This document discusses biohackers and biohacking. It defines a biohacker as someone who engages in biotechnology outside of traditional lab settings, such as in community labs or at home. It provides examples of community biolabs and do-it-yourself biology organizations where biohacking can take place. It also gives examples of projects biohackers work on, from citizen science kits to engineering cells, and notes that the field is growing with more collaboration platforms and community labs.
Webinar titled Hear Me Out: Making Meaningful Connections through Storytelling, part of The Science Network Workshop Series, put together by the Union of Concerned Scientists. The second half of the workshop was offered by Michele Roberts, from the Environmental Justice Health Alliance for Chemical Policy Reform.
An immersive workshop at General Assembly, SF. I typically teach this workshop at General Assembly, San Francisco. To see a list of my upcoming classes, visit https://generalassemb.ly/instructors/seth-familian/4813
I also teach this workshop as a private lunch-and-learn or half-day immersive session for corporate clients. To learn more about pricing and availability, please contact me at http://familian1.com
3 Things Every Sales Team Needs to Be Thinking About in 2017Drift
Thinking about your sales team's goals for 2017? Drift's VP of Sales shares 3 things you can do to improve conversion rates and drive more revenue.
Read the full story on the Drift blog here: http://blog.drift.com/sales-team-tips
Artificial intelligence (AI) is everywhere, promising self-driving cars, medical breakthroughs, and new ways of working. But how do you separate hype from reality? How can your company apply AI to solve real business problems?
Here’s what AI learnings your business should keep in mind for 2017.
Webinar titled Hear Me Out: Making Meaningful Connections through Storytelling, part of The Science Network Workshop Series, put together by the Union of Concerned Scientists. The second half of the workshop was offered by Michele Roberts, from the Environmental Justice Health Alliance for Chemical Policy Reform.
An immersive workshop at General Assembly, SF. I typically teach this workshop at General Assembly, San Francisco. To see a list of my upcoming classes, visit https://generalassemb.ly/instructors/seth-familian/4813
I also teach this workshop as a private lunch-and-learn or half-day immersive session for corporate clients. To learn more about pricing and availability, please contact me at http://familian1.com
3 Things Every Sales Team Needs to Be Thinking About in 2017Drift
Thinking about your sales team's goals for 2017? Drift's VP of Sales shares 3 things you can do to improve conversion rates and drive more revenue.
Read the full story on the Drift blog here: http://blog.drift.com/sales-team-tips
Artificial intelligence (AI) is everywhere, promising self-driving cars, medical breakthroughs, and new ways of working. But how do you separate hype from reality? How can your company apply AI to solve real business problems?
Here’s what AI learnings your business should keep in mind for 2017.
UX, ethnography and possibilities: for Libraries, Museums and ArchivesNed Potter
These slides are adapted from a talk I gave at the Welsh Government's Marketing Awards for the LAM sector, in 2017.
It offers a primer on UX - User Experience - and how ethnography and design might be used in the library, archive and museum worlds to better understand our users. All good marketing starts with audience insight.
The presentation covers the following:
1) An introduction to UX
2) Ethnography, with definitions and examples of 7 ethnographic techniques
3) User-centred design and Design Thinking
4) Examples of UX-led changes made at institutions in the UK and Scandinavia
5) Next Steps - if you'd like to try out UX at your own organisation
How to Become a Thought Leader in Your NicheLeslie Samuel
Are bloggers thought leaders? Here are some tips on how you can become one. Provide great value, put awesome content out there on a regular basis, and help others.
Biological weapons based on genes like myosin or tubulin that are shared at ...beanangel
Biological weapons based on genes like myosin or tubulin that are shared at a wide variety of species are panspecies biocides
Along with the production of the myosin precluding peptides proteins genes or chemicals producing opiate peptides at muscle precluding bioweapons causes sensationless death
Myosin has highly similar gene sequence between numerous species biological weapons that function with siRNA cDNA Gene therapy or intercalating molecules that preclude myosin are deadly at humans to bacteria
Tubulin as well as actin as well as centrioles are things with genetics that could have homologous similarities between a variety of organisms Yeast to humans produce tubulins also actins
It is possible that the codon sequences of FtsZ are sufficiently similar to tubulin to produce a bioweapon that effects numerous prokaryotes as well producing a gene therapy weapon that kills bacteria to yeast to humans
Centrioles are at eukaryotes modifying the genetics of centrioles at a bioweapon precludes cytodivision which also precludes reproduction
"Wie und warum Videolearning funktioniert. Ein Blick in die Wissenschaft" von...Pink University GmbH
„Video is the new text“ – der vielzitierte Ausspruch des Corporate-Learning-Vordenkers Josh Bersin bringt die Bedeutung des Formats Video perfekt auf den Punkt. Auch innerhalb der Weiterbildung sind Schulungsfilme stark auf dem Vormarsch, da sie besser als jedes andere Learning-Tool komplexe Zusammenhänge ebenso verständlich wie unterhaltsam und emotional vermitteln können.
