The document summarizes a presentation on stem cell research, including:
1) Current status allows non-federal funding but bans federal funding for research destroying embryos.
2) Sources include adult, embryonic, and cloned stem cells.
3) South Korean researcher Hwang Woo Suk falsified data on human cloning.
4) Ethical review committees assess special respect for embryos, scientific merit, and protection of donors.
The Chinese half of my Ricci Scholar project and the basis for a 45 minute lecture. Personally, I think the pictures in it (also by me) are way more interesting than the presentation.
The Chinese half of my Ricci Scholar project and the basis for a 45 minute lecture. Personally, I think the pictures in it (also by me) are way more interesting than the presentation.
Operation âBlue Starâ is the only event in the history of Independent India where the state went into war with its own people. Even after about 40 years it is not clear if it was culmination of states anger over people of the region, a political game of power or start of dictatorial chapter in the democratic setup.
The people of Punjab felt alienated from main stream due to denial of their just demands during a long democratic struggle since independence. As it happen all over the word, it led to militant struggle with great loss of lives of military, police and civilian personnel. Killing of Indira Gandhi and massacre of innocent Sikhs in Delhi and other India cities was also associated with this movement.
Palestine last event orientationfvgnh .pptxRaedMohamed3
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An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdfTechSoup
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In this webinar you will learn how your organization can access TechSoup's wide variety of product discount and donation programs. From hardware to software, we'll give you a tour of the tools available to help your nonprofit with productivity, collaboration, financial management, donor tracking, security, and more.
Embracing GenAI - A Strategic ImperativePeter Windle
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Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Introduction to AI for Nonprofits with Tapp NetworkTechSoup
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Dive into the world of AI! Experts Jon Hill and Tareq Monaur will guide you through AI's role in enhancing nonprofit websites and basic marketing strategies, making it easy to understand and apply.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
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http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasnât one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
Operation âBlue Starâ is the only event in the history of Independent India where the state went into war with its own people. Even after about 40 years it is not clear if it was culmination of states anger over people of the region, a political game of power or start of dictatorial chapter in the democratic setup.
The people of Punjab felt alienated from main stream due to denial of their just demands during a long democratic struggle since independence. As it happen all over the word, it led to militant struggle with great loss of lives of military, police and civilian personnel. Killing of Indira Gandhi and massacre of innocent Sikhs in Delhi and other India cities was also associated with this movement.
Palestine last event orientationfvgnh .pptxRaedMohamed3
Â
An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdfTechSoup
Â
In this webinar you will learn how your organization can access TechSoup's wide variety of product discount and donation programs. From hardware to software, we'll give you a tour of the tools available to help your nonprofit with productivity, collaboration, financial management, donor tracking, security, and more.
Embracing GenAI - A Strategic ImperativePeter Windle
Â
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Introduction to AI for Nonprofits with Tapp NetworkTechSoup
Â
Dive into the world of AI! Experts Jon Hill and Tareq Monaur will guide you through AI's role in enhancing nonprofit websites and basic marketing strategies, making it easy to understand and apply.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
Â
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasnât one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
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Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
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Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
This Congress will not stand idly by and allow an environment hostile to Jewish students to persist. The House believes that your institution is in violation of Title VI of the Civil Rights Act, and the inability or
unwillingness to rectify this violation through action requires accountability.
Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
The House of Representatives will not countenance the use of federal funds to indoctrinate students into hateful, antisemitic, anti-American supporters of terrorism. Investigations into campus antisemitism by the Committee on Education and the Workforce and the Committee on Ways and Means have been expanded into a Congress-wide probe across all relevant jurisdictions to address this national crisis. The undersigned Committees will conduct oversight into the use of federal funds at MIT and its learning environment under authorities granted to each Committee.
âĸ The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
âĸ The Committee on Oversight and Accountability is investigating the sources of funding and other support flowing to groups espousing pro-Hamas propaganda and engaged in antisemitic harassment and intimidation of students. The Committee on Oversight and Accountability is the principal oversight committee of the US House of Representatives and has broad authority to investigate âany matterâ at âany timeâ under House Rule X.
