Prescription without diagnosis culpable negligenceArunSharma10
Prescription Without Diagnosis Leads To Culpable Negligence: High Court
Prescription sans diagnosis resulting in patient's death is culpable negligence
Prescription Without Diagnosis Is Culpable Negligence: Bombay HC To Doctor Couple
Don't prescribe medicines without a diagnosis
No prescription on the telephone
Medical negligence case from gynecology
Exercise caution while discharging patients after surgery
Prescription without diagnosis culpable negligenceArunSharma10
Prescription Without Diagnosis Leads To Culpable Negligence: High Court
Prescription sans diagnosis resulting in patient's death is culpable negligence
Prescription Without Diagnosis Is Culpable Negligence: Bombay HC To Doctor Couple
Don't prescribe medicines without a diagnosis
No prescription on the telephone
Medical negligence case from gynecology
Exercise caution while discharging patients after surgery
ISALẸ AGBARA PHC COMMUNITY DIAGNOSIS FIELD WORK FEB 2024.pptxTolu Morakinyo
The fieldwork comprised a thorough community diagnosis conducted by 38 Public Health students from Osun State University, Osogbo, in February 2024, within the Isalẹ Agbara Community Area of Isalẹ Osun, Osogbo, Osun State, Nigeria.
Four methodological approaches were employed:
1. Systematic review of the GOPD Register at the Community's Primary Health Care (PHC) facility to ascertain health-related trends and patterns.
2. Utilization of structured questionnaires administered to community residents to elucidate environmental health concerns and solicit community perspectives.
3. Conducting key informant interviews with PHC personnel to obtain insights into the prevalent health condition in the health facility.
4. Facilitating focus group discussions among community members to know the prevalent health issues in the community
These methodologies/tools enabled a comprehensive assessment of the community health needs and challenges, facilitating evidence-based interventions and policy formulation to enhance public health outcomes and interventions.
An open policy forum on child injury prevention took place in Dublin Castle on the 18th November. The purpose of the policy forum is to support the development of a Child Injury Prevention Action Plan for the Republic of Ireland. Professor Kevin Balanda, from the Institute of Public Health in Ireland (IPH) contributed to the forum by giving a presentation on the day looking at ‘mortality, hospital admissions and self/carer reports of child unintentional injury in the Republic of Ireland from 2006-2015’, the report of which will be published by then end of 2016. The presentation provides contextual information about the occurrence of injuries and so is helpful to support the development of the Action Plan making some recommendations for policy focus and highlighting gaps in the research that need to be addressed.
Homoeopathic Management of Chronic Sinusitisijtsrd
Of all the respiratory tract infections, chronic sinusitis is one of the most common. It interferes with patient’s quality of life and loss of work productivity. It may affect 5 to 13 of the general population. Chronic sinusitis is most frequent disease seen in the clinical practice in middle age group and children. It is the fifth most common disease for which antibiotics are prescribed. Patients undergoing treatment with repeated courses of antibacterial agents and multiple sinus surgeries, have increased risk of colonization with antibiotic resistant pathogens and of surgical complications. Homoeopathic therapy is associated with improvement in a range of chronic and recurring pathologies or allergyand also strengthens immune system, thereby preventing recurrent attacks. Dr. Urmila Bhalgariya "Homoeopathic Management of Chronic Sinusitis" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-2 , February 2022, URL: https://www.ijtsrd.com/papers/ijtsrd49177.pdf Paper URL: https://www.ijtsrd.com/medicine/other/49177/homoeopathic-management-of-chronic-sinusitis/dr-urmila-bhalgariya
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
ISALẸ AGBARA PHC COMMUNITY DIAGNOSIS FIELD WORK FEB 2024.pptxTolu Morakinyo
The fieldwork comprised a thorough community diagnosis conducted by 38 Public Health students from Osun State University, Osogbo, in February 2024, within the Isalẹ Agbara Community Area of Isalẹ Osun, Osogbo, Osun State, Nigeria.
Four methodological approaches were employed:
1. Systematic review of the GOPD Register at the Community's Primary Health Care (PHC) facility to ascertain health-related trends and patterns.
2. Utilization of structured questionnaires administered to community residents to elucidate environmental health concerns and solicit community perspectives.
3. Conducting key informant interviews with PHC personnel to obtain insights into the prevalent health condition in the health facility.
4. Facilitating focus group discussions among community members to know the prevalent health issues in the community
These methodologies/tools enabled a comprehensive assessment of the community health needs and challenges, facilitating evidence-based interventions and policy formulation to enhance public health outcomes and interventions.
