Simply applying knowledge we have reliably in hand, we could prevent fully 80% of all chronic disease and premature death in modernized and modernizing countries. Standing between us and that prize is an obstacle course of competing claims, false promises, and profit-driven, pop culture nonsense. The case will be made for True Health Coalition to rally diverse voices to the cause of using what we know, even as we pursue what we do not. The challenges, operations, and promise of the endeavor will be discussed.
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The Case For a True Health Coalition
1. The Case for a True Health Coalition
…if not us, WHO?
David L. Katz, MD, MPH, FACPM, FACP
Director, Prevention Research Center
Yale University
President, American College of Lifestyle Medicine
Director, Integrative Medicine Center, Griffin Hospital
Editor-in-Chief, Childhood Obesity
Author, Disease Proof
UCONN
3-3-15
3. Beyond the bits; there is Lifestyle… and
everything else
McGinnis JM, Foege WH. Actual causes of death in the United States. JAMA.
1993;270:2207-12
Mokdad AH, Marks JS, Stroup DF, Gerberding JL. Actual causes of death in the
United States, 2000. JAMA. 2004;291:1238-45
4. The People in Potsdam-
Ford ES, Bergmann MM, Kröger J, Schienkiewitz A,
Weikert C, Boeing H. Healthy living is the best revenge:
findings from the European Prospective Investigation
Into Cancer and Nutrition-Potsdam study. Arch Intern
Med. 2009 Aug 10;169(15):1355-62
Or the UK:
Kvaavik E, Batty GD, Ursin G, Huxley R, Gale CR. Influence of individual and combined
health behaviors on total and cause-specific mortality in men and women: the United
Kingdom health and lifestyle survey. Arch Intern Med. 2010;170:711-8
Or the US
McCullough ML, Patel AV, Kushi LH, Patel R, Willett WC, Doyle C, Thun MJ, Gapstur SM.
Following cancer prevention guidelines reduces risk of cancer, cardiovascular disease, and
all-cause mortality. Cancer Epidemiol Biomarkers Prev. 2011;20:1089-97
5. Fresher still-
Akesson A, Larsson SC, Discacciati A, Wolk A. Low-
Risk Diet and Lifestyle Habits in the Primary
Prevention of Myocardial Infarction in Men: A
Population-Based Prospective Cohort Study. J Am
Coll Cardiol. 2014 Sep 30;64(13):1299-306
6. Fresher-er…
Aleksandrova K, et al. Combined impact of healthy
lifestyle factors on colorectal cancer: a large
European cohort study. BMC Med. 2014 Oct
10;12(1):168. [Epub ahead of print]
7. Fresher-er-er…
Chomistek AK, Chiuve SE, Eliassen AH, Mukamal KJ,
Willett WC, Rimm EB. Healthy lifestyle in the
primordial prevention of cardiovascular disease
among young women. J Am Coll Cardiol. 2015 Jan
6;65(1):43-51
8. rePercussions…
…to our pith and marrow; the case for nurturing nature:
Ornish D, Magbanua MJ, Weidner G, Weinberg V, Kemp C, Green C, Mattie MD,
Marlin R, Simko J, Shinohara K, Haqq CM, Carroll PR. Changes in prostate gene
expression in men undergoing an intensive nutrition and lifestyle intervention.
Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8369-74
Hietaniemi M, Jokela M, Rantala M, Ukkola O, Vuoristo JT, Ilves M, Rysä J, Kesäniemi Y. The effect of
a short-term hypocaloric diet on liver gene expression and metabolic risk factors in obese women.
Nutr Metab Cardiovasc Dis. 2009 Mar;19(3):177-83
Freedland SJ, Aronson WJ. Dietary intervention strategies to modulate prostate cancer risk and
prognosis. Curr Opin Urol. 2009 May;19(3):263-7
10. Lost in translation…
Knowledge, alas, isn’t power…
Katz DL. Life and death, knowledge and power:
why knowing what matters isn’t what's the
matter. Arch Intern Med. 2009 Aug 10;169(15):1362-3
11. Obesity Trends* Among U.S. Adults
BRFSS, 1985
(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)
No Data <10% 10%–14%
12. Obesity Trends* Among U.S. Adults
BRFSS, 1995
(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)
No Data <10% 10%–14% 15%–19%
13. Obesity Trends* Among U.S. Adults
BRFSS, 2010
(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person)
No Data <10% 10%–14% 15%–19% 20%–24% 25%–29% ≥30%
14. 15%–<20 20%–<25% 25%–<30% 30%–<35% ≥ 35%
Prevalence* of Self-Reported Obesity Among U.S. Adults
by State and Territory, BRFSS, 2013
*Prevalence estimates reflect BRFSS methodological changes started in 2011. These estimates should not be
compared to prevalence estimates before 2011.
