Smoking Robs Your Health and Your Wallet
Tobacco use is a threat to any person, regardless of gender, age, and race, cultural or educational background that causes over 18 types of cancer, and accounts for over 20% of cancer deaths worldwide. CANSA advocates stopping the use of any and all tobacco products.
Tobacco can be found in many forms, and all tobacco use is harmful. “People only think of cigarette smoking when you talk about tobacco, but it goes beyond that. They need to be aware that hubbly bubbly and e-cigarettes are just as harmful to your health and the health of those around you. It’s not just the smoker who has increased risk of disease, but also people exposed to second-hand smoke,” says CANSA Health Specialist, Prof Michael Herbst.
Tobacco Products Expensive
On top of the health implications, tobacco products are getting more expensive and are creating a huge negative impact on the economy.
Learn more: http://www.cansa.org.za/avoid-tobacco/
Tobacco use is the single most preventable cause of disease including many cancers and non-communicable diseases, so why not make every day a World No Tobacco Day with the CANSA’S eKick Butt Programme – a unique online smoking cessation programme.
Tobacco contains nicotine, a powerful and highly addictive substance, and most tobacco products deliver nicotine to the brain very effectively, bringing on the rapid onset and maintenance of addiction. This addiction leads to the unfortunate situation where an otherwise motivated, knowledgeable person, who understands the risks of tobacco, continues to use it.
http://www.cansa.org.za/avoid-tobacco/
Take A Deep Breath, for Health’s Sake!
Afrikaanse Media Vrystelling
View Infographics
26 April 2019 – Tobacco smoking is the main cause for unhealthy lungs, lung cancer, and over 20 other types of cancer. CANSA urges the public to consider quitting the use of tobacco in any form, to help lower cancer risk, as part of its 365 Day Health Challenge, and leading up to #WorldNoTobaccoDay (31 May).
Read more: https://www.cansa.org.za/take-a-deep-breath-for-healths-sake/
During June, the Cancer Association of South Africa (CANSA) reinforces the message of its 365 Day Health Campaign, that individuals have the power to lower cancer risk by making healthy lifestyle choices. Most people are not aware that drinking any type of alcohol (even in small amounts) increases the cancer risk. CANSA highlights the toll that alcohol takes on bodies and how it affects those around them.
www.cansa.org.za
CANSA supports the call from the Secretariat of the World Health Organization (WHO) Framework Convention on Tobacco Control that requires tobacco products to have plain packaging and graphic warning signs.
Plain packaging is an important reduction measure, making tobacco products less attractive, restricting the use of tobacco packaging to be used as a form of advertising and limiting misleading packaging and labelling. And the use of graphic (pictorial) package warnings will show the serious harmful effects of tobacco use.
Plain packaging restricts the use of logos, colours, brand images and promotional information. Other countries that have implemented plain packaging are UK, Northern Ireland and France who all passed laws to implement plain packaging as from May 2016. Tobacco consumption in Australia decreased by 13% during the three years since plain packaging was introduced.
Read more: http://www.cansa.org.za/plain-packaging-of-tobacco-products/
Youth Targeted by Tobacco Industry
On World No Tobacco Day, 31 May 2014, CANSA places the focus on tobacco use amongst the youth. Young adulthood is the period when our youth are most susceptible and vulnerable to commence smoking and they are thus a main target for the tobacco industry. We need to protect our youth from the harmful effects of tobacco and the industry’s manipulation to make them nicotine addicts.
http://www.cansa.org.za/avoid-tobacco/
In South Africa, we’re concerned about the burden of tobacco and especially about the tactics adopted by the tobacco industry to target youth. Research shows tobacco use is often initiated and established during adolescence and young adulthood.”
Smoking remains a major preventable cause of disease and premature death globally. Read more http://www.cansa.org.za/avoid-tobacco/
Tobacco use is the single most preventable cause of disease including many cancers and non-communicable diseases, so why not make every day a World No Tobacco Day with the CANSA’S eKick Butt Programme – a unique online smoking cessation programme.
Tobacco contains nicotine, a powerful and highly addictive substance, and most tobacco products deliver nicotine to the brain very effectively, bringing on the rapid onset and maintenance of addiction. This addiction leads to the unfortunate situation where an otherwise motivated, knowledgeable person, who understands the risks of tobacco, continues to use it.
http://www.cansa.org.za/avoid-tobacco/
Take A Deep Breath, for Health’s Sake!