An open policy forum on child injury prevention took place in Dublin Castle on the 18th November. The purpose of the policy forum is to support the development of a Child Injury Prevention Action Plan for the Republic of Ireland. Professor Kevin Balanda, from the Institute of Public Health in Ireland (IPH) contributed to the forum by giving a presentation on the day looking at ‘mortality, hospital admissions and self/carer reports of child unintentional injury in the Republic of Ireland from 2006-2015’, the report of which will be published by then end of 2016. The presentation provides contextual information about the occurrence of injuries and so is helpful to support the development of the Action Plan making some recommendations for policy focus and highlighting gaps in the research that need to be addressed.
Homoeopathic Management of Chronic Sinusitisijtsrd
Of all the respiratory tract infections, chronic sinusitis is one of the most common. It interferes with patient’s quality of life and loss of work productivity. It may affect 5 to 13 of the general population. Chronic sinusitis is most frequent disease seen in the clinical practice in middle age group and children. It is the fifth most common disease for which antibiotics are prescribed. Patients undergoing treatment with repeated courses of antibacterial agents and multiple sinus surgeries, have increased risk of colonization with antibiotic resistant pathogens and of surgical complications. Homoeopathic therapy is associated with improvement in a range of chronic and recurring pathologies or allergyand also strengthens immune system, thereby preventing recurrent attacks. Dr. Urmila Bhalgariya "Homoeopathic Management of Chronic Sinusitis" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-2 , February 2022, URL: https://www.ijtsrd.com/papers/ijtsrd49177.pdf Paper URL: https://www.ijtsrd.com/medicine/other/49177/homoeopathic-management-of-chronic-sinusitis/dr-urmila-bhalgariya
Similar to Statistical analysis of the health profile of Field ganj (Area C),Ludhiana ,India (11)
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
share - Lions, tigers, AI and health misinformation, oh my!.pptxTina Purnat
• Pitfalls and pivots needed to use AI effectively in public health
• Evidence-based strategies to address health misinformation effectively
• Building trust with communities online and offline
• Equipping health professionals to address questions, concerns and health misinformation
• Assessing risk and mitigating harm from adverse health narratives in communities, health workforce and health system
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
DISSERTATION on NEW DRUG DISCOVERY AND DEVELOPMENT STAGES OF DRUG DISCOVERYNEHA GUPTA
The process of drug discovery and development is a complex and multi-step endeavor aimed at bringing new pharmaceutical drugs to market. It begins with identifying and validating a biological target, such as a protein, gene, or RNA, that is associated with a disease. This step involves understanding the target's role in the disease and confirming that modulating it can have therapeutic effects. The next stage, hit identification, employs high-throughput screening (HTS) and other methods to find compounds that interact with the target. Computational techniques may also be used to identify potential hits from large compound libraries.
Following hit identification, the hits are optimized to improve their efficacy, selectivity, and pharmacokinetic properties, resulting in lead compounds. These leads undergo further refinement to enhance their potency, reduce toxicity, and improve drug-like characteristics, creating drug candidates suitable for preclinical testing. In the preclinical development phase, drug candidates are tested in vitro (in cell cultures) and in vivo (in animal models) to evaluate their safety, efficacy, pharmacokinetics, and pharmacodynamics. Toxicology studies are conducted to assess potential risks.
Before clinical trials can begin, an Investigational New Drug (IND) application must be submitted to regulatory authorities. This application includes data from preclinical studies and plans for clinical trials. Clinical development involves human trials in three phases: Phase I tests the drug's safety and dosage in a small group of healthy volunteers, Phase II assesses the drug's efficacy and side effects in a larger group of patients with the target disease, and Phase III confirms the drug's efficacy and monitors adverse reactions in a large population, often compared to existing treatments.
After successful clinical trials, a New Drug Application (NDA) is submitted to regulatory authorities for approval, including all data from preclinical and clinical studies, as well as proposed labeling and manufacturing information. Regulatory authorities then review the NDA to ensure the drug is safe, effective, and of high quality, potentially requiring additional studies. Finally, after a drug is approved and marketed, it undergoes post-marketing surveillance, which includes continuous monitoring for long-term safety and effectiveness, pharmacovigilance, and reporting of any adverse effects.
Antimicrobial stewardship to prevent antimicrobial resistanceGovindRankawat1
India is among the nations with the highest burden of bacterial infections.
India is one of the largest consumers of antibiotics worldwide.
India carries one of the largest burdens of drug‑resistant pathogens worldwide.
Highest burden of multidrug‑resistant tuberculosis,
Alarmingly high resistance among Gram‑negative and Gram‑positive bacteria even to newer antimicrobials such as carbapenems.
