SlideShare a Scribd company logo
Sheet1Sleep with No S/MSleep withusing social media
Paticipants
185276376486.559768.5777.55.581079761086.51187128613761
4971565Mean7.86666666676.2333333333
ORIGINAL ARTICLE
Three-Dimensional Print of a Liver for
Preoperative Planning in Living
Donor Liver Transplantation
Nizar N. Zein,1 Ibrahim A. Hanouneh,1 Paul D. Bishop,2
Maggie Samaan,1 Bijan Eghtesad,3
Cristiano Quintini,3 Charles Miller,3 Lisa Yerian,4 and Ryan
Klatte5
1Department of Gastroenterology and Hepatology, Digestive
Disease Institute, 2Department of Vascular
Surgery, Heart and Vascular Institute, 3Department of Hepato-
Pancreato-Biliary and Transplant Surgery,
Digestive Disease Institute, 4Department of Anatomic
Pathology, Pathology and Laboratory Medicine
Institute, and 5Medical Device
Solution
s, Lerner Research Institute, Cleveland Clinic, Cleveland, OH
The growing demand for liver transplantation and the
concomitant scarcity of cadaveric livers have increased the need
for
living donor liver transplantation (LDLT). Ensuring the safety
of donors and recipients is critical. The preoperative identifica-
tion of the vascular and biliary tract anatomy with 3-
dimensional (3D) printing may allow better preoperative
surgical plan-
ning, avert unnecessary surgery in patients with potentially
unsuitable anatomy, and thereby decrease the complications of
liver transplant surgery. We developed a protocol and
successfully 3D-printed synthetic livers (along with their
complex net-
works of vascular and biliary structures) replicating the native
livers of 6 patients: 3 living donors and 3 respective recipients
who underwent LDLT. To our knowledge, these are the first
complete 3D-printed livers. Using standardized preoperative,
intraoperative, and postoperative assessments, we demonstrated
identical anatomical and geometrical landmarks in the
3D-printed models and native livers. Liver Transpl 19:1304-
1310, 2013. VC 2013 AASLD.
Received July 22, 2013; accepted July 26, 2013.
Three-dimensional (3D) printing is a process for mak-
ing a solid 3D object of virtually any shape from a dig-
ital model. A 3D printer works as an ordinary office
printer, but instead of placing a single layer of ink on
paper, the machine lays down successive thin layers
of a material to form a 3D object that replicates the
original one.1
The growing demand for liver transplantation and
the concomitant shortage of cadaveric livers have led
to a rise in living donor liver transplantation (LDLT),
in which resection of the right or left liver lobe is per-
formed for the purpose of liver transplantation.2 Liv-
ing donors are healthy individuals, so ensuring their
safety is of paramount importance. There have been a
number of reported donor deaths worldwide and a
substantial number of donor morbidities, so there is a
need for measures to optimize donor safety.3 Many of
these morbidities are attributable to incomplete pre-
operative anatomical characterization of vascular and
biliary structures and inaccurate estimates of the liver
volume; these data are needed to determine the extent
of the resection. This information provides a road
map, and its accuracy has improved with the intro-
duction of radiological software able to provide 3D
visualization of liver structures.4,5
3D imaging has the ability to better demonstrate the
3D relationships between vital vascular and biliary
structures and the surrounding parenchyma in com-
parison with conventional computed tomography (CT)
or magnetic resonance imaging (MRI). 3D imaging
Additional Supporting Information may be found in the online
version of this article.
Abbreviations: 2D, 2-dimensional; 3D, 3-dimensional; CT,
computed tomography; LDLT, living donor liver
transplantation; MRI,
magnetic resonance imaging; STL, stereolithography.
The study was supported by the Mikati Foundation Endowed
Chair in Liver Diseases (Nizar N. Zein).
Address reprint requests to Nizar N. Zein, M.D., Department of
Gastroenterology and Hepatology, Digestive Disease Institute,
Cleveland Clinic,
9500 Euclid Avenue, Mail Code A50, Cleveland, OH 44195.
Telephone: 1216-444-6126; FAX: 1216-445-5477; E-mail:
[email protected]
DOI 10.1002/lt.23729
View this article online at wileyonlinelibrary.com.
LIVER TRANSPLANTATION.DOI 10.1002/lt. Published on
behalf of the American Association for the Study of Liver
Diseases
LIVER TRANSPLANTATION 19:1304–1310, 2013
VC 2013 American Association for the Study of Liver Diseases.
renders volumes as well, and these are essential to
the surgical planning and execution process.6-8
Despite these advantages, 3D imaging has its short-
comings, including the reality that 3D images are
examined through a 2-dimensional (2D) computer
screen. Additionally, the intraoperative application of
preoperative 3D image findings is still difficult
because of the absence of reliable liver surface
markers corresponding to hepatic segmentation. Liver
deformity after mobilization during surgery has been
a major obstacle to the reliable use of preoperative 3D
imaging data; hence, intraoperative modalities such
as ultrasonography and cholangiography are often
used for the localization of vessels and major biliary
branches. Our attempt to produce a highly accurate
3D-printed model of a patient’s liver is intended to
overcome these obstacles and improve the safety of
LDLT. The accurate anatomical reproduction of the
donor liver represents progress in existing 3D imaging
technology and may enhance patient outcomes.
The aim of this novel study was to establish ana-
tomical precision and volumetric accuracy in 3D-
printed models for donors and recipients undergoing
LDLT.
PATIENTS AND METHODS
Patients
After receiving an approval from the Institutional
Review Board at the Cleveland Clinic, we prospectively
studied 3 consecutive patient pairs (3 donors and 3
recipients) who were evaluated and approved for
LDLT at the Cleveland Clinic between November 2012
and May 2013. The donors and the recipients under-
went standardized preoperative evaluations, which
included contrast-enhanced CT and MRI examina-
tions of the abdomen. These standardized images
were required for an analysis of morphological charac-
teristics and the vascular and biliary anatomy and for
an evaluation of the hepatic parenchyma. Addition-
ally, CT volumetric measurements of the entire donor
liver and both its lobes were taken with CT postpro-
cessing software (Medical Image Editor Thomas
Lange, B.S., Deutsches Herzzentrum, Berlin, Ger-
many). Using information from these imaging modal-
ities, we obtained comparative data for the donor and
recipient livers, including the volumes, lengths,
widths, and heights of the whole livers and their
lobes. Anatomical details, including the diameters of
the main portal vein, left hepatic vein, right hepatic
vein, and biliary tree, were also recorded. Demo-
graphic and clinical characteristics of the donors and
recipients at the time of surgery (age, sex, ethnicity,
weight, height, and body mass index) were also
recorded.
3D Printing
The overall process of 3D printing included 3D image
reconstruction, digital preparation, 3D printing, and
postprinting finishing work. Anatomical structures
(bile ducts, hepatic arteries, hepatic veins, and portal
veins) were digitally segmented with MeVis-supplied
(MeVis Medical

