Nahatame, S. (2016, August). Text coherence perceived by Japanese learners of English: The role of sentence connectivity and language proficiency. Poster presented at the Annual Conference of the Euro Second Language Association, Jyväskylä, Finland.
Dynamic assessment and academic writing: evidence of learning transfer?Prithvi Shrestha
In the context of higher education, many higher order skills and knowledge are expected to be transferable by lecturers. Sustaining these skills and knowledge is therefore central to learning and disciplinary writing development. English for Specific Purposes (ESP) courses can contribute to this purpose as they aim to enable Higher Education students to participate in their chosen academic communities as fully as possible. Despite learning transfer being a key purpose in ESP, research in this area is still limited (Cheng, 2007).
In this context, this paper reports on a small-scale study investigating the transfer of academic writing skills and conceptual knowledge among undergraduate business studies students. The data are derived from a larger study (Shrestha, 2011) conducted at a British university. One assignment text each was collected from four students who studied an ESP course for business studies. While three students had received interactive feedback on their previous two assignments, following a Vygotsky-inspired dynamic assessment (DA) approach, one student was provided with traditional tutor feedback. DA blends instruction with assessment by targeting and further developing students’ potential abilities (Poehner, 2011) whereas traditional tutor feedback is less interactive and hence, may not sufficiently target learners’ potential abilities. The student texts were analysed by drawing on Vygotskian sociocultural theory of learning (Vygotsky, 1978), and genre theory (Martin & Rose, 2007) based on Halliday’s Systemic Functional Linguistics (Halliday & Matthiessen, 2004). The findings suggest that the transfer of academic writing skills and conceptual knowledge occurred more in the texts of the students that underwent dynamic assessment than that of the student who followed a traditional assessment approach for their first two assignments. Implications of this for ESP instruction and assessment design will be presented.
Investigating Teachers' Perceptions of FluencyEllen Head
Summary of research into fluency in foreign language, with results of a small-scale replication study to find out what teachers think is important when assessing fluency. Sound files can be found on Soundcloud User 928438004 uploads of sample 1, 2 and 3.
there is the study of contributions which these two descipline could have about each other in implementation of rules & theories and in the relm of research they can help each other
The Role of Writing and Reading Self Efficacy in First-year Preservice EFL Te...Seray Tanyer
A conference paper presented at GlobELT 2015: An International Conference on Teaching and Learning English as an Additional Language (16 – 19 April 2015)
Dynamic assessment and academic writing: evidence of learning transfer?Prithvi Shrestha
In the context of higher education, many higher order skills and knowledge are expected to be transferable by lecturers. Sustaining these skills and knowledge is therefore central to learning and disciplinary writing development. English for Specific Purposes (ESP) courses can contribute to this purpose as they aim to enable Higher Education students to participate in their chosen academic communities as fully as possible. Despite learning transfer being a key purpose in ESP, research in this area is still limited (Cheng, 2007).
In this context, this paper reports on a small-scale study investigating the transfer of academic writing skills and conceptual knowledge among undergraduate business studies students. The data are derived from a larger study (Shrestha, 2011) conducted at a British university. One assignment text each was collected from four students who studied an ESP course for business studies. While three students had received interactive feedback on their previous two assignments, following a Vygotsky-inspired dynamic assessment (DA) approach, one student was provided with traditional tutor feedback. DA blends instruction with assessment by targeting and further developing students’ potential abilities (Poehner, 2011) whereas traditional tutor feedback is less interactive and hence, may not sufficiently target learners’ potential abilities. The student texts were analysed by drawing on Vygotskian sociocultural theory of learning (Vygotsky, 1978), and genre theory (Martin & Rose, 2007) based on Halliday’s Systemic Functional Linguistics (Halliday & Matthiessen, 2004). The findings suggest that the transfer of academic writing skills and conceptual knowledge occurred more in the texts of the students that underwent dynamic assessment than that of the student who followed a traditional assessment approach for their first two assignments. Implications of this for ESP instruction and assessment design will be presented.
