Teen acne is caused by a combination of factors including hormones, genetics, and certain medications. During puberty, androgen hormones increase and make the skin's oil glands larger and produce more sebum, potentially leading to acne. If a person's parents had acne, they may be genetically predisposed. Certain medications like epilepsy medication or prednisone can also cause acne breakouts. Cosmetics that are oil-based may clog pores and worsen acne compared to water-based products.