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Physiology of the Male Sexual
Act
Leul Biruk
MD 014/15
Myungsung Medical college
Introduction
 The Human Sexual Response is classified into four phases
1.Excitement
2.Plateu
3.Orgasim
4. Resolution
3/17/2017
2
coitus and CAD
Introduction
1.Excitement
 An increase in muscle tone (myotonia) of
certain muscle groups.
 An increase in breathing rate , heart rate and
blood pressure .
 Flushed skin (vasocongestion )
 Erection of the man's penis, scrotal sac
thickens, elevates
3/17/2017
3
coitus and CAD
Introduction
2. Plateau
 Increased sexual pleasure with increased
stimulation, and further increased muscle
tension.
 Breathing rate continues at an elevated level.
 Copious perspiration
 Increased myotonia
 Both males and females continue
vasocongestion to max
 Cowper’s glands secrete fluid through tip of
penis: may contain live sperm!
 scrotum even higher and testicles bigger
3/17/2017coitus and CAD
4
Introduction
3. Orgasm
 The shortest phase of the sexual
response cycle, typically lasting only
several seconds.
 Heart rate and blood pressure increases
maximally.
 contraction of seminal vesicles,
vas and prostate
 contraction of urethra and penis:
ejaculation
3/17/2017
6
coitus and CAD
Introduction
4 . Resolution
 Begins immediately after orgasm.
 Allows the muscle to relax.
 The body returns to its original, non excited
state.
 Blood pressure and heart rate drop.
3/17/2017
8
coitus and CAD
Nervous control of the male sexual cycle
 Sensory input from the genital tract is carried by the
pudendal nerve to the S2–S4 segment of the spinal
cord.
 The somatic motor fibers -S2–S4 and supply the
pelvic floor muscles and the external anal sphincter.
 Descending parasympathetic innervation exits the
spinal cord at the S2–S4 level and reaches the penis.
 It is responsible for the corporeal vasodilatation and
corporeal smooth muscle relaxation, and hence the
penile transformation from the flaccid to the erect
state.
 The sympathetic innervation exits the spinal cord at
T11–L2 level and reaches the penis.
 It is responsible for the emission and ejaculation
through coordinated contractions of the vas
deferens, ampulla, seminal vesicles, prostate, and the
bladder neck.
Stimulation
 Mechanisms of stimulation
psychic stimulation from the brain
actual sexual stimulation from the sex organs
usually it is a combination of both.
 Glans Penis - most important source of sensory nerve
signals for initiating the male sexual act
 Areas adjacent to the penis - stimulation of the anal
epithelium, the scrotum
 Psychic Element of Male Sexual Stimulation:
 Thinking sexual thoughts dreaming that the act of
intercourse is being performed can initiate the male
act, culminating in ejaculation.
Eg. nocturnal emissions during the teens.
 Increased inflow and blocked outflow
 impulses in afferents from the genitalia and
descending tracts that mediate erection in response
to erotic psychological stimuli. (integrating centers in
LS)
 The efferent parasympathetic fibers are in the pelvic
splanchnic nerves (nervi erigentes).
 The fibers presumably release acetylcholine and
the vasodilator vasoactive intestinal
polypeptide (VIP)
 Nonadrenergic noncholinergic fibers are also present
in the nervi erigentes, and these contain large
amounts of nitric oxide synthase (NOS), the
enzyme that catalyzes
 NO activates soluble guanylyl cyclase, resulting in
increased production of cGMP
 PDE V
 Normally, erection is terminated by sympathetic
vasoconstrictor impulses to the penile arterioles
EJACULATION
 Sympathetic nervous system.
 Spinal cord reflex arc.
 Afferent pathways are mostly fibers from touch receptors in
the glans penis that reach the spinal cord through the
internal pudendal nerves.
 Considerable voluntary inhibitory control over this phase of
the sexual response.
 Two sequential processes.
 A) Emission - deposition of seminal fluid into the posterior
urethra. Simultaneous contractions of the ampulla of the vas
deferens, the seminal vesicles, and the smooth muscles of the
prostate
 B)True ejaculation -expulsion of the seminal fluid from
the posterior urethra through the penile meatus.
 Sympathetic innervation (the cord at T-12 to L-2) to
the genital organs through the hypogastric and pelvic
sympathetic nerve plexuses to initiate emission.
 contractions of the prostate gland followed by
contraction of the seminal vesicles expel prostatic
and seminal fluid – urethra
 Male Orgasm=The entire period of
emission and ejaculation
Disorders with Ejaculation
 Premature Ejaculation
 a male sexual dysfunction characterized by ejaculation which
always or nearly always occurs prior to or within about one
minute of vaginal penetration; and, inability to delay
ejaculation on all or nearly all vaginal penetrations
 Retrograde Ejaculation
 Sympathetic efferent fibers (T10-L3)
 During the expulsive phase, it is necessary that the bladder neck
(internal urethral sphincter) be closed to prevent the reflux of semen
into the bladder as the urethral pressure increases.
 Anejaculation
 inability to ejaculate semen despite stimulation of the penis by
intercourse or masturbation.
References
 Eric P. Widmaier, Hershel Raff, Kevin T. Strong
Vanders Human Physiology The Mechanisms of
Body Function 2008
 Medical Physiology - Prins. for Clin. Med. 4th ed. - R.
