SlideShare a Scribd company logo
1 of 27
Download to read offline
Application of different
species & strains of animals
Presented by
A. Gowtham Sashtha 1st M.pharm
Department of pharmacology
K.M College of pharmacy Madurai - 625107.
Introduction :
➜Choice of species is largely determined by the nature
of the experiment, available facilities and the suitability
for a particular type of research.
➜Anyone using mice or rats also has the choice of
many strains.
Types of species & Strain :
Animal species :
➜Mice
➜ Rat
➜Fish
➜Birds
➜Guinea pig
➜Rabbit
➜Dogs
➜Non human primates
Animals strains :
➜Isogenic Strains
➜Mutants strains
➜Transgenic strains
➜"Knockout" Strains
Types of animal strains in mice & rat
Isogenic Strains :
➜Inbred strains or F1 (first generation)
➜Defined as a product of over 20 generation of
brother sister matings which results in indivituals that are
98% identical to each other's
➜After 40 generation og det inbreeding they are
99.5% similar. in other words, they are almost clones.
➜As animals maintained at different institutions for
many generations may show genetic drift,even though
they originate from the same source.
Mutants strains :
➜Many mutations have arisen in mouse and, to a
lesser extent, in rat colonies either spontaneously or as a
result of irradiation or chemical treatment.
➜For example mutant athymic “nude” mice and rats
have a defective cell mediated immune system and will
grow human tumour xenografts.
➜Various obese mutations have made a fundamental
contribution to our understanding of obesity and
metabolism.
Transgenic strains :
➜Transgenic strains are most commonly used in
mice.
➜These strains are made by the incorporation of
DNA from another source into the genome.
➜This is usually done by microinjection into an early
embryo.
➜The aim is usually to get an animal to express a
foreign gene.
Knockout strains :
➜These are strains in which one or more host genes
have been inactivated either altogether or in a particular
tissue or at a particular time.
➜This technique used to obtain this strain (deletion,
disruption, promoter inactivation).
Animals used in laboratory research :
Mouse (Mus musculus )
➜Mice is used in a variety
of other types of research,
including cancer, immunology,
toxicology, metabolism,
developmental biology, diabetes,
obesity, aging, and
cardiovascular research.
Rat (Rattus norvegicus)
➜While less commonly
used for research than mice,
rats have served as an
important animal model for
research in psychology and
biomedical science.
Guinea pig (Cavia Porcellus)
➜Today, guinea pigs are still
widely used in medical research,
particularly in the study of
respiratory, nervous and immune
systems.
➜Gerbils and guinea pigs have a
similar hearing range to humans
which makes them a useful model
for understanding how our ears
work and how they can be repaired.
Rabbit(Oryctolagus cuniculus)
➜Rabbits are also used in
experiments to study
cardiovascular disease, skin
conditions, and spinal cord injuries.
➜The surgically mutilated
animals were observed for 24
weeks and then killed.
THANK YOU
Zoho Show
To create beautiful presentations, download Zoho Show from Play Store
https://zoho.to/cy7
species and strains of animals.pdf
(This PDF has been generated using Zoho Show)

More Related Content

What's hot

Routes of drug administration
Routes of drug administrationRoutes of drug administration
Routes of drug administrationDr Ajay Mandal
 
Screening of centrally acting muscle relaxant agents
Screening of centrally acting muscle relaxant agentsScreening of centrally acting muscle relaxant agents
Screening of centrally acting muscle relaxant agentsDeepmalya Ghosh
 
Screening of Drugs acting on ANS
Screening of Drugs acting on ANSScreening of Drugs acting on ANS
Screening of Drugs acting on ANSJaineel Dharod
 
Screening of Dyslipidemic drugs
Screening of Dyslipidemic drugsScreening of Dyslipidemic drugs
Screening of Dyslipidemic drugsPavana K A
 
Scale up of liquid orals
Scale up of liquid orals Scale up of liquid orals
Scale up of liquid orals Parag Behura
 
Antidiabetic screening
Antidiabetic screeningAntidiabetic screening
Antidiabetic screeningnazuk sharma
 