âĸ The Committee on Ways and Means has been investigating several universities since November 15, 2023, when the Committee held a hearing entitled From Ivory Towers to Dark Corners: Investigating the Nexus Between Antisemitism, Tax-Exempt Universities, and Terror Financing. The Committee followed the hearing with letters to those institutions on January 10, 202
The Roman Empire A Historical Colossus.pdfkaushalkr1407
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The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesarâs dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empireâs birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empireâs society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
The French Revolution Class 9 Study Material pdf free download
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Stem_Cell_Research.ppt
1. Stem Cell Research:
Ethical Issues, ESCRO
Committees, and Beyond
Michael Kalichman
Biomedical Ethics Seminar Series
May 17, 2006
2. Status of research
ī¯ Not forbidden in U.S.
ī¯ Forbidden to use federal funds:
īŽ any project in which a human embryo would be
"destroyed, discarded, or knowingly subjected to
risk of injury or deathâ (Dickey. 1996)
ī¯ Federal funds may be used for research on
stem cell lines derived prior to August 9,
2001 (Bush)
ī¯ With non-federal funds this research is still
allowable
4. Hwang Woo Suk
ī¯ Veterinary Researcher,
Seoul National University,
South Korea
ī¯ Stem cell research funded extensively by
Korean government and international
community
ī¯ Collaboration with U.S. scientist:
Gerald Schatten
ī¯ June 2005, Science: Nuclear transfer into 11
human eggs
5. Hwang Woo Suk
What went wrong?
ī¯ Standards of research
ī¯ Falsification of data
ī¯ Fabrication of data
ī¯ And it was stem cell researchâĻ
6. âBeing too focused on scientific development,
I may not have seen all the ethical issues
related to my research.â
Hwang Woo Suk
November 24, 2005
7. "The fraudulent stem-cell research reported by
South Korean scientists suggests that
American institutions are incapable of policing
themselves to prevent similar scandals in this
country, the chairman of a Congressional
subcommittee said on Tuesday."
Jeffrey Brainard, Wednesday, March 8, 2006
âMembers of Congress Spar Over South Korean Cloning Scandal
and Oversight of Stem-Cell Research in U.S.â
Chronicle for Higher Education
March 8, 2006
8. What are we doing?
ī¯ RCR Courses
ī¯ IRB and IACUC Reviews
ī¯ NAS Guidelines
ī¯ CIRM Guidelines
9. What is supposed to be reviewed?
ī¯ Covered stem cell line means a culture-derived,
human stem cell population that is capable of: 1)
sustained propagation in culture; 2) differentiation
along multiple cell lineages; and 3) self-renewing to
produce daughter cells with equivalent developmental
potential. This definition includes both embryonic and
non-embryonic human stem cell lines regardless of
the tissue of origin
ī¯ CIRM Draft Guidelines: 2/10/06
10. What is supposed to be reviewed?
ī¯ Covered stem cell line means a culture-derived,
human pluripotent stem cell population that is capable
of: 1) sustained propagation in culture; and (2) self-
renewal to produce daughter cells with equivalent
developmental potential. This definition includes both
embryonic and non-embryonic human stem cell lines
regardless of the tissue of origin. Pluripotent means
capable of differentiation into mesoderm, ectoderm,
and endoderm."
ī¯ CIRM Draft Guidelines: 5/9/06
11. Why should we review this
research?
ī¯ We already have review committees
ī¯ Is hESC research different?
ī¯ What interests are we protecting with
review of hESC research?
12. Special Respect
"Persons holding the latter view-that the embryo itself
lacks interests or rights because of its extremely
rudimentary development--do not, however, necessarily
view embryos as identical to any other human tissue.
Indeed, many such persons would say that embryos,
though lacking rights or interests in themselves, deserve
"special respect" because of the embryo's potential, if
placed in a uterus, to become a fetus and eventually to
be born. Even embryos that will not be placed in the
uterus have some meaning in this regard for they operate
as a symbol of human life or constitute an arena for
expressing one's commitment to human life.â
(Robertson, 1999)
13. Why should scientists insist on
ethical review of hESC research?
ī¯ Respect for life: developing embryo should
be given closer scrutiny than adult cells
ī¯ Ethical defensibility: strengthened by an
independent ethical review
ī¯ Public accountability:
īŽ watched closely by the public
īŽ especially by those who are morally opposed
īŽ we need a proactive and serious role in
addressing the ethical dimensions of our work
14. Goal for Discussion
ī¯ Framework for review
ī¯ Will not focus on:
īŽ separation of funding sources
īŽ apportioning intellectual property rights
15. Ethical Dimensions of
Stem Cell Research
ī¯ Should we use human embryos?
