ThriveAbility is an approach that integrates strategy, innovation, sustainability and design to help business leaders change their goals, rules, and approach to catalyze sustainable growth. It describes emerging best practices and provides a framework to calculate costs/benefits of different options. The document outlines the challenges of transitioning from the current economic system to a new model that recognizes environmental limits and prioritizes human well-being over profits. It argues that top leaders must embrace this transition through ThriveAbility in order to realize trillion dollar business opportunities in creating a sustainable future.