Investigating Teachers' Perceptions of FluencyEllen Head
Summary of research into fluency in foreign language, with results of a small-scale replication study to find out what teachers think is important when assessing fluency. Sound files can be found on Soundcloud User 928438004 uploads of sample 1, 2 and 3.
there is the study of contributions which these two descipline could have about each other in implementation of rules & theories and in the relm of research they can help each other
The Role of Writing and Reading Self Efficacy in First-year Preservice EFL Te...Seray Tanyer
A conference paper presented at GlobELT 2015: An International Conference on Teaching and Learning English as an Additional Language (16 – 19 April 2015)
The impact of structure on word meaning and fill in-the-blank tests procedure...Dr. Seyed Hossein Fazeli
The purpose of research described in the current study to investigate the impact of structure knowing on two types of test, i.e. word-meaning test and fill-in-the-blank test, their correlation and procedures on both short-term and long-term retention of vocabulary items. The importance of the present study, to test the condition that learners are not allowed to use guess strategy or randomly answer the tests and they should give reason semantically for their answer, otherwise their answer, even is correct, is not scored. The population for subject recruitment was all undergraduate students from second semester at large university in Iran (both male and female) that study English as a compulsory paper. In Iran, English is taught as a foreign language.
The Lexical Profile of Diverse and Sophisticated Academic EssaysMelanie Gonzalez
Presentation at the 14th Annual Symposium on Second Language Research in Auckland, New Zealand
Abstract: This presentation reports on a study that examined the contribution of word frequency to lexical diversity and sophistication in academic writing proficiency. Findings suggest that mid-frequency vocabulary may have a greater role than is typically given in the L2 composition classroom. Implications for practice and further analysis are discussed.
Using Probability Analysis in Investigating Denotative Values on Teachers’ Pe...iosrjce
This article examines responses obtained from teachers’ questionnaires to test and answer this
research question “What are Moroccan EFL high school teachers’ perceptions of the teaching/learning process
of speaking skills?” Two quantitative frequencies investigating both the rate of teaching speaking and the
position it holds among the other skills shall be used. On the one hand, tables used include a summary to the
Chi square results obtained on teachers’ perceptions of the frequency of teaching speaking in Moroccan
secondary school EFL classes. On the other hand, the second part is an attempt to determine the position of
speaking in comparison to the other skills. More results pertaining to teachers’ perceptions will be highlighted
with the content analysis of the interviews done with teachers.
Integrating Incoming Information into Discourse Model in Tunisian ArabicDr. Marwa Mekni-Toujani
There are two main lines in discourse processing research. The first one is interested in understanding the type of inferences that constitute discourse representations (logical inferences, bridging inferences, elaborative inferences, predictive inferences, etc.) (Stewart, Kidd, & Haigh, 2009). The second line is interested in the time course of integrating incoming information with the unfolding discourse model (ibid). This study addressed the second line of research. Incoming information can be integrated as soon as it is available (early integration model) or it is integrated later as a wrap-up operation (delayed integration model) (Guzman & Klin, 2000). That is, the endeavor of the present study was to gauge the time course of connecting incoming information to information mentioned earlier in the text that are no longer available in Working Memory (WM). Additionally, There are some factors that are believed to affect the time course of the generation of discourse-level representations. In fact, Hannon & Daneman (2001) argue that cognitive styles can influence the ability to detect anomalies. Concerning task demands, it is argued that some instructions require different strategies by the reader (Smith & O’Brien, 2012). Hence, this study explored the effects of both field-dependency and task demands. Ultimately, the present study aspired to answer the following research questions: (1) does readers’ sensitivity to spatial anomaly affect the time-course of integrating incoming information into the unfolding discourse model in Tunisian Arabic (TA)? (2) do field dependency and task demands affect the time-course of integration in TA?
