The document outlines the schedule and topics for the 246th National Meeting of the American Chemical Society Division of Small Chemical Businesses held from September 8-12, 2013 in Indianapolis, Indiana. It includes oral presentations and poster sessions on various topics related to small chemical businesses over the course of the conference, including business development, entrepreneurship, technology commercialization, and networking opportunities for small businesses in the chemical industry.
This document provides information about RAIN (Readiness Acceleration and Innovation Network), a proposed biotechnology and health-based innovation center in Tacoma, Washington. RAIN would streamline support for new ideas and accelerate commercialization of products serving the military, medical, and industrial sectors. It would be located near the University of Washington Tacoma and local healthcare providers. The center aims to form companies, train workers, and create jobs through access to experts, data, and students. It outlines RAIN's leadership team, facilities operations team, funding sources, metrics for success, and impact on the local community and economy.
Through an open call, progressive organizations can fast-track R&D and traditional product development by reaching out to some of the world's most creative thinkers—icitizens who thrive on solving tough challenges and accelerating change.
Presentation Sustainability in Project Management, by Nick Lakenman. During IPMA Parade 2014, Nick showed his excellence and knowledge about sustainable results in Project Management.
Robert Kirschbaum (DSM) - The balancing act between radical and incremental i...Anis Bedda
Robert Kirschbaum (DSM)
Title: The balancing act between radical and incremental innovation (and the role of intrapreneurs)
Intrapreneurship Conference 2014
www.intrapreneurshipconference.com
#Intracnf14
Nina Kohnen, Covidien - Speaker at the marcus evans Medical Device Manufacturing Summit Fall 2012, held in Colorado Springs, delivered her presentation entitled Product Design and Innovation
Ricoh Academy Revisited bijeenkomst bij DSM met het thema Chaning Business Models & Innovation. Een gevarieerd programma met mooie sprekers. Sustainability & Alliances als rode draad door het programma.
2014 Medical Design Excellence Awards Ceremony BrochureJames Costigan
The document summarizes the 2014 MDEA Ceremony which will honor Dean Kamen with the Lifetime Achievement Award for his contributions to medical device innovation over his career. It provides details about Kamen and quotes from him encouraging further innovation. It also lists the finalists in various categories that will be recognized at the ceremony for exceptional medical device design, engineering, and innovation.
1) Firms increasingly link with scientific research to develop new products and gain a competitive advantage. However, basic research is difficult for companies to understand and apply commercially.
2) While science aims to further knowledge, companies seek immediate economic returns, leading to cultural differences between the two. Companies also fear sharing secrets.
3) By investing in understanding external scientific knowledge, firms can avoid costly experiments and access public research to transfer into business applications, providing benefits for both companies and society. However, basic research progresses slowly while markets demand quicker solutions.
This document provides information about RAIN (Readiness Acceleration and Innovation Network), a proposed biotechnology and health-based innovation center in Tacoma, Washington. RAIN would streamline support for new ideas and accelerate commercialization of products serving the military, medical, and industrial sectors. It would be located near the University of Washington Tacoma and local healthcare providers. The center aims to form companies, train workers, and create jobs through access to experts, data, and students. It outlines RAIN's leadership team, facilities operations team, funding sources, metrics for success, and impact on the local community and economy.
Through an open call, progressive organizations can fast-track R&D and traditional product development by reaching out to some of the world's most creative thinkers—icitizens who thrive on solving tough challenges and accelerating change.
Presentation Sustainability in Project Management, by Nick Lakenman. During IPMA Parade 2014, Nick showed his excellence and knowledge about sustainable results in Project Management.
Robert Kirschbaum (DSM) - The balancing act between radical and incremental i...Anis Bedda
Robert Kirschbaum (DSM)
Title: The balancing act between radical and incremental innovation (and the role of intrapreneurs)
Intrapreneurship Conference 2014
www.intrapreneurshipconference.com
#Intracnf14
Nina Kohnen, Covidien - Speaker at the marcus evans Medical Device Manufacturing Summit Fall 2012, held in Colorado Springs, delivered her presentation entitled Product Design and Innovation
Ricoh Academy Revisited bijeenkomst bij DSM met het thema Chaning Business Models & Innovation. Een gevarieerd programma met mooie sprekers. Sustainability & Alliances als rode draad door het programma.
2014 Medical Design Excellence Awards Ceremony BrochureJames Costigan
The document summarizes the 2014 MDEA Ceremony which will honor Dean Kamen with the Lifetime Achievement Award for his contributions to medical device innovation over his career. It provides details about Kamen and quotes from him encouraging further innovation. It also lists the finalists in various categories that will be recognized at the ceremony for exceptional medical device design, engineering, and innovation.
1) Firms increasingly link with scientific research to develop new products and gain a competitive advantage. However, basic research is difficult for companies to understand and apply commercially.
2) While science aims to further knowledge, companies seek immediate economic returns, leading to cultural differences between the two. Companies also fear sharing secrets.
3) By investing in understanding external scientific knowledge, firms can avoid costly experiments and access public research to transfer into business applications, providing benefits for both companies and society. However, basic research progresses slowly while markets demand quicker solutions.
Innovation is the application of new solutions to meet new requirements or needs. It differs from invention in that innovation refers to using ideas or methods, while invention refers to creating them. Innovation can occur in individuals, societies, businesses, and organizations through sources like changes in markets, demographics, or scientific knowledge. Common goals of innovation programs are improved quality, new markets, and reduced costs, though failures can occur from issues like poor goal definition, participation, or monitoring of results. Innovation is measured globally using indexes that rank countries based on factors like research and development spending and patent activity.
Hashaam Masood is applying for a position at the hiring company. He has over 5 years of experience as an entrepreneur, software engineer, and manager of industrial relations. He developed several software projects for healthcare, mobile apps, and web interfaces. Masood believes his passion, skills, and experiences would make him an asset to any organization. He is seeking an interview to further discuss the opportunity.
R&D To Commercialisation - LSX C-Suite Challenges in Life Sciences Survey 201...Covance
Learn key insights from biotech executives about their path from R&D to commercialisation in this whitepaper, part of the LSX C-Suite Challenges in Life Sciences Survey 2018 report.
This document provides an overview of marketing strategies for early-stage biotech startups. It discusses how early-stage marketing can assess market potential and address investor concerns. Key aspects of a marketing portfolio are outlined, including market research, branding, pitch decks, and gaining exposure. Early-stage marketing goals are highlighted as well as metrics that are important to investors like market opportunity, proven traction, team strengths, and unique value proposition. Resources for market research and positioning are also provided.
12.5.18 "How For-Profit Companies Can Be a Part of the Open Environment" pres...DuraSpace
"How For-Profit Companies Can Be a Part of the Open Environment"
DuraSpace Members Hot Topics webinar
Presented on 12.5.18
Presented by: Andrew Smeall of Hindawi, Brian Hole of Ubiquity Press and Anita Bandrowski of SciCrunch
The Arrowhead Center at New Mexico State University works to create an innovation-driven economy through research, business development, education and policy analysis. It conducts research to move ideas to market, supports startups and growing companies, and provides hands-on learning for students. The Center launches new ventures through programs like Launch and manages Arrowhead Park, a research and business park. It also analyzes economic and policy impacts and facilitates technology transfer from NMSU to the private sector.