SCREENING OF ANTI CANCER DRUGS
SCREENING OF ANTI CANCER DRUGSSCREENING OF ANTI CANCER DRUGS
SCREENING OF ANTI CANCER DRUGSRafa Zubair
 
Moving Boundary & Isoelctric focusing(JEEV).pptx
Moving Boundary & Isoelctric focusing(JEEV).pptxMoving Boundary & Isoelctric focusing(JEEV).pptx
Moving Boundary & Isoelctric focusing(JEEV).pptxSHREYAL7
 
Screening of antihypertensive agents
Screening of antihypertensive agentsScreening of antihypertensive agents
Screening of antihypertensive agentsKanthlal SK
 
screening of ans drugs
screening of ans drugsscreening of ans drugs
screening of ans drugsSrota Dawn
 
Evaluation methods of anti-asthmatics
Evaluation methods of anti-asthmaticsEvaluation methods of anti-asthmatics
Evaluation methods of anti-asthmaticsNovo Nordisk India
 
Multi component analysis (uv visible spectroscopy) by mr. pradeep swarnkar)
Multi component analysis (uv visible spectroscopy) by mr. pradeep swarnkar)Multi component analysis (uv visible spectroscopy) by mr. pradeep swarnkar)
Multi component analysis (uv visible spectroscopy) by mr. pradeep swarnkar)Pradeep Swarnkar
 
In Vitro Anti Inflammatory and Anti Arthritic Activity of Commelina benghalen...
In Vitro Anti Inflammatory and Anti Arthritic Activity of Commelina benghalen...In Vitro Anti Inflammatory and Anti Arthritic Activity of Commelina benghalen...
In Vitro Anti Inflammatory and Anti Arthritic Activity of Commelina benghalen...SriramNagarajan16
 

What's hot (20)

OECD Guidelines
OECD GuidelinesOECD Guidelines
OECD Guidelines
 
Routes of drug administration
Routes of drug administrationRoutes of drug administration
Routes of drug administration
 
Screening of centrally acting muscle relaxant agents
Screening of centrally acting muscle relaxant agentsScreening of centrally acting muscle relaxant agents
Screening of centrally acting muscle relaxant agents
 
Screening of Drugs acting on ANS
Screening of Drugs acting on ANSScreening of Drugs acting on ANS
Screening of Drugs acting on ANS
 
Screening models of Anti diabetics.
Screening models of Anti diabetics.Screening models of Anti diabetics.
Screening models of Anti diabetics.
 
Screening of Dyslipidemic drugs
Screening of Dyslipidemic drugsScreening of Dyslipidemic drugs
Screening of Dyslipidemic drugs
 
Scale up of liquid orals
Scale up of liquid orals Scale up of liquid orals
Scale up of liquid orals
 
Antidiabetic screening
Antidiabetic screeningAntidiabetic screening
Antidiabetic screening
 
SCREENING OF ANTI CANCER DRUGS
SCREENING OF ANTI CANCER DRUGSSCREENING OF ANTI CANCER DRUGS
SCREENING OF ANTI CANCER DRUGS
 
Moving Boundary & Isoelctric focusing(JEEV).pptx
Moving Boundary & Isoelctric focusing(JEEV).pptxMoving Boundary & Isoelctric focusing(JEEV).pptx
Moving Boundary & Isoelctric focusing(JEEV).pptx
 
Screening of antihypertensive agents
Screening of antihypertensive agentsScreening of antihypertensive agents
Screening of antihypertensive agents
 
Anaesthesia and euthanasia
Anaesthesia and euthanasiaAnaesthesia and euthanasia
Anaesthesia and euthanasia
 
Screening of antidepressant
Screening of antidepressantScreening of antidepressant
Screening of antidepressant
 
screening of ans drugs
screening of ans drugsscreening of ans drugs
screening of ans drugs
 
Evaluation methods of anti-asthmatics
Evaluation methods of anti-asthmaticsEvaluation methods of anti-asthmatics
Evaluation methods of anti-asthmatics
 
Multi component analysis (uv visible spectroscopy) by mr. pradeep swarnkar)
Multi component analysis (uv visible spectroscopy) by mr. pradeep swarnkar)Multi component analysis (uv visible spectroscopy) by mr. pradeep swarnkar)
Multi component analysis (uv visible spectroscopy) by mr. pradeep swarnkar)
 
