB-T2861-YJ
CBYJT-3535 F, IH, MC Human CBMAB-T2860-YJ
CTLA-4
BN13 N, F Human CBMAB-0932-LY
CBXC-2930 WB, F, E, IF Human, Mouse CBMAB-C0234-CQ
9D9 N, WB Mouse CBMAB-1009-LY
ICOS
CBYY-I0795 E, F, N, WB Human CBMAB-I1772-YY
27A12 F, IH, FN, IP, C Mouse CBMAB-I0231-YY
CBYY-C0578 F, FN, N, B mouse CBMAB-C1820-YY
PD-1
J116 N, B Human CBMAB-0943-LY
J110 F Human CBMAB-0942-LY
PD-L2/ B7-DC TY25 B Mouse CBMAB-1082-LY
Antibodies for B7/CD28 Families
To be continued.
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Antibodies for
T Cell Co-Signaling
Research
5. To be continued.
Antibodies for Butyrophilins
Targets Clone Applications Species reactivity Cat.No.
BTN1A1/
Butyrophilin
4A11 WB Human CBMAB-0023-YC
CBYY-0907 F, IF, WB Human CBMAB-0910-YY
CBYY-0908 IF, WB Human, Dog, Rat, Monkey CBMAB-0911-YY
BTN2A1 CBYY-0920 F Human CBMAB-0923-YY
BTN3A1/
CD277
BT3.1 F Human CBMAB-C0440-CQ
CBXC-1338 F Human CBMAB-C1606-CQ
CBYY-0921 F, IP Human CBMAB-0924-YY
BTNL2/Butyro
philin-like 2
CBYY-0924 WB Human CBMAB-0927-YY
CBYY-0923 IH, WB Human CBMAB-0926-YY
Antibodies for Nectin and Nectin-like Binding Receptors
Targets Clone Applications Species reactivity Cat.No.
CD96
NK92.39 F, FN Human CBMAB-C4981-CQ
6A6 F, FN, IA, WB Mouse CBMAB-C1575-YY
CBXC-1661 E, F, WB Mouse CBMAB-C2947-CQ
CD155/ PVR
D171 F, FN, IF Human, Monkey CBMAB-P3545-YC
CBFYC-3071 E, WB, IP Human CBMAB-C3148-FY
3F1 F, FN Mouse CBMAB-C0326-YY
CRTAM
21A9 C, WB Human CBMAB-C4398-LY
CBXC-2516 WB, F Human CBMAB-C0923-CQ
CBFYC-2236 E Human CBMAB-C2306-FY
DNAM-1/
CD226
1X20 WB, P, B, N Human CBMAB-D0066-YC
DX11 F, FN, IP Human CBMAB-D0067-YC
CBYCD-529 E, WB Mouse CBMAB-D0070-YC
Nectin-2/
CD112
13A61 E, F, C, IP, WB Mouse CBMAB-P0546-YC
CBWJN-0430 E, F, IH, IP, WB Human, Mouse CBMAB-N1731-WJ
11E1 WB, E, IP Mouse CBMAB-C2426-LY
Nectin-3/
CD113
N3.12.4 FM, IC, IPP Human CBMAB-N1740-WJ
103-A1 E, F, IH, IP, WB Mouse CBMAB-N1737-WJ
1D1 E, WB Human CBMAB-P0552-YC
TIGIT
1G9 F Mouse CBMAB-1097-LY
CBYJT-3141 F, MC Human CBMAB-T2412-YJ
CBYJT-3146 F Mouse CBMAB-T2417-YJ
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Antibodies for
T Cell Co-Signaling
Research
6. To be continued.
Antibodies for SLAM Family
Targets Clone Applications Species reactivity Cat.No.
