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Review of Spinal Injections
David P. Russo, DO, MPH
Board Certified PM&R/Pain Medicine
I can handle pain until it hurts.
-Woody Allen
Role of Interventional Care
 Incorporated into multidisciplinary care
 To confirm or treat a specific diagnosis
 To provide definitive palliation
 To assist in rehabilitation
 Primarily involved in mechanical spinal
and neuropathic pain
 Timing….
Spinal Anatomy
Spinal Anatomy
Spinal nerve
Sinuvertebral
nerve
Medial branch
Thecal sac
Lamina
Transverse
Process
Spinal Pain - Diagnosis
 Garbage in = Garbage out
 Better therapies come from more specific
diagnoses
 Myofascial
 Neuropathic
 Mechanical

Arthralgic

Discogenic
Myofascial
Spinal Pain
 May be primary or secondary
 Primary: most significant benefits from
functional/physical therapy approach
 Secondary: may require additional interventions
aimed at primary cause
 Trigger point injections
 Traditional, but little support in literature
 May assist with rehabilitation in some cases
 Role for botulinum toxin?
 Piriformis syndrome (Fishman LM. AJPM&R 2004;83:42-50)
Palpable taut bands
Radiate pain
Not fibromyalgia points
Neuropathic
Spinal Pain Considerations
 Acute radicular
 Transforaminal epidural steroid injection for
specific palliation/facilitation of rehabilitation
 Claudicatory
 Caudal, interlaminar, bilateral TFESI
 Sympathetic contribution
 Sympathetic nerve blocks
Epidural Steroid Injections
 Transforaminal 64480; 64483
 Interlaminar 62310; 62311
 Caudal 62311
Flouroscopic vs Blind Injections
 Flouroscopic guidance is the only way to ensure that
solution travels to the target location
 Flouroscopy decreases risk of complications
 Flouroscopic guidance is more effective than blind
injections
 Flouroscopy does have risks associated with radiation
exposure, though exposure is very limited
1
White AH, et al. Spine. 1980;5:78-86.
2
Stewart HD, et al. Br J Rheumatol. 1987;26:424-9.
3
Renfrew DL, et al. Am J Neuroradiol 1991:12:1003-7.
Epidural Steroid Injections
North American Spine Society. Clinical Guidelines for
Multidisciplinary Spine Care
Diagnosis and Treatment of Degenerative Lumbar Spinal
Stenosis. 2007
Transforaminal Epidural
Steroid Injection
Interlaminar ESI
Caudal Epidural Steroid Injections
 Effective for multilevel pathology including spinal stenosis
 Uses most volume of any approach
 Non-selective
 May be performed under flouroscopic guidance or blind
Caudal Epidurogram
Sympathetic Nerve Blocks
64520 or 64510
Lumbar Sympathetic Blocks Stellate Ganglion Block
Mechanical Spinal Pain:
Facet Arthropathy
 Synovial joints extend from C1-S1
 Subject to trauma & osteoarthritis
 Typical findings include pain on extension
and/or rotation of cervical or lumbar spine
 Lumbar: frequent cause of secondary
myofascial pain
 Cervical: frequent cause of “chronic whiplash”
Facet Joints:
A Source of Pain?
 Capsule & synovium
highly innervated
 Substance P
 VIP
 Bradykinin
 Neuropeptide Y
 Clinical studies
validate source of pain
McLain RF. Spine 1994;19(5):495-501
Beaman DN. Spine 1993;18(8):1044-49
Ashton IK. J Orth Res 1992;10(1):72-8
Facet Therapy 64490; 64493
 Fact Joint injections: Short-term palliative
 Diagnosis: medial branch nerve blocks
 Therapy: radiofrequency denervation
 Post-denervation physical therapy for
myofascial component
Kaplan M. Spine 1998;23(17):1847-52
Barnsely L. NEJM 1994; 330(15):1047-50
Carette S. NEJM 1991;325(14):1002-7
Dreyfuss P. Spine, 2000; 25(6):1270-77
Lord SM NEJM 1996;335:1721-6
Radiofrequency Facet
Denervation 64634, 64635
Cervical Medial Branch
Denervation
Lumbar Medial Branch
Blocks
Outcomes in Facet
Denervation
 75% treatment group: ≥ 50% relief of pain
 Median duration of relief ~ 422 days
 Psychological indicators improve
 Cost effective?
(Wallis BJ. Pain 1997;73:15-22)
(Lord SM NEJM 1996;335:1721-6}
(McDonald GJ Neurosurgery. 1999;45(1):61-7)
Sacroiliac Joint
Joint complex with both bone and soft tissue elements
SIJ Injections --20796
Used to diagnose and
treat pain of of lumbo-
pelvic origin.
Common source of “back
of the hip” or buttock pain
in older adults.
Common source of pain
patients with spinal
fusion.
Safety
 Post procedural pain, backache,
headache = 1-2%
 Dizziness, nausea, fainting = 0.5 – 1%
 Allergic reaction = 0.1%
 Bleeding complication = 1/1000-
1/10,000
 Neurological injury = 1/10,000 –
1/100,000

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Spinal_Injections_v2_LinkedIN

