The document outlines categories of drug information literature including primary, secondary, and tertiary sources. It discusses advantages and disadvantages of each category. Examples are provided of commonly used online drug information resources in the United States such as DailyMed, MedlinePlus, and clinical practice guidelines. The document encourages pharmacists to be proactive in identifying drug problems, using a systematic approach to answering drug information questions, and documenting their search methods.
Drug Information Services- DIC and Sources.raviapr7
Drug information services
Drug and Poison information Center, Sources of drug information
Computerized services, and the storage and retrieval of information.
Literature monitoring for pharmacovigilance – outsourcing or in house solutionJulio dos Anjos
• A brief introduction about relevance of literature screening for P V.
• Challenges of literature screening in general.
• Benefits and risks of completely outsourcing literature screening for PV.
• Business case elements that need to take into consideration when deciding on outsourcing or in-sourcing PV literature screening.
NCompass Live - July 5, 2017
http://nlc.nebraska.gov/ncompasslive/
They’re not the same? What’s the difference? How would I use them? If these are questions you have, join Annette Parde-Maass, from the National Network of Libraries of Medicine, as she gives a brief overview of these free databases from the National Library of Medicine, showcases some useful features, and takes your questions about these robust sites.
Presenter: Annette Parde-Maass, Community and Global Health Librarian, Creighton University Health Sciences Library, National Network of Libraries of Medicine MidContinental Region.
How to communicate scientific and medical information to patients, advocates ...jangeissler
How to communicate scientific and medical information to patients, advocates and caregivers, presented by Jan Geissler at the European Medical Writer's Symposium (EMWA) on 12 May 2016
Mobilizing informational resources for rare diseasesMaria Shkrob
Providing comprehensive disease-specific summaries remains a serious challenge as information is scattered across multiple resources. Elsevier is collaborating with a rare disease charity Findacure to create an informational portal for patients, researchers, and doctors to help finding new treatments, increase awareness, streamline information exchange and education. Using an integrative approach of automated and manual curation of literature, we constructed a knowledgebase containing an overview of the disease mechanisms, targets, drugs, key opinion leaders, and institutions. To demonstrate the utility of this approach, congenital hyperinsulinism will be discussed.
Development and validation of the Vi-Med ® tool for medication reviewHA VO THI
linical pharmacy practice in Vietnam is unregulated by standard procedures, thus motivating this study, which developed and validated a tool called Vi-Med ® for use in supporting medication review (MR) in Vietnamese hospitals. Six clinical pharmacists from six hospitals used the tool, which comprises three forms: Form 1 for the collection of patient information, Form 2 for the implementation of MR, and Form 3 for the documentation of pharmacist interventions (PIs). The tool also comes with eight pre-identified drug-related problems (DRPs) and seven PIs. The pharmacists were asked to categorize 30 PI-associated scenarios under appropriate DRPs and corresponding interventions. Concordance among the pharmacists was assessed on the basis of agreement level (%) and Cohen's kappa (κ). We also evaluated the user-friendliness of the tool using a four-point Likert scale. Concordance in the panel with respect to DRPs and PIs was substantial (κ = 0.76 and 80.4% agreement) and almost perfect (κ = 0.83 and 87.6% agreement), respectively. All the experts were satisfied with the structure and content of Vi-Med ®. Five of them evaluated the tool as very suitable, very useful, and definitely fitting for everyday use. Vi-Med ® satisfactorily achieved consistency and user-friendliness, enabling its use in daily clinical pharmacy practice.
Drug Information Services- DIC and Sources.raviapr7
Drug information services
Drug and Poison information Center, Sources of drug information
Computerized services, and the storage and retrieval of information.
Literature monitoring for pharmacovigilance – outsourcing or in house solutionJulio dos Anjos
• A brief introduction about relevance of literature screening for P V.
• Challenges of literature screening in general.
• Benefits and risks of completely outsourcing literature screening for PV.
• Business case elements that need to take into consideration when deciding on outsourcing or in-sourcing PV literature screening.
NCompass Live - July 5, 2017
http://nlc.nebraska.gov/ncompasslive/
They’re not the same? What’s the difference? How would I use them? If these are questions you have, join Annette Parde-Maass, from the National Network of Libraries of Medicine, as she gives a brief overview of these free databases from the National Library of Medicine, showcases some useful features, and takes your questions about these robust sites.