The Effect of Grammar vs. Vocabulary Pre-teaching on EFL Learners’ Reading Comprehension: A Schema-Theoretic View of Reading - Dr. Ali Jahangard Assistant professor of Sharif University of Technology
Dr. Ahmad Moinzadeh Assistant professor of University of Isfahan
Akbar Karimi, M.A Student of Mobarakeh Board of Education, Isfahan Abstract
**** summary by www.sepatubordir.com
Regarding the importance of the term corrective feedback, this study was an attempt to investigate probable impacts of explicit and implicit corrective feedbacks on learners’ levels of grammatical range and accuracy in their language learning and production. One-hundred pre-intermediate EFL learners, with an age range of 18-26, were participated in this study. They were assigned into four groups: one control group who received no treatment and three experimental groups who received three different types of corrective feedbacks (recast, error code, and explanation). The outcomes of the present study confirmed the efficacy of explicit feedback strategies than that of implicit and suggested that learners who used explanation as an explicit corrective feedback strategy achieved higher scores than those who used recast and error code feedback strategies.
Administering the DRA 2: Diagnostic Reading AssessmentFaymus Copperpot
This is a teacher's workshop to show how to use the DRA 2: Diagnostic Reading Assessment. Teacher will have the opportunity to learn how to use the program during this workshop.
Second Language Acquisition related to testing model in Finland, and its implications for designing future technology for innovative testing generations to come.
Does Pronunciation Instruction Promote Intelligibility and Comprehensibility?ozpar
This Powerpoint describes a study conducted with ESL speakers enrolled in a U.S. university to determine the impact of teaching segmentals and suprasegmentals on intelligibility and comprehensibility.
The impact of structure on word meaning and fill in-the-blank tests procedure...Dr. Seyed Hossein Fazeli
The purpose of research described in the current study to investigate the impact of structure knowing on two types of test, i.e. word-meaning test and fill-in-the-blank test, their correlation and procedures on both short-term and long-term retention of vocabulary items. The importance of the present study, to test the condition that learners are not allowed to use guess strategy or randomly answer the tests and they should give reason semantically for their answer, otherwise their answer, even is correct, is not scored. The population for subject recruitment was all undergraduate students from second semester at large university in Iran (both male and female) that study English as a compulsory paper. In Iran, English is taught as a foreign language.
The Lexical Profile of Diverse and Sophisticated Academic EssaysMelanie Gonzalez
Presentation at the 14th Annual Symposium on Second Language Research in Auckland, New Zealand
Abstract: This presentation reports on a study that examined the contribution of word frequency to lexical diversity and sophistication in academic writing proficiency. Findings suggest that mid-frequency vocabulary may have a greater role than is typically given in the L2 composition classroom. Implications for practice and further analysis are discussed.
Using Probability Analysis in Investigating Denotative Values on Teachers’ Pe...iosrjce
This article examines responses obtained from teachers’ questionnaires to test and answer this
research question “What are Moroccan EFL high school teachers’ perceptions of the teaching/learning process
of speaking skills?” Two quantitative frequencies investigating both the rate of teaching speaking and the
position it holds among the other skills shall be used. On the one hand, tables used include a summary to the
Chi square results obtained on teachers’ perceptions of the frequency of teaching speaking in Moroccan
secondary school EFL classes. On the other hand, the second part is an attempt to determine the position of
speaking in comparison to the other skills. More results pertaining to teachers’ perceptions will be highlighted
with the content analysis of the interviews done with teachers.
Integrating Incoming Information into Discourse Model in Tunisian ArabicDr. Marwa Mekni-Toujani
There are two main lines in discourse processing research. The first one is interested in understanding the type of inferences that constitute discourse representations (logical inferences, bridging inferences, elaborative inferences, predictive inferences, etc.) (Stewart, Kidd, & Haigh, 2009). The second line is interested in the time course of integrating incoming information with the unfolding discourse model (ibid). This study addressed the second line of research. Incoming information can be integrated as soon as it is available (early integration model) or it is integrated later as a wrap-up operation (delayed integration model) (Guzman & Klin, 2000). That is, the endeavor of the present study was to gauge the time course of connecting incoming information to information mentioned earlier in the text that are no longer available in Working Memory (WM). Additionally, There are some factors that are believed to affect the time course of the generation of discourse-level representations. In fact, Hannon & Daneman (2001) argue that cognitive styles can influence the ability to detect anomalies. Concerning task demands, it is argued that some instructions require different strategies by the reader (Smith & O’Brien, 2012). Hence, this study explored the effects of both field-dependency and task demands. Ultimately, the present study aspired to answer the following research questions: (1) does readers’ sensitivity to spatial anomaly affect the time-course of integrating incoming information into the unfolding discourse model in Tunisian Arabic (TA)? (2) do field dependency and task demands affect the time-course of integration in TA?