Teaching Students To Write A Persuasive EssayRosa Williams
The document outlines the steps for seeking writing help from HelpWriting.net, which includes registering for an account, completing an order form with instructions and deadline, and reviewing writer bids before choosing one and placing a deposit to start the assignment. It notes that customers can request revisions until satisfied with the paper and are ensured original content or a full refund.
1. The document discusses challenges that financial institutions face when adopting external innovations from startups and vendors. It explores issues such as risk management, cultural differences, and long sales cycles.
2. It identifies "leaks" in the innovation process where collaboration is lacking between innovators and customers during problem identification and solution testing. It also finds issues with startups successfully adopting their solutions.
3. Potential solutions discussed include financial institutions being more open to startups they have existing relationships with, startups employing staff with customer knowledge, and partnering with companies that complement their solutions and have customer connections.
Analysis of drivers that cause restricted access to funding for smaller biotech companies.
A detailed reviewed of the steps
venture capitalists and companies are
taking — models such as fail-fast R&D, asset-centric funding and more.
Proposal of a model that
could radically change R&D by taking a
much more holistic approach to drug
development, sharing information to
learn in real time across the cycle of care
and fundamentally changing how risk
and reward are allocated.
“The Most Recommended Pharma & Life Sciences Solution providers in 2021” highlighting the pharmaceutical and healthcare industries help to improving the human health and forwarding life-expectancy one step further.
This document provides an agenda and overview for the fourth Innovation Louisiana conference being held November 14-15 at the BioInnovation Center in New Orleans. The conference will feature panels on topics relevant to life sciences entrepreneurs such as lessons from experienced biotech founders, intellectual property protection, venture capital, and developing partnerships. Keynote speakers will discuss determining the right market fit and research partnerships. The goal is to help attendees hone their business strategies, find funding, and make connections to further commercialize their innovations. A technology showcase and pitch competition are also planned.
Program from the Innovation Louisiana 2013 life sciences entrepreneurship conference, presented by the New Orleans BioInnovation Center. Featuring sessions on startup funding, legal issues for growth startups, technology transfer, and other issues affecting life sciences startups
The Innovation Commercialization Process:A Case StudyCheryl Tulkoff
When people think of innovation, they frequently think of the “big idea” or product while overlooking the fact that innovation is really a process.
They think of innovation solely in the creative sense rather than considering the importance or even existence of an innovation methodology.
Countless examples exist of good inventions that never succeeded in the marketplace or failed to live up to expectations while lesser ones thrived.
Many of these failures could have been eliminated through use of an innovation commercialization process.
This presentation describes the process and demonstrates its application through a case study.
Academia is the single largest untapped resource for addressing unmet global needs. In the age of the so called knowledge economy, they have the capacity and opportunity to drive global change. Question is............. as largely publicly funded, free to do as they please researchers, do they have the strategy and courage to implement change.
The document discusses achieving excellence in product development and launch. It provides context on the challenges facing the pharmaceutical, consumer goods, and retail industries in developing and launching new products given dynamic market conditions. It identifies key lessons that can help businesses, including focusing on critical success factors, embedding launch capabilities, navigating uncertainty, and getting launch fundamentals right. Digital technologies, customer insights, and adapting operating models are also discussed as important to maintaining speed to market and innovation. The document covers industry dynamics, digital technologies, and future operating models as they relate to product development and launch excellence.
Major pharmaceutical companies are reinventing their early-stage research and development through open innovation models. This includes establishing regional innovation hubs and centers that identify promising early-stage innovations and establish novel collaborations. For example, Johnson & Johnson, Merck, and Pfizer have set up innovation hubs in locations like Boston, London, and Shanghai. China in particular represents a large market and talent pool for innovation, with the government strongly supporting initiatives in areas like recruiting top talent and funding major new drug development projects. Johnson & Johnson and WuXi AppTec are collaborating through an accelerator program that pairs scientific assets and entrepreneurs to form new companies developing transformational products in China for the global market.
Innovation Management - A capsuled presentation on Innovation for studentsSuren Mathur
A crisp presentation on Innovation, its definitions, meaning and how to ' manage innovation' as a Manager / Executive within a business organization / company
In this issue, “The 20 Best Tech Companies to Work for in 2019” we’ve enlisted some such companies which have initiated an appreciable level of ethical standards in their organizations.
The article discusses how data and new technologies are enabling innovation like never before. It outlines several key points:
1) The amount of digital data from various sources is massively increasing, including data from IT systems, research databases, patent filings, and new sources like social media and the Internet of Things.
2) Collaboration platforms and crowd-sourcing tools can help organizations assess, prioritize, fund, and realize innovation opportunities by pulling insights from various participants.
3) A wide range of data sources must be harnessed for insights, including repositories, exchanges, unstructured data, social media, sensor data, and more. Both looking back longitudinally and forward visioning with rapid prototyping
Terahertz (T-ray) techniques for measuring, profiling, and mapping of semiconductor features and doping concentration of via a T-ray volume imaging route, deep-level spectroscopy, and empirical modeling; and application thereof for semiconductor doping concentration thickness profiling and surface mapping for both undoped and doped semiconductors.
This paper outlines the basic technology and economic model of the core silicon technology. Silicon is the second most abundant element on the earth’s crust but there is no specific deposit or mine for silicon.
The only source for silicon is “sand” that the earth has an abundant supply. Here we outline the basic steps of manufacturing silicon ingot and wafers. It is projected that, once produced, these products will gain immediate market access, thus creating economic activities in a reasonably short period of time. The three initial products that could stem from the basic silicon ingot are silicon wafers, for both semiconductor and solar cell applications, and optical fiber for communication. This report focuses on the essential silicon
technology to produce silicon ingot, and silicon wafer, as the first step. Finally, the historic data available for the silicon wafer consumption per year have been modeled with the well-known Bass diffusion model.
It was found that with modified parameters, the Bass model fits the historic data well and the same model allows a projection for a few years in the future. This projected economic activities, therefore, encourages a social transformation towards a technological self-sufficiency.
Keywords: Silicon technology; Bass diffusion model; Silicon wafer consumption; Social transformation;
Technological self-sufficiency
DOI: 10.31031/NRS.2022.11.000760
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Innovation is the application of new solutions to meet new requirements or needs. It differs from invention in that innovation refers to using ideas or methods, while invention refers to creating them. Innovation can occur in individuals, societies, businesses, and organizations through sources like changes in markets, demographics, or scientific knowledge. Common goals of innovation programs are improved quality, new markets, and reduced costs, though failures can occur from issues like poor goal definition, participation, or monitoring of results. Innovation is measured globally using indexes that rank countries based on factors like research and development spending and patent activity.
Hashaam Masood is applying for a position at the hiring company. He has over 5 years of experience as an entrepreneur, software engineer, and manager of industrial relations. He developed several software projects for healthcare, mobile apps, and web interfaces. Masood believes his passion, skills, and experiences would make him an asset to any organization. He is seeking an interview to further discuss the opportunity.
R&D To Commercialisation - LSX C-Suite Challenges in Life Sciences Survey 201...Covance
Learn key insights from biotech executives about their path from R&D to commercialisation in this whitepaper, part of the LSX C-Suite Challenges in Life Sciences Survey 2018 report.
