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Kimberlyanne Morales
What is Tourette
syndrome?
 A disorder characterized by recurring
  and involuntary movements or sounds
  called tics.
 There are two types of tics: motor and
  vocal. Motor tics are uncontrolled body
  movements and vocal tics are outbursts
  of sound.
 In 1886, a French physician named
  Gilles de la Tourrete discovered Tourette
  syndrome.
Other Names
 TS
 Tourette's
  syndrome
 Gilles de la
  Tourette's
  Syndrome
  (GTS)
Mode of Inheritance
 Scientists believe that tics may result from
  changes in brain chemicals called
  neurotransmitters that are responsible for
  producing and controlling voluntary movements.
 Mutations involving the SLITRK1 gene on
  chromosome 13 have been identified in a small
  number of people with Tourette syndrome.
 Mutations have been reported in so few people
  with this condition that the association of the
  SLITRK1 gene has not been confirmed.
 Tourette’s may not even be a hereditary condition.
May Also Cause
   Deficit hyperactivity
    disorder (ADHD)
   Obsessive-
    compulsive disorder
    (OCD)
   Anxiety
   Depression
   Mood swings
   Sleep problems
Rate of Incidence
   Precise incidence is
    unsure, but it
    approximately
    affects 1 to 10 in
    1,000 children.
   It affects populations
    and ethnic groups
    globally.
   More common in
    males than in
    females.
Symptoms
   Tics can be simple or complex.
   Symptoms of simple motor tics: eye
    blinking, facial expressions expressing
    disgust, shoulder shrugging, and head jerking.
   Symptoms of simple vocal tics: repetitive throat-
    clearing, sniffing, or grunting sounds.
   Symptoms of complex motor tics: facial grimacing
    preceded by head jerking and a shoulder
    shrug, sniffing or touching
    objects, jumping, bending, twisting, and punching a
    person’s face.
   Symptoms of complex vocal tics: coprolalia
    (saying profane words) and echolalia (repetition of
    words or phrases of other people).
Progression
 Tics usually appear in childhood.
 Experience peak tic severity before
  the mid-teen years with improvement
  in the late teen years and early
  adulthood.
 Disorder is generally lifelong.
 Not life threatening; normal life
  expectancy.
Treatment
 Most people do not need medication for tic
  suppression.
 If the person is suffering from severe
  TS, there are medications to help such as
  Neuroleptics (used to treat psychotic and
  non-psychotic disorders). i.e. blocks
  receptors such as dopamine.
 Other medications such as clonidine and
  guanfacine (used for treating
  hypertension).
 There is no medication that will eradicate
  all the symptoms.
Detection
   Diagnosis is made after verifying that the
    patient has had both motor and vocal tics for
    at least 1 year.
   Existence of other neurological or psychiatric
    conditions can also help doctors arrive at a
    diagnosis.
   There are no blood, laboratory, or imaging
    tests needed for diagnosis.
   In rare cases, magnetic resonance imaging
    (MRI), computerized tomography (CT), and
    certain blood tests may be used to rule out
    other conditions that might be confused with
    TS.
Bibliography/References
   "Tourette Syndrome Fact Sheet." : National Institute
    of Neurological Disorders and Stroke (NINDS). Web.
    19 Apr. 2012.
    <http://www.ninds.nih.gov/disorders/tourette/detail_to
    urette.htm>.
   "MedicineNet.com." MedicineNet. Web. 19 Apr.
    2012.
    <http://www.medicinenet.com/tourette_syndrome/arti
    cle.htm>.
   Board, A.D.A.M. Editorial. "Causes, Incidence, and
    Risk Factors." Gilles De La Tourette Syndrome. U.S.
    National Library of Medicine, 18 Nov. 0000. Web. 19
    Apr. 2012.
    <http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH000
    1744/>.

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Tourettes

  • 2. What is Tourette syndrome?  A disorder characterized by recurring and involuntary movements or sounds called tics.  There are two types of tics: motor and vocal. Motor tics are uncontrolled body movements and vocal tics are outbursts of sound.  In 1886, a French physician named Gilles de la Tourrete discovered Tourette syndrome.
  • 3. Other Names  TS  Tourette's syndrome  Gilles de la Tourette's Syndrome (GTS)
  • 4. Mode of Inheritance  Scientists believe that tics may result from changes in brain chemicals called neurotransmitters that are responsible for producing and controlling voluntary movements.  Mutations involving the SLITRK1 gene on chromosome 13 have been identified in a small number of people with Tourette syndrome.  Mutations have been reported in so few people with this condition that the association of the SLITRK1 gene has not been confirmed.  Tourette’s may not even be a hereditary condition.
  • 5. May Also Cause  Deficit hyperactivity disorder (ADHD)  Obsessive- compulsive disorder (OCD)  Anxiety  Depression  Mood swings  Sleep problems
  • 6. Rate of Incidence  Precise incidence is unsure, but it approximately affects 1 to 10 in 1,000 children.  It affects populations and ethnic groups globally.  More common in males than in females.
  • 7. Symptoms  Tics can be simple or complex.  Symptoms of simple motor tics: eye blinking, facial expressions expressing disgust, shoulder shrugging, and head jerking.  Symptoms of simple vocal tics: repetitive throat- clearing, sniffing, or grunting sounds.  Symptoms of complex motor tics: facial grimacing preceded by head jerking and a shoulder shrug, sniffing or touching objects, jumping, bending, twisting, and punching a person’s face.  Symptoms of complex vocal tics: coprolalia (saying profane words) and echolalia (repetition of words or phrases of other people).
  • 8.
  • 9. Progression  Tics usually appear in childhood.  Experience peak tic severity before the mid-teen years with improvement in the late teen years and early adulthood.  Disorder is generally lifelong.  Not life threatening; normal life expectancy.
  • 10. Treatment  Most people do not need medication for tic suppression.  If the person is suffering from severe TS, there are medications to help such as Neuroleptics (used to treat psychotic and non-psychotic disorders). i.e. blocks receptors such as dopamine.  Other medications such as clonidine and guanfacine (used for treating hypertension).  There is no medication that will eradicate all the symptoms.
  • 11.
  • 12. Detection  Diagnosis is made after verifying that the patient has had both motor and vocal tics for at least 1 year.  Existence of other neurological or psychiatric conditions can also help doctors arrive at a diagnosis.  There are no blood, laboratory, or imaging tests needed for diagnosis.  In rare cases, magnetic resonance imaging (MRI), computerized tomography (CT), and certain blood tests may be used to rule out other conditions that might be confused with TS.
  • 13. Bibliography/References  "Tourette Syndrome Fact Sheet." : National Institute of Neurological Disorders and Stroke (NINDS). Web. 19 Apr. 2012. <http://www.ninds.nih.gov/disorders/tourette/detail_to urette.htm>.  "MedicineNet.com." MedicineNet. Web. 19 Apr. 2012. <http://www.medicinenet.com/tourette_syndrome/arti cle.htm>.  Board, A.D.A.M. Editorial. "Causes, Incidence, and Risk Factors." Gilles De La Tourette Syndrome. U.S. National Library of Medicine, 18 Nov. 0000. Web. 19 Apr. 2012. <http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH000 1744/>.