The Effect of Grammar vs. Vocabulary Pre-teaching on EFL Learners’ Reading Comprehension: A Schema-Theoretic View of Reading - Dr. Ali Jahangard Assistant professor of Sharif University of Technology
Dr. Ahmad Moinzadeh Assistant professor of University of Isfahan
Akbar Karimi, M.A Student of Mobarakeh Board of Education, Isfahan Abstract
**** summary by www.sepatubordir.com
Regarding the importance of the term corrective feedback, this study was an attempt to investigate probable impacts of explicit and implicit corrective feedbacks on learners’ levels of grammatical range and accuracy in their language learning and production. One-hundred pre-intermediate EFL learners, with an age range of 18-26, were participated in this study. They were assigned into four groups: one control group who received no treatment and three experimental groups who received three different types of corrective feedbacks (recast, error code, and explanation). The outcomes of the present study confirmed the efficacy of explicit feedback strategies than that of implicit and suggested that learners who used explanation as an explicit corrective feedback strategy achieved higher scores than those who used recast and error code feedback strategies.
Administering the DRA 2: Diagnostic Reading AssessmentFaymus Copperpot
This is a teacher's workshop to show how to use the DRA 2: Diagnostic Reading Assessment. Teacher will have the opportunity to learn how to use the program during this workshop.
Second Language Acquisition related to testing model in Finland, and its implications for designing future technology for innovative testing generations to come.
Does Pronunciation Instruction Promote Intelligibility and Comprehensibility?ozpar
This Powerpoint describes a study conducted with ESL speakers enrolled in a U.S. university to determine the impact of teaching segmentals and suprasegmentals on intelligibility and comprehensibility.
Support for foreign language listeners: Its effectiveness and limitationsCindy Shen
The assessment of listening comprehension in a second language has
received relatively little attention until recently. This study investigated the effective-
ness of providing different types of listening support for learners in a foreign language
environment with a low level of English proficiency. The research was conducted with
140 students taking an English listening course at a college in Taiwan. The participants
took sections of a listening test under four different conditions. Two of the conditions
provided support in the form of either a set of pictures or a written background text.
The third condition was a repetition of the test input, whereas the fourth one was simply
no type of support. After the test, the participants completed a short questionnaire and
some of them were also interviewed. According to the results, repeating the input was
the most effective treatment, followed by having visual and textual support. However,
the limits of the learners’ English competence meant that all of the types of support
could improve their comprehension only to a certain degree. Nevertheless, the provi-
sion of appropriate support may motivate foreign language learners to improve their
listening proficiency by making adequate comprehension more attainable for them.
The relationship between vocabulary size and diversity in L2 writing (Vocab@V...Melanie Gonzalez
Abstract:
Although vocabulary has long been an important criterion for assessing second language (L2) writing proficiency, recent research on academic discourse has positioned word study as a leading method to improve learner writing. As a result, teachers must make decisions on which words warrant instructional time and how to help learners deploy these words effectively in production. While there has been a growing trend in research investigating word lists, comparatively fewer studies have examined how words are actually used to achieve writing quality.
Thus, the present paper reports the findings of a quantitative study that examined the extent to which vocabulary size and lexical diversity contributed to writing scores on 172 native and advanced non-native English speakers’ academic essays. Results revealed that lexical diversity had a significantly greater impact on writing score than vocabulary size in both native and non-native speaker essays. Nevertheless, vocabulary size did initially facilitate writing scores at the lower score levels; however, it was lexical diversity that promoted an essay into the higher score range. Additional findings demonstrated that vocabulary size had only a moderate relationship to lexical diversity.
Outcomes from this study suggest that variation of mid-range vocabulary may play a more important role in writing proficiency than the use of infrequent terms that signal a larger productive lexicon. Furthermore, the results indicate that it is not enough to simply teach vocabulary words in the L2 composition classroom, but to also guide learners in how to employ these words in a varied manner within their writing.
