The document defines stress as occurring when pressures exceed one's ability to cope (S=P>R). It notes that 80% of modern diseases have stress as their root cause and that long-term stress can physically affect the brain by shrinking the hippocampus. The document lists personal, organizational, mental, and social factors as common reasons for stress and describes physical, mood, behavioral, and cognitive symptoms. Finally, it provides tips for managing stress such as lifestyle analysis, maintaining balance between demands and supplies, learning to say no, practicing self-help, using time management tools, and recognizing that moderate stress can improve memory and focus.