The Texas Department of Public Safety receives approximately 6,800 drug content toxicology analysis requests per year. Between July 2012 and May 2015, 12,788 positive blood drug content reports were released, with 98.6% from intoxication offenses. Alprazolam was the most frequently reported drug in positive cases, at 41% of all positives. The presentation also showed regional differences in types of drugs detected and concentrations.