More Related Content

Similar to Sheet1Sleep with No SMSleep withusing social media Paticipants 18.docx

5.15.11.renal masses
5.15.11.renal masses5.15.11.renal masses
5.15.11.renal masses
Максим Зеленский
 
5.15.11.renal masses
5.15.11.renal masses5.15.11.renal masses
5.15.11.renal masses
Максим Зеленский
 
5.15.11.renal masses
5.15.11.renal masses5.15.11.renal masses
5.15.11.renal masses
Максим Зеленский
 
Cardiac Allograft Vasculopathy in Redo-Transplants- Is It More or Less (or) t...
Cardiac Allograft Vasculopathy in Redo-Transplants- Is It More or Less (or) t...Cardiac Allograft Vasculopathy in Redo-Transplants- Is It More or Less (or) t...
Cardiac Allograft Vasculopathy in Redo-Transplants- Is It More or Less (or) t...
Anya Ragnhildstveit
 
A_Rapid_Noninvasive_Assay_for_the_Detection_of 2013 96_17
A_Rapid_Noninvasive_Assay_for_the_Detection_of 2013 96_17A_Rapid_Noninvasive_Assay_for_the_Detection_of 2013 96_17
A_Rapid_Noninvasive_Assay_for_the_Detection_of 2013 96_17
Kevin Jaglinski
 
Stem Cell Therapy in Liver Cirrhosis
Stem Cell Therapy in Liver CirrhosisStem Cell Therapy in Liver Cirrhosis
Stem Cell Therapy in Liver Cirrhosis
dbpublications
 
Living Donor Liver Transplantation in Hepatocellular Carcinoma: How Far Can W...
Living Donor Liver Transplantation in Hepatocellular Carcinoma: How Far Can W...Living Donor Liver Transplantation in Hepatocellular Carcinoma: How Far Can W...
Living Donor Liver Transplantation in Hepatocellular Carcinoma: How Far Can W...
semualkaira
 
Volume overhydration in dialysis patients
Volume overhydration in dialysis patientsVolume overhydration in dialysis patients
Volume overhydration in dialysis patients
doremi78
 
recent advances in hepatobiliary and GI surgery
recent advances in hepatobiliary and GI surgeryrecent advances in hepatobiliary and GI surgery
recent advances in hepatobiliary and GI surgery
hr77
 
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic DilemmAbnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
pateldrona
 
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic DilemmAbnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
clinicsoncology
 
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic DilemmAbnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
AnonIshanvi
 
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic DilemmAbnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
SarkarRenon
 
Annals of Clinical and Medical Case Reports - Acmcasereport
Annals of Clinical and Medical Case Reports - AcmcasereportAnnals of Clinical and Medical Case Reports - Acmcasereport
Annals of Clinical and Medical Case Reports - Acmcasereport
semualkaira
 
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic DilemmAbnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
komalicarol
 

Similar to Sheet1Sleep with No SMSleep withusing social media Paticipants 18.docx (15)

5.15.11.renal masses
5.15.11.renal masses5.15.11.renal masses
5.15.11.renal masses
 
5.15.11.renal masses
5.15.11.renal masses5.15.11.renal masses
5.15.11.renal masses
 
5.15.11.renal masses
5.15.11.renal masses5.15.11.renal masses
5.15.11.renal masses
 
Cardiac Allograft Vasculopathy in Redo-Transplants- Is It More or Less (or) t...
Cardiac Allograft Vasculopathy in Redo-Transplants- Is It More or Less (or) t...Cardiac Allograft Vasculopathy in Redo-Transplants- Is It More or Less (or) t...
Cardiac Allograft Vasculopathy in Redo-Transplants- Is It More or Less (or) t...
 
A_Rapid_Noninvasive_Assay_for_the_Detection_of 2013 96_17
A_Rapid_Noninvasive_Assay_for_the_Detection_of 2013 96_17A_Rapid_Noninvasive_Assay_for_the_Detection_of 2013 96_17
A_Rapid_Noninvasive_Assay_for_the_Detection_of 2013 96_17
 
Stem Cell Therapy in Liver Cirrhosis
Stem Cell Therapy in Liver CirrhosisStem Cell Therapy in Liver Cirrhosis
Stem Cell Therapy in Liver Cirrhosis
 
Living Donor Liver Transplantation in Hepatocellular Carcinoma: How Far Can W...
Living Donor Liver Transplantation in Hepatocellular Carcinoma: How Far Can W...Living Donor Liver Transplantation in Hepatocellular Carcinoma: How Far Can W...
Living Donor Liver Transplantation in Hepatocellular Carcinoma: How Far Can W...
 
