The opioid epidemic has become a public health crisis in recent years. Factors that increase the risk of opioid misuse include experiencing physical or social hardships, mental health issues, substance use, and criminal activity. Opioids are both legal and illegal drugs, including prescription medications like oxycodone and hydrocodone as well as heroin. Addiction is driven by biological changes in the body and brain that occur quickly after regular opioid use. Prevention through education is key to addressing this epidemic and reducing stigma around addiction.