Concept of non linear and linear pharmacokinetic model
Concept of non linear and linear pharmacokinetic modelConcept of non linear and linear pharmacokinetic model
Concept of non linear and linear pharmacokinetic model
 
In Vitro Anti Inflammatory and Anti Arthritic Activity of Commelina benghalen...
In Vitro Anti Inflammatory and Anti Arthritic Activity of Commelina benghalen...In Vitro Anti Inflammatory and Anti Arthritic Activity of Commelina benghalen...
In Vitro Anti Inflammatory and Anti Arthritic Activity of Commelina benghalen...
 
ICH Safety Guidelines
ICH Safety GuidelinesICH Safety Guidelines
ICH Safety Guidelines
 
Alternative animal experimentation technique
Alternative animal experimentation techniqueAlternative animal experimentation technique
Alternative animal experimentation technique
 

Similar to Different species & Strains of animals

Development of animal model (Knockout Mice)
Development of animal model   (Knockout Mice)Development of animal model   (Knockout Mice)
Development of animal model (Knockout Mice)AnilBehera8
 
Transgenic and genome edited animals
Transgenic and genome edited animalsTransgenic and genome edited animals
Transgenic and genome edited animalsTamannaAntil1
 
Transgenic animals
Transgenic animalsTransgenic animals
Transgenic animalsBruno Mmassy
 
Presentation 25th aug 2014
Presentation 25th aug 2014Presentation 25th aug 2014
Presentation 25th aug 2014Suman Manandhar
 
Experimental animal models ( lab animals )
Experimental animal models ( lab animals )Experimental animal models ( lab animals )
Experimental animal models ( lab animals )ebrahem elalfy
 
Experimental animal models ( lab animals )
Experimental animal models ( lab animals )Experimental animal models ( lab animals )
Experimental animal models ( lab animals )ebrahem elalfy
 
common_Lab_animal_and_breeding_colonies-1.pptx
common_Lab_animal_and_breeding_colonies-1.pptxcommon_Lab_animal_and_breeding_colonies-1.pptx
common_Lab_animal_and_breeding_colonies-1.pptxMohammad Ahmed Khan
 
Summer 2015 poster
Summer 2015 posterSummer 2015 poster
Summer 2015 posterRobert Hwang
 
Transgenic-pigs- trilok.pptx
Transgenic-pigs- trilok.pptxTransgenic-pigs- trilok.pptx
Transgenic-pigs- trilok.pptxTrilokMandal2
 
Transgenesis by Dr.Ashwini J. Patel-Gujarat
Transgenesis by Dr.Ashwini J. Patel-GujaratTransgenesis by Dr.Ashwini J. Patel-Gujarat
Transgenesis by Dr.Ashwini J. Patel-GujaratDr. ASHWINI PATEL
 
Science project for justinian
Science  project for justinianScience  project for justinian
Science project for justinianMorganScience
 
Genetic engineering2
Genetic engineering2Genetic engineering2
Genetic engineering2scoville
 
Genetic engineering2
Genetic engineering2Genetic engineering2
Genetic engineering2scoville
 

Similar to Different species & Strains of animals (20)

TRANSGENIC ANIMALS
TRANSGENIC ANIMALSTRANSGENIC ANIMALS
TRANSGENIC ANIMALS
 
Chromosome manipulations
Chromosome manipulationsChromosome manipulations
Chromosome manipulations
 
Development of animal model (Knockout Mice)
Development of animal model   (Knockout Mice)Development of animal model   (Knockout Mice)
Development of animal model (Knockout Mice)
 
Transgenic and genome edited animals
Transgenic and genome edited animalsTransgenic and genome edited animals
Transgenic and genome edited animals
 
Transgenic animals
Transgenic animalsTransgenic animals
Transgenic animals
 
Presentation 25th aug 2014
Presentation 25th aug 2014Presentation 25th aug 2014
Presentation 25th aug 2014
 
Transgenic animal
Transgenic animalTransgenic animal
Transgenic animal
 
Experimental animal models ( lab animals )
Experimental animal models ( lab animals )Experimental animal models ( lab animals )
Experimental animal models ( lab animals )
 