Volume overhydration in dialysis patients
Volume overhydration in dialysis patientsVolume overhydration in dialysis patients
Volume overhydration in dialysis patients
 
recent advances in hepatobiliary and GI surgery
recent advances in hepatobiliary and GI surgeryrecent advances in hepatobiliary and GI surgery
recent advances in hepatobiliary and GI surgery
 
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic DilemmAbnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
 
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic DilemmAbnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
 
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic DilemmAbnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
 
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic DilemmAbnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
 
Annals of Clinical and Medical Case Reports - Acmcasereport
Annals of Clinical and Medical Case Reports - AcmcasereportAnnals of Clinical and Medical Case Reports - Acmcasereport
Annals of Clinical and Medical Case Reports - Acmcasereport
 
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic DilemmAbnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
Abnormal Renal Mass in Adult Polycystic Kidney Disease: A Diagnostic Dilemm
 

More from bjohn46

Sheet1Rate your skills using the following scaleChapter 1 You Ma.docx
Sheet1Rate your skills using the following scaleChapter 1 You Ma.docxSheet1Rate your skills using the following scaleChapter 1 You Ma.docx
Sheet1Rate your skills using the following scaleChapter 1 You Ma.docx
bjohn46
 
Sheet1Quarter Sales PersonRegionQuarterly Sales31-MarSmithEast$750.docx
Sheet1Quarter Sales PersonRegionQuarterly Sales31-MarSmithEast$750.docxSheet1Quarter Sales PersonRegionQuarterly Sales31-MarSmithEast$750.docx
Sheet1Quarter Sales PersonRegionQuarterly Sales31-MarSmithEast$750.docx
bjohn46
 
Sheet1project codeproject nameEmployeesQB280001Account Management .docx
Sheet1project codeproject nameEmployeesQB280001Account Management .docxSheet1project codeproject nameEmployeesQB280001Account Management .docx
Sheet1project codeproject nameEmployeesQB280001Account Management .docx
bjohn46
 
Sheet1Quantity (miles of pipeline)Total CostTotal Fixed CostTotal .docx
Sheet1Quantity (miles of pipeline)Total CostTotal Fixed CostTotal .docxSheet1Quantity (miles of pipeline)Total CostTotal Fixed CostTotal .docx
Sheet1Quantity (miles of pipeline)Total CostTotal Fixed CostTotal .docx
bjohn46
 
Sheet1Pro Forma Income StatementYear 1Year 2Year 3Year 4Year 5Visi.docx
Sheet1Pro Forma Income StatementYear 1Year 2Year 3Year 4Year 5Visi.docxSheet1Pro Forma Income StatementYear 1Year 2Year 3Year 4Year 5Visi.docx
Sheet1Pro Forma Income StatementYear 1Year 2Year 3Year 4Year 5Visi.docx
bjohn46
 
Sheet1PMGT 576 Assignment Rubric – Unit 8 Assignment20Is the Lean .docx
Sheet1PMGT 576 Assignment Rubric – Unit 8 Assignment20Is the Lean .docxSheet1PMGT 576 Assignment Rubric – Unit 8 Assignment20Is the Lean .docx
Sheet1PMGT 576 Assignment Rubric – Unit 8 Assignment20Is the Lean .docx
bjohn46
 
Sheet1Presentation by Tony StudentSlide NumberSlide TitleSlide Tex.docx
Sheet1Presentation by Tony StudentSlide NumberSlide TitleSlide Tex.docxSheet1Presentation by Tony StudentSlide NumberSlide TitleSlide Tex.docx
Sheet1Presentation by Tony StudentSlide NumberSlide TitleSlide Tex.docx
bjohn46
 
Sheet1Pretax IncomeYang, Ziyun make sure to add back income t.docx
Sheet1Pretax IncomeYang, Ziyun make sure to add back income t.docxSheet1Pretax IncomeYang, Ziyun make sure to add back income t.docx
Sheet1Pretax IncomeYang, Ziyun make sure to add back income t.docx
bjohn46
 
Sheet1PMGT 576 Assignment Rubric – Unit 7 Assignment20Are all of t.docx
Sheet1PMGT 576 Assignment Rubric – Unit 7 Assignment20Are all of t.docxSheet1PMGT 576 Assignment Rubric – Unit 7 Assignment20Are all of t.docx
Sheet1PMGT 576 Assignment Rubric – Unit 7 Assignment20Are all of t.docx
bjohn46
 
Sheet1Plan APlan BPro Forma Income Statement AccountsEBIT700100013.docx
Sheet1Plan APlan BPro Forma Income Statement AccountsEBIT700100013.docxSheet1Plan APlan BPro Forma Income Statement AccountsEBIT700100013.docx
Sheet1Plan APlan BPro Forma Income Statement AccountsEBIT700100013.docx
bjohn46
 
Sheet1Phase of Business Financal Management needsDebt FinancingEq.docx
Sheet1Phase of Business Financal Management needsDebt FinancingEq.docxSheet1Phase of Business Financal Management needsDebt FinancingEq.docx
Sheet1Phase of Business Financal Management needsDebt FinancingEq.docx
bjohn46
 