Afrikaanse Media Vrystelling
View Infographics
26 April 2019 – Tobacco smoking is the main cause for unhealthy lungs, lung cancer, and over 20 other types of cancer. CANSA urges the public to consider quitting the use of tobacco in any form, to help lower cancer risk, as part of its 365 Day Health Challenge, and leading up to #WorldNoTobaccoDay (31 May).
Read more: https://www.cansa.org.za/take-a-deep-breath-for-healths-sake/
During June, the Cancer Association of South Africa (CANSA) reinforces the message of its 365 Day Health Campaign, that individuals have the power to lower cancer risk by making healthy lifestyle choices. Most people are not aware that drinking any type of alcohol (even in small amounts) increases the cancer risk. CANSA highlights the toll that alcohol takes on bodies and how it affects those around them.
www.cansa.org.za
CANSA supports the call from the Secretariat of the World Health Organization (WHO) Framework Convention on Tobacco Control that requires tobacco products to have plain packaging and graphic warning signs.
Plain packaging is an important reduction measure, making tobacco products less attractive, restricting the use of tobacco packaging to be used as a form of advertising and limiting misleading packaging and labelling. And the use of graphic (pictorial) package warnings will show the serious harmful effects of tobacco use.
Plain packaging restricts the use of logos, colours, brand images and promotional information. Other countries that have implemented plain packaging are UK, Northern Ireland and France who all passed laws to implement plain packaging as from May 2016. Tobacco consumption in Australia decreased by 13% during the three years since plain packaging was introduced.
Read more: http://www.cansa.org.za/plain-packaging-of-tobacco-products/
Youth Targeted by Tobacco Industry
On World No Tobacco Day, 31 May 2014, CANSA places the focus on tobacco use amongst the youth. Young adulthood is the period when our youth are most susceptible and vulnerable to commence smoking and they are thus a main target for the tobacco industry. We need to protect our youth from the harmful effects of tobacco and the industry’s manipulation to make them nicotine addicts.
http://www.cansa.org.za/avoid-tobacco/
In South Africa, we’re concerned about the burden of tobacco and especially about the tactics adopted by the tobacco industry to target youth. Research shows tobacco use is often initiated and established during adolescence and young adulthood.”
Smoking remains a major preventable cause of disease and premature death globally. Read more http://www.cansa.org.za/avoid-tobacco/
The theme for World No Tobacco Day for 2023 is “We Need Food Not Tobacco”. The Cancer Association of South Africa (CANSA) wholeheartedly supports the World Health Organisation (WHO) campaign to create awareness around the negative consequences of tobacco farming and use of tobacco.
CANSA aligns itself to the theme, ‘Tobacco – Threat to our Environment’ for World No Tobacco Day (31 May 2022). Together with the National Council Against Smoking (NCAS), Heart and Stroke Foundation of South Africa and the South African Medical Research Council, it continues campaigning for the new Control of Tobacco Products and Electronic Delivery Systems Bill to be passed by Parliament, to make it easier for South Africans to choose smoke-free lives and put an end to the threat tobacco-use poses to the environment.
Read more:
https://cansa.org.za/cansa-says-choose-smoke-free-lives/
When quitting smoking many people feel the need
for help in the form of a tobacco substitute. There are a wide variety of
different products billed as alternatives to smoking that are supposedly healthier.
The main additive in cigarettes that makes them so addictive is
nicotine. Hence most of the products that aim to replace smoking are nicotine
replacements such as nicotine gum, inhalers, patches and medications.
Other products are sold as smokeless tobacco such as snuff and hookah or as better because they are low yield cigarettes. Not all of these smoking substitutes are
healthy or even better than cigarettes.
International Cancer Survivors Day is celebrated during June, placing the spotlight not only on cancer survivors, but also their caregivers.
CANSA has compiled a list of tips and guidelines of support:
https://cansa.org.za/who-cares-for-cancer-patients-caregivers/
Helping Children with Cancer Feel Understood
CANSA partnered with the Hollard Insurance Group to release stories in short booklet form, to encourage children fighting cancer.
Read more:
https://cansa.org.za/helping-children-with-cancer-feel-understood/
More Related Content
Similar to Smoking Robs Your Health and Your Wallet (CANSA)
The theme for World No Tobacco Day for 2023 is “We Need Food Not Tobacco”. The Cancer Association of South Africa (CANSA) wholeheartedly supports the World Health Organisation (WHO) campaign to create awareness around the negative consequences of tobacco farming and use of tobacco.