Aber welche wichtigen Erkenntnisse und Praxis-Tipps gibt uns die aktuelle Forschung zum Thema Lernen mit Videos? Darum geht es in diesem wissenschaftlich fundierten und gleichzeitig anwendungsorientierten Vortrag von Wolfgang Hanfstein, der einige der neuesten Erkenntnisse zu dem Thema referiert.
Der Vortrag wurde gehalten am 17.9.2015 auf der HR-Fachmesse Zukunft Personal in Köln.
Die Vita des Referenten Wolfgang Hanfstein, Leiter Corporate Digital Learning des führenden Videolearning-Anbieters Pink University, in Kurzform:
- Diplom-Sozialwissenschaftler
- Langjähriger Lehrbeauftragter im Fachbereich Weiterbildung der Universität Bremen
- Experte für Video-Didaktik
Veröffentlichungen zum Thema Videolearning:
http://www.pinkuniversity.de/e-learning-anbieter/fachbeitraege/
2013 Animal Behavior Society Workshop on Science and Social Media
Sponsored by The Diversity Committee and Latin American Affairs Committee of the Animal Behavior Society
UX, ethnography and possibilities: for Libraries, Museums and ArchivesNed Potter
These slides are adapted from a talk I gave at the Welsh Government's Marketing Awards for the LAM sector, in 2017.
It offers a primer on UX - User Experience - and how ethnography and design might be used in the library, archive and museum worlds to better understand our users. All good marketing starts with audience insight.
The presentation covers the following:
1) An introduction to UX
2) Ethnography, with definitions and examples of 7 ethnographic techniques
3) User-centred design and Design Thinking
4) Examples of UX-led changes made at institutions in the UK and Scandinavia
5) Next Steps - if you'd like to try out UX at your own organisation
How to Become a Thought Leader in Your NicheLeslie Samuel
Are bloggers thought leaders? Here are some tips on how you can become one. Provide great value, put awesome content out there on a regular basis, and help others.
Biological weapons based on genes like myosin or tubulin that are shared at ...beanangel
Biological weapons based on genes like myosin or tubulin that are shared at a wide variety of species are panspecies biocides
Along with the production of the myosin precluding peptides proteins genes or chemicals producing opiate peptides at muscle precluding bioweapons causes sensationless death
Myosin has highly similar gene sequence between numerous species biological weapons that function with siRNA cDNA Gene therapy or intercalating molecules that preclude myosin are deadly at humans to bacteria
Tubulin as well as actin as well as centrioles are things with genetics that could have homologous similarities between a variety of organisms Yeast to humans produce tubulins also actins
It is possible that the codon sequences of FtsZ are sufficiently similar to tubulin to produce a bioweapon that effects numerous prokaryotes as well producing a gene therapy weapon that kills bacteria to yeast to humans
Centrioles are at eukaryotes modifying the genetics of centrioles at a bioweapon precludes cytodivision which also precludes reproduction
"Wie und warum Videolearning funktioniert. Ein Blick in die Wissenschaft" von...Pink University GmbH
„Video is the new text“ – der vielzitierte Ausspruch des Corporate-Learning-Vordenkers Josh Bersin bringt die Bedeutung des Formats Video perfekt auf den Punkt. Auch innerhalb der Weiterbildung sind Schulungsfilme stark auf dem Vormarsch, da sie besser als jedes andere Learning-Tool komplexe Zusammenhänge ebenso verständlich wie unterhaltsam und emotional vermitteln können.
Aber welche wichtigen Erkenntnisse und Praxis-Tipps gibt uns die aktuelle Forschung zum Thema Lernen mit Videos? Darum geht es in diesem wissenschaftlich fundierten und gleichzeitig anwendungsorientierten Vortrag von Wolfgang Hanfstein, der einige der neuesten Erkenntnisse zu dem Thema referiert.
Der Vortrag wurde gehalten am 17.9.2015 auf der HR-Fachmesse Zukunft Personal in Köln.
Die Vita des Referenten Wolfgang Hanfstein, Leiter Corporate Digital Learning des führenden Videolearning-Anbieters Pink University, in Kurzform:
- Diplom-Sozialwissenschaftler
- Langjähriger Lehrbeauftragter im Fachbereich Weiterbildung der Universität Bremen
- Experte für Video-Didaktik
Veröffentlichungen zum Thema Videolearning:
http://www.pinkuniversity.de/e-learning-anbieter/fachbeitraege/
2013 Animal Behavior Society Workshop on Science and Social Media
Sponsored by The Diversity Committee and Latin American Affairs Committee of the Animal Behavior Society
thGAP - BAbyss in Moderno!! Transgenic Human Germline Alternatives ProjectMarc Dusseiller Dusjagr
thGAP - Transgenic Human Germline Alternatives Project, presents an evening of input lectures, discussions and a performative workshop on artistic interventions for future scenarios of human genetic and inheritable modifications.