Sheet1PeriodEngine Failures(a) 4-period moving average(b) weighted.docx
Sheet1PeriodEngine Failures(a) 4-period moving average(b) weighted.docxSheet1PeriodEngine Failures(a) 4-period moving average(b) weighted.docx
Sheet1PeriodEngine Failures(a) 4-period moving average(b) weighted.docx
bjohn46
 
Sheet1Participant#Verbal Label Condition (Smashed or Hit)Age Condi.docx
Sheet1Participant#Verbal Label Condition (Smashed or Hit)Age Condi.docxSheet1Participant#Verbal Label Condition (Smashed or Hit)Age Condi.docx
Sheet1Participant#Verbal Label Condition (Smashed or Hit)Age Condi.docx
bjohn46
 
Sheet1No.Strengths (3)Weaknesses (2)Recommendations (2)Evidence (u.docx
Sheet1No.Strengths (3)Weaknesses (2)Recommendations (2)Evidence (u.docxSheet1No.Strengths (3)Weaknesses (2)Recommendations (2)Evidence (u.docx
Sheet1No.Strengths (3)Weaknesses (2)Recommendations (2)Evidence (u.docx
bjohn46
 
Sheet1Moisture content analysis final resultsGroupValue of m3 (g)A.docx
Sheet1Moisture content analysis final resultsGroupValue of m3 (g)A.docxSheet1Moisture content analysis final resultsGroupValue of m3 (g)A.docx
Sheet1Moisture content analysis final resultsGroupValue of m3 (g)A.docx
bjohn46
 
Sheet1ManhattanBrooklynQueensThe BronxStaten IslandEducationMarita.docx
Sheet1ManhattanBrooklynQueensThe BronxStaten IslandEducationMarita.docxSheet1ManhattanBrooklynQueensThe BronxStaten IslandEducationMarita.docx
Sheet1ManhattanBrooklynQueensThe BronxStaten IslandEducationMarita.docx
bjohn46
 
Sheet1Learning Solultions NameVersion NumberMediumTypeLessonSc.docx
Sheet1Learning Solultions NameVersion NumberMediumTypeLessonSc.docxSheet1Learning Solultions NameVersion NumberMediumTypeLessonSc.docx
Sheet1Learning Solultions NameVersion NumberMediumTypeLessonSc.docx
bjohn46
 
Sheet1LMH10090H80M70L605040302010NumberRisk NameFull Risk CostRisk.docx
Sheet1LMH10090H80M70L605040302010NumberRisk NameFull Risk CostRisk.docxSheet1LMH10090H80M70L605040302010NumberRisk NameFull Risk CostRisk.docx
Sheet1LMH10090H80M70L605040302010NumberRisk NameFull Risk CostRisk.docx
bjohn46
 
Sheet1Item Price# of ItemsTotal PriceCups$1.896$11.34Plates$1.506$.docx
Sheet1Item Price# of ItemsTotal PriceCups$1.896$11.34Plates$1.506$.docxSheet1Item Price# of ItemsTotal PriceCups$1.896$11.34Plates$1.506$.docx
Sheet1Item Price# of ItemsTotal PriceCups$1.896$11.34Plates$1.506$.docx
bjohn46
 
Sheet1In_OutAustralian_CityInternational_CityAirlineRoutePort_Coun.docx
Sheet1In_OutAustralian_CityInternational_CityAirlineRoutePort_Coun.docxSheet1In_OutAustralian_CityInternational_CityAirlineRoutePort_Coun.docx
Sheet1In_OutAustralian_CityInternational_CityAirlineRoutePort_Coun.docx
bjohn46
 

More from bjohn46 (20)

Sheet1Rate your skills using the following scaleChapter 1 You Ma.docx
Sheet1Rate your skills using the following scaleChapter 1 You Ma.docxSheet1Rate your skills using the following scaleChapter 1 You Ma.docx
Sheet1Rate your skills using the following scaleChapter 1 You Ma.docx
 
Sheet1Quarter Sales PersonRegionQuarterly Sales31-MarSmithEast$750.docx
Sheet1Quarter Sales PersonRegionQuarterly Sales31-MarSmithEast$750.docxSheet1Quarter Sales PersonRegionQuarterly Sales31-MarSmithEast$750.docx
Sheet1Quarter Sales PersonRegionQuarterly Sales31-MarSmithEast$750.docx
 
Sheet1project codeproject nameEmployeesQB280001Account Management .docx
Sheet1project codeproject nameEmployeesQB280001Account Management .docxSheet1project codeproject nameEmployeesQB280001Account Management .docx
Sheet1project codeproject nameEmployeesQB280001Account Management .docx
 
Sheet1Quantity (miles of pipeline)Total CostTotal Fixed CostTotal .docx
Sheet1Quantity (miles of pipeline)Total CostTotal Fixed CostTotal .docxSheet1Quantity (miles of pipeline)Total CostTotal Fixed CostTotal .docx
Sheet1Quantity (miles of pipeline)Total CostTotal Fixed CostTotal .docx
 
Sheet1Pro Forma Income StatementYear 1Year 2Year 3Year 4Year 5Visi.docx
Sheet1Pro Forma Income StatementYear 1Year 2Year 3Year 4Year 5Visi.docxSheet1Pro Forma Income StatementYear 1Year 2Year 3Year 4Year 5Visi.docx
Sheet1Pro Forma Income StatementYear 1Year 2Year 3Year 4Year 5Visi.docx
 
Sheet1PMGT 576 Assignment Rubric – Unit 8 Assignment20Is the Lean .docx
Sheet1PMGT 576 Assignment Rubric – Unit 8 Assignment20Is the Lean .docxSheet1PMGT 576 Assignment Rubric – Unit 8 Assignment20Is the Lean .docx
Sheet1PMGT 576 Assignment Rubric – Unit 8 Assignment20Is the Lean .docx
 