2B4/
CD244/
SLAMF4
2B4.69 F, P Human CBMAB-1865CQ
CBLQC-001 WB, EC, P Human CBMAB-2045CQ
7D24 WB Human CBMAB-C8620-LY
CD48/
SLAMF2
3H1461 F, IF, C, WB Human, Monkey CBMAB-C1176-LY
7H198 E, C, WB Human CBMAB-C8807-LY
CBYY-C1477 E, IC, WB Goat, Human CBMAB-C2915-YY
CD58/
LFA-3
2D11-B10 E, IF, P, WB Human CBMAB-C4867-LY
CBYJL-146
WB, IP, E, C, N, F, B, IC,
IF
Mouse, Human CBMAB-L0217-YJ
8G24 C, WB Human CBMAB-C9207-LY
SLAM/
CD150
SHM-57 F, IC, IF, C, IP Human CBMAB-S6564-CQ
CBXS-0418 E, F, IC, WB Human CBMAB-S3370-CQ
CBXC-1401 F Mouse CBMAB-C2631-CQ
Antibodies for TIM Family Receptors & Ligands
Targets Clone Applications Species reactivity Cat.No.
Galectin-3
15H199 IF, WB Cattle, Human, Mouse, Rat CBMAB-G6225-LY
CBYJL-1522 E, IF, IH, WB, siRNA Human, Mouse, Rat CBMAB-L1288-YJ
4i288 E, IC, IF, IH, WB Human, Mouse, Rabbit, Rat CBMAB-G6241-LY
TIM-1/
KIM-1/
HAVCR
3F4 E, F, WB Human CBMAB-K0357-LY
RMT1-10 E, F, IF Mouse CBMAB-T0368-YJ
CBFYH-3519 WB, IC, P, C, E Human CBMAB-H4070-FY
TIM-3
8B.2C12 F, IH, IP Mouse CBMAB-C9049-LY
CBYY-C0698 F, IH, IP, FN Mouse CBMAB-C2051-YY
CBYJT-1358 F, IH, IP, WB Human CBMAB-T0377-YJ
TIM-4
CBYJT-3161 IA, IC, IF, FN Mouse CBMAB-T2435-YJ
RMT4-54 FN, P, IC, IF, F Mouse CBMAB-T2434-YJ
CBYJT-3155 E, IF, IP Human CBMAB-T2427-YJ
Creative Biolabs owns comprehensive antibody products and related services. Please contact us for more
detailed information and our team will get back to you as soon as possible. We are always here to serve you
the best to help promote your projects. The lists only exhibit a small part of our products. Please visit our
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Antibodies for
T Cell Co-Signaling
Research
7. Antibodies for Type V Subfamily Receptors & Ligands
Targets Clone Applications Species reactivity Cat.No.
4-1BB/
TNFRSF9/
CD137
CBFYC-0113 E, F, IC, IF Mouse CBMAB-C0130-FY
6D295 E, C, WB Mouse CBMAB-C8194-LY
4B4 (4B4-1) E, IP, F, FN
Human, Chimpanzee, Baboon,
Cynomolgus, Rhesus monkey
CBMAB-C0800-YY
4-1BB
Ligand/
TNFSF9
TKS-1 B Mouse CBMAB-0954-LY
014 E, F, IC/IF, IF Mouse CBMAB-C0047-LY
CBYJT-4018 E, F, FN, WB Human CBMAB-T3432-YJ
CD27/
TNFRSF7
LG.8A6 E, F, IP Mouse CBMAB-C3424-CQ
LG.7F9 F, IP, FN Human, Mouse, Rat CBMAB-C0809-CQ
1C1G3 E, IF, C, WB Human CBMAB-C3719-LY
CD27
Ligand/
TNFSF7
BU69 F, IC, C, IP Human CBMAB-C2438-CQ
7H173 E, F, IC, IH Human CBMAB-C8792-LY
14L233 E, N Mouse CBMAB-C3128-LY
CD30/
TNFRSF8
15B3 IC/IF, C, P Human CBMAB-C3254-LY
3B10 F, E, WB Human CBMAB-C5681-LY
CBYJT-3877 P, IF, IC, F Human CBMAB-T3272-YJ
CD30
Ligand/
TNFSF8
3G56 WB Human CBMAB-C6161-LY
CBYJT-4014 F, IH, FN, IP Mouse CBMAB-T3427-YJ
CBYJT-4010 E, WB Human CBMAB-T3423-YJ
GITR/
TNFRSF18
7C13 P, F Mouse CBMAB-G6637-LY
CBYJT-3773 E, WB, IH Human, Mouse CBMAB-T3156-YJ
CBFYC-3173 ED, E F, N, WB Human CBMAB-C3250-FY
GITR
Ligand/
TNFSF18
CBYJT-3971 F, N Human CBMAB-T3383-YJ
6D415 E, F Mouse CBMAB-G6651-LY
CBYJT-3987 E, F, WB Mouse CBMAB-T3399-YJ
OX40/
TNFRSF4
CBXO-0487 F, IH, C, MC Mouse CBMAB-O0896-CQ
7D6 F, WB Cat, Human CBMAB-O0015-CQ
CBXO-0385 WB, F, MC Human CBMAB-O0039-CQ
OX40
Ligand/
TNFSF4
CBYJT-3998 F, FN, IP, WB Mouse CBMAB-T3411-YJ
CBYJT-3991 IH, FN, F, N Human CBMAB-T3404-YJ
OX89 F, FN, IH Mouse CBMAB-O0081-CQ
Popular antibodies for TNF Superfamily
Like Ig superfamily, TNF superfamily is also investigated as potential targets for cancer immunotherapy, which
consists of type V and type L subfamily receptors and ligands. Creative Biolabs provides antibodies to help facilitate
your T cell co-signaling research within budget requirements, increasing efficiency and offering the best value for a
wide range of applications and specific assays.
