The document discusses the Diabetes Health Profile (DHP), a patient-reported outcome measure that assesses health-related quality of life for people over 18 with diabetes. It measures psychological distress, barriers to activity, eating behaviors, and mood. There are two versions - a 32-item and 18-item version. Items are scored on a scale and standardized to evaluate dysfunction. The DHP has established validity and reliability and can be used to measure the impact of health programs and treatment effectiveness on patients' quality of life. It is available in 29 languages and has been used internationally in clinical trials and research.

1. The Diabetes Health Profile (DHP-1 & DHP-18) Dr Keith Meadows DHP Research & Consultancy Ltd Copyright DHP Research & Consultancy Ltd 2011 All rights reserved

2. A diabetes-specific patient reported outcome measure (PROM) of the health-related quality of life (HRQoL) of people 18 years and older. Completed globally by over 8,000 patients including the UK and Europe, it is available in 29 different languages. What is the Diabetes Health Profile? Copyright DHP Research & Consultancy Ltd 2011 All rights reserved

3. What does the DHP measure? Psychological distress Barriers to activity Disinhibited eating Dysphoric mood, irritability, feelings of hopelessness Anxiety, perceived barriers in activity Lack of eating restraint, eating in response to food cues.

4. There are two versions of the DHP DHP-1 32-items DHP-18 18-items Type 1 Diabetes and insulin requiring Type 1 and Type 2 Diabetes including, tablet, diet

5. How is the DHP scored? Items scored using 4-point Likert scale (Range 0-3) Standardised subscale scores 0 (no dysfunction) thru 100 (max dysfunction) Norm-referenced scoring using standardised population means

6. The DHP is a reliable and valid measure of diabetes HRQoL Established content validity based on patient interviews and sound conceptual model Psychometrically proven conceptual framework Consistent factor structure across samples and patient groups, Low ceiling and floor effects, high item convergent and discriminant validity and construct validity High Cronbach’s alpha internal reliability coefficients Psychometrics Discriminates between patients groups treated with insulin, oral treatment and diet, presence of microvascular complications, weight gain, non-adherence to treatment, severe hypoglycaemic episodes, age, sex Minimally Important difference (MID) values Predicts both the EQ-5D and SF-6D utility scores Proven patient acceptability, high item completion rate (90%) Flesch reading ease >75 Clinical utility

7. The DHP can be used for: Measuring the effect of health improvement on the patient’s HRQoL Evaluating the impact of health programmes on the patient’s HRQoL Assessing treatment effectiveness on the patient’s HRQoL Improving doctor/patient communication and the patient’s HRQoL Monitoring patients HRQoL

8. Current use of the DHP International clinical trials International/national research National community-based surveys Service design and development

9. Administering the DHP Images & copy courtesy of PHT Corporation. Copyright 2011 PHT Corporation. All rights reserved In addition to pencil/paper format the DHP can be administered using a variety of e-devices

10. The eDHP-18 PHT LogPad LV PHT SitePad

11. Translations . Bulgarian Canada (English) Canada (French) Croation Czech Danish Finnish Flemish French French (Swiss) German German (Austrian) German (Swiss) Hungarian Italian Italian (Swiss) Languages Mandarin Netherlands Norwegian Polish Romanian Slovak Slovenian Spanish Swedish US (English) US (Spanish) Turkish (for Germany) Waloon

12. DHP Research & Consultancy Ltd 113 Lower Camden Chislehurst Kent BR7 5JD Tel: +44 (0)20 8467 3739 Email: kmeadows@dhpresearch.com Website: www.dhpresearch.com Copyright DHP Research & Consultancy Ltd 2011 All rights reserved