Sheet1Presentation by Tony StudentSlide NumberSlide TitleSlide Tex.docx
Sheet1Presentation by Tony StudentSlide NumberSlide TitleSlide Tex.docxSheet1Presentation by Tony StudentSlide NumberSlide TitleSlide Tex.docx
Sheet1Presentation by Tony StudentSlide NumberSlide TitleSlide Tex.docx
 
Sheet1Pretax IncomeYang, Ziyun make sure to add back income t.docx
Sheet1Pretax IncomeYang, Ziyun make sure to add back income t.docxSheet1Pretax IncomeYang, Ziyun make sure to add back income t.docx
Sheet1Pretax IncomeYang, Ziyun make sure to add back income t.docx
 
Sheet1PMGT 576 Assignment Rubric – Unit 7 Assignment20Are all of t.docx
Sheet1PMGT 576 Assignment Rubric – Unit 7 Assignment20Are all of t.docxSheet1PMGT 576 Assignment Rubric – Unit 7 Assignment20Are all of t.docx
Sheet1PMGT 576 Assignment Rubric – Unit 7 Assignment20Are all of t.docx
 
Sheet1Plan APlan BPro Forma Income Statement AccountsEBIT700100013.docx
Sheet1Plan APlan BPro Forma Income Statement AccountsEBIT700100013.docxSheet1Plan APlan BPro Forma Income Statement AccountsEBIT700100013.docx
Sheet1Plan APlan BPro Forma Income Statement AccountsEBIT700100013.docx
 
Sheet1Phase of Business Financal Management needsDebt FinancingEq.docx
Sheet1Phase of Business Financal Management needsDebt FinancingEq.docxSheet1Phase of Business Financal Management needsDebt FinancingEq.docx
Sheet1Phase of Business Financal Management needsDebt FinancingEq.docx
 
Sheet1PeriodEngine Failures(a) 4-period moving average(b) weighted.docx
Sheet1PeriodEngine Failures(a) 4-period moving average(b) weighted.docxSheet1PeriodEngine Failures(a) 4-period moving average(b) weighted.docx
Sheet1PeriodEngine Failures(a) 4-period moving average(b) weighted.docx
 
Sheet1Participant#Verbal Label Condition (Smashed or Hit)Age Condi.docx
Sheet1Participant#Verbal Label Condition (Smashed or Hit)Age Condi.docxSheet1Participant#Verbal Label Condition (Smashed or Hit)Age Condi.docx
Sheet1Participant#Verbal Label Condition (Smashed or Hit)Age Condi.docx
 
Sheet1No.Strengths (3)Weaknesses (2)Recommendations (2)Evidence (u.docx
Sheet1No.Strengths (3)Weaknesses (2)Recommendations (2)Evidence (u.docxSheet1No.Strengths (3)Weaknesses (2)Recommendations (2)Evidence (u.docx
Sheet1No.Strengths (3)Weaknesses (2)Recommendations (2)Evidence (u.docx
 
Sheet1Moisture content analysis final resultsGroupValue of m3 (g)A.docx
Sheet1Moisture content analysis final resultsGroupValue of m3 (g)A.docxSheet1Moisture content analysis final resultsGroupValue of m3 (g)A.docx
Sheet1Moisture content analysis final resultsGroupValue of m3 (g)A.docx
 
Sheet1ManhattanBrooklynQueensThe BronxStaten IslandEducationMarita.docx
Sheet1ManhattanBrooklynQueensThe BronxStaten IslandEducationMarita.docxSheet1ManhattanBrooklynQueensThe BronxStaten IslandEducationMarita.docx
Sheet1ManhattanBrooklynQueensThe BronxStaten IslandEducationMarita.docx
 
Sheet1Learning Solultions NameVersion NumberMediumTypeLessonSc.docx
Sheet1Learning Solultions NameVersion NumberMediumTypeLessonSc.docxSheet1Learning Solultions NameVersion NumberMediumTypeLessonSc.docx
Sheet1Learning Solultions NameVersion NumberMediumTypeLessonSc.docx
 
Sheet1LMH10090H80M70L605040302010NumberRisk NameFull Risk CostRisk.docx
Sheet1LMH10090H80M70L605040302010NumberRisk NameFull Risk CostRisk.docxSheet1LMH10090H80M70L605040302010NumberRisk NameFull Risk CostRisk.docx
Sheet1LMH10090H80M70L605040302010NumberRisk NameFull Risk CostRisk.docx
 
Sheet1Item Price# of ItemsTotal PriceCups$1.896$11.34Plates$1.506$.docx
Sheet1Item Price# of ItemsTotal PriceCups$1.896$11.34Plates$1.506$.docxSheet1Item Price# of ItemsTotal PriceCups$1.896$11.34Plates$1.506$.docx
Sheet1Item Price# of ItemsTotal PriceCups$1.896$11.34Plates$1.506$.docx
 
Sheet1In_OutAustralian_CityInternational_CityAirlineRoutePort_Coun.docx
Sheet1In_OutAustralian_CityInternational_CityAirlineRoutePort_Coun.docxSheet1In_OutAustralian_CityInternational_CityAirlineRoutePort_Coun.docx
Sheet1In_OutAustralian_CityInternational_CityAirlineRoutePort_Coun.docx
 

Recently uploaded

How to Setup Warehouse & Location in Odoo 17 Inventory
How to Setup Warehouse & Location in Odoo 17 InventoryHow to Setup Warehouse & Location in Odoo 17 Inventory
How to Setup Warehouse & Location in Odoo 17 Inventory
Celine George
 