Tooltip-type, Frame-type, and Concordance Glossing in L2 Readingengedukamall
Lee, J. (2014, September). Tooltip-type, frame-type, and concordance glossing in L2 reading. Paper presented at the meeting of KAMALL Annual Conference 2014, Seoul, Korea.
[Abstract]
This study investigated the effects of three different types of electronic textual
glossing, namely tooltip-type, frame-type, and concordance glossing, on
foreign language (FL) vocabulary acquisition. The present study was primarily
driven by Nation’s (2009) introduction to the different types of glossing
available for enhancing FL vocabulary learning in computer-assisted learning
environments, and his suggestion that these glossing types be compared in
terms of their effectiveness. While the first two glossing types both provide
the definitions of glossed words but are different from each other in terms of
their user interface designs. In the case of tooltip-type glossing, a pop-up box
showing the definition of a glossed word temporarily appears when a reader
hovers the mouse cursor over the glossed word, and it disappears when he
or she moves the cursor away from the word. This glossing format is
designed in such a way that it would not obscure any surrounding contexts
around the glossed word. On the other hand, in the frame-type glossing, the
definition appears in the bottom frame of the screen when a reader clicks the
glossed word. In the concordance glossing, the glossing device is equipped
with concordance sentences involving the glossed words, through which a
reader is given three authentic sentences from two authoritative reference
corpora (“British National Corpus” and “Brown”) in the frame-type format. A
total of 83 university students of English as a Foreign Language (EFL)
participated in the study. They completed a computer-based reading task, a
reading comprehension test, meaning recall vocabulary tests at three different
points in time, and a post-reading questionnaire. Our findings showed that
the intermediate EFL learners were affected not by a difference in terms of
glossing formats, but by the type of information provided, with tooltip-type
and frame-type glossing bringing about more positive outcomes in terms of
vocabulary learning. On the other hand, these glossing types were found to make no difference in terms of students’ reading comprehension. The findings
further revealed that the tooltip-type and frame-type groups made greater
gains of target vocabulary, while the three groups all experienced a similar
amount of cognitive load, and that these groups consequently rated their
respective glossing more positively than the concordance group.
Examination of the Prediction of Different Dimensions of Analytic Relations’ ...Mohammad Mosiur Rahman
An in-depth investigation of analytic relations by lexical researchers plays a prominent role in language learning and
teaching. The primary objective of the present study was to investigate the extent to which prediction regarding different
aspects of analytic relations impacts reading comprehension. The current research employed a quantitative approach
using standard multiple regression analysis. The study compared two language proficiency tests, namely an analytic
relations test and an academic reading comprehension test, among a total of 91 participants with a Bachelor of Business
Administration background and a total of 64 students with a Bachelor of Engineering background. The results of the
study showed that for both the Business and Engineering School students, the component-integral analytic relations
facet of vocabulary depth knowledge was not only the most statistically significant contributing predictor of academic
reading comprehension, but it also had the largest effect (i.e., statistically significant) in explaining the outcome
variable: Academic reading comprehension. By providing insights into the research gap, the present study suggests that
the analytic relations dimension of vocabulary knowledge has practical use for English language learners and English
teachers at the tertiary level, and it offers further implications for lexical researchers.
Causal and semantic relatedness effects on L2 text processing and memory: Evi...Shingo Nahatame
Nahatame, S. (2017, March). Causal and semantic relatedness effects on L2 text processing and memory: Evidence from self-paced reading and recall. Paper presented at the Annual Conference of the American Association for Applied Linguistics, Portalnd.
JALT 2014 Noticing and learning lexical bundlesHaidee Thomson
Language is inherently formulaic and lexical bundles make up a generous proportion of it. Lexical bundles are usually acquired through extensive exposure to fluent discourse. However, in an environment where exposure is limited, intervention may be helpful. This presentation was given at JALT2014: Conversations across borders conference
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
The ability to recreate computational results with minimal effort and actionable metrics provides a solid foundation for scientific research and software development. When people can replicate an analysis at the touch of a button using open-source software, open data, and methods to assess and compare proposals, it significantly eases verification of results, engagement with a diverse range of contributors, and progress. However, we have yet to fully achieve this; there are still many sociotechnical frictions.