This document provides an overview of marketing strategies for early-stage biotech startups. It discusses how early-stage marketing can assess market potential and address investor concerns. Key aspects of a marketing portfolio are outlined, including market research, branding, pitch decks, and gaining exposure. Early-stage marketing goals are highlighted as well as metrics that are important to investors like market opportunity, proven traction, team strengths, and unique value proposition. Resources for market research and positioning are also provided.
12.5.18 "How For-Profit Companies Can Be a Part of the Open Environment" pres...DuraSpace
"How For-Profit Companies Can Be a Part of the Open Environment"
DuraSpace Members Hot Topics webinar
Presented on 12.5.18
Presented by: Andrew Smeall of Hindawi, Brian Hole of Ubiquity Press and Anita Bandrowski of SciCrunch
The Arrowhead Center at New Mexico State University works to create an innovation-driven economy through research, business development, education and policy analysis. It conducts research to move ideas to market, supports startups and growing companies, and provides hands-on learning for students. The Center launches new ventures through programs like Launch and manages Arrowhead Park, a research and business park. It also analyzes economic and policy impacts and facilitates technology transfer from NMSU to the private sector.
Teaching Students To Write A Persuasive EssayRosa Williams
The document outlines the steps for seeking writing help from HelpWriting.net, which includes registering for an account, completing an order form with instructions and deadline, and reviewing writer bids before choosing one and placing a deposit to start the assignment. It notes that customers can request revisions until satisfied with the paper and are ensured original content or a full refund.
1. The document discusses challenges that financial institutions face when adopting external innovations from startups and vendors. It explores issues such as risk management, cultural differences, and long sales cycles.
2. It identifies "leaks" in the innovation process where collaboration is lacking between innovators and customers during problem identification and solution testing. It also finds issues with startups successfully adopting their solutions.
3. Potential solutions discussed include financial institutions being more open to startups they have existing relationships with, startups employing staff with customer knowledge, and partnering with companies that complement their solutions and have customer connections.
Analysis of drivers that cause restricted access to funding for smaller biotech companies.
A detailed reviewed of the steps
venture capitalists and companies are
taking — models such as fail-fast R&D, asset-centric funding and more.
Proposal of a model that
could radically change R&D by taking a
much more holistic approach to drug
development, sharing information to
learn in real time across the cycle of care
and fundamentally changing how risk
and reward are allocated.
“The Most Recommended Pharma & Life Sciences Solution providers in 2021” highlighting the pharmaceutical and healthcare industries help to improving the human health and forwarding life-expectancy one step further.
This document provides an agenda and overview for the fourth Innovation Louisiana conference being held November 14-15 at the BioInnovation Center in New Orleans. The conference will feature panels on topics relevant to life sciences entrepreneurs such as lessons from experienced biotech founders, intellectual property protection, venture capital, and developing partnerships. Keynote speakers will discuss determining the right market fit and research partnerships. The goal is to help attendees hone their business strategies, find funding, and make connections to further commercialize their innovations. A technology showcase and pitch competition are also planned.
Program from the Innovation Louisiana 2013 life sciences entrepreneurship conference, presented by the New Orleans BioInnovation Center. Featuring sessions on startup funding, legal issues for growth startups, technology transfer, and other issues affecting life sciences startups
The Innovation Commercialization Process:A Case StudyCheryl Tulkoff
When people think of innovation, they frequently think of the “big idea” or product while overlooking the fact that innovation is really a process.
They think of innovation solely in the creative sense rather than considering the importance or even existence of an innovation methodology.
Countless examples exist of good inventions that never succeeded in the marketplace or failed to live up to expectations while lesser ones thrived.
Many of these failures could have been eliminated through use of an innovation commercialization process.
This presentation describes the process and demonstrates its application through a case study.
Academia is the single largest untapped resource for addressing unmet global needs. In the age of the so called knowledge economy, they have the capacity and opportunity to drive global change. Question is............. as largely publicly funded, free to do as they please researchers, do they have the strategy and courage to implement change.
The document discusses achieving excellence in product development and launch. It provides context on the challenges facing the pharmaceutical, consumer goods, and retail industries in developing and launching new products given dynamic market conditions. It identifies key lessons that can help businesses, including focusing on critical success factors, embedding launch capabilities, navigating uncertainty, and getting launch fundamentals right. Digital technologies, customer insights, and adapting operating models are also discussed as important to maintaining speed to market and innovation. The document covers industry dynamics, digital technologies, and future operating models as they relate to product development and launch excellence.
Major pharmaceutical companies are reinventing their early-stage research and development through open innovation models. This includes establishing regional innovation hubs and centers that identify promising early-stage innovations and establish novel collaborations. For example, Johnson & Johnson, Merck, and Pfizer have set up innovation hubs in locations like Boston, London, and Shanghai. China in particular represents a large market and talent pool for innovation, with the government strongly supporting initiatives in areas like recruiting top talent and funding major new drug development projects. Johnson & Johnson and WuXi AppTec are collaborating through an accelerator program that pairs scientific assets and entrepreneurs to form new companies developing transformational products in China for the global market.
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A crisp presentation on Innovation, its definitions, meaning and how to ' manage innovation' as a Manager / Executive within a business organization / company
In this issue, “The 20 Best Tech Companies to Work for in 2019” we’ve enlisted some such companies which have initiated an appreciable level of ethical standards in their organizations.
The article discusses how data and new technologies are enabling innovation like never before. It outlines several key points:
1) The amount of digital data from various sources is massively increasing, including data from IT systems, research databases, patent filings, and new sources like social media and the Internet of Things.
2) Collaboration platforms and crowd-sourcing tools can help organizations assess, prioritize, fund, and realize innovation opportunities by pulling insights from various participants.
3) A wide range of data sources must be harnessed for insights, including repositories, exchanges, unstructured data, social media, sensor data, and more. Both looking back longitudinally and forward visioning with rapid prototyping
Similar to ACS SCHB abstracts acs 246nm Indianapolis Meeting (20)
Terahertz (T-ray) techniques for measuring, profiling, and mapping of semiconductor features and doping concentration of via a T-ray volume imaging route, deep-level spectroscopy, and empirical modeling; and application thereof for semiconductor doping concentration thickness profiling and surface mapping for both undoped and doped semiconductors.
This paper outlines the basic technology and economic model of the core silicon technology. Silicon is the second most abundant element on the earth’s crust but there is no specific deposit or mine for silicon.
The only source for silicon is “sand” that the earth has an abundant supply. Here we outline the basic steps of manufacturing silicon ingot and wafers. It is projected that, once produced, these products will gain immediate market access, thus creating economic activities in a reasonably short period of time. The three initial products that could stem from the basic silicon ingot are silicon wafers, for both semiconductor and solar cell applications, and optical fiber for communication. This report focuses on the essential silicon
technology to produce silicon ingot, and silicon wafer, as the first step. Finally, the historic data available for the silicon wafer consumption per year have been modeled with the well-known Bass diffusion model.
It was found that with modified parameters, the Bass model fits the historic data well and the same model allows a projection for a few years in the future. This projected economic activities, therefore, encourages a social transformation towards a technological self-sufficiency.
Keywords: Silicon technology; Bass diffusion model; Silicon wafer consumption; Social transformation;
Technological self-sufficiency
DOI: 10.31031/NRS.2022.11.000760
Abstracts and Bios of the Chief Guest, Guest of Honor, distinguished Speakers and Panelists of the 2021 AABEA-FOBANA joint Seminar in Washington DC, November 27 and 28, 2021.