Walmart Business+ and Spark Good for Nonprofits.pdf
Walmart Business+ and Spark Good for Nonprofits.pdfWalmart Business+ and Spark Good for Nonprofits.pdf
Walmart Business+ and Spark Good for Nonprofits.pdf
TechSoup
 
Chapter wise All Notes of First year Basic Civil Engineering.pptx
Chapter wise All Notes of First year Basic Civil Engineering.pptxChapter wise All Notes of First year Basic Civil Engineering.pptx
Chapter wise All Notes of First year Basic Civil Engineering.pptx
Denish Jangid
 
คำศัพท์ คำพื้นฐานการอ่าน ภาษาอังกฤษ ระดับชั้น ม.1
คำศัพท์ คำพื้นฐานการอ่าน ภาษาอังกฤษ ระดับชั้น ม.1คำศัพท์ คำพื้นฐานการอ่าน ภาษาอังกฤษ ระดับชั้น ม.1
คำศัพท์ คำพื้นฐานการอ่าน ภาษาอังกฤษ ระดับชั้น ม.1
สมใจ จันสุกสี
 
BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...
BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...
BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...
Nguyen Thanh Tu Collection
 
NEWSPAPERS - QUESTION 1 - REVISION POWERPOINT.pptx
NEWSPAPERS - QUESTION 1 - REVISION POWERPOINT.pptxNEWSPAPERS - QUESTION 1 - REVISION POWERPOINT.pptx
NEWSPAPERS - QUESTION 1 - REVISION POWERPOINT.pptx
iammrhaywood
 
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...
PECB
 
How to Fix the Import Error in the Odoo 17
How to Fix the Import Error in the Odoo 17How to Fix the Import Error in the Odoo 17
How to Fix the Import Error in the Odoo 17
Celine George
 
MARY JANE WILSON, A “BOA MÃE” .
MARY JANE WILSON, A “BOA MÃE”           .MARY JANE WILSON, A “BOA MÃE”           .
MARY JANE WILSON, A “BOA MÃE” .
Colégio Santa Teresinha
 
Traditional Musical Instruments of Arunachal Pradesh and Uttar Pradesh - RAYH...
Traditional Musical Instruments of Arunachal Pradesh and Uttar Pradesh - RAYH...Traditional Musical Instruments of Arunachal Pradesh and Uttar Pradesh - RAYH...
Traditional Musical Instruments of Arunachal Pradesh and Uttar Pradesh - RAYH...
imrankhan141184
 
Your Skill Boost Masterclass: Strategies for Effective Upskilling
Your Skill Boost Masterclass: Strategies for Effective UpskillingYour Skill Boost Masterclass: Strategies for Effective Upskilling
Your Skill Boost Masterclass: Strategies for Effective Upskilling
Excellence Foundation for South Sudan
 
BÀI TẬP BỔ TRỢ TIẾNG ANH 8 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2023-2024 (CÓ FI...
BÀI TẬP BỔ TRỢ TIẾNG ANH 8 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2023-2024 (CÓ FI...BÀI TẬP BỔ TRỢ TIẾNG ANH 8 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2023-2024 (CÓ FI...
BÀI TẬP BỔ TRỢ TIẾNG ANH 8 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2023-2024 (CÓ FI...
Nguyen Thanh Tu Collection
 
Chapter 4 - Islamic Financial Institutions in Malaysia.pptx
Chapter 4 - Islamic Financial Institutions in Malaysia.pptxChapter 4 - Islamic Financial Institutions in Malaysia.pptx
Chapter 4 - Islamic Financial Institutions in Malaysia.pptx
Mohd Adib Abd Muin, Senior Lecturer at Universiti Utara Malaysia
 
A Independência da América Espanhola LAPBOOK.pdf
A Independência da América Espanhola LAPBOOK.pdfA Independência da América Espanhola LAPBOOK.pdf
A Independência da América Espanhola LAPBOOK.pdf
Jean Carlos Nunes Paixão
 
Hindi varnamala | hindi alphabet PPT.pdf
Hindi varnamala | hindi alphabet PPT.pdfHindi varnamala | hindi alphabet PPT.pdf
Hindi varnamala | hindi alphabet PPT.pdf
Dr. Mulla Adam Ali
 
Présentationvvvvvvvvvvvvvvvvvvvvvvvvvvvv2.pptx
Présentationvvvvvvvvvvvvvvvvvvvvvvvvvvvv2.pptxPrésentationvvvvvvvvvvvvvvvvvvvvvvvvvvvv2.pptx
Présentationvvvvvvvvvvvvvvvvvvvvvvvvvvvv2.pptx
siemaillard
 
writing about opinions about Australia the movie
writing about opinions about Australia the moviewriting about opinions about Australia the movie
writing about opinions about Australia the movie
Nicholas Montgomery
 
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
GeorgeMilliken2
 
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdfANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
Priyankaranawat4
 
Digital Artefact 1 - Tiny Home Environmental Design
Digital Artefact 1 - Tiny Home Environmental DesignDigital Artefact 1 - Tiny Home Environmental Design
Digital Artefact 1 - Tiny Home Environmental Design
amberjdewit93
 

Recently uploaded (20)

How to Setup Warehouse & Location in Odoo 17 Inventory
How to Setup Warehouse & Location in Odoo 17 InventoryHow to Setup Warehouse & Location in Odoo 17 Inventory
How to Setup Warehouse & Location in Odoo 17 Inventory
 