Experimental animal models ( lab animals )
Experimental animal models ( lab animals )Experimental animal models ( lab animals )
Experimental animal models ( lab animals )
 
common_Lab_animal_and_breeding_colonies-1.pptx
common_Lab_animal_and_breeding_colonies-1.pptxcommon_Lab_animal_and_breeding_colonies-1.pptx
common_Lab_animal_and_breeding_colonies-1.pptx
 
Summer 2015 poster
Summer 2015 posterSummer 2015 poster
Summer 2015 poster
 
Transgenic-pigs- trilok.pptx
Transgenic-pigs- trilok.pptxTransgenic-pigs- trilok.pptx
Transgenic-pigs- trilok.pptx
 
Transgenesis by Dr.Ashwini J. Patel-Gujarat
Transgenesis by Dr.Ashwini J. Patel-GujaratTransgenesis by Dr.Ashwini J. Patel-Gujarat
Transgenesis by Dr.Ashwini J. Patel-Gujarat
 
Mouse model: Pros & Cons
Mouse model: Pros & ConsMouse model: Pros & Cons
Mouse model: Pros & Cons
 
Science project for justinian
Science  project for justinianScience  project for justinian
Science project for justinian
 
Model organisms
Model organismsModel organisms
Model organisms
 
Transgenic technology
Transgenic technologyTransgenic technology
Transgenic technology
 
Genetic engineering2
Genetic engineering2Genetic engineering2
Genetic engineering2
 
Genetic engineering2
Genetic engineering2Genetic engineering2
Genetic engineering2
 
Cloning
Cloning  Cloning
Cloning
 

More from A. Gowtham Sashtha

Screening Methods of Analgesics Agents...
Screening Methods of Analgesics Agents...Screening Methods of Analgesics Agents...
Screening Methods of Analgesics Agents...A. Gowtham Sashtha
 
Screening Methods of Anti-epileptic drugs
Screening Methods of Anti-epileptic drugsScreening Methods of Anti-epileptic drugs
Screening Methods of Anti-epileptic drugsA. Gowtham Sashtha
 
Hypertesion & Anti-Hypertensive drugs
Hypertesion & Anti-Hypertensive drugsHypertesion & Anti-Hypertensive drugs
Hypertesion & Anti-Hypertensive drugsA. Gowtham Sashtha
 
Epilepsy and Anti epileptic drugs
Epilepsy and Anti epileptic drugsEpilepsy and Anti epileptic drugs
Epilepsy and Anti epileptic drugsA. Gowtham Sashtha
 
Acetylcholine Neurotransmitter
Acetylcholine Neurotransmitter Acetylcholine Neurotransmitter
Acetylcholine Neurotransmitter A. Gowtham Sashtha
 

More from A. Gowtham Sashtha (7)

Screening Methods of Analgesics Agents...
Screening Methods of Analgesics Agents...Screening Methods of Analgesics Agents...
Screening Methods of Analgesics Agents...
 
Screening Methods of Anti-epileptic drugs
Screening Methods of Anti-epileptic drugsScreening Methods of Anti-epileptic drugs
Screening Methods of Anti-epileptic drugs
 
Fibrinolytics drugs.
Fibrinolytics drugs.Fibrinolytics drugs.
Fibrinolytics drugs.
 
Hypertesion & Anti-Hypertensive drugs
Hypertesion & Anti-Hypertensive drugsHypertesion & Anti-Hypertensive drugs
Hypertesion & Anti-Hypertensive drugs
 
Epilepsy and Anti epileptic drugs
Epilepsy and Anti epileptic drugsEpilepsy and Anti epileptic drugs
Epilepsy and Anti epileptic drugs
 
Glycine Neurotransmitter
Glycine Neurotransmitter Glycine Neurotransmitter
Glycine Neurotransmitter
 
Acetylcholine Neurotransmitter
Acetylcholine Neurotransmitter Acetylcholine Neurotransmitter
Acetylcholine Neurotransmitter
 