CANSA aligns itself to the theme, ‘Tobacco – Threat to our Environment’ for World No Tobacco Day (31 May 2022). Together with the National Council Against Smoking (NCAS), Heart and Stroke Foundation of South Africa and the South African Medical Research Council, it continues campaigning for the new Control of Tobacco Products and Electronic Delivery Systems Bill to be passed by Parliament, to make it easier for South Africans to choose smoke-free lives and put an end to the threat tobacco-use poses to the environment.
Read more:
https://cansa.org.za/cansa-says-choose-smoke-free-lives/
When quitting smoking many people feel the need
for help in the form of a tobacco substitute. There are a wide variety of
different products billed as alternatives to smoking that are supposedly healthier.
The main additive in cigarettes that makes them so addictive is
nicotine. Hence most of the products that aim to replace smoking are nicotine
replacements such as nicotine gum, inhalers, patches and medications.
Other products are sold as smokeless tobacco such as snuff and hookah or as better because they are low yield cigarettes. Not all of these smoking substitutes are
healthy or even better than cigarettes.
International Cancer Survivors Day is celebrated during June, placing the spotlight not only on cancer survivors, but also their caregivers.
CANSA has compiled a list of tips and guidelines of support:
https://cansa.org.za/who-cares-for-cancer-patients-caregivers/
Helping Children with Cancer Feel Understood
CANSA partnered with the Hollard Insurance Group to release stories in short booklet form, to encourage children fighting cancer.
Read more:
https://cansa.org.za/helping-children-with-cancer-feel-understood/
'Feeling Sad' is a sensitively written book that explains a young boy's challenge after his mother dies from cancer, normalising his fears and helping him with ways to handle his grief. The book was written by Sally Anne Carter and illustrated by Alison Guy.
Borskanker affekteer baie Suid-Afrikaanse vroue en is die mees algemene kanker onder vroue in die land. Deur jou geesteswelstand te prioritiseer, kan die borskankerervaring meer hanteerbaar maak. KANSA verstaan dit, en bied beradingsdienste en ondersteuningsgroepe om kankeroorwinnaars en versorgers emosioneel te ondersteun.
Lees meer:
https://cansa.org.za/die-impak-van-borskanker-op-geestesgesondheid/
KANSA vier gedurende Augustus KANSA se ondersteuningsaanbiedinge. Ons lig die nuwe KANSA Inligtings- en Ondersteuningstoonbanke by sommige openbare hospitale uit wat deur personeel en opgeleide vrywilligers behartig word. KANSA het verder ’n reeks ‘Verwerking van Kanker’-plakkate ontwikkel wat beskikbaar is in Engels, Afrikaans, seSotho, seTswana, isiXhosa, isiZulu
https://cansa.org.za/ons-plaas-die-sorg-in-kansa-sorgmaand
CANSA celebrates CANSA Care Month in August to highlight its service offerings. We highlight our new CANSA Information and Support Desks at public hospitals, run by staff and trained volunteers. CANSA also developed a series of ‘Coping with Cancer’ posters in in English, Afrikaans, seSotho, seTswana, isiXhosa, isiZulu
https://cansa.org.za/putting-the-care-in-cansa-care-month
Die Kankervereniging van Suid-Afrika (KANSA) vestig die kollig op die impak van ’n kankerdiagnose op vroue, met betrekking tot vrugbaarheid. Wanneer hulle jonk is en die lewe gewoonlik pragtig en vol drome is, kan vroue wat met kanker gediagnoseer word, moeilike en onverwagse uitdagings in die gesig staar. Lees meer:
https://cansa.org.za/bewaar-hoop-gesprekke-met-vroue-kankerpasiente-oor-vrugbaarheid/
Preserving Hope: Fertility Discussions for Female Cancer Patients
CANSA highlights the impact of a cancer diagnosis on women, regarding fertility. At the peak of their youth, when life is usually a beautiful journey of dreams and possibilities, women diagnosed with cancer might meet difficult and unforeseen intersection of challenges. Find out more:
https://cansa.org.za/preserving-hope-fertility-discussions-for-female-cancer-patients/
On 4 March 2022, International Human Papilloma Virus (HPV) Day, the Cancer Association of South Africa (CANSA) supports the International Papillomavirus Society’s (IPVS) #OneLessWorry campaign, that aims to raise awareness of the virus, and the tools to overcome it, such as screening and vaccination programmes. HPV can cause cancer and is responsible for almost half a million deaths globally each year.