Walmart Business+ and Spark Good for Nonprofits.pdf
Walmart Business+ and Spark Good for Nonprofits.pdfWalmart Business+ and Spark Good for Nonprofits.pdf
Walmart Business+ and Spark Good for Nonprofits.pdf
 
Chapter wise All Notes of First year Basic Civil Engineering.pptx
Chapter wise All Notes of First year Basic Civil Engineering.pptxChapter wise All Notes of First year Basic Civil Engineering.pptx
Chapter wise All Notes of First year Basic Civil Engineering.pptx
 
คำศัพท์ คำพื้นฐานการอ่าน ภาษาอังกฤษ ระดับชั้น ม.1
คำศัพท์ คำพื้นฐานการอ่าน ภาษาอังกฤษ ระดับชั้น ม.1คำศัพท์ คำพื้นฐานการอ่าน ภาษาอังกฤษ ระดับชั้น ม.1
คำศัพท์ คำพื้นฐานการอ่าน ภาษาอังกฤษ ระดับชั้น ม.1
 
BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...
BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...
BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...
 
NEWSPAPERS - QUESTION 1 - REVISION POWERPOINT.pptx
NEWSPAPERS - QUESTION 1 - REVISION POWERPOINT.pptxNEWSPAPERS - QUESTION 1 - REVISION POWERPOINT.pptx
NEWSPAPERS - QUESTION 1 - REVISION POWERPOINT.pptx
 
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...
 
How to Fix the Import Error in the Odoo 17
How to Fix the Import Error in the Odoo 17How to Fix the Import Error in the Odoo 17
How to Fix the Import Error in the Odoo 17
 
MARY JANE WILSON, A “BOA MÃE” .
MARY JANE WILSON, A “BOA MÃE”           .MARY JANE WILSON, A “BOA MÃE”           .
MARY JANE WILSON, A “BOA MÃE” .
 
Traditional Musical Instruments of Arunachal Pradesh and Uttar Pradesh - RAYH...
Traditional Musical Instruments of Arunachal Pradesh and Uttar Pradesh - RAYH...Traditional Musical Instruments of Arunachal Pradesh and Uttar Pradesh - RAYH...
Traditional Musical Instruments of Arunachal Pradesh and Uttar Pradesh - RAYH...
 
Your Skill Boost Masterclass: Strategies for Effective Upskilling
Your Skill Boost Masterclass: Strategies for Effective UpskillingYour Skill Boost Masterclass: Strategies for Effective Upskilling
Your Skill Boost Masterclass: Strategies for Effective Upskilling
 
BÀI TẬP BỔ TRỢ TIẾNG ANH 8 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2023-2024 (CÓ FI...
BÀI TẬP BỔ TRỢ TIẾNG ANH 8 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2023-2024 (CÓ FI...BÀI TẬP BỔ TRỢ TIẾNG ANH 8 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2023-2024 (CÓ FI...
BÀI TẬP BỔ TRỢ TIẾNG ANH 8 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2023-2024 (CÓ FI...
 
Chapter 4 - Islamic Financial Institutions in Malaysia.pptx
Chapter 4 - Islamic Financial Institutions in Malaysia.pptxChapter 4 - Islamic Financial Institutions in Malaysia.pptx
Chapter 4 - Islamic Financial Institutions in Malaysia.pptx
 
A Independência da América Espanhola LAPBOOK.pdf
A Independência da América Espanhola LAPBOOK.pdfA Independência da América Espanhola LAPBOOK.pdf
A Independência da América Espanhola LAPBOOK.pdf
 
Hindi varnamala | hindi alphabet PPT.pdf
Hindi varnamala | hindi alphabet PPT.pdfHindi varnamala | hindi alphabet PPT.pdf
Hindi varnamala | hindi alphabet PPT.pdf
 
Présentationvvvvvvvvvvvvvvvvvvvvvvvvvvvv2.pptx
Présentationvvvvvvvvvvvvvvvvvvvvvvvvvvvv2.pptxPrésentationvvvvvvvvvvvvvvvvvvvvvvvvvvvv2.pptx
Présentationvvvvvvvvvvvvvvvvvvvvvvvvvvvv2.pptx
 
writing about opinions about Australia the movie
writing about opinions about Australia the moviewriting about opinions about Australia the movie
writing about opinions about Australia the movie
 
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
 
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdfANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
 
Digital Artefact 1 - Tiny Home Environmental Design
Digital Artefact 1 - Tiny Home Environmental DesignDigital Artefact 1 - Tiny Home Environmental Design
Digital Artefact 1 - Tiny Home Environmental Design
 