  • 1. Review of Spinal Injections David P. Russo, DO, MPH Board Certified PM&R/Pain Medicine
  • 2. I can handle pain until it hurts. -Woody Allen
  • 3. Role of Interventional Care  Incorporated into multidisciplinary care  To confirm or treat a specific diagnosis  To provide definitive palliation  To assist in rehabilitation  Primarily involved in mechanical spinal and neuropathic pain  Timing….
  • 4.
  • 6. Spinal Anatomy Spinal nerve Sinuvertebral nerve Medial branch Thecal sac Lamina Transverse Process
  • 7. Spinal Pain - Diagnosis  Garbage in = Garbage out  Better therapies come from more specific diagnoses  Myofascial  Neuropathic  Mechanical  Arthralgic  Discogenic
  • 8. Myofascial Spinal Pain  May be primary or secondary  Primary: most significant benefits from functional/physical therapy approach  Secondary: may require additional interventions aimed at primary cause  Trigger point injections  Traditional, but little support in literature  May assist with rehabilitation in some cases  Role for botulinum toxin?  Piriformis syndrome (Fishman LM. AJPM&R 2004;83:42-50)
  • 9. Palpable taut bands Radiate pain Not fibromyalgia points
  • 10. Neuropathic Spinal Pain Considerations  Acute radicular  Transforaminal epidural steroid injection for specific palliation/facilitation of rehabilitation  Claudicatory  Caudal, interlaminar, bilateral TFESI  Sympathetic contribution  Sympathetic nerve blocks
  • 11. Epidural Steroid Injections  Transforaminal 64480; 64483  Interlaminar 62310; 62311  Caudal 62311
  • 12. Flouroscopic vs Blind Injections  Flouroscopic guidance is the only way to ensure that solution travels to the target location  Flouroscopy decreases risk of complications  Flouroscopic guidance is more effective than blind injections  Flouroscopy does have risks associated with radiation exposure, though exposure is very limited 1 White AH, et al. Spine. 1980;5:78-86. 2 Stewart HD, et al. Br J Rheumatol. 1987;26:424-9. 3 Renfrew DL, et al. Am J Neuroradiol 1991:12:1003-7.
  • 13. Epidural Steroid Injections North American Spine Society. Clinical Guidelines for Multidisciplinary Spine Care Diagnosis and Treatment of Degenerative Lumbar Spinal Stenosis. 2007
  • 16. Caudal Epidural Steroid Injections  Effective for multilevel pathology including spinal stenosis  Uses most volume of any approach  Non-selective  May be performed under flouroscopic guidance or blind
  • 18. Sympathetic Nerve Blocks 64520 or 64510 Lumbar Sympathetic Blocks Stellate Ganglion Block
  • 19. Mechanical Spinal Pain: Facet Arthropathy  Synovial joints extend from C1-S1  Subject to trauma & osteoarthritis  Typical findings include pain on extension and/or rotation of cervical or lumbar spine  Lumbar: frequent cause of secondary myofascial pain  Cervical: frequent cause of “chronic whiplash”
  • 20. Facet Joints: A Source of Pain?  Capsule & synovium highly innervated  Substance P  VIP  Bradykinin  Neuropeptide Y  Clinical studies validate source of pain McLain RF. Spine 1994;19(5):495-501 Beaman DN. Spine 1993;18(8):1044-49 Ashton IK. J Orth Res 1992;10(1):72-8
  • 21. Facet Therapy 64490; 64493  Fact Joint injections: Short-term palliative  Diagnosis: medial branch nerve blocks  Therapy: radiofrequency denervation  Post-denervation physical therapy for myofascial component Kaplan M. Spine 1998;23(17):1847-52 Barnsely L. NEJM 1994; 330(15):1047-50 Carette S. NEJM 1991;325(14):1002-7 Dreyfuss P. Spine, 2000; 25(6):1270-77 Lord SM NEJM 1996;335:1721-6
  • 22. Radiofrequency Facet Denervation 64634, 64635 Cervical Medial Branch Denervation Lumbar Medial Branch Blocks
  • 23. Outcomes in Facet Denervation  75% treatment group: ≥ 50% relief of pain  Median duration of relief ~ 422 days  Psychological indicators improve  Cost effective? (Wallis BJ. Pain 1997;73:15-22) (Lord SM NEJM 1996;335:1721-6} (McDonald GJ Neurosurgery. 1999;45(1):61-7)
  • 24. Sacroiliac Joint Joint complex with both bone and soft tissue elements
  • 25. SIJ Injections --20796 Used to diagnose and treat pain of of lumbo- pelvic origin. Common source of “back of the hip” or buttock pain in older adults. Common source of pain patients with spinal fusion.
  • 26. Safety  Post procedural pain, backache, headache = 1-2%  Dizziness, nausea, fainting = 0.5 – 1%  Allergic reaction = 0.1%  Bleeding complication = 1/1000- 1/10,000  Neurological injury = 1/10,000 – 1/100,000

Editor's Notes

  1. For our patient’s who don’t respond, or continue to have symptoms, despite oral agents and physical therapy, an injection might be appropriate. There is some debate over the use of epidural steroid injections and I hope I can provide some insight. Let me start by saying that all epidurals are not the same. In general, medication can be directed to the epidural space using one of three routes: 1) caudally, through the sacral canal; interlaminar, through the posterior muscles and ligaments to the dorsal (posterior) epidural space; and 3) transforaminally, through the intervertebral foramen to the ventral (anterior) epidural space. The first two approaches may be done with or without flouroscopic guidance; a transforaminal approach requires the use of flouroscopy.