#OneLessWorry #HPV #EliminateCervicalCancer #CANSACervicalCancerAwareness
Find out more:
https://cansa.org.za/cervical-cancer/
Die Kankervereniging van Suid-Afrika (KANSA) ondersteun die tema ‘Tabak – ‘n Bedreiging vir ons Omgewing’ vir Wêreld Geen-Tabak Dag (31 Mei 2022). In samewerking met die Nasionale Raad Teen Rook (the National Council Against Smoking), die Hart en Beroerte-Stigting van Suid-Afrika en die Suid-Afrikaanse Mediese Navorsingsraad, help KANSA om die nuwe Wetsontwerp op Tabakprodukte en Elektrioniese Afleweringstelsels te bevorder sodat Suid-Afrikaners die keuse het vir ‘n rookvrye lewenswyse en om ‘n einde te bring aan die bedreiging wat die gebruik van tabakprodukte vir die omgewing inhou.
https://cansa.org.za/kansa-se-kies-rookvrye-lewenswyses/
KANSA raai mense aan om ’n aktiewe, gebalanseerde leefstyl te lei en sê dat sekere leefstylveranderinge kankerrisiko kan verlaag.* Verder beveel ons aan dat mense sekere leefstylfaktore uitsny wat hulle in gevaar stel vir kanker, veral kolorektale kanker wat een van die top drie kankers** onder mans en vroue in Suid-Afrika is. Slegte leefstylkeuses kan ’n belangrike rol speel wanneer dit by verhoogte risiko vir hierdie tipe kanker kom.
#CANSAColorectalCancer #ColorectalCancerAwareness #ActiveBalancedLifestyle
Lees meer:
https://cansa.org.za/is-jou-kolon-gesond/
CANSA promotes living an active balanced lifestyle and promotes that certain lifestyle changes can lower the risk of cancer.* It further advocates cutting out lifestyle factors that can put one at risk for cancer, especially colorectal cancer which is among the top three cancers** among men and women in South Africa. Poor lifestyle choices can play a significant part, in increasing risk for this type of cancer.
#CANSAColorectalCancer #ColorectalCancerAwareness #ActiveBalancedLifestyle
Read more:
Prostaatkanker is die mees algemene kanker onder mans wêreldwyd en die nommer een kanker wat Suid-Afrikaanse mans affekteer (Nasionale Kankerregister 2017), met 1 uit 17 mans wat die risiko loop om in hul leeftyd hiermee gediagnoseer te word. Lees meer:
https://cansa.org.za/mans-takel-saam-prostaatkanker/
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...
Smoking Robs Your Health and Your Wallet (CANSA)
1.
2. • Tobacco use costs national economies
enormously through increased health-
care costs and decreased productivity
• It worsens health inequalities and
exacerbates poverty, as the poorest
people spend less on essentials such as
food, education and health care
3. Dr Oleg Chestnov,
WHO’s Assistant Director-General for
Non-communicable Diseases (NCDs)
and Mental Health
4. • A pack of cigarettes cost an average
of R30
• Giving up smoking one pack a day,
will free up close to R1 000 a month,
which can be used in better ways
than harming your health, and the
health of those around you
5. • Living a Balanced Lifestyle encourages you to eat healthy, do regular exercise,
be stress free, go for regular screening, and avoid tobacco and alcohol
• By giving up smoking, you could rather spend your money on living healthier:
1 Day – R30
=
Buy a healthy
snack such as a
smoothie, pack
of apples,
bananas or
similar
1 Week – R210
=
Go for regular
screening, such
as a Pap smear*
or PSA** at your
nearest CANSA
Care Centre
Based on R30 per pack of cigarettes, and one pack per day
1 Month – R900
=
Spend time with
loved ones and
enjoy a healthy
meal out
1 Year – R11 000
=
Take that well-
deserved holiday
which you could
never afford or pay
that long-overdue
debt (such as
school fees)
*Pap smear – screening test for early diagnosis of cervical cancer
**PSA: Prostate Specific Antigen test – finger prick test to help detect prostate abnormalities
6. • About 6 million people die from tobacco use
every year, a figure that is predicted to grow
to more than 8 million a year by 2030,
accounting for over 20% of cancer deaths
worldwide
• 600 000 non-smokers are killed every year
by being exposed to second-hand smoke
• Smoking causes over 18 types of cancer:
cancers of the lung, bladder, renal pelvis,
oral cavity, oropharynx, hypopharynx,
oesophagus, larynx, pancreas, nasopharynx,
nasal cavity and sinuses, stomach, kidney,
ureter, uterine cervix, myeloid leukaemia,
colorectum, and ovary
7. Cigarettes are not the only dangerous
form of smoking.