Sheet1Sleep with No SMSleep withusing social media Paticipants 18.docx

  • 1. Sheet1Sleep with No S/MSleep withusing social media Paticipants 185276376486.559768.5777.55.581079761086.51187128613761 4971565Mean7.86666666676.2333333333 ORIGINAL ARTICLE Three-Dimensional Print of a Liver for Preoperative Planning in Living Donor Liver Transplantation Nizar N. Zein,1 Ibrahim A. Hanouneh,1 Paul D. Bishop,2 Maggie Samaan,1 Bijan Eghtesad,3 Cristiano Quintini,3 Charles Miller,3 Lisa Yerian,4 and Ryan Klatte5 1Department of Gastroenterology and Hepatology, Digestive Disease Institute, 2Department of Vascular Surgery, Heart and Vascular Institute, 3Department of Hepato- Pancreato-Biliary and Transplant Surgery, Digestive Disease Institute, 4Department of Anatomic Pathology, Pathology and Laboratory Medicine Institute, and 5Medical Device Solution s, Lerner Research Institute, Cleveland Clinic, Cleveland, OH The growing demand for liver transplantation and the
  • 2. concomitant scarcity of cadaveric livers have increased the need for living donor liver transplantation (LDLT). Ensuring the safety of donors and recipients is critical. The preoperative identifica- tion of the vascular and biliary tract anatomy with 3- dimensional (3D) printing may allow better preoperative surgical plan- ning, avert unnecessary surgery in patients with potentially unsuitable anatomy, and thereby decrease the complications of liver transplant surgery. We developed a protocol and successfully 3D-printed synthetic livers (along with their complex net- works of vascular and biliary structures) replicating the native livers of 6 patients: 3 living donors and 3 respective recipients who underwent LDLT. To our knowledge, these are the first complete 3D-printed livers. Using standardized preoperative, intraoperative, and postoperative assessments, we demonstrated identical anatomical and geometrical landmarks in the 3D-printed models and native livers. Liver Transpl 19:1304- 1310, 2013. VC 2013 AASLD. Received July 22, 2013; accepted July 26, 2013. Three-dimensional (3D) printing is a process for mak- ing a solid 3D object of virtually any shape from a dig-
  • 3. ital model. A 3D printer works as an ordinary office printer, but instead of placing a single layer of ink on paper, the machine lays down successive thin layers of a material to form a 3D object that replicates the original one.1 The growing demand for liver transplantation and the concomitant shortage of cadaveric livers have led to a rise in living donor liver transplantation (LDLT), in which resection of the right or left liver lobe is per- formed for the purpose of liver transplantation.2 Liv- ing donors are healthy individuals, so ensuring their safety is of paramount importance. There have been a number of reported donor deaths worldwide and a substantial number of donor morbidities, so there is a need for measures to optimize donor safety.3 Many of these morbidities are attributable to incomplete pre- operative anatomical characterization of vascular and biliary structures and inaccurate estimates of the liver volume; these data are needed to determine the extent of the resection. This information provides a road map, and its accuracy has improved with the intro- duction of radiological software able to provide 3D visualization of liver structures.4,5
  • 4. 3D imaging has the ability to better demonstrate the 3D relationships between vital vascular and biliary structures and the surrounding parenchyma in com- parison with conventional computed tomography (CT) or magnetic resonance imaging (MRI). 3D imaging Additional Supporting Information may be found in the online version of this article. Abbreviations: 2D, 2-dimensional; 3D, 3-dimensional; CT, computed tomography; LDLT, living donor liver transplantation; MRI, magnetic resonance imaging; STL, stereolithography. The study was supported by the Mikati Foundation Endowed Chair in Liver Diseases (Nizar N. Zein). Address reprint requests to Nizar N. Zein, M.D., Department of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Avenue, Mail Code A50, Cleveland, OH 44195. Telephone: 1216-444-6126; FAX: 1216-445-5477; E-mail: [email protected] DOI 10.1002/lt.23729
  • 5. View this article online at wileyonlinelibrary.com. LIVER TRANSPLANTATION.DOI 10.1002/lt. Published on behalf of the American Association for the Study of Liver Diseases LIVER TRANSPLANTATION 19:1304–1310, 2013 VC 2013 American Association for the Study of Liver Diseases. renders volumes as well, and these are essential to the surgical planning and execution process.6-8 Despite these advantages, 3D imaging has its short- comings, including the reality that 3D images are examined through a 2-dimensional (2D) computer screen. Additionally, the intraoperative application of preoperative 3D image findings is still difficult because of the absence of reliable liver surface markers corresponding to hepatic segmentation. Liver deformity after mobilization during surgery has been a major obstacle to the reliable use of preoperative 3D imaging data; hence, intraoperative modalities such as ultrasonography and cholangiography are often
  • 6. used for the localization of vessels and major biliary branches. Our attempt to produce a highly accurate 3D-printed model of a patient’s liver is intended to overcome these obstacles and improve the safety of LDLT. The accurate anatomical reproduction of the donor liver represents progress in existing 3D imaging technology and may enhance patient outcomes. The aim of this novel study was to establish ana- tomical precision and volumetric accuracy in 3D- printed models for donors and recipients undergoing LDLT. PATIENTS AND METHODS Patients After receiving an approval from the Institutional Review Board at the Cleveland Clinic, we prospectively studied 3 consecutive patient pairs (3 donors and 3 recipients) who were evaluated and approved for LDLT at the Cleveland Clinic between November 2012 and May 2013. The donors and the recipients under- went standardized preoperative evaluations, which included contrast-enhanced CT and MRI examina-
  • 7. tions of the abdomen. These standardized images were required for an analysis of morphological charac- teristics and the vascular and biliary anatomy and for an evaluation of the hepatic parenchyma. Addition- ally, CT volumetric measurements of the entire donor liver and both its lobes were taken with CT postpro- cessing software (Medical Image Editor Thomas Lange, B.S., Deutsches Herzzentrum, Berlin, Ger- many). Using information from these imaging modal- ities, we obtained comparative data for the donor and recipient livers, including the volumes, lengths, widths, and heights of the whole livers and their lobes. Anatomical details, including the diameters of the main portal vein, left hepatic vein, right hepatic vein, and biliary tree, were also recorded. Demo- graphic and clinical characteristics of the donors and recipients at the time of surgery (age, sex, ethnicity, weight, height, and body mass index) were also recorded. 3D Printing The overall process of 3D printing included 3D image reconstruction, digital preparation, 3D printing, and postprinting finishing work. Anatomical structures
  • 8. (bile ducts, hepatic arteries, hepatic veins, and portal veins) were digitally segmented with MeVis-supplied (MeVis Medical