Nurses who work night shifts are often sleep deprived, which can endanger their health and the health of others. Over half of nurses report being sleep deprived, which increases their risk of car accidents, medication errors, falling asleep on the job, and poor judgment. Long-term health risks of shift work include increased inflammatory markers, circadian rhythm disturbances, increased risk of various cancers, and atherosclerosis. Nurses should make sleep a priority, be aware of increased health risks from shift work, adopt a healthier lifestyle, and some nurses interviewed were willing to make lifestyle changes due to health concerns from shift work.