Inspired by David Donoho's vision, this talk aims to revisit the three crucial pillars of frictionless reproducibility (data sharing, code sharing, and competitive challenges) with the perspective of deep software variability.
Our observation is that multiple layers — hardware, operating systems, third-party libraries, software versions, input data, compile-time options, and parameters — are subject to variability that exacerbates frictions but is also essential for achieving robust, generalizable results and fostering innovation. I will first review the literature, providing evidence of how the complex variability interactions across these layers affect qualitative and quantitative software properties, thereby complicating the reproduction and replication of scientific studies in various fields.
I will then present some software engineering and AI techniques that can support the strategic exploration of variability spaces. These include the use of abstractions and models (e.g., feature models), sampling strategies (e.g., uniform, random), cost-effective measurements (e.g., incremental build of software configurations), and dimensionality reduction methods (e.g., transfer learning, feature selection, software debloating).
I will finally argue that deep variability is both the problem and solution of frictionless reproducibility, calling the software science community to develop new methods and tools to manage variability and foster reproducibility in software systems.
Exposé invité Journées Nationales du GDR GPL 2024
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Text coherence perceived by Japanese learners of English: The role of sentence connectivity and language proficiency.
1. Text Coherence Perceived by Japanese Learners of English:
The Role of Sentence Connectivity and Language Proficiency
Shingo Nahatame
Kyoei University, Japan
Horiba, Y. (1996). The role of elaborations in L2 comprehension: The effect of encoding task on recall. The
Modern Language Journal, 80, 151–164. doi: 10.1111/j.1540-4781.1996.tb01155.x
Landauer, T. K., Foltz, P. W., & Laham, D. (1998). An introduction to Latent Semantic Analysis. Discourse Processes,
25, 259–284. doi: 10.1080/01638539809545028
Nahatame, S. (2014, March). Effects of semantic and causal relatedness on text memory and coherence judgment
by Japanese EFL learners. Poster presented at the Annual Conference of the American Association for
Applied Linguistics, Portland.
Todaro, S., Millis, K., & Dandotkar, S. (2010). The impact of semantic and causal relatedness and reading skill on
standards of coherence. Discourse Processes, 47, 421–446. doi: 0.1080/01638530903253825
Wolfe, M. B. W., Magliano, J. P., & Larsen, B. (2005). Causal and semantic relatedness in discourse understanding
and representation. Discourse Processes, 39, 165–187. doi: 10.1080/0163853X.2005.9651678
References
Introduction.
• Successful text comprehension requires not only word recognition and syntactic
parsing, but also an understanding of connectivity between sentences.
• Studies suggest two important types of sentence connectivity for
comprehension (e.g., Todaro et al., 2010; Wolfe, 2005):
Causal Relatedness (CR) or cause-and-effect relations
Semantic Relatedness (SR) or semantic overlap between propositions
e.g., Mary could not find anything to read in the library. She went to the bookstore
to get new books. (This text is high in CR and SR.)
• L1 readers perceive both CR and SR between sentences; however, skilled
readers emphasize CR more in their perception, whereas less skilled readers
emphasize SR more in their perception (Todaro, et al., 2010). 1
• Previous studies found L2 learners perceive CR between sentences (Horiba,
1996); however, few studies have explored whether and how they perceive SR.
Research Questions (RQs).
RQ1: How do CR and SR between sentences influence L2 learners’ perception of
text coherence?
RQ2: How do the effects of CR and SR differ according to learners’ L2 proficiency?
• The present study is an approximate replication of the author’s previous study
(Nahatame, 2014).
Introduction
• The main effects of CR and SR were found, with higher ratings for sentences
high in relatedness than those low in relatedness (see Table 3 in Appendix)
• A significant interaction between CR and SR was found, indicating that CR
effects were more prominent for SR-low than SR-high, F(1, 53) = 181.49, p < .001,
ηG
2 = .61; F(1, 47) = 34.07, p < .001, ηG
2 = .25, whereas SR effects were more
prominent for CR-low than CR-high, F(1, 100) = 168.38, p < .001, ηG
2 = .63; F(1, 100) =
92.14, p < .001, ηG
2 = .48
CR and SR had both independent and interacting influences on judgments.
