Syncephalastrum is a filamentous fungus commonly found in soil and animal feces in tropical and subtropical regions. It requires two mating strains to produce zygospores through sexual reproduction. Syncephalastrum racemosum is the only species in the genus. It has a branched, coenocytic thallus and reproduces asexually through the production of merosporangiospores on finger-shaped sporangia that form on swollen vesicles at the ends of sporangiophores. Sexual reproduction occurs through the fusion of gametangia to form spherical zygospores.
Introduction,In some fungi ,true sexual cycle comprising of nuclear fusion and meiosis is absent.
These fungi derive the benefits of sexuality through a cycle know as parasexuaL cycle.
First Reported by- Gudio Pontecorvo and J.A.Roper(1952)
Parasexual cycle was reported in
Aspergillus nidulans,the imperfect stage of Emericella nidulans.
Since then parasexual cycle has been discovered not only in several members of Deutromycetes but also in fungi belonging to Ascomycetes and Basidiomycetes.
DEFINETION - Parasexuality is defined as a cycle in which Plasmogamy, Karyogamy and Meiosis [Haploidization] take place in sequence but not at a specified time or at specified points in the life cycle of an organism.
Generally parasexual cycle occurs in those fungi in which true sexual cycle does not take place.
Parasexualcycle also know as Somatic recombination. PASEXUALITY ALSO REPORTED IN SOME ORGANISMS- Aspergillus nigar, Penicillium crysogenum, STEPS OF PARASEXUAL CYCLE - 1) ESTABLISHMENT OF HETEROKARYOSIS, 2) Formation of Heterozygous DIPLOIDS, 3) occasional mitotic crossing-over during multiplication of diploid nuclei, 4)occasional haplodization through aneuploidy , COMPARISION BETWEEN SEXUAL AND PARASEXUAL CYCLE, IMPORTANCE OF PARASEXUALITY, C0NCLUSION
Introduction,In some fungi ,true sexual cycle comprising of nuclear fusion and meiosis is absent.
These fungi derive the benefits of sexuality through a cycle know as parasexuaL cycle.
First Reported by- Gudio Pontecorvo and J.A.Roper(1952)
Parasexual cycle was reported in
Aspergillus nidulans,the imperfect stage of Emericella nidulans.
Since then parasexual cycle has been discovered not only in several members of Deutromycetes but also in fungi belonging to Ascomycetes and Basidiomycetes.
DEFINETION - Parasexuality is defined as a cycle in which Plasmogamy, Karyogamy and Meiosis [Haploidization] take place in sequence but not at a specified time or at specified points in the life cycle of an organism.
Generally parasexual cycle occurs in those fungi in which true sexual cycle does not take place.
Parasexualcycle also know as Somatic recombination. PASEXUALITY ALSO REPORTED IN SOME ORGANISMS- Aspergillus nigar, Penicillium crysogenum, STEPS OF PARASEXUAL CYCLE - 1) ESTABLISHMENT OF HETEROKARYOSIS, 2) Formation of Heterozygous DIPLOIDS, 3) occasional mitotic crossing-over during multiplication of diploid nuclei, 4)occasional haplodization through aneuploidy , COMPARISION BETWEEN SEXUAL AND PARASEXUAL CYCLE, IMPORTANCE OF PARASEXUALITY, C0NCLUSION
Structure and composition of plant virusesDivya Singh
Virus is chemically a nucleoprotein that multiplies only in the living cells and has ability to cause disease.
Nucleic acid may be RNA or DNA that is surrounded by a protective protein coat called capsid.
Plant viruses may be elongated, spherical and bacilliform in shape.
The nucleic acids RNA and DNA may be single stranded or double stranded.
Nucleic acid % is lower in elongated viruses where as spherical viruses contain higher % of nucleic acid.
Disease cycle of wheat loose smut (PAT 201 Fundamentals of plant pathology)KrishnamoorthiM2
Loose smut has a wide distribution and can occur anywhere wheat is produced. It is caused by the fungus Ustilago tritici. Mild symptoms may be present prior to heading, including yellowish leaf streaks and stiff, dark green leaves. Affected plants head out early, producing sterile heads with clumped, sooty olive-black spores in place of healthy glumes and kernels. Spores are not enclosed by the seed coat, so are quickly dispersed by rain or wind after emergence. After spores disperse, only a bare rachis remains with a few fragments of glumes or awns. These spores infect other wheat plants at flowering, causing seed infection. Infected seed appear healthy. The best time to scout is after heading.
There is a tremendous variety of morphologically different conidia produced. The study of development of conidia based on its origin is referred to as “Conidial Ontogeny”.
