The document discusses best practices for building and maintaining relationships with thought leaders and key opinion leaders to serve as speakers for pharmaceutical companies. It recommends identifying and quantifying the thought leader base and developing relationships through alignment of strategic objectives, excellent customer service, seamless program execution, regulatory compliance, and consensus on measuring success. Specific recommendations include engaging thought leaders in content development, aligning content with audience needs, timely logistics and compensation, integrating compliance teams, and measuring both strategic and tactical success through cross-functional teams.