CA
MT
ID
NV
UT
AZ
NM
WY
WA
OR
CO
NE
ND
SD
TX
OK
KS
IA
MN
AR
MO
LA
MI
IN
KY
IL
OH
TN
MS AL
WI
PA
WV
SC
VA
NC
GA
FL
NY
VT
ME
HI
AK
NH
MA
RI
CT
NJ
DE
MD
DC
PRGUAM
15. Age-adjusted Percentage of U.S. Adults Who Had
Diagnosed Diabetes
<4.5%Missing data
4.5 - 5.9% 6.0 - 7.4%
7.5 - 8.9% ≥9.0%
CDC’s Division of Diabetes Translation. National Diabetes Surveillance System
available at http://www.cdc.gov/diabetes/statistics
1994
16. Age-adjusted Percentage of U.S. Adults Who Had
Diagnosed Diabetes
<4.5%Missing data
4.5 - 5.9% 6.0 - 7.4%
7.5 - 8.9% ≥9.0%
CDC’s Division of Diabetes Translation. National Diabetes Surveillance System
available at http://www.cdc.gov/diabetes/statistics
2010
17. From the frying pan…
http://www.pophealthmetrics.com/content/8/1/29
Projection of the year 2050 burden of diabetes in the US
adult population: dynamic modeling of incidence,
mortality, and prediabetes prevalence
One-Third of U.S. Adults Could Have Diabetes by 2050:
CDC 'Alarming numbers' point to importance of healthier lifestyles in reversing the
trend, experts say
HealthDay News, October 22, 2010
By 2050, between one-fifth and one-third of all adults could have diabetes -- with virtually all the
increase attributed to type 2 diabetes, which is largely preventable.
U.S. Diabetes Rates Soaring: CDC
Numbers have doubled over 15 years across
18 states, and all states now have rates of 6
percent or more
By Steven Reinberg
HealthDay Reporter
Last Updated: Nov. 15, 2012
Masters RK, Reither EN, Powers DA, Yang
YC, Burger AE, Link BG. The Impact of
Obesity on US Mortality Levels: The
Importance of Age and Cohort Factors in
Population Estimates. Am J Public Health.
2013 Aug 15. [Epub ahead of print]
Dabelea D, Mayer-Davis EJ, Saydah S, Imperatore G, Linder B, Divers J, Bell
R, Badaru A, Talton JW, Crume T, Liese AD, Merchant AT, Lawrence JM,
Reynolds K, Dolan L, Liu LL, Hamman RF; SEARCH for Diabetes in Youth
Study. Prevalence of type 1 and type 2 diabetes among children and
adolescents from 2001 to 2009. JAMA. 2014 May 7;311(17):1778-86
Diabetes in young people up 30% to 35% in past decade
By Steven Ross Johnson
May 6, 2014
18. Cooked?
40 Percent of Americans Will Develop
Diabetes, CDC Projects
Rates for black women and Hispanics even higher
at 50 percent
By Dennis Thompson
HealthDay Reporter
TUESDAY, Aug. 12, 2014 (HealthDay News) –
Aug. 13, 2014, The Lancet Diabetes & Endocrinology, online
19. The Writing is on the Wall-
November 12, 2008
Child Obesity Seen as Warning of Heart Disease
By PAM BELLUCK
February 10, 2011, 2:27 pm
Stroke Rising Among Young People
By TARA PARKER-POPE
21. What lifestyle can do…
80% reduction in heart disease
90% reduction in diabetes
60% reduction in cancer
and so on…
4 Healthy lifestyle factors help ward off chronic disease. Diet, exercise, low body mass index and not smoking
can reduce the incidence of heart disease, diabetes, stroke and cancer. Duke Med Health News. 2009;15:4-5
Knoops KT, de Groot LC, Kromhout D, Perrin AE, Moreiras-Varela O, Menotti A, van Staveren WA.
Mediterranean diet, lifestyle factors, and 10-year mortality in elderly European men and women: the HALE
project. JAMA. 2004;292:1433-9
22. The Public-
in private parts…
Katz DL. Facing the facelessness of public health:
what’s the public got to do with it? Am J Health
Promotion. 2011 Jul-Aug;25(6):361-2
30. When clear where “there” is-
(Can We Say What Diet Is "Best"? David L. Katz; Huffington Post, 9/7/11:
http://www.huffingtonpost.com/david-katz-md/best-diets_b_950672.html)
-it may still seem…
you can’t get there from here:
31. …& the other problem:
Is it clear where “there” is?
34. Bird’s (Katz’?) eye view-
Katz DL et al. Can we say what diet is best for
health? Annu Rev Public Health. 2014 Mar 18; 35:83-
103
Science Compared Every Diet, and the Winner Is Real Food
Researchers asked if one diet could be crowned best in terms of health outcomes.