Hubbly bubbly, e-cigarettes and
smokeless tobacco (such as snuff,
chewing-tobacco and ‘snus’) is also
harmful to your body
8. Tobacco and second-hand smoke contain over 1 400 dangerous and harmful
chemicals and 81 cancer causing chemicals have so far been identified in
cigarettes [according to the International Agency for Research on Cancer (IARC)].
Some of these are:
• Acetone – paint stripper
• Ammonia – toilet cleaner
• Arsenic – rat poison
• Butane – lighter fluid
• Carbon monoxide – exhaust fumes
• Naphthalene – mothballs
• Phenol – disinfectant
9. • Electronic cigarettes may contain nicotine.
When you inhale from an e-cigarette, an
atomizer turns liquid nicotine into a vapour
that can be puffed
• Traces of toxic chemicals, including known
carcinogens (cancer causing chemicals) have
been found in e-cigarettes
• Until more is known about the potential risks
of
e-cigarettes, the safe way is to say ‘no’ to
electronic cigarettes
10. Waterpipe smoke contains over 300 dangerous and harmful chemicals,
and 27 cancer causing chemicals have so far been identified in hookah.
Some of these are:
• Arsenic
• Carbon monoxide
• Formaldehyde
• Lead
• Nicotine
• Tar
11. Second-hand smoke is harmful
• Second-hand smoke contains twice as much tar and nicotine per
unit volume as does smoke inhaled from a cigarette.
• Has 3x as much cancer-causing benzopyrene,
• 5x as much carbon monoxide,
• and 50x as much ammonia.
• Second-hand smoke from pipes and cigars is equally as harmful.
• Causes lung cancer and contributes to the development of heart
disease
12. Besides the financial implications, quitting
tobacco can have a positive affect on your
health and lifestyle:
• Reducing the cancer risk
• Lower heart rate and blood pressure
• Breathing better
• Being able to walk without shortness
of breath
• Living a longer and healthier life
• Having more physical energy
• Being a good role model for children
and youth
13. CANSA’s eKick Butt Programme is an unique online
smoking cessation programme. Through a series of
emails, surveys and downloads, it guides you and
mentors quitting smoking and non-smoking becomes
a lifelong habit, not merely the time interval
between two cigarettes. This programme supplies a
series of handy tools – tried and tested – to help one
quit for good. www.ekickbutt.org.za
CANSA also endorses the ‘Allen Carr’s Easyway to Stop Smoking’
method. With a success rate of over 90% worldwide, Allen Carr’s
Easyway is the world’s most successful stop smoking programme with
150 Easyway clinics in over 40 countries worldwide. More info on
http://www.allencarr.co.za/
14. You have the right to a smoke-free world:
• Legislation is very clear about where people
may smoke and where smoking is prohibited
• It’s your right to complain when someone smokes
in your presence
• It’s also your right to take remedial steps if someone
smokes in any area where smoking is prohibited
• Adults may not smoke in a car when a passenger
under 12 years is present
• Smoking is not allowed in premises (including
private homes) used for commercial childcare
activities, such as crèches, or for schooling or tutoring
• No person under 18 may be allowed into a designated
smoking area
15. You have the right to a smoke-free world:
• No smoking in partially enclosed public places such as balconies, covered
patios, verandas, walkways, parking areas, etc.
• The fine for the owner of a restaurant, pub, bar and workplace that breaks
the smoking law is a maximum of R50 000 and for the individual smoker
R500
• The tobacco industry can no longer use ‘viral’ marketing like parties to target
young people
• The sale of tobacco products to and by persons under the age of 18 years is
prohibited
• Cigarette vending machines that sell tobacco products cannot be used to sell
other products like crisps, chocolates etc.
• Read the key points to this law here:
http://www.cansa.org.za/know-the-law-its-your-right-to-a-smoke-free-world/
16. Whilst the Cancer Association of South Africa (CANSA) has taken every precaution in compiling this presentation,
neither it, nor any contributor(s) to this presentation can be held responsible for any action (or the lack thereof) taken
by any person or organisation wherever they shall be based, as a result, direct or otherwise, of information contained
in, or accessed through, this presentation.
Thank You
www.cansa.org.za
Toll-free 0800 22 66 22