Recently uploaded

Shark introduction Morphology and its behaviour characteristics
Shark introduction Morphology and its behaviour characteristicsShark introduction Morphology and its behaviour characteristics
Shark introduction Morphology and its behaviour characteristicsArubSultan
 
DBMSArchitecture_QueryProcessingandOptimization.pdf
DBMSArchitecture_QueryProcessingandOptimization.pdfDBMSArchitecture_QueryProcessingandOptimization.pdf
DBMSArchitecture_QueryProcessingandOptimization.pdfChristalin Nelson
 
Team Lead Succeed – Helping you and your team achieve high-performance teamwo...
Team Lead Succeed – Helping you and your team achieve high-performance teamwo...Team Lead Succeed – Helping you and your team achieve high-performance teamwo...
Team Lead Succeed – Helping you and your team achieve high-performance teamwo...Association for Project Management
 
Grade Three -ELLNA-REVIEWER-ENGLISH.pptx
Grade Three -ELLNA-REVIEWER-ENGLISH.pptxGrade Three -ELLNA-REVIEWER-ENGLISH.pptx
Grade Three -ELLNA-REVIEWER-ENGLISH.pptxkarenfajardo43
 
Mythology Quiz-4th April 2024, Quiz Club NITW
Mythology Quiz-4th April 2024, Quiz Club NITWMythology Quiz-4th April 2024, Quiz Club NITW
Mythology Quiz-4th April 2024, Quiz Club NITWQuiz Club NITW
 
ICS 2208 Lecture Slide Notes for Topic 6
ICS 2208 Lecture Slide Notes for Topic 6ICS 2208 Lecture Slide Notes for Topic 6
ICS 2208 Lecture Slide Notes for Topic 6Vanessa Camilleri
 
Satirical Depths - A Study of Gabriel Okara's Poem - 'You Laughed and Laughed...
Satirical Depths - A Study of Gabriel Okara's Poem - 'You Laughed and Laughed...Satirical Depths - A Study of Gabriel Okara's Poem - 'You Laughed and Laughed...
Satirical Depths - A Study of Gabriel Okara's Poem - 'You Laughed and Laughed...HetalPathak10
 
31 ĐỀ THI THỬ VÀO LỚP 10 - TIẾNG ANH - FORM MỚI 2025 - 40 CÂU HỎI - BÙI VĂN V...
31 ĐỀ THI THỬ VÀO LỚP 10 - TIẾNG ANH - FORM MỚI 2025 - 40 CÂU HỎI - BÙI VĂN V...31 ĐỀ THI THỬ VÀO LỚP 10 - TIẾNG ANH - FORM MỚI 2025 - 40 CÂU HỎI - BÙI VĂN V...
31 ĐỀ THI THỬ VÀO LỚP 10 - TIẾNG ANH - FORM MỚI 2025 - 40 CÂU HỎI - BÙI VĂN V...Nguyen Thanh Tu Collection
 
6 ways Samsung’s Interactive Display powered by Android changes the classroom
6 ways Samsung’s Interactive Display powered by Android changes the classroom6 ways Samsung’s Interactive Display powered by Android changes the classroom
6 ways Samsung’s Interactive Display powered by Android changes the classroomSamsung Business USA
 
CHUYÊN ĐỀ ÔN THEO CÂU CHO HỌC SINH LỚP 12 ĐỂ ĐẠT ĐIỂM 5+ THI TỐT NGHIỆP THPT ...
CHUYÊN ĐỀ ÔN THEO CÂU CHO HỌC SINH LỚP 12 ĐỂ ĐẠT ĐIỂM 5+ THI TỐT NGHIỆP THPT ...CHUYÊN ĐỀ ÔN THEO CÂU CHO HỌC SINH LỚP 12 ĐỂ ĐẠT ĐIỂM 5+ THI TỐT NGHIỆP THPT ...
CHUYÊN ĐỀ ÔN THEO CÂU CHO HỌC SINH LỚP 12 ĐỂ ĐẠT ĐIỂM 5+ THI TỐT NGHIỆP THPT ...Nguyen Thanh Tu Collection
 
CLASSIFICATION OF ANTI - CANCER DRUGS.pptx
CLASSIFICATION OF ANTI - CANCER DRUGS.pptxCLASSIFICATION OF ANTI - CANCER DRUGS.pptx
CLASSIFICATION OF ANTI - CANCER DRUGS.pptxAnupam32727
 