This document summarizes the results of a study that used terahertz imaging to quantify the lattice dilation of plasma-sprayed nickel films in four samples. The study found that the lattice spacing of the nickel films was greater than that of pure metallic nickel, indicating lattice dilation. The degree of dilation decreased in the order of the four samples and was correlated with their exposure to high energy electric fields. This provides direct evidence of lattice dilation in plasma-sprayed nickel due to experimental conditions.
The document reviews some of the highlights from the author's 2018, including two notable papers that were published. The first paper, published in the IEEE Transactions on Semiconductor Manufacturing, outlines a technique for nano-scale imaging and measurements without an electron microscope that overcomes the Abbe diffraction limit. A second paper published in the Journal of Nanoparticle Research addresses advances in nanoparticle imaging while suspended in a medium, and formally acknowledges the "Rahman-Tomalia effect". Both papers received positive feedback from colleagues in their respective fields.
Abstract— This paper demonstrates overcoming of the Abbe diffraction limit (ADL) on image resolution. Here, terahertz multispectral reconstructive imaging has been described and used for analyzing nanometer size metal lines fabricated on a silicon wafer. It has also been demonstrated that while overcoming the ADL is a required condition, it is not sufficient to achieve sub-nanometer image resolution with longer wavelengths. A nanoscanning technology has been developed that exploits the modified Beer-Lambert’s law for creating a measured reflectance data matrix and utilizes the ‘inverse distance to power equation’ algorithm for achieving 3D, sub-nanometer image resolution. The nano-lines images reported herein, were compared to SEM images. The terahertz images of 70 nm lines agreed well with the TEM images. The 14 nm lines by SEM were determined to be ~15 nm. Thus, the wavelength dependent Abbe diffraction limit on image resolution has been overcome. Layer-by-layer analysis has been demonstrated where 3D images are analyzed on any of the three orthogonal planes. Images of grains on the metal lines have also been analyzed. Unlike electron microscopes, where the samples must be in the vacuum chamber and must be thin enough for electron beam transparency, terahertz imaging is non-destructive, non-contact technique without laborious sample preparation.
Abstract:
This paper demonstrates overcoming of the Abbe diffraction limit (ADL) on image resolution. Here, terahertz multispectral reconstructive imaging has been described and used for analyzing nanometer size metal lines fabricated on a silicon wafer. It has also been demonstrated that while overcoming the ADL is a required condition, it is not sufficient to achieve sub-nanometer image resolution with longer wavelengths. A nanoscanning technology has been developed that exploits the modified Beer-Lambert’s law for creating a measured reflectance data matrix and utilizes the ‘inverse distance to power equation’ algorithm for achieving 3D, sub-nanometer image resolution. The nano-lines images reported herein, were compared to SEM images. The terahertz images of 70 nm lines agreed well with the TEM images. The 14 nm lines by SEM were determined to be 15 nm. Thus, the wavelength dependent Abbe diffraction limit on image resolution has been overcome. Layer-by-layer analysis has been demonstrated where 3D images are analyzed on any of the three orthogonal planes. Images of grains on the metal lines have also been analyzed. Unlike electron microscopes, where the samples must be in the vacuum chamber and must be thin enough for electron beam transparency, terahertz imaging is non-destructive, non-contact technique without laborious sample preparation.
Two critical nanoscale design parameters (CNDPs); namely, surface chemistry and interior compositions of poly(amidoamine) (PAMAM) dendrimers were systematically engineered to produce unique hyperpolarizable, electro-optical substrates. These electro-optically active dendritic films were demonstrated to produce high quality, continuous wave terahertz radiation when exposed to a suitable pump laser that could be used for spectrometry and molecular imaging. These dendrimer based dipole excitation (DDE) terahertz sources were used to construct a working spectrometer suitable for many practical applications including THz imaging and analysis of encapsulated hydrogen species in fullerenes.
Abstract
Terahertz spectral analysis has been conducted on epitaxially grown semiconductor structures. Epitaxially grown semiconductors are important for microelectronic and optoelectronic devices and also for integrated circuits
fabricated using semiconductors. In this paper, we report results of terahertz time-domain spectroscopy of grown
SiGe layers on Ge buffer and separately a Ge buffer that was grown on a Si <001> wafer. In particular, evolution of
the time-domain spectra as a function of thickness of both samples was investigated by the terahertz pump-probe
technique. Representative spectra were analyzed to determine the respective layers’ spectral signatures. It was found that the spectroscopic analysis uniquely identified different layers by characteristic absorbance peaks. In addition, terahertz imaging was conducted in a non-destructive, non-contact mode for detecting lattice stacking fault and dislocations. Sub-surface imaging of grown SiGe layers on Ge buffer and that of the Ge buffer grown on a Si wafer reveals interesting lattice features in both samples. A comparison with TEM images of the samples exhibits that the terahertz image reproduces the dimensions found from TEM images within the experimental error limits. In particular, 3D images of both samples were generated by the terahertz reconstructive technique. The images were analyzed by graphical means to determine the respective layer thicknesses. Thus, this technique offers a versatile tool for both semiconductor research and in-line inspections.
The document discusses observations of patterns in nature that suggest nature exhibits short-range order and long-range disorder. Samples of fabric and paper with particles distributed in grids were found to have irregular particle patterns that did not continue across whole layers. Google Earth images also showed tree distributions forming grids in sparse areas that disappeared in denser areas. Random forest and park images from around the world provided further examples, supporting the hypothesis that nature favors short-range order transitioning to long-range disorder over large scales.
Abstract
Terahertz sub-surface imaging offers an effective solution for surface and 3D imaging because of minimal
sample preparation requirements and its ability to “see” below the surface. Another important property is the ability
to inspect on a layer-by layer basis via a non-contact route, non-destructive route. Terahertz 3D imager designed
at Applied Research and Photonics (Harrisburg, PA) has been used to demonstrate reconstructive imaging with a
resolution of less than a nanometer. Gridding with inverse distance to power equations has been described for 3D
image formation. A continuous wave terahertz source derived from dendrimer dipole excitation has been used for
reflection mode scanning in the three orthogonal directions. Both 2D and 3D images are generated for the analysis
of silver iodide quantum dots’ size parameter. Layer by layer image analysis has been outlined. Graphical analysis
was used for particle size and layer thickness determinations. The demonstrated results of quantum dot particle
size checks well with those determined by TEM micrograph and powder X-ray diffraction analysis. The reported
non-contact measurement system is expected to be useful for characterizing 2D and 3D naomaterials as well as for process development and/or quality inspection at the production line.
This document describes a new mechanism for terahertz generation using dendrimer dipole excitation (DDE). Dendrimers are doped with chromophores to create multiple distributed dipole moments. When excited by a pump laser, these distributed dipoles radiate across a broadband terahertz frequency range. The document details the design of an electro-optic dendrimer material with a high electro-optic coefficient and second order susceptibility for efficient terahertz generation. It discusses the doping and poling process used to generate the distributed dipoles and align them. Measurement of the electro-optic coefficient and demonstration of terahertz generation from the material is also summarized.
This document summarizes a study that used terahertz spectroscopy to analyze the interaction between different dyes (natural dyes from pomegranate and blackberry, and an inorganic dye called Ruthenium) and titanium dioxide films. The study found that:
1) The terahertz spectra of the natural dye-sensitized films were similar to each other but distinct from the inorganic dye, with prominent absorption peaks around the same wavelengths.
