Physician assistants and nurse practitioners both provide medical care but have some key differences in their education, scope of practice, and philosophy of care. Physician assistants receive advanced medical training focused on diagnosis and treatment, with an emphasis on the biological model of health. In contrast, nurse practitioners receive advanced nursing education with a biopsychosocial model and focus on health promotion. Physician assistants require physician supervision, while nurse practitioners have more independent practice authority but need supervision for delegated medical acts. Both roles require national certification and ongoing continuing education for licensure renewal.