Presenter: Annette Parde-Maass, Community and Global Health Librarian, Creighton University Health Sciences Library, National Network of Libraries of Medicine MidContinental Region.
How to communicate scientific and medical information to patients, advocates ...jangeissler
How to communicate scientific and medical information to patients, advocates and caregivers, presented by Jan Geissler at the European Medical Writer's Symposium (EMWA) on 12 May 2016
Mobilizing informational resources for rare diseasesMaria Shkrob
Providing comprehensive disease-specific summaries remains a serious challenge as information is scattered across multiple resources. Elsevier is collaborating with a rare disease charity Findacure to create an informational portal for patients, researchers, and doctors to help finding new treatments, increase awareness, streamline information exchange and education. Using an integrative approach of automated and manual curation of literature, we constructed a knowledgebase containing an overview of the disease mechanisms, targets, drugs, key opinion leaders, and institutions. To demonstrate the utility of this approach, congenital hyperinsulinism will be discussed.
Development and validation of the Vi-Med ® tool for medication reviewHA VO THI
linical pharmacy practice in Vietnam is unregulated by standard procedures, thus motivating this study, which developed and validated a tool called Vi-Med ® for use in supporting medication review (MR) in Vietnamese hospitals. Six clinical pharmacists from six hospitals used the tool, which comprises three forms: Form 1 for the collection of patient information, Form 2 for the implementation of MR, and Form 3 for the documentation of pharmacist interventions (PIs). The tool also comes with eight pre-identified drug-related problems (DRPs) and seven PIs. The pharmacists were asked to categorize 30 PI-associated scenarios under appropriate DRPs and corresponding interventions. Concordance among the pharmacists was assessed on the basis of agreement level (%) and Cohen's kappa (κ). We also evaluated the user-friendliness of the tool using a four-point Likert scale. Concordance in the panel with respect to DRPs and PIs was substantial (κ = 0.76 and 80.4% agreement) and almost perfect (κ = 0.83 and 87.6% agreement), respectively. All the experts were satisfied with the structure and content of Vi-Med ®. Five of them evaluated the tool as very suitable, very useful, and definitely fitting for everyday use. Vi-Med ® satisfactorily achieved consistency and user-friendliness, enabling its use in daily clinical pharmacy practice.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
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1. 8/26/14
1
Agenda
• Icebreaker
• Drug
informa1on
references
– Categories
of
drug
informa1on
literature
• Advantages
vs.
Disadvantages
• Examples
– Some
commonly
used
resources
• Poten1al
topics
for
future
webinars
Icebreaker
• Presenters
– Võ
Thị
Hà,
MSPharm.
– Nguyễn
Như
Hồ,
MSPharm.
– Nguyễn
Đức
Như
Khuê,
PharmD/MPH
• ASendees
To
Wiki
or
Not
to
Wiki?
Categories
of
Drug
Informa6on
Literature
• Primary
literature
• Secondary
literature
• Ter1ary
literature
Primary
Literature
• Original
“research”
publica1ons.
• Source
of
informa1on
for
the
development
of
the
secondary
and
ter1ary
literature.
• Containing
a
detailed
descrip1on
of
study
design,
methodology,
and
results.
• Research
studies,
case
reports,
editorials,
disserta1ons,
leSers
to
the
editor,
and
randomized
control
trials
published
or
presented
for
the
first
1me.
• Top
1er
peer
reviewed
journals:
NEJM,
JAMA,
Archives
of
Internal
Medicine,
BMJ,
Pharmacotherapy,
Lancet,
etc…
Primary
Literature
(cont.)
• Advantages:
– Current,
original,
and
"cucng-‐edge"
informa1on.
– Pa#ent-‐oriented
&
evidence-‐based
medicine
that
can
be
directly
u#lized
to
help
care
for
pa#ents.
– Peer
reviewed,
unbiased
sugges1ons,
and
open
to
cri1ques
and
rebuSals.
• Disadvantages:
– Inaccurate
conclusions
d/t
flaws
in
methodology
– Improper
interpreta1on
d/t
lack
of
knowledge
about
scien1fic
methods
and
sta1s1cs
– Time
for
new
informa1on
to
be
widely
accepted
2. 8/26/14
2
Primary
Literature
in
Prac6ce
• Learn
to
be
cau1ous
with
new
informa1on.
• Is
the
ar1cle
from
a
peer-‐reviewed
journal?