2) The natural dyes permeated more uniformly through the titanium dioxide layers than the inorganic dye based on kinetic studies of dye penetration.
3) Surface profiling and 3D imaging of the films using terahertz radiation clearly showed defects and flaws on the titanium dioxide film.
Abstract: Non-destructive terahertz reflection interferometry offers many advantages for sub-surface inspection such as interrogation of hidden defects and measurement of layers’ thicknesses. Here, we describe a terahertz reflection interferometry (TRI) technique for non-contact measurement of paint panels where the paint is comprised of different layers of primer, basecoat, topcoat and clearcoat. Terahertz interferograms were generated by reflection from different layers of paints on a metallic substrate. These interferograms’ peak spacing arising from the delay-time response of respective layers, allow one to model the thicknesses of the constituent layers. Interferograms generated at different incident angles show that the interferograms are more pronounced at certain angles than others. This “optimum” angle is also a function of different paint and substrate combinations. An automated angular scanning algorithm helps visualizing the evolution of the interferograms as a function of incident angle and also enables the identification of optimum reflection angle for a given paint-substrate combination. Additionally, scanning at different points on a substrate reveals that there are observable variations from one point to another of the same sample over its entire surface area. This ability may be used as a quality control tool for in-situ inspection in a production line.
Electro-optic Dendrimer is used to generate milliwatts of terahertz power by difference frequency
method. A terahertz time-domain spectrometer (THz-TDS) has been designed around this source that
exhibits wide broadband terahertz range, 0.1 to 35 THz. Examples of molecular characterization are discussed
for three common explosives and the vibrational states of Fullerenes. The explosives’ spectra are
unique for each explosive that allow detection and identification of the species. The Fullerenes C60 and
H2@C60 also exhibit distinctively different spectra and absorbance states indicating that the THz-TDS is
suitable for probing increased number of vibrational states expected from molecular vibrations.
2011 Elsevier B.V. All rights reserved.
http://thz-pacifichem.blogspot.com/
Call for Abstracts
Advances in Terahertz Spectroscopy and Imaging (#413)
THE INTERNATIONAL CHEMICAL CONGRESS OF
PACIFIC BASIN SOCIETIES
Honolulu, Hawaii, USA DECEMBER 15 - 20, 2015
Dear Colleague:
It is our great pleasure to announce a symposium on “Advances in Terahertz Spectroscopy and Imaging” at the Pacifichem 2015 in Hawaii. Please see the link above for details. Contributions are solicited addressing subjects from all walks of terahertz applications. As an emerging area of science and technology, terahertz applications, such as spectroscopy, reflectometry and imaging, have the potential for addressing some of the critical problems of the 21st century. As indicated by increased attendance and number of papers in the past, the proposed symposium will fill a gap in the technical program by attracting the terahertz spectroscopy and related communities from all over the world. While there are other spectroscopic techniques, terahertz technology provides unique information that is not available from the predecessors. Therefore, this symposium solicits papers on the advances of terahertz applications in crucial matters such as: biomedical research, early detection of skin cancer, transdermal drug delivery, biopharmaceuticals, materials for energy, conservation and forensic science, security & screening, geology and minerals, semiconductors and any other relevant areas. This symposium will present an opportunity for the exchange of knowledge in a global forum, including results and discussions of current and breakthrough terahertz techniques and their applications. Papers, including spectroscopic, reflectometry and imaging techniques on the above mentioned areas and other terahertz applications in solving important problems are welcome. Formal abstracts submission will be open from January 1 – April 3, 2015. See this link for details of submission: http://www.pacifichem.org/congress-details/abstracts/
Sincerely yours,
Anis Rahman (USA): a.rahman@arphotonics.net
Choonho Kim (S Korea): chkim1202@gmail.com
Wolfgang Jaeger (Canada): wolfgang.jaeger@ualberta.ca
Sing Kiong Nguang (New Zealand): sk.nguang@auckland.ac.nz
Yacov Shamash (USA): yacovshamash@yahoo.com
This document describes a terahertz non-invasive sub-surface nano-scanner and 3D imager. It uses terahertz radiation, which can penetrate non-metallic materials, to perform non-destructive subsurface scanning and 3D imaging. Examples are given of using it to detect coating penetration into paint and reveal periodic patterns in semiconductor wafers without defects. The system performs 3D scans to profile sample layers and reconstruct 3D images. It has potential applications in semiconductor inspection, medical imaging of skin and tissue, and other non-destructive testing of non-metallic layered composites.
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1. American Chemical Society
246th National Meeting
Indianapolis, Indiana
September 8-12, 2013
Division of Small Chemical Businesses
ABSTRACTS OF ORAL PAPERS & POSTERS
SUNDAY AFTERNOON
Small Business Chemistry in Motion
G. Arnold, Organizer, Presiding; Paper 1
MONDAY MORNING
SCHB Poster Session
G. Ruger, Organizer, Presiding; Papers 2-4
MONDAY EVENING
Sci-Mix
G. Ruger, Organizer; Papers 2-4
TUESDAY MORNING
True Stories of Success from Chemical Entrepreneurs
G. Ruger, Organizer, Presiding, Papers 5-10
TUESDAY AFTERNOON
STEM Women in Innovation and Investing
J. Bryant, Organizer; J. Maclachlan, Organizer; J. Giordan, Presiding; Papers 11-14
WEDNESDAY MORNING
Applications of Ionic Liquids from the Small Business Sector
S. Seelig, Organizer, Presiding; Papers 15-19
WEDNESDAY AFTERNOON
Biofuels in Motion
K. Andrews, Organizer, Presiding; Papers 20-22
2. SCHB 1 Business of science: How to turn your scientific skill set into a successful
business enterprise
Gianna Arnold1, Garnold@saul.com, Jacqueline L. Allen1, Elizabeth Hart Wells2, Rajesh Nair3, Linda
Sivik4. (1) Saul Ewing LLP, Baltimore, MD 21202,(2) Kurz Purdue Technology Center, West
Lafayette, IN 47906, (3) Saul Ewing LLP, Washington, DC 20006, (4) The Procter & Gamble
Company, Cincinnati, OH 45202.
Join our wide spectrum of speakers for a facilitated presentation and discussion aimed at
assisting you with the business of science. The session will begin with “Best Steps to Business
Success - and Pitfalls to Avoid,” an overview on creating a technology-based company. Further
presentation and discussion will include the elements: creating an organizational structure, various
forms of intellectual property and their use as strategic business assets, roles an expert can fill as a
consultant to an early stage company or as a scientific advisory board member, alternative forms of
compensation as a consultant, key considerations in agreements, technology transfer, industry
collaboration, and much more! This is your opportunity to ensure the success of your new or planned
endeavor.
SCHB 2 Ariadne: A next generation chemical inventory and ELN web application
Valentin O Rodionov, info@moleculenix.com.Moleculenix LLC., United States.
Keeping track of thousands of chemicals in a research lab is not a trivial task. Specialized
inventory software does exist. However, such software is often focused squarely on regulatory
compliance, and is perceived by end users as a burdensome layer of digital bureaucracy.