If diet is a set of rigid principles, the answer is a decisive no. In terms of broader
guidelines, it's a decisive yes.
James Hamblin Mar 24 2014, 1:14 PM ET
Katz DL et al. Nutrition in Clinical Practice, 3rd
Edition. Wolters
Kluwer/Lippincott Williams & Wilkins. September, 2014
35. Other eyes, on the same prize -
Mann J et al. Low carbohydrate diets: going against the
grain. Lancet. 2014 Oct 25:384;1479-80
Ley SH, Hamdy O, Mohan V, Hu FB. Prevention and
management of type 2 diabetes: dietary components and
nutritional strategies. Lancet. 2014 Jun 7;383:1999-2007
Katz DL, Hu F. Knowing what to eat, refusing to swallow it. Huffington
Post. 7/2/14
36. Macronutrients, Misrepresentations, &
Mayhem-
Chowdhury R et al. Association of Dietary,
Circulating, and Supplement Fatty Acids With
Coronary Risk: A Systematic Review and Meta-
analysis. Ann Intern Med. 2014;160:398-406
Bazzano LA et al. Effects of low-carbohydrate
and low-fat diets: a randomized trial. Ann Intern
Med. 2014;161:309-318
38. “Eat food, not too much, mostly plants.”
-Michael Pollan
39. Much the same, in 572 pages…
Scientific Report of the 2015 Dietary
Guidelines Advisory Committee
http://www.health.gov/dietaryguidelines/2015-
scientific-report/
40. Mostly plants? Fuggedaboudit!...
Blanck HM, Gillespie C, Kimmons JE, Seymour JD, Serdula MK. Trends in
fruit and vegetable consumption among U.S. men and women, 1994-2005.
Prev Chronic Dis. 2008 Apr;5(2):A35. Epub 2008 Mar 15
Kimmons J, Gillespie C, Seymour J, Serdula M, Blanck HM. Fruit and
vegetablei ntake among adolescents and adults in the United States:
percentage meeting individualized recommendations. Medscape J Med.
2009;11(1):26. Epub 2009 Jan 26
Katz DL. Plant foods in the American diet? As we
sow... Medscape J Med.2009;11(1):25. Epub 2009
Jan 26
41.
42. EVEN when clear where “there” is-
(Can We Say What Diet Is "Best"? David L. Katz; Huffington Post, 9/7/11:
http://www.huffingtonpost.com/david-katz-md/best-diets_b_950672.html)
-it may seem…
you can’t get there from here:
51. The big spoon…
is culture.
Katz DL. Is obesity cultural? US News & World Report,
Eat + Run Blog; 10/4/12;
http://health.usnews.com/health-news/blogs/eat-
run/2012/10/04/is-obesity-cultural
54. GLiMMER: Vision
The Earth is both a beautiful Blue Planet, and a
universal Blue Zone
55. LiM
Global coalition of lifestyle medicine organizations;
ACLM as convener
Development, Refinement, Dissemination of best
practice models
Contributions to medical education (all levels)
Engagement of payers and policy makers to
advance reimbursement models
Participant in the True Health Coalition (aid, out)
Able to leverage cultural supports (aid, in)
57. LaM
Current Blue Zone Propagation Project
Dedicated “boots on the ground” supported by a
trust fund
Global coalition of lifestyle medicine experts
collaborating
Expert Evaluation
MTCT
PRCs
The True Health Coalition
58. Expert Evaluation
MTCT methodology:
Katz DL, Murimi M, Gonzalez A, Njike V, Green LW.
From controlled trial to community adoption: the
multisite translational community trial. Am J Public
Health. 2011 Aug;101(8):e17-27
PRC Network resources
26 academic research centers; devoted to CBPR
Other resources
59. The True Health Coalition
Designed to advance the #UseWhatWeKnow
principle
60.
61. The True Health Coalition
Academics
Journalists
Economists
Policy Makers / Government
Industry (e.g., food service; food manufacturers; fitness; health
technology)
Clinical Organizations (e.g., AMA; ACP; AHA; ACS; etc.)
Educational Organizations (e.g., AAMC; ACGME; etc.)
62. Ship & Sail, Wind & Wave
Project components are “ship & sail,” specific to a
given destination
The True Health Coalition generates a wind to fill
all sails by establishing consensus, repudiating
distractions and discord
63. Join us -
True Health Coalition
One Voice, United
A global voice devoted to disseminating and applying
what we know for sure about health promotion and
disease prevention.