ClimART Action | eTwinning Project
ClimART Action    |    eTwinning ProjectClimART Action    |    eTwinning Project
ClimART Action | eTwinning Projectjordimapav
 
Q-Factor HISPOL Quiz-6th April 2024, Quiz Club NITW
Q-Factor HISPOL Quiz-6th April 2024, Quiz Club NITWQ-Factor HISPOL Quiz-6th April 2024, Quiz Club NITW
Q-Factor HISPOL Quiz-6th April 2024, Quiz Club NITWQuiz Club NITW
 
BÀI TẬP BỔ TRỢ TIẾNG ANH 8 - I-LEARN SMART WORLD - CẢ NĂM - CÓ FILE NGHE (BẢN...
BÀI TẬP BỔ TRỢ TIẾNG ANH 8 - I-LEARN SMART WORLD - CẢ NĂM - CÓ FILE NGHE (BẢN...BÀI TẬP BỔ TRỢ TIẾNG ANH 8 - I-LEARN SMART WORLD - CẢ NĂM - CÓ FILE NGHE (BẢN...
BÀI TẬP BỔ TRỢ TIẾNG ANH 8 - I-LEARN SMART WORLD - CẢ NĂM - CÓ FILE NGHE (BẢN...Nguyen Thanh Tu Collection
 
Blowin' in the Wind of Caste_ Bob Dylan's Song as a Catalyst for Social Justi...
Blowin' in the Wind of Caste_ Bob Dylan's Song as a Catalyst for Social Justi...Blowin' in the Wind of Caste_ Bob Dylan's Song as a Catalyst for Social Justi...
Blowin' in the Wind of Caste_ Bob Dylan's Song as a Catalyst for Social Justi...DhatriParmar
 
Scientific Writing :Research Discourse
Scientific  Writing :Research  DiscourseScientific  Writing :Research  Discourse
Scientific Writing :Research DiscourseAnita GoswamiGiri
 
Tree View Decoration Attribute in the Odoo 17
Tree View Decoration Attribute in the Odoo 17Tree View Decoration Attribute in the Odoo 17
Tree View Decoration Attribute in the Odoo 17Celine George
 

Recently uploaded (20)

Shark introduction Morphology and its behaviour characteristics
Shark introduction Morphology and its behaviour characteristicsShark introduction Morphology and its behaviour characteristics
Shark introduction Morphology and its behaviour characteristics
 
DBMSArchitecture_QueryProcessingandOptimization.pdf
DBMSArchitecture_QueryProcessingandOptimization.pdfDBMSArchitecture_QueryProcessingandOptimization.pdf
DBMSArchitecture_QueryProcessingandOptimization.pdf
 
Team Lead Succeed – Helping you and your team achieve high-performance teamwo...
Team Lead Succeed – Helping you and your team achieve high-performance teamwo...Team Lead Succeed – Helping you and your team achieve high-performance teamwo...
Team Lead Succeed – Helping you and your team achieve high-performance teamwo...
 
Grade Three -ELLNA-REVIEWER-ENGLISH.pptx
Grade Three -ELLNA-REVIEWER-ENGLISH.pptxGrade Three -ELLNA-REVIEWER-ENGLISH.pptx
Grade Three -ELLNA-REVIEWER-ENGLISH.pptx
 
CARNAVAL COM MAGIA E EUFORIA _
CARNAVAL COM MAGIA E EUFORIA            _CARNAVAL COM MAGIA E EUFORIA            _
CARNAVAL COM MAGIA E EUFORIA _
 
Spearman's correlation,Formula,Advantages,
Spearman's correlation,Formula,Advantages,Spearman's correlation,Formula,Advantages,
Spearman's correlation,Formula,Advantages,
 
Mythology Quiz-4th April 2024, Quiz Club NITW
Mythology Quiz-4th April 2024, Quiz Club NITWMythology Quiz-4th April 2024, Quiz Club NITW
Mythology Quiz-4th April 2024, Quiz Club NITW
 
ICS 2208 Lecture Slide Notes for Topic 6
ICS 2208 Lecture Slide Notes for Topic 6ICS 2208 Lecture Slide Notes for Topic 6
ICS 2208 Lecture Slide Notes for Topic 6
 
Satirical Depths - A Study of Gabriel Okara's Poem - 'You Laughed and Laughed...
Satirical Depths - A Study of Gabriel Okara's Poem - 'You Laughed and Laughed...Satirical Depths - A Study of Gabriel Okara's Poem - 'You Laughed and Laughed...
Satirical Depths - A Study of Gabriel Okara's Poem - 'You Laughed and Laughed...
 