Laboratories in academia are especially likely to keep vital inventory records in ordinary
spreadsheets, or even on paper. Recently, we introduced Ariadne, a web application combining a
chemical inventory with an electronic lab notebook (ELN). Ariadne assigns the location of every
chemical semi-randomly, based on storage compatibility rules. The system reveals the item location
only after the item has been checked out by the user. Mandatory checkout ensures item movement is
tracked in real time, with no extra effort from users. Ariadne utilizes our JavaScript chemical structure
editor, ChemWidget, to enable structure input in any web browser. This presentation will describe our
experience in developing chemical software for the modern web.
SCHB 3 Benefits of a Division of Small Chemical Businesses membership
Jennifer L Maclachlan1, pidgirl@gmail.com, Stan Seelig1, Mukund Chorghade1, Sharon Vercellotti1,
David Deutsch1, Joseph E Sabol1, Michael Haukaas1, Anis Rahman1, Ronald Versic1, Carlyn Burton1,
George Ruger. (1) Division of Small Chemical Businesses, Sandwich, MA 02563.
The ACS Division of Small Chemical Businesses Division (SCHB) has provided valuable member
benefits and informative programming, featuring small businesses and with resources for small
businesses, at ACS national and regional meetings, since 1977. SCHB member benefits include free
membership for the first year, listing in the SCHB website members' directory of products and services,
deeply discounted ACS national meeting expo booth space the Small Chemical Business Row,
scholarship to the ACS Leadership Courses, the opportunity to shape and direct SCHB, and, the best of
all: amazing networking opportunities in-person at ACS meetings and via SCHB's social media platforms
(ACS Network, LinkedIn, Twitter and Facebook.) Patron [corporate] membership is also available.
SCHB 4 Chemical professionals investing in chemical companies
Mark Vreeke, sidwhite@tampabay.rr.com, Sid White, Judith Giordan.Chemical Angel Network, United
States.
The Chemical Angel Network (CaN) is a nationwide angel investing network for early stage
chemical businesses (ie. businesses with a significant chemistry component). The CaN network offers
chemists, chemical engineers, and chemical professionals a unique opportunity to participate in the
growth of companies in the chemical and related industries. In addition to possibly significant financial
upside opportunities, the CaN network encompasses several unique elements. We anticipate that a
significant number of the qualified investors will be retired or semi-retired chemical professionals. In
3. addition to capital, the network will draw upon the retired and semi-retired member's unique experience
and knowledge base to provide special due diligence, mentoring, contacts, and general technical
expertise. Our hope is that CaN will become the smart capital choice for early stage chemical companies.
SCHB 5 Surviving a start-up by innovation
Anis Rahman, a.rahman@arphotonics.net.Applied Research & Photonics, Harrisburg, PA 17111
In today's world the name of the game is competition. Especially when the ever-changing
world of technology is bringing the next best thing more often, making the state of the art a thing of
past more quickly. However, innovation or having a new idea alone is never sufficient to build and
survive a business. It is important to have a priori knowledge about how the new technology or the
new product will attract target users. An important question is, “why people should consider this
product?” So, the value proposition must be strong. At the same time diffusion of knowledge of the
new technology to the target population is always a challenge. More often than not, new
entrepreneurs lack the foresight, since “success” never is a straight line; as such a great deal of
lessons must be learned the hard way. Some examples will be outlined from a start-up point of view.
SCHB 6 Commercializing your research and finding focus for your start-up using the
teachings of the NSF I-Corps program
Andrew D Basner, adbasner@syr.edu.Department of Chemistry, Syracuse University, Syracuse, NY
13244
The National Science Foundation has supported science and engineering for many years.
Some of this research has the potential for applications in the commercial world but
commercialization is often not realized. To help foster this transition from research to a commercial
product, the National Science Foundation developed the Innovation corps program. Over the course
of an intensive 8 week program, our team talked to over 100 potential customers, defined and
validated a value proposition for clear customer segments, identified revenue strategies and models,
identified the correct channels for our technology, and met with key potential partners. The teaching
team for the NSF I-Corps helped us identify key pitfalls that are common in technology based start-
ups and led us to a single, clear, and focus scalable business model. A number of key ideas from this
program can be used by anyone who is interested in commercializing their research or by anyone
who is in the process of finding an ideal market segment to fit into.
SCHB 7 HESI: Creating science-based solutions for a sustainable, healthier world
Jennifer Young Tanir, jtanir@hesiglobal.org.ILSI Health and Environmental Sciences Institute,
Washington DC, United States.
The ILSI Health and Environmental Sciences Institute (HESI) was established in 1989 as a
global branch of the International Life Sciences Institute (ILSI) to provide an international forum to
advance the understanding of scientific issues related to human health, toxicology, risk assessment,
and the environment. With a vision of creating science-based solutions for a sustainable, healthier
world, HESI recognizes sustainability as vitally important as it identifies and resolves global health
and environmemntal issues through engagement with scientists from academia, government and
industry. As a non-profit organization, HESI provides a unique, objective forum for initiating dialogue
among scientists with different perspectives and expertise from a range of sectors including
pharmaceuticals, agricultural and industrial chemicals, personal care and consumer product, and
others. HESI's broad scientific portfolio spans translational biology, new approaches and techniques,
environmental toxicology, and risk assessment. Using a committee structure to engage scientists,
supported by expert staff with advanced scientific degrees, HESI enables hundreds of scientists to
work together to address public health needs, from 49 corporate sponsors, 70 universities, 32
government agencies (international, national, and state), foundations and non-governmental
organizations, by a financially viable model. This presentation will highlight several of HESI's success
stories.
4. SCHB 8 Building a microencapsulation company: A 35 year history of controlled release
Ronald J Versic, Rversic@RTDodge.com Ronald T. Dodge Company, Dayton, OH 45459.
In the spring of 1979 the author started out with USD 500 and a desire to build a company
based upon the principles of (1) multiple microencapsulation capabilities, a desire to (2) manufacture
microcapsules and (3) scientific soundness. The results for this international company are described
along with the difficult path to the current business status.
SCHB 9 History of NanoVir, LLC, a drug discovery company supported by the NIH and
grown partly through interactions with academia
James K Bashkin, bashkinj@umsl.edu Department of Chemistry, NanoVir, LLC, Saint Louis, MO
63121, United States Department of Chemistry & Biochemistry, Center for Nanoscience, University of
Missouri-St. Louis, Saint Louis, MO 63121.
NanoVir LLC is a company that was started jointly by a chemist (myself) located in St. Louis
MO and a biologist (Dr. Chris Fisher) located in Kalamazoo MI. Our purpose was the discovery and
development of antiviral agents suitable for therapy against high-risk, cancer-causing human
papillomavirus (HPV). In order create the company, we co-wrote a Phase I small business proposal
to the National Institutes of Health and also submitted a proposal to the Biosciences Research &
Commercialization Center (BRCC) funded by the State of Michigan. We were successful with our first
NIH proposal and the BRCC proposal, allowing us to begin work as a real company. Our
headquarters and Biology Department are located at the Southwest Michigan Innovation Center in
Kalamazoo. Since I had held the position of Research Associate Professor in Chemistry &
Biochemistry at the University of Missouri-St. Louis, we were able to establish and grow the company
under the STTR mechanism, with chemistry done under subcontract to the University. Now, after two
Phase I and two Phase II NIH STTR grants, we have a large set of active compounds with IC50
values in the 8-40 nM range, and many more with IC50s below 100 nM. Furthermore, we have a pair
of compounds in preclinical development and a significant patent estate. The basis of our work is the
design, synthesis and testing of sequence-selective DNA binding molecules that target key
interactions between viral proteins and the viral genome, which is a double-stranded circular DNA
molecule of about 8 kb. Chemistry and biology have been tightly integrated throughout the entire
program, and this has contributed significantly to success. For the purpose of animal studies, we
have scaled up compound synthesis and have tested a wide range of formulations on differentiated
human tissue cultures, organotypic cultures, grown from keratinocyte monolayers.