• A significant interaction between CR and L2 proficiency was found, indicating
that CR more greatly affected judgments made by the higher than the lower
proficiency groups, F(1, 55) = 191.56, p < .001, ηG
2 = .67; F(1, 45) = 36.44, p < .001, ηG
2
= .45.
• A significant interaction between SR and L2 proficiency was found, indicating
that SR more greatly affected judgments made by the lower than the higher
proficiency groups , F(1, 45) = 95.16, p < .001, ηG
2 = .51; F(1, 55) = 72.38, p < .001, ηG
2
= .36.
CR had a greater impact on judgments made by proficient learners,
whereas SR had a greater impact on judgments made by less proficient
learners.
Methods
• Participants were classified into either a higher or lower proficiency group
according to scores of the EFL reading test widely used in Japan (EIKEN).
• A mixed three-way ANOVA was conducted on coherence ratings, with SR as a
within-participants variable, and CR and proficiency as between-participants
variables. Effect sizes are discussed along with statistical significance claims.
Analysis • Japanese EFL learners’ perception of text coherence varies according to not only
CR but also SR between sentences.
• All learners do not similarly perceive coherence of the same texts; there exist
individual differences in the perception of text coherence
CR is more important for proficient learners’ coherence perception, and SR is
more important for coherence perception in less proficient learners.
Conclusions
Participants.
• 104 Japanese university EFL students (A1 to B2 levels in CEFR)
Materials.
• 20 experimental passages of two-sentence texts varying in CR and SR (adapted
from Wolfe et al., 2005; see Table 1).
Four types of CR–SR combinations in the first sentence to complement the
second sentence
• CR was verified by subjective ratings in the preliminary study. 2
• SR was calculated by a corpus-based technique called Latent Semantic Analysis
(Landauer et al., 1998). 3
Design and Procedure.
• CR was manipulated between participants, whereas SR was manipulated within
each participant (cf. Nahatame, 2014). 4
z
• Participants were told to read the texts for comprehension and then judged the
coherence of the texts on a 5-point scale. (1 = not coherent at all; 5 = very coherent)
Results & Discussion
Table 1. Example of an Experimental Passage
Figure 1. Boxplots of coherence rating data.
Table 2. Means, 95% CIs, and SDs for the Coherence Judgment Task
SR-High SR-Low
Higher (n = 57) M 95% CI SD M 95% CI SD
CR-High (n = 29) 4.53 [4.32, 4.74] 0.54 4.11 [3.83, 4.39] 0.74
CR-Low (n = 28) 3.28 [3.00, 3.56] 0.72 1.79 [1.58, 2.01] 0.55
Lower (n = 47)
CR-High (n = 20) 4.62 [4.41, 4.83] 0.45 3.38 [2.90, 3.86] 1.04
CR-Low (n = 27) 3.55 [3.29, 3.81] 0.66 1.93 [1.70, 2.17] 0.60
Total
CR-High (n = 49) 4.56 [4.42, 4.71] 0.50 3.81 [3.54, 4.08] 0.94
CR-Low (n = 55) 3.41 [3.22, 3.60] 0.70 1.86 [1.71, 2.02] 0.58
1. Mary could not find anything to read in the library. (CR-High / SR-High)
2. Mary wanted to look for recipes for her dinner party. (CR-High / SR-Low)
3. Mary went to the library to look for something to read. (CR-Low / SR-High)
4. Mary was having a dinner party for her office. (CR-Low / SR-Low)
Target sentence: She went to the bookstore to get new books.
Shingo Nahatame,Kyoei University, Japan
Email: nahatame@kyoei.ac.jp
Website: https://sites.google.com/site/snahatame
Twitter ID: @Nahacchi
Contact
This research was supported by Grants-in-Aid for Research Activity Start-up (15H06571)
from the Japan Society for the Promotion of Science.
Acknowledgement