NDM‑1 ( New Delhi Metallo Beta lactamase 1, an enzyme which inactivates majority of Beta lactam antibiotics including carbapenems) was reported in 2008
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
17. 3rd Degree Malnourished Children
Sr No
Name
House No
Age/Sex
Birth Order
Immunization Weight
Status
(Kg)
1.
Vanshika
600
4/M
2
Complete-HiB 10
2.
Jatin
303
1.5/M
1
Complete-HiB 6.750
3.
Bhawana
141
3/F
1
Complete-HiB 9
4.
Vanshika
165
2/F
2
Complete-HiB 7.8
5.
Raghav
192
3/M
3
Complete-HiB 9
6.
Khushi
366
2.5/F
1
Complete-HiB 9
18. MATERNAL SERVICES
Old Antenatal mothers (a) 14
New antenatal mothers (b) 9
In coming mothers
(c ) 0
Deliveries and abortions(d) 3 & 1
Out going mothers (e) Total (a+b+c)- (d+e) 19
19. Baseline(Oct ‘12-Dec
‘12)
Total Deliveries
Protected with Tetanus Toxoid
Primigravidae
Multigravidae
Live Births
Twins
Still births
Abortions
Male
Female
Hospital Deliveries
Home Deliveries
TBA/ Dai
Nurse
Doctor
Relative/others
Total
21
21
20
0/0
1
1
21
Current Status(Mar ‘13Apr ‘13)
3
3
0
3
3
0/0
1
1
2
1
2
3
20. Due to deliver in next 3 months
S No Name
House No
Age
Gravid TT
High Risk
a
protectio factor if any
Parity n
EDD
Anu
440
23
P0+1
++
-
17 5/13
Neetu
246
22
Primi
++
-
June
Neetu
572
20
P0+1
++
-
June
Rajni
590
20
P1+0
++
-
June
1.
2.
3.
4.
21. Due to deliver in next 3 months
S No Name
House No
Age
Gravid TT
High Risk
a
protectio factor if any
Parity n
EDD
Tanu
240
23
Primi
++
-
July
Rosy
507
25
P1+0
++
-
July
Rajni
588
21
P1+0
++
-
July
Suman
602
20
P1+0
++
-
July
Tara Devi
328
33
P3+1
++
Anemic
July
1.
2.
3.
4.
5.
23. TB STATUS DURING THE POSTING
• Number of patients continuing from previous quarter- 14
• Number of patients newly diagnosed put on treatmentDOTS- 3
Non-DOTS- 0
•
•
•
•
•
Defaulters- 0
Relapse- 0
Treatment completed- 3
Transfer out- 0
Deaths- 0
24. Total patients currently on treatment-14
House
No.
Name
Age
Sex
DOTS
Provider
Category
Started on
Site
HIV
Screenin
g done
573
Mohit
34/
M
FG
I
27 7/12
Lung
Yes
639
Deepika 24/
F
FG
II
4 8/12
Ext-Pul
Yes
482
Tania
18/F FG
I
3 10/12
Lung
Yes
601
Sanjana 14/
F
II
2 11/12
Ext-Pul
Yes
FG
Contact
Screenin
g done
30. DEATHS IN THE COMMUNITY
H.No:
Name
Age/Sex
Cause of
death
Pre-existing Date of
morbidities death
Place of
death
203
B/o Kavita
4d/ M
Fetal
distress?
-
26 3/13
Hosp
371
Rakha Ram
99/ M
Shock/
Dyselectrol
ytemia
-
1 3/13
Home
642
Pritpal
75/M
Pneumonia
DM, Htn
15 3/13
Hosp
31. COMMONEST MORBIDITY IN THE COMMUNITYDIABETES MELLITUS
• Considered as heterogeneous group of diseases
characterized by chronic hyperglycemia
• Sugar cut-offs for FBS- 126 mg/dl, and for PPBS
200mg/dl, or RBS > 200 in presence of symptoms of
diabetes.
32. • Awareness regarding chronicity of the disease was provided
• Need for regular sugar checks, follow up, regular medication
was emphasized
• Stress was given on dose adjustment of various oral agents
• Knowledge regarding long term sequelae such as neuropathy,
retinopathy, effects on cardiovascular system was provided
• Importance of foot care, prevention of injuries to extremities
and eye check ups were explained
• Advice regarding diet control, high fiber diet was given
33. ACHIEVEMENTS DURING THE POSTING
• House visiting, communication skills
• Wound debridement, dressings
• I/M injections
• Journal presentation-Long term calcium intake and rates of all
cause and cardiovascular mortality: community based
prospective longitudinal cohort study
• Topic presentation- Gluten Sensitive Enteropathy Epidemiology and scope
• Participated in the Pulse polio program
• Pharmacy management
• Cash management