SCHB 10 50 years of success at Nice Pak Products
Rick West, rick.west@nicepak.com.Nice Pak Products, Orangeburg, NY 10962.
Nice Pak Products / PDI was started a little over 50 years ago by the Julius family and is still
privately owned today. During that time, it has grown from a one room operation in NYC to where it is
today- locations in NY, IN, AR, and a facility currently being built in China. Nice Pak produces
products for the healthcare sector and also for the household sector. Some of the more interesting
product lines will be discussed. Currently, Nice Pak produces approximately three billion wipes a
year. The relative volume of liquid batches produced and some annual chemical consumption data
will be provided. Some of the company's success stories and a few difficulties will be discussed.
SCHB 11 Challenges and opportunities in technology transfer: How are STEM women faring?
Mary Foley Phillips, Mary.Phillips@oregonstate.edu.Office for Commercialization and Corporate
Development Research Office, Oregon State University, Corvallis, OR 97331
As Associate Director for the Office for Commercialization & Corporate Development at Oregon
State University (OSU), Dr. Mary Foley Phillips is responsible for overseeing the management of
intellectual property and licensing of OSU inventions. Dr. Phillips will discuss her perspectives on the
challenges and opportunities in technology transfer for commercializing technology, and will discuss her
views and share insights on how women are faring and can continue to thrive in this environment.
5. SCHB 12 Challenges of starting (and growing) a start-up
Nicola L. Pohl, npohl@indiana.edu.Chemistry, Indiana University, Bloomington, IN 47405.
Starting a company is easier than growing it into a success. This talk will focus on the challenges
encountered in founding LuCella Biosciences, Inc., a carbohydrate-focused biotechnology company that
sprung out of university-related research.
SCHB 13 Women-led ventures: Insights from the X Squared Angels Group
Carol Clark, carolahclark@gmail.com X Squared Angels Group, Columbus, OH 43212.
Carol Clark's entrepreneurial roots date back to 1981 when she and Fran Papalios co-founded
MindLeaders, an online software training company that was sold in 2007. Taking what she learned, Carol
became an angel investor and member of several well-known and influential angel groups, including the
Ohio TechAngel Funds, Golden Seeds and Investors' Circle. One of latest endeavors is founding the X
Squared Angels Group - focused on women-led ventures. Carol's background and perspective as both a
female angel investor (who seriously intends to help other women) and as an entrepreneur will help you
gain the insights you need to succeed - whether it is to move your idea ahead or to understand the roles
you, as a women in STEM, can play in technology commercialization. Carol also currently serves on the
College of Arts and Sciences Technology Review Board at the Ohio State University where ideas and
inventions are vetted for commercialization.
SCHB 14 Issues women face in research and commercialization from academia: Personal
insights from a successful company founder
Kathryn Uhrich, keuhrich@rutgers.edu.Mathematical & Physical Sciences (SAS), Rutgers University,
Piscataway, NJ 08854
As Professor of Chemistry and Dean of Mathematical & Physical Sciences (SAS) at Rutgers
University, Dr. Kathryn Uhrich's research focuses on synthesis and characterization of biocompatible,
biodegradable polymers for medical, dental, cosmetic and personal care applications. In 2000 she co-
founded Polymerix Corporation, a specialty pharmaceutical company developing and commercializing
PolyNSAIDs as coatings for implanted medical devices, such as orthopedic implants, sutures, surgical
meshes, coronary stents, and vascular grafts, as well as long-acting formulations for drug delivery. As a
chemistry professor, dean and company founder, Dr. Uhrich has a unique perspective on the issues
women face in research and commercialization from academia – and she will bring to the discussion her
insights into how women can succeed on all of those fronts.
SCHB 15 Green solvents and ionic liquids: A business venture for the global conservation of
water
Stanley S Seelig, SSSeelig@aol.com. Seelig and Associates, Lakeland, FL 33810.
Over the last 50 years (or longer) many processes were defined as solvent or water processes (or
solventless or waterless). The halogenated solvents were beneficial as excellent cleaners with recyclable
and reclaimable processes but many had toxicity, ozone depletion or global warming issues. Then many
companies switched back to water based processes only to have to deal with poor cleaning, waste
streams, and excessive surfactants. Now there is an option to switch to green(er) solvents on a global
basis. How can this approach lead to a successful business venture? We will discuss a number of green
solvents and their processes and how they are changing the world away from excessive waste water
streams and assisting to preserve the conservation of water. From laundry to dishwasher to toilets and
more, closed-loop solvent processes are a wave in the future. Water treatment plants are working at
maximum to keep up with technology. Green solvents can relieve some of that pressure. And small
businesses will provide the answers.
6. SCHB 16 Separation of hydrocarbons from sand or other minerals using ionic liquids
Paul Painter, pcp1@psu.edu, Bruce Miller, Aron Lupinsky, Maria Sobkowiak, Andrea Choperena,
Nuerxida Pulati.The E&MS Energy Institute, Penn State University, University Park, PA 16802.
The separation or extraction of hydrocarbons such as oil and bitumen from soil, sand, or other
forms of mineral matter is a difficult and expensive process that also results in environmental problems
associated with the disposal of waste products. For example, the separation of bitumen from tar or oil
sands involves large amounts of energy and water. The process water generated in the separation is toxic
to aquatic life and is a major environmental problem. Similarly, the oil and gas industry has to deal with oil
contaminated sand, waste drilling muds and drill cuttings in its operations. We have developed a novel
method for separating bitumen, oil or other hydrocarbons from sand or soils through the use of ionic
liquids (ILs). The separation occurs at ambient temperatures and does not result in the generation of
significant quantities of waste process water. A preliminary patent application and a continuation in part
describing the use of analogue ILs has been filed by the Penn State Research Foundation (PSRF) and a
small company, IL Fuels LLC, founded to develop the technology. The company was granted an exclusive
license to the technology from PSRF in exchange for a 5% equity stake. Some investment funds have
been raised and a small pilot/demonstration unit built at Penn State. Potential licensees are now using the
pilot unit for tests. Conversations with other potential investors and the patent office have been interesting.
The presentation will elaborate on the problems we have faced.
SCHB 17 Production of ionic liquid based electrolytes for electrochemical storage devices
Joe C Poshusta, joe.poshusta@boulderionics.com. Boulder Ionics, Arvada, CO 80007.