To be continued.
info@creative-biolabs.com www.antibody-creativebiolabs.com
06
Antibodies for
T Cell Co-Signaling
Research
8. Antibodies for
T Cell Co-Signaling
Research
Antibodies for Type L Subfamily Receptors & Ligands
Targets Clone Applications Species reactivity Cat.No.
CD160
4 IP, F Human CBMAB-C1175-FY
CNX46-3 F, WB Rat CBMAB-N4376-WJ
1D4B IC Mouse CBMAB-N0646-WJ
LAIR1
2G4 E, WB Human CBMAB-C5185-LY
Plc12AT E, WB, IF Human CBMAB-L0498-YJ
CBYJL-2416 E Mouse CBMAB-L2744-YJ
Targets Clone Applications Species reactivity Cat.No.
CD40/
TNFRSF5
G28.5 F, IH, IP, MC Human CBMAB-C0673-CQ
3B2 E, C, WB Human CBMAB-C5702-LY
1C10 F, C, IP Mouse CBMAB-C0485-LY
CD40
Ligand/
TNFSF5
TNFSF5 B Mouse CBMAB-0969-LY
DR3/
TNFRSF25
11H6L9 F, IC, IF, WB Human, Mouse CBMAB-D2329-YC
4C12 AG, F Mouse CBMAB-D2331-YC
7H65 E, IH, WB Mouse CBMAB-D2334-YC
HVEM/
TNFRSF14
Laury-1 F, IC, IF, IP Human CBMAB-T3128-YJ
CBFYH-2797 WB, F, MC, EC Human CBMAB-H0058-FY
7H150 E, F Human CBMAB-C8777-LY
LIGHT/
TNFSF14
CBYJL-2374 WB, IP, IF, P, E Human CBMAB-L2683-YJ
15B2 E, IP Mouse, Human CBMAB-C3247-LY
CBYJT-3949 E, IC, IH, WB Human CBMAB-T3356-YJ
TL1A/
TNFSF15
Tingo-1 E, IP, WB Mouse CBMAB-T3380-YJ
TLRM1-1 WB, P, IF, IC, F Human CBMAB-T3374-YJ
CBYJT-3957 WB, B, N Human CBMAB-T3364-YJ
Antibodies for Others
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9. Antibody Services Guidance
Specific
Yes
What's my target?
Popular
Catalogue Ab Custom Ab
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Suit my project
Available or not in Creative Biolabs?
Order the Catalogue Ab Online
Test the Ab
Mouse or rabbit?
Specific epitope
Batch to batch reproducibility
Monoclonal Ab Polyclonal Ab
Epitope synthesis or not?
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Antibodies for
T Cell Co-Signaling
Research
10. Innovative technologies and ideas
Numerous worldwide customers
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High efficiency and short turnaround time
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With extensive experience and over a decade superior antibody services for numerous
worldwide customers, Creative Biolabs has blossomed into a service leader in the field of
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Antibodies for
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Research
Custom Antibody Service Process
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Submit protein
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