This document summarizes the track record and achievements of Systems Biology Ireland since 2009. It notes that researchers have hosted over 130 international collaborators and funded over 50 postgraduates. Systems Biology Ireland has secured over €47.7 million in funding and their researchers have over 300 publications and invited presentations. Prof. Des Higgins was listed as one of the world's most influential minds in 2015. Prof. Cormac Taylor received the 2015 Nature Award for Mentoring in Science. Systems Biology Ireland was also named the 2014 Irish Education Lab of the Year. The document quotes a representative from AstraZeneca who praises their collaboration with Systems Biology Ireland.