[Presentation by Dr. Vasileios, Gkisakis at the Forum Origin, Diversity and Territories 2019, Lausanne, Switzerland] This contribution analyzes how regional initiatives in Crete, Greece, related to agroecology, support “biocultural diversity” and conservation and significantly contribute to the transition towards sustainable food systems. It utilizes an agroecological and social-ecological conceptual framework that supports deeper understandings of transitions for resilience. Analysis of transdisciplinary literature that addresses constructs of agroecology from the environmental and social sciences will include transitions towards sustainable food systems for biocultural diversity argued through empirical and scientific perspectives. The discussion involves interpretations of scientific terminology (science), implementation strategies (practice) and partnerships for transitions (movements). The examination of the Cretan paradigm include: The “Life IGIC” project (Life+ programme), the “Melitakes” agroecological social cooperative, the Agroecological Network of Greece and the Crete's Culinary Sanctuaries Educational Network. These socio-ecological examples provide insights that include: biodiversity conservation and use, traditional agricultural knowledge, the Mediterranean heritage foodscape, the successes and challenges in transitioning to sustainable foodways, implications of food security and post-carbon resilience. Critical inquiry will include issues of biocapacity along with opportunities and threats from surrounding socio-ecological processes, industries and businesses. Research implications offer advancements for policy-oriented decision making that can prepare communities for resilience in changing climates, economies and post-carbon contexts.