Rhoades, D. Bell (Lippincott, 2013)BBS
 Katzungs Basic & Clinical Pharmacology -13th 2015
THANK YOU
Leul Biruk
MD 014/15

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The male sexual act

  • 1. Physiology of the Male Sexual Act Leul Biruk MD 014/15 Myungsung Medical college
  • 2. Introduction  The Human Sexual Response is classified into four phases 1.Excitement 2.Plateu 3.Orgasim 4. Resolution 3/17/2017 2 coitus and CAD
  • 3. Introduction 1.Excitement  An increase in muscle tone (myotonia) of certain muscle groups.  An increase in breathing rate , heart rate and blood pressure .  Flushed skin (vasocongestion )  Erection of the man's penis, scrotal sac thickens, elevates 3/17/2017 3 coitus and CAD
  • 4. Introduction 2. Plateau  Increased sexual pleasure with increased stimulation, and further increased muscle tension.  Breathing rate continues at an elevated level.  Copious perspiration  Increased myotonia  Both males and females continue vasocongestion to max  Cowper’s glands secrete fluid through tip of penis: may contain live sperm!  scrotum even higher and testicles bigger 3/17/2017coitus and CAD 4
  • 5.
  • 6. Introduction 3. Orgasm  The shortest phase of the sexual response cycle, typically lasting only several seconds.  Heart rate and blood pressure increases maximally.  contraction of seminal vesicles, vas and prostate  contraction of urethra and penis: ejaculation 3/17/2017 6 coitus and CAD
  • 7.
  • 8. Introduction 4 . Resolution  Begins immediately after orgasm.  Allows the muscle to relax.  The body returns to its original, non excited state.  Blood pressure and heart rate drop. 3/17/2017 8 coitus and CAD
  • 9. Nervous control of the male sexual cycle  Sensory input from the genital tract is carried by the pudendal nerve to the S2–S4 segment of the spinal cord.  The somatic motor fibers -S2–S4 and supply the pelvic floor muscles and the external anal sphincter.
  • 10.  Descending parasympathetic innervation exits the spinal cord at the S2–S4 level and reaches the penis.  It is responsible for the corporeal vasodilatation and corporeal smooth muscle relaxation, and hence the penile transformation from the flaccid to the erect state.
  • 11.  The sympathetic innervation exits the spinal cord at T11–L2 level and reaches the penis.  It is responsible for the emission and ejaculation through coordinated contractions of the vas deferens, ampulla, seminal vesicles, prostate, and the bladder neck.
  • 12.
  • 13. Stimulation  Mechanisms of stimulation psychic stimulation from the brain actual sexual stimulation from the sex organs usually it is a combination of both.
  • 14.  Glans Penis - most important source of sensory nerve signals for initiating the male sexual act  Areas adjacent to the penis - stimulation of the anal epithelium, the scrotum  Psychic Element of Male Sexual Stimulation:  Thinking sexual thoughts dreaming that the act of intercourse is being performed can initiate the male act, culminating in ejaculation. Eg. nocturnal emissions during the teens.
  • 15.
  • 16.  Increased inflow and blocked outflow  impulses in afferents from the genitalia and descending tracts that mediate erection in response to erotic psychological stimuli. (integrating centers in LS)  The efferent parasympathetic fibers are in the pelvic splanchnic nerves (nervi erigentes).  The fibers presumably release acetylcholine and the vasodilator vasoactive intestinal polypeptide (VIP)
  • 17.  Nonadrenergic noncholinergic fibers are also present in the nervi erigentes, and these contain large amounts of nitric oxide synthase (NOS), the enzyme that catalyzes  NO activates soluble guanylyl cyclase, resulting in increased production of cGMP  PDE V  Normally, erection is terminated by sympathetic vasoconstrictor impulses to the penile arterioles
  • 18.
  • 19.
  • 20. EJACULATION  Sympathetic nervous system.  Spinal cord reflex arc.  Afferent pathways are mostly fibers from touch receptors in the glans penis that reach the spinal cord through the internal pudendal nerves.  Considerable voluntary inhibitory control over this phase of the sexual response.  Two sequential processes.  A) Emission - deposition of seminal fluid into the posterior urethra. Simultaneous contractions of the ampulla of the vas deferens, the seminal vesicles, and the smooth muscles of the prostate  B)True ejaculation -expulsion of the seminal fluid from the posterior urethra through the penile meatus.
  • 21.
  • 22.
  • 23.
  • 24.  Sympathetic innervation (the cord at T-12 to L-2) to the genital organs through the hypogastric and pelvic sympathetic nerve plexuses to initiate emission.  contractions of the prostate gland followed by contraction of the seminal vesicles expel prostatic and seminal fluid – urethra  Male Orgasm=The entire period of emission and ejaculation
  • 25. Disorders with Ejaculation  Premature Ejaculation  a male sexual dysfunction characterized by ejaculation which always or nearly always occurs prior to or within about one minute of vaginal penetration; and, inability to delay ejaculation on all or nearly all vaginal penetrations  Retrograde Ejaculation  Sympathetic efferent fibers (T10-L3)  During the expulsive phase, it is necessary that the bladder neck (internal urethral sphincter) be closed to prevent the reflux of semen into the bladder as the urethral pressure increases.  Anejaculation  inability to ejaculate semen despite stimulation of the penis by intercourse or masturbation.
  • 26. References  Eric P. Widmaier, Hershel Raff, Kevin T. Strong Vanders Human Physiology The Mechanisms of Body Function 2008  Medical Physiology - Prins. for Clin. Med. 4th ed. - R. Rhoades, D. Bell (Lippincott, 2013)BBS  Katzungs Basic & Clinical Pharmacology -13th 2015