Sign up today to become a member of the True Health
Coalition. Your voice matters!
sign me up!
http://glimmerinitiative.org/#coalition
68. Thank you!
David L. Katz, MD, MPH, FACPM, FACP
Director, Yale Prevention Research Center
President, Turn the Tide Foundation, Inc.
130 Division St.
Derby, CT 06418
(203) 732-1265
David.katz@yale.edu
www.davidkatzmd.com
Editor's Notes
Start with dark wood
Then, Kipling: stoicism/personal responsibility: just TREK through that forest…
Then ‘if, and but’- we are vulnerable, and succumb to forces greater than ourselves; any great storm: Sandy, Katrina
Forces creating epidemic obesity are a perfect storm
Still we might simply rely on personal responsibility to overcome them
Invictus: the case for overcoming all
But: Next Hill- forces can get the better of us
Tribune exposue
NY Times feature
Rick Letizia’s reference
New books on the topic of food engineered to overwhelm us
How to deal with that? Not just will power, but also skill power
The MINDSTREAM EXAMPLE (get data)
Then: skill power for all
Sandbag examples
The levee
The ultimate defense of the human body resides with the body politic
Donne…
-there is a veritable drum beat in the literature, percussing the promise of lifestyle to public health over and over…
-nor does this percussion stop at the surface of the drum- it reverberates to our innermost interstices- to our very genes…
-nature vs. nurture is a false divide; we can, in fact, nurture nature- and refashion our fate at the very level of our genes
-but knowledge is not power; the gap between what we know and do belies it
-there is a translational divide, a span of miles in between
-so, the road we follow to traverse those miles may make all the difference…
Methodology
The percent of U.S. adults who have diagnosed diabetes was determined by using data from the Behavioral Risk Factor Surveillance System (BRFSS, available at http://www.cdc.gov/brfss). An ongoing, yearly, state-based telephone survey of the non-institutionalized adult population in each state, the BRFSS provides state-specific information on behavioral risk factors for disease and on preventive health practices. Respondents who reported that a physician told them they had diabetes (other than during pregnancy) were considered to have diagnosed diabetes. Rates were age-adjusted using the 2000 U.S. Standard Population.
-and I ask you to help me prove it…
Demonstration
-we can, and must part the veil of statistical anonymity to see the faces- the faces of people we love- looking back. It is for them the bell tolls. It is for them the promises must be kept. It is because of them that there is and must be passion in the formula.
WHY section-
Even in an environment where humans have trouble surviving, polar bears are comfortable and at home-because it is the environment to which they are adapted, the one for which they are designed.
There are creatures adapted to this environment-and they are comfortable here. But the polar bear is not one of them!
Like polar bears burning beneath
Desert heat
We’re out of our bounds
With the things that we eat
Our adaptations are challenged
Our shrewdness on trial
Will we find our way home
Or stay lost in denial?
As we look forward, think what to do next
The past holds the answers in native context:
polar bears, zebras, giraffes and baboons
don’t ever sip tea, and never use spoons
Yet while saying nothing,
They tell us far more
About how to eat well
Than fad diets, galore!
The brazen claims of Atkins
And the siren song of Sears
Lie not along the way to eat
That’s stood the test of years
To promote healthful eating
Be not beguiled;
Put your ear to the past
Heed the call of the wild!
For our sea of dietary troubles, this displaced creature is an emblem…
but we’re much smarter than the average bear; unified against the rising tides of
dietary tribulation we may, by opposing, end them!
-either way, the metaphor I prefer is a levee; because we face a veritable obesigenic and morbidigenic flood tide
Flood:
-glow in the dark foods
-tsunami of marketing dollars
-wave after wave of labor-saving technology
-the scope of the flood may be summed up thus: throughout most of human history, calories were scarce and hard to get, and physical activity unavoidable; we have devised a modern world in which physical activity is scarce and hard to get, and calories unavoidable. Houston- or shall I say San Antonio…we have a problem! A great, big deluge of a problem…
-and that means building a whole levee
-when, and only when, we have a counterforce commensurate with the whole flood will the waters recede, the tide turn, the ground dry out, and new WAYS open up before us, that might allow what has to date been the road less traveled- the road to health- become a path of far lesser resistance…
-the Yale-Griffin Prevention Research Center, and my non-profit, Turn the Tide, are assembly lines, devoted to producing sandbags…
Food is medicine- but can we get the medicine to go down?
-we say knowledge is power, but it isn’t true…
-we say where there’s a will, there’s a way- but that isn’t true either! The lack of way may undo steadfast will. The way may conspire mightily against the pursuit of health and promises fulfilled, as, indeed, the modern way does…
--we don’t know if Frost’s sigh was of contentment, or regret- but we do get the impression his choice was irrevocable…
So it is that I conclude
This half-baked talk on health and food
And do so hoping to have taught
Or served, at least
Some food for thought!
-fin