• Understand
study
popula1on,
methods,
sta1s1cal
and
clinical
relevance
to
your
prac1ce
popula1on
before
extrapola1ng
to
your
pa1ent.
• Remember
case
reports
relate
only
to
one
pa1ent,
watch
for
bias,
and
avoid
relying
on
anecdotes.
Secondary
Literature
• Indexing
and
abstrac1ng
services.
• Examples:
– Medline
Database
covers
many
fields
of
medicine
including:
den1stry,
nursing,
veterinary,
pharmacy
and
hard
sciences.
• PubMed
Medline
• OVID
Medline
– Iowa
Drug
Informa6on
Service
indexes
English
(full
text)
ar1cles
relevant
to
drugs
and
treatment
of
disease
from
approximately
200
journals.
– Micromedex:
an
extensive
pharmacology
database
Secondary
Literature
(cont.)
• Advantages:
– Quick
access
to
the
primary
literature.
– Large
scope
of
and/or
concise
informa1on
on
specific
topics
– Generally
from
peer
reviewed
and
high
standard
journal
sources.
• Disadvantages:
– Lag
1me
– Availability
of
specific
journal
– Large
amount
of
informa1on
–
Search
techniques
– Cost
Ter6ary
Literature
• Textbooks
e.g.
Goodman
&
Gilman’s
Pharmacological
Basis
of
Therapeu1cs
• Compendia
(a
vast
array
of
informa1on
about
many
drugs)
e.g.
such
as
Facts
and
Comparisons
• Review
ar1cles
in
journals
that
thoroughly
summarize
a
par1cular
topic
can
also
be
considered
ter1ary
literature
(usually
more
up
to
date
than
text)
Ter6ary
Literature
(cont.)
• Advantages:
– Convenient
and
easy
to
use.
– Divided
into
specific
subjects,
e.g.
drug
interac1ons,
drugs
in
pregnancy.
– Informa1on
generally
well
accepted
• Disadvantages:
– Lag
1me
– Space
limita1on
– Less
thorough
review
– Possible
inappropriate
references
– Flawed
primary
literature
(poorly
done
studies)
Common
Online
Sources
(in
US)
• FDA
approved
drug
products:
www.accessdata.fda.gov/scripts/cder/drugsarda
• Dailymed
@
NLM
(database
of
product
package
inserts)
:
www.dailymed.nlm.nih.gov/dailymed
• Drug
informa1on
portal
@
NLM:
www.druginfo.nlm.nih.gov/drugportal
• Consumer
page
@
FDA:
www.fda.gov/forconsumers
• MedlinePlus
@
NIH:
www.nlm.nih.gov/medlineplus
• FDA
medica1on
guides:
www.fda.gov/drugs/drugsafety/
• MedWatch:
www.fda.gov/safety/medwatch
• Medica1on
safety:
www.ismp.org
• Drug
iden1fica1on:
pillbox.nlm.nih.gov
3. 8/26/14
3
Common
Online
Sources
(in
US)
• Diseases
&
Condi1ons
@
CDC:
www.cdc.gov/diseasescondi1ons
• Travel
medicine:
www.cdc.gov/travel
or
www.iamat.org
• Na1onal
guideline
clearinghouse:
www.guideline.gov
• Clinical
trials:
www.clinicaltrials.gov
• Na1onal
Cancer
Ins1tute:
www.cancer.gov
• Most
of
cancer
guidelines:
www.nccn.org
• DM
guideline:
ADA
2013
(less
commonly
used
AACE)
• HTN:
JNC
8
or
AHA
for
HTN
• An1thrombo1c
therapy:
CHEST
2012
• Dyslipidemia:
AHA/ACC
2013
Cholesterol
(aka
“ATP
4”)
• Be
proac1ve:
look
for
drug
problems.
No
other
healthcare
provider
has
the
unique
opportunity
to
improve
drug
therapy
that
pharmacists
have.
• Dig
deeper:
oxen
1mes
the
ques1on
that
is
originally
asked
is
not
the
ques1on
the
person
was
trying
to
ask.
• Be
skillful:
use
a
systema1c,
logical,
organized
approach.
• Keep
records:
document
your
search
methods
and
answer.
• There
may
be
more
than
one
correct
answer.
• An
acceptable
answer
may
be
“I
will
find
out”.
Drug
Informa1on
Pearls