- Jesus is questioned about the most important commandment, and replies that the greatest is to love God with all your heart, soul, and mind. The second greatest commandment is to love your neighbor as yourself. All of God's law and prophets are based on these two commandments. - Loving others is a sign that we love God, as God loved us first. Anyone who says they love God but hates other Christians is a liar. We cannot love God whom we cannot see if we do not love others we can see.