31 ĐỀ THI THỬ VÀO LỚP 10 - TIẾNG ANH - FORM MỚI 2025 - 40 CÂU HỎI - BÙI VĂN V...
31 ĐỀ THI THỬ VÀO LỚP 10 - TIẾNG ANH - FORM MỚI 2025 - 40 CÂU HỎI - BÙI VĂN V...31 ĐỀ THI THỬ VÀO LỚP 10 - TIẾNG ANH - FORM MỚI 2025 - 40 CÂU HỎI - BÙI VĂN V...
31 ĐỀ THI THỬ VÀO LỚP 10 - TIẾNG ANH - FORM MỚI 2025 - 40 CÂU HỎI - BÙI VĂN V...
 
6 ways Samsung’s Interactive Display powered by Android changes the classroom
6 ways Samsung’s Interactive Display powered by Android changes the classroom6 ways Samsung’s Interactive Display powered by Android changes the classroom
6 ways Samsung’s Interactive Display powered by Android changes the classroom
 
CHUYÊN ĐỀ ÔN THEO CÂU CHO HỌC SINH LỚP 12 ĐỂ ĐẠT ĐIỂM 5+ THI TỐT NGHIỆP THPT ...
CHUYÊN ĐỀ ÔN THEO CÂU CHO HỌC SINH LỚP 12 ĐỂ ĐẠT ĐIỂM 5+ THI TỐT NGHIỆP THPT ...CHUYÊN ĐỀ ÔN THEO CÂU CHO HỌC SINH LỚP 12 ĐỂ ĐẠT ĐIỂM 5+ THI TỐT NGHIỆP THPT ...
CHUYÊN ĐỀ ÔN THEO CÂU CHO HỌC SINH LỚP 12 ĐỂ ĐẠT ĐIỂM 5+ THI TỐT NGHIỆP THPT ...
 
CLASSIFICATION OF ANTI - CANCER DRUGS.pptx
CLASSIFICATION OF ANTI - CANCER DRUGS.pptxCLASSIFICATION OF ANTI - CANCER DRUGS.pptx
CLASSIFICATION OF ANTI - CANCER DRUGS.pptx
 
ClimART Action | eTwinning Project
ClimART Action    |    eTwinning ProjectClimART Action    |    eTwinning Project
ClimART Action | eTwinning Project
 
Q-Factor HISPOL Quiz-6th April 2024, Quiz Club NITW
Q-Factor HISPOL Quiz-6th April 2024, Quiz Club NITWQ-Factor HISPOL Quiz-6th April 2024, Quiz Club NITW
Q-Factor HISPOL Quiz-6th April 2024, Quiz Club NITW
 
Mattingly "AI & Prompt Design" - Introduction to Machine Learning"
Mattingly "AI & Prompt Design" - Introduction to Machine Learning"Mattingly "AI & Prompt Design" - Introduction to Machine Learning"
Mattingly "AI & Prompt Design" - Introduction to Machine Learning"
 
BÀI TẬP BỔ TRỢ TIẾNG ANH 8 - I-LEARN SMART WORLD - CẢ NĂM - CÓ FILE NGHE (BẢN...
BÀI TẬP BỔ TRỢ TIẾNG ANH 8 - I-LEARN SMART WORLD - CẢ NĂM - CÓ FILE NGHE (BẢN...BÀI TẬP BỔ TRỢ TIẾNG ANH 8 - I-LEARN SMART WORLD - CẢ NĂM - CÓ FILE NGHE (BẢN...
BÀI TẬP BỔ TRỢ TIẾNG ANH 8 - I-LEARN SMART WORLD - CẢ NĂM - CÓ FILE NGHE (BẢN...
 