Ongoing research and development in electrochemical storage devices strives to improve their
capacity, longevity, environmental resilience, and safety. With their wide electrochemical window and low
vapor pressure, electrolytes containing room temperature ionic liquids are a key enabling technology
common to all of these improvements. Electrochemical device applications impose stringent purity
requirements on the electrolyte in order to maintain device lifetime. In particular, halide and water
contamination cannot be tolerated above a few ppm by weight. Conventional ionic liquid synthesis often
involves solvent based reactions, halide intermediates, and repetitive batch-wise purification to achieve
electrochemical device requirements. While able to synthesize a wide variety of ionic liquids, these labor
intensive and time consuming methods drive up cost, leading many device manufacturers to reject ionic
liquids. Boulder Ionics has developed alternative synthetic routes adapted to scalable continuous
processing techniques that can provide electrochemical grade ionic liquids in system residence times of
just minutes. While vastly reducing labor cost, the continuous approach also enables tight process control
and minimizes product handling, producing a high purity material. Ionic liquids and salts of interest for
electrochemical devices include the fluorinated anioIns bis(trifluoromethyl sulfonyl)imide (TFSI) and
bis(fluorosulfonyl)imide (FSI). These anions are often paired with pyrolidinium and imidazolium based
cations in ionic liquids, while their lithium salts are useful in lithium and lithium-ion batteries. The TFSI
anion has been commercially available for several years, but its cost can dominate the ionic liquid material
cost. We have developed a scalable synthetic route to the much less expensive FSI anion, while at the
same time proving to meet performance requirements as demonstrated by our development partners and
other researchers. This presentation will review some of the performance capabilities of FSI based ionic
liquids in electrochemical storage devices as well as discuss synthetic approaches to manufacturing
related electrolyte systems.
SCHB 18 Using academic resources to expand your chemical enterprise: Graphenics, LLC
example
Rachel M Frazier1,2, rmfrazier@bama.ua.edu, Hunter Adams2, Dan T Daly1. (1) Alabama Innovation and
Mentoring of Entrepreneurs, The University of Alabama, Tuscaloosa, AL 35487, (2) Graphenics, LLC,
Tuscaloosa, AL 35487.
Ionic liquids (ILs) have numerous applications, making them ideal materials for platform
technologies. A key challenge to any new material is advancing from the laboratory to the marketplace,
thereby bridging the gap from proof-of-concept to prototype. ILs are no exception to this process, thus we
explore the developmental part Alabama Innovation and Mentoring of Entrepreneurs (AIME) plays in
7. transitioning ILs from invention to innovation. We will explore the vital role AIME has played in helping to
set up Graphenics, LLC for success. Exfoliation of graphite in ILs to produce graphene has been identified
as having significant potential for success and AIME has assisted in developing the technology beyond
proof-of-concept. We will present the translation of this technology from academia to the marketplace and
a case study of a new chemical enterprise, Graphenics. Graphenics, LLC provides graphene materials
and consulting services to both academia and industry. Graphenics core strength is the expertise in the
exfoliation of graphite and the know-how of the proprietary process technology.
SCHB 19 Novel chitin fibers for wound care
Robin D Rogers, rdrogers@as.ua.edu, Gabrielle Gurau.AIME, University of Alabama, Tuscaloosa, AL
35405.
525 Solutions, Inc., a faculty start-up incubated at The University of Alabama with a mission to
transfer fundamental research into new business enterprises while providing opportunities for students
and staff to become entrepreneurs, proposes to use the newly discovered property of ionic liquids (ILs;
salts which melt below 100 oC) to dissolve high molecular weight chitin directly from biomass to design
novel composite fibers of natural polymers with embedded additives to improve the immune system and
facilitate wound healing. 525 Solutions, Inc., will use the proprietary process to directly dissolve
biopolymers (e.g., chitin, alginate, etc.) with or without functional additives into homogeneous solutions
which will allow for the direct dry-jet wet spinning of composite materials.
SCHB 20 CO2 recycling using microalgae for the production of liquid fuels
M. M Crocker1, mark.crocker@uky.edu, M.H.W. Wilson1, J. Groppo1, A. Placido1, S. Graham1,
A. Santillan-Jiminez1, T. Morgan1, J. Shoup1, D. Kim1, L. Mills1, H. Y Shin1, C. Crofcheck2. (1) Center for
Applied Energy Research, University of Kentucky, Lexington, KY 40511, (2) Department of Biosystems &
Agricultural Engineering, University of Kentucky, Lexington, KY 40511.
Given the potential of microalgae for recycling CO2 into bio-products, coupled with the large
number of coal-fired power plants in Kentucky, the Commonwealth of Kentucky's Department of Energy
Development and Independence tasked the University of Kentucky with determining the technical and
economic feasibility of algae-based carbon capture and utilization in Kentucky. These research efforts
have led to the development and on-going deployment of a pilot-scale photobioreactor system at Duke
Energy's East Bend station. This pilot-scale project is focused on process development/improvement,
power plant integration, and the implementation of strategies to increase algae growth rates. The system
is continuously monitored and the process data analyzed to gain insights into system dynamics and to
improve the operation/design of future units. In tandem, we have developed a protocol for the harvesting
and dewatering of algae (with minimal energy input) based on flocculation-sedimentation. Methodologies
have also been developed for lipid extraction (from dry and wet algal biomass) and for the conversion of
extracted lipids to liquid hydrocarbons by means of catalytic deoxygenation.
SCHB 21 Microflotation for microorganism harvest
James O. Hanotu, j.hanotu@sheffield.ac.uk, William B.J. Zimmerman.Perlemax Ltd., Sheffield, United
Kingdom.
Microbial cells or microorganisms are grown in bioreactors under conditions where they thrive and
flourish, yielding a wide range of desired end products. Yeast, Bacteria and Algae are some of the most
widely explored microorganisms and have been applied for food, water remediation and biofuel
production. After the appropriate number of generations, the mature cell mass is separated from the spent
liquid, then delivered as liquid cream, filtered, and sold as compressed forms or filtered and dried into
instant dry cells. On occasions when a heterogeneous community is cultured, selective harvesting can
possibly be employed to recover only the desired organism(s). The conventional approach to extracting
cells from their growth medium is by centrifugation and filtration. However, these methods are expensive
and often unsuitable for continuous large-scale production. Conversely, traditional flotation separation
techniques (such as Dissolved Air Flotation) are regarded as both intrusive and energy intensive, and are
only naturally suitable for portable water treatment. Our microflotation technique is advantageous due to
its laminar flow process, its non-intrusiveness, and scalability to meet continuous industrial production
8. requirements. The efficacy of microflotation has been demonstrated for algal biomass recovery, as well as
for yeast, showing optimum recovery rates comparable to ideal flotation separation results.
SCHB 22 Integrated energy parks as a model for rural economic development and energy
diversification in the Appalachian coalfields
Roger Ford1, roger.ford@patriotbioenergy.com, Eric Mathis2. (1) Patriot Bioenergy Corporation, Pikeville,
KY 41501, (2) Emergy Holdings, Inc., Williamson, WV 25661.
Patriot Bioenergy Corporation and Emergy Holdings, Inc. have developed a business model that
provides diversified energy production on post-mining land in the Appalachian coalfields termed Integrated
Energy Parks. Through integration of energy resources, the business model couples solar, natural gas,
and biomass to generate electricity and to produce energy-related products on post-mining land. As a
start-up, we discuss the challenges associated with regulatory barriers and construction of such facilities,
as well as the discussion of the dynamics that move us toward energy diversification and integration in the
heart of the Appalachian coalfields. Issues discussed include production of sufficient biomass feedstock,
post-mining land use, market-based sustainability strategies, and adoption of an 'all-of-the-above' energy
policy framework.
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