Mycorrhiza-definition, Types, VAM, Symbiotic development mechanism between AM fungi and host root, pre-, early- and mature- symbiotic phases, Myc factors, Appresorium and arbuscule development, nutrient exchange
Undergraduate students' slide presentation of Plant pathogenesis caused by fungi for SHEQ3329 Agricultural Microbiology under Dr. Khanom Simarani (2014/2015).
This file gives general information about characteristics and importance of the fungi belonging to the order Perenosporalees and its major families albuginaceae, perenosporaceae and pythiaceae
Structure and composition of plant virusesDivya Singh
Virus is chemically a nucleoprotein that multiplies only in the living cells and has ability to cause disease.
Nucleic acid may be RNA or DNA that is surrounded by a protective protein coat called capsid.
Plant viruses may be elongated, spherical and bacilliform in shape.
The nucleic acids RNA and DNA may be single stranded or double stranded.
Nucleic acid % is lower in elongated viruses where as spherical viruses contain higher % of nucleic acid.
Disease cycle of wheat loose smut (PAT 201 Fundamentals of plant pathology)KrishnamoorthiM2
Loose smut has a wide distribution and can occur anywhere wheat is produced. It is caused by the fungus Ustilago tritici. Mild symptoms may be present prior to heading, including yellowish leaf streaks and stiff, dark green leaves. Affected plants head out early, producing sterile heads with clumped, sooty olive-black spores in place of healthy glumes and kernels. Spores are not enclosed by the seed coat, so are quickly dispersed by rain or wind after emergence. After spores disperse, only a bare rachis remains with a few fragments of glumes or awns. These spores infect other wheat plants at flowering, causing seed infection. Infected seed appear healthy. The best time to scout is after heading.
There is a tremendous variety of morphologically different conidia produced. The study of development of conidia based on its origin is referred to as “Conidial Ontogeny”.
Mycorrhiza-definition, Types, VAM, Symbiotic development mechanism between AM fungi and host root, pre-, early- and mature- symbiotic phases, Myc factors, Appresorium and arbuscule development, nutrient exchange
Undergraduate students' slide presentation of Plant pathogenesis caused by fungi for SHEQ3329 Agricultural Microbiology under Dr. Khanom Simarani (2014/2015).
This file gives general information about characteristics and importance of the fungi belonging to the order Perenosporalees and its major families albuginaceae, perenosporaceae and pythiaceae
Deuteromycotina is a polyphyletic group of fungi that reproduce asexually by the generation of conidia (asexual spores). Because these fungi lack a sexual reproductive cycle, they do not have a known sexual stage in their life cycle. The categorization of Deuteromycotina has been debated, as the lack of a documented sexual stage has made determining their evolutionary links with other fungal taxa problematic. With the introduction of molecular biology tools in recent years, several Deuteromycotina species have been reassigned into other fungal phyla based on genetic similarities. Aspergillus, Penicillium, and Trichoderma are examples of Deuteromycotina that are commonly used in the biotechnology and pharmaceutical industries for the synthesis of antibiotics and other chemicals. However, genetic analysis has led to the reclassification of many of these fungi into different phyla.
This pdf is about the Schizophrenia.
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THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
1. Muhammed haneef k a
Asst. Professor
Dept. of botany
Govt. brennen college, thalassery
2. For M.Sc Botany, Kannur University
Order: Mucorales
Family: Syncephalastraceae
Genus: Syncephalastrum
3. For M.Sc Botany, Kannur University
Syncephalastrum is a filamentous fungus that is commonly
isolated from soil and animal feces particularly in tropical and
subtropical areas.
It is a heterothallic fungus and requires a mating strain to
produce zygospores.
Syncephalastrum is commonly considered as a contaminant.
It is very rarely associated with human disease.
Cutaneous infections and onychomycosis
The genus Syncephalastrum contains a single
species; Syncephalastrum racemosum.
4. For M.Sc Botany, Kannur University
Thallus
Branched
Adventitious Rhizoids present
Aseptate
Coenocytic
Colonies are very fast growing, cottony to fluffy, white
to light grey.
Become dark grey with the development of sporangia.
Appear like Aspergillus
5. For M.Sc Botany, Kannur University
Asexual reproduction
Syncephalastrum produces an abundant aerial
mycelium - Sporangiophores.
Sporangiophores terminate in swollen vesicles
Merosporangia (finger-shaped, tubular sporangia)
develop from swollen vesicle.
Each merosporangium contains a single row of 3-18
merosporangiospores.
Merosporangiospores are one celled and spherical to
cylindrical in shape