To begin our lecturers, Marc Dusseiller aka "dusjagr" and Rodrigo Martin Iglesias, will give an overview of their transdisciplinary practices, including the history of hackteria, a global network for sharing knowledge to involve artists in hands-on and Do-It-With-Others (DIWO) working with the lifesciences, and reflections on future scenarios from the 8-bit computer games of the 80ies to current real-world endeavous of genetically modifiying the human species.
We will then follow up with discussions and hands-on experiments on working with embryos, ovums, gametes, genetic materials from code to slime, in a creative and playful workshop setup, where all paticipant can collaborate on artistic interventions into the germline of a post-human future.
What people really want - how #HumanCenteredDesign can help your charity or c...Patrick Olszowski
I was due on stage in 10 minutes and I was totally uncertain if I could do it.
This was me yesterday before I was due to speak at Charity Comms' Psychology of Communications conference.
My entire presentation was a risk. I was going to ask the audience of senior charity sector leaders to do things that I was pretty sure they would find difficult.
I would be rewarding those who worked with me and doing my utmost to persuade others, again and again, who were not yet ready to get involved.
The last time I had presented publicly was in front of an audience of people I knew well. But this was different. Would it work? I had no idea.
Eventually, I went on, starting with a line about how working for yourself is like being a solo polar explorer. Moments of incredible beauty, followed by realising you are surrounded by deep crevasses. I got a laugh and relaxed.
Throughout, people shared their views on the charity sector, by moving up and down an imaginary line in the auditorium - depending on propositions I gave them (and the reactions of other audience members).
I ran another experiment, trialling seven different approaches to get people to sign up to my email newsletter - Top Tips for Tough Problems - all about innovation and charities (www.outrageousimpact.co.uk/tips/)
For those who wouldn't join the email, and were open to it, I had discussions with them on the microphone about what might persuade them. The ability to alter the frequency of emails, sharing this content on LinkedIn and being clearer about what was in the email, persuaded a few.
In the end, 60% of the audience joined the email list and received sweets, a chance to sit in a 'winners' circle', got their name on a plaque on the wall, approval from colleagues, applause and more.
Innovation is about building something new to try and improve lives. It might work. Or flop. But as long as you learn from it, it can never be a failure. That was the key lesson I got yesterday.
This is the presentation you find here.
Patrick
More on: https://www.hackteria.org/wiki/UGM_Organizing_Society_Hackteria_Lecture
This class will discuss how organizing global with an approach of radical transdisciplinarity. As the word radical means root, this organizing is an effort undertaken by citizens to return to its roots as humans or human sapiens. In this organizing practice, staging of the capitalization of knowledge and information becomes a method of producing global knowledge.
There are at least a few elements in the organization that we already know such as:
1) who is involved in it
2) what is the purpose
3) what is it doing
4) how it works
5) how social relations are built
6) how the work agreement is built
7) how the division of labor.
In this class, students are invited to reflect back on the elements in community organizing through practices that have been carried out by Hacteria.org. Thus, students are given the freedom to respond; both reduce, add, redefine the elements of organization that already exist.
Design History and Design Futures: Beyond Anthropocene OntopoliticsEcoLabs
Keynote at Design & Transcience, Design History Society Annual Conference 2022
by Dr. Joanna Boehnert
The significance and risks associated with the Anthropocene diagnosis have yet to be integrated into normative design. This civilisation has yet to ways of living to meet human needs and desires without undermining the climate system and causing the sixth extinction event. For the most part designers are still creating artefacts, products, communications, spaces, processes, services, spaces, and systems that have contributed to the destabilising planetary boundaries and the creation of a new geological epoch: the Anthropocene. And so today I will spend a little time thinking about the kinds of ideas that might help design evolve from propelling the unsustainable and defuturing conditions in the Anthropocene.
Presentation for the NC Tech4Good conference. Discussed: What is data science? How can data science help social good organizations? What is NC Data4Good?
dusjagr & nano talk on open tools for agriculture research and learningMarc Dusseiller Dusjagr
Open Tools for Research, Learning, Sharing in Agriculture and
Society as a whole.
Remote lecture by Marc Dusseiller and Fernando "nano" Castro on open science hardware for agriculture and edication, held for students of microbiology at UGM, Yogyakarta (remote - online )
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
3. What is a “Biohacker”?
(sounds scary)
@krening #sxswbiohackers
4. A Biohacker is an individual who engages
in or tinkers with biotechnology outside of
traditional settings.
(academic, corporate, or government labs)
@krening #sxswbiohackers
5. 1- People w/ science education
2- People without
BiohackerCurious
about
biohacking
@krening #sxswbiohackers