Blowin' in the Wind of Caste_ Bob Dylan's Song as a Catalyst for Social Justi...
Blowin' in the Wind of Caste_ Bob Dylan's Song as a Catalyst for Social Justi...Blowin' in the Wind of Caste_ Bob Dylan's Song as a Catalyst for Social Justi...
Blowin' in the Wind of Caste_ Bob Dylan's Song as a Catalyst for Social Justi...
 
Scientific Writing :Research Discourse
Scientific  Writing :Research  DiscourseScientific  Writing :Research  Discourse
Scientific Writing :Research Discourse
 
Tree View Decoration Attribute in the Odoo 17
Tree View Decoration Attribute in the Odoo 17Tree View Decoration Attribute in the Odoo 17
Tree View Decoration Attribute in the Odoo 17
 

Different species & Strains of animals

  • 1. Application of different species & strains of animals Presented by A. Gowtham Sashtha 1st M.pharm Department of pharmacology K.M College of pharmacy Madurai - 625107.
  • 2. Introduction : ➜Choice of species is largely determined by the nature of the experiment, available facilities and the suitability for a particular type of research. ➜Anyone using mice or rats also has the choice of many strains.
  • 3. Types of species & Strain : Animal species : ➜Mice ➜ Rat ➜Fish ➜Birds ➜Guinea pig ➜Rabbit ➜Dogs ➜Non human primates Animals strains : ➜Isogenic Strains ➜Mutants strains ➜Transgenic strains ➜"Knockout" Strains
  • 4. Types of animal strains in mice & rat
  • 5. Isogenic Strains : ➜Inbred strains or F1 (first generation) ➜Defined as a product of over 20 generation of brother sister matings which results in indivituals that are 98% identical to each other's ➜After 40 generation og det inbreeding they are 99.5% similar. in other words, they are almost clones. ➜As animals maintained at different institutions for many generations may show genetic drift,even though they originate from the same source.
  • 6.
  • 7. Mutants strains : ➜Many mutations have arisen in mouse and, to a lesser extent, in rat colonies either spontaneously or as a result of irradiation or chemical treatment. ➜For example mutant athymic “nude” mice and rats have a defective cell mediated immune system and will grow human tumour xenografts. ➜Various obese mutations have made a fundamental contribution to our understanding of obesity and metabolism.
  • 8.
  • 9. Transgenic strains : ➜Transgenic strains are most commonly used in mice. ➜These strains are made by the incorporation of DNA from another source into the genome. ➜This is usually done by microinjection into an early embryo. ➜The aim is usually to get an animal to express a foreign gene.
  • 10.
  • 11. Knockout strains : ➜These are strains in which one or more host genes have been inactivated either altogether or in a particular tissue or at a particular time. ➜This technique used to obtain this strain (deletion, disruption, promoter inactivation).
  • 12.
  • 13.
  • 14. Animals used in laboratory research :
  • 15. Mouse (Mus musculus ) ➜Mice is used in a variety of other types of research, including cancer, immunology, toxicology, metabolism, developmental biology, diabetes, obesity, aging, and cardiovascular research.
  • 16.
  • 17.
  • 18. Rat (Rattus norvegicus) ➜While less commonly used for research than mice, rats have served as an important animal model for research in psychology and biomedical science.
  • 19.
  • 20.
  • 21. Guinea pig (Cavia Porcellus) ➜Today, guinea pigs are still widely used in medical research, particularly in the study of respiratory, nervous and immune systems. ➜Gerbils and guinea pigs have a similar hearing range to humans which makes them a useful model for understanding how our ears work and how they can be repaired.
  • 22.
  • 23.
  • 24. Rabbit(Oryctolagus cuniculus) ➜Rabbits are also used in experiments to study cardiovascular disease, skin conditions, and spinal cord injuries. ➜The surgically mutilated animals were observed for 24 weeks and then killed.
  • 25.
  • 27. Zoho Show To create beautiful presentations, download Zoho Show from Play Store https://zoho.to/cy7 species and strains of animals.pdf (This PDF has been generated using Zoho Show)