Až 2,5 milionů eur pro váš byznys. Právě to můžete získat díky evropskému dotačnímu programu SME Instrument. Do této chvíle s žádostí uspělo pouze 5 českých firem, 2 z nich díky JICu. Zjistěte, jak zvýšit své šance, poučte se z úspěšných žádostí a zeptejte se na vše, co vás o SME Instrument zajímá.

1. JIC Open Day, 18 May 2016, Brno
Our successful run through the
Phase 1 of the SME Instrument
Veronika Štěpánková
Enantis | Brno, Czech Republic | www.enantis.com
Project FGFSTAB

2. Outline
1. Enantis
2. FGFSTAB project
3. Project preparation
4. Project administration
5. Project reporting
6. Current status

3. About Enantis
• founded 2006
• biotechnology spin-off of Masaryk University
• close cooperation with academia
• micro/small enterprise
• enzymatic processes for biocatalysis,
bioremediation and biosensing
• protein engineering for development of
useful and valuable proteins

4. • proprietary protein stabilization platform based on the
computational design of stabilizing mutations
• faster than traditional laboratory techniques
• universal and cost-effective approach
Engineering protein stability

5. Fibroblast growth factors
• family of proteins that are essential for embryonic development,
angiogenesis, wound healing and as hormones that regulate
metabolism and cardiovascular system
• first published report in 1974
• more than 10,000 articles with ‘fibroblast growth factor’
in the Title

6. Industrial potential of FGFs
Stem cell research Medicine Cosmetics

7. Industrial potential of FGFs
Medicine CosmeticsStem cell research

8. Project FGFSTAB
• addresses industrial production of stable fibroblast growth
factors for broad therapeutic, research, and personal care
applications
• bridges the gap between Enantis knowledge and expertise on
protein engineering and the practical application of stable FGFs
(From Lab to Market)
• opens up significant business opportunity addressing the global
(EU) societal challenges

9. Project FGFSTAB
SME boosting biotechnology-based
industrial processes driving
competitiveness and sustainability

10. Preparing the application
1st trial

11. Preparing the application – 1st trial (06/2014)
• consultancy: JIC, external business expert
• time duration: 2 months (3 weeks intensively)
• main tasks and problems faced:
• include less science, more business
• identify target customers
• determine market size and market growth
• forecast sales
• make an eye-catchy document
• squeeze all information into 10 pages

12. Evaluation – 1st trial (06/2014)
• evaluation after less than two months after submission
• total score: 13.14 (impact 4.36, excellence 4.34, quality 4.44)
• above the quality threshold but not receiving funding
Certificate delivered by the EU Commission,
as the institution managing Horizon 2020,
the EU Framework Programme for Research
and Innovation 2014-2020

13. Preparing the application
2nd trial

14. Preparing the application - 2nd trial (10/2014)
• consultancy: JIC, two external business experts
• time duration: 1 months (2 weeks intensively)
• main tasks and problems faced:
• be as specific as possible
• add more numbers
• improve description of the company
• polish your text to make a professional impression

15. Evaluation – 2nd trial (10/2014)
• evaluation after less than two months after submission
• total score: 12.84 (impact 4.44, excellence 3.92, quality 4.48)
• slight improvement in impact and quality, decline of excellence
• below the quality threshold and not receiving funding

16. Preparing the application
3rd trial

17. Preparing the application – 3rd trial (12/2014)
• consultancy: none
• time duration: 2 days
• main problems faced:
• participant portal

18. Evaluation – 3rd trial (12/2014)
• evaluation after three months after submission
• total score: 13.57 (impact 4.45, excellence 4.50, quality 4.62)
• improvement in excellence
• above the quality threshold and receiving funding

19. FGFSTAB timeline
December 2014
March 2015
project submitted
evaluation report
April 2015 grant agreement
May 2015 start of the project
pre-financing payment
October 2015 end of the project
feasibility study submittedDecember 2015
payment of the balanceFebruary 2016

20. FGFSTAB administration
• cooperation with the Faculty of Economics at Masaryk
university and SME Instrument business coach
• market research (market segmentation, target customers)
• competitive analysis
• development of go-to-market strategy

21. FGFSTAB administration
• cooperation with the Faculty of Economics at Masaryk
university and SME Instrument business coach
• market research (market segmentation, target customers)
• competitive analysis
• development of go-to-market strategy
• validation of stable FGF in several accredited laboratories

22. FGFSTAB administration
• cooperation with the Faculty of Economics at Masaryk
university and SME Instrument business coach
• market research (market segmentation, target customers)
• competitive analysis
• development of go-to-market strategy
• validation of stable FGF in several accredited laboratories
• intellectual property – patent application submitted to EPO

23. FGFSTAB administration
• cooperation with the Faculty of Economics at Masaryk
university and SME Instrument business coach
• market research (market segmentation, target customers)
• competitive analysis
• development of go-to-market strategy
• validation of stable FGF in several accredited laboratories
• intellectual property – patent application submitted to EPO
• beginning of negotiations with potential distributors

24. Feasibility study (20 pages)

25. Questionnaire on socio-economic implications
• Did you benefit from coaching activities?
• Will you pursue the project idea?
• What source of finance do you intend to use to pursue the
project idea?
• What are your estimated forecasts (turnover, employees)?
• What are the main results of the grant?

26. Assessment of the FGFSTAB
• no useless documents requires
• only one deliverable – feasibility study
• fast evaluation proces
• SME Instrument phase 1 gave us:
 Better understanding of clients needs and knowledge about competitors
 Better knowledge about marketing methods
 Better understanding of technical issues
 Better understanding of IPR issues
 Increased reputation of the company

27. Assessment of the FGFSTAB
• no useless documents requires
• only one deliverable – feasibility study
• fast evaluation proces
• SME Instrument phase 1 gave us:
 Better understanding of clients needs and knowledge about competitors
 Better knowledge about marketing methods
 Better understanding of technical issues
 Better understanding of IPR issues
 Increased reputation of the company
Better chance to
succeed in SME
Instrument phase 2
(or other programme)

28. FGFSTAB now
• FGF2 STAB already introduced to the market
• signed distribution agreement with BioVendor a.s.
• pre-clinical safety assessment for cosmetic and healthcare markets
• continuous development of stable proteins with therapeutic
potential
• preparing proposal for SME Instrument phase 2

29. Enantis s.r.o
Kamenice 34
625 00 Brno, Czech Republic
+420 549 495 178
enantis@enantis.com
http://www.enantis.com/