ī¯ What questions should be studied?
ī¯ How should research be conducted?
ī¯ Who should benefit?
ī¯ Who should bear the costs?
ī¯ Who decides?
16. Ethical factors in hESC research
1. Special Respect
2. Why the study will be conducted
3. What will be studied
4. How the study will be conducted
5. Scientific merit
17. Special Respect
Category Questions
Replacement Can the research goals be met without destroying a human
embryo and with an alternative approach that raises less
severe ethical challenges?
Refinement If the research goals are best met by using human embryos,
is it possible to do so without destroying the embryo or it is
possible to do so by means that will not impair possible
future development of the embryo?
Reduction Can the research goals be met with the use of fewer human
embryos?
Russell and Burch, 1959
18. Ethical factors in hESC research
1. Special Respect
2. Why the study will be conducted
3. What will be studied
4. How the study will be conducted
5. Scientific merit
19. Why the study will be conducted
Category Questions
Basic
research
Is the primary purpose of the study a better understanding of biology or
disease mechanisms?
Prevention Is the primary purpose of the study to develop treatments or devices that
will prevent the occurrence of illness or disease?
Cure Is the primary purpose of the study to develop treatments or devices that
will cure existing illness or disease?
Treatment Is the primary purpose of the study to develop treatments or devices that
will treat, but not necessarily cure, existing illness or disease?
Enhancement Is the primary purpose of the study to develop treatments or devices that
are designed to enhance the human condition?
20. Ethical factors in hESC research
1. Special Respect
2. Why the study will be conducted
3. What will be studied
4. How the study will be conducted
5. Scientific merit
21. What will be studied
Category Questions
Species Will this project involve human tissue? non-human
primates? Mixing of human and non-human species?
Oocytes Who will be the donors? Will the research require that
human oocytes, zygotes, or blastocysts be destroyed,
discarded, or damaged?
Zygotes
Blastocysts
Fetus Who will be the donors? How did the fetal tissue become
available?
Child or Adult Who will be the donors? What tissues will be donated?
22. Ethical factors in hESC research
1. Special Respect
2. Why the study will be conducted
3. What will be studied
4. How the study will be conducted
5. Scientific merit
23. How the study will be conducted
Category Questions
Pain and
suffering
Will the study cause or risk injury of an organism that has sufficient neural
organization to experience physical pain? self-awareness? memory?
Informed and
voluntary
consent
How will informed consent be obtained? What measures will be taken to
ensure that the consent is voluntary, not coerced, and informed?
Surrogate
consent
If the proposed donor lacks the capacity to provide informed and voluntary
consent, will consent be provided by a surrogate who will adequately
consider the interests of the donor?
Alternative uses Are the cells or tissues generated for the purpose of the research project or
were they spontaneously or intentionally generated for some other use?
24. How the study will be conducted
Category Questions
Characterization Will the study consist only of genetic, biochemical, or morphological
characterizations of cells?
Differentiation Will the study consist of genetic or chemical manipulations to induce
differentiation or commitment to more specific lineages?
De-Differentiation Will the study consist of genetic or chemical manipulations to induce
cells to revert to a less differentiated state?
Somatic cell
nuclear transfer
Will nuclear material from diploid cells be inserted into oocytes?
Mixing of species Will genetic material, cells or tissues of a non-human species be inserted
into a human organism? Will genetic material, cells or tissues of human
origin be inserted into a non-human species?
25. Ethical factors in hESC research
1. Special Respect
2. Why the study will be conducted
3. What will be studied
4. How the study will be conducted
5. Scientific merit
26. Scientific merit
Category Questions
Clear
hypothesis or
question
Is the proposed study designed to address a clearly stated hypothesis or
question?
Awareness of
literature
Is the design of the proposed study consistent with what has previously
been published?
Duplication
of previous
work
Does the proposed study duplicate work that has already been done? If so,
then is a rationale provided to adequately justify the need for the
duplication?
Qualifications
of personnel
Are the personnel who will perform the studies adequately trained in
science and methodology? in the ethical, legal, and social implications of
this line of research?