Due to rapid unplanned development, versatile land use, rapid population
growth, poor public transport system and increase of private car users, traffic
problems are worsening day by day. The only mass transit is bus which is
insufficient in terms of safety, capacity, comfort, and convenience. Considering
the worsening congestion, it is high time to develop effective mass transit
system such as Bus Rapid Transit (BRT) as a means for achieving sustainable
urban transport in the city
Due to rapid unplanned development, versatile land use, rapid population
growth, poor public transport system and increase of private car users, traffic
problems are worsening day by day. The only mass transit is bus which is
insufficient in terms of safety, capacity, comfort, and convenience. Considering
the worsening congestion, it is high time to develop effective mass transit
system such as Bus Rapid Transit (BRT) as a means for achieving sustainable
urban transport in the city
Transit Oriented Development is the exciting fast growing trend in creating vibrant, livable, sustainable communities. Also known as TOD, it's the creation of compact, walkable, pedestrian-oriented, mixed-use communities centered around high quality train systems.
transit oriented development california
transit oriented development principles
examples of transit oriented development
transit oriented development abstract
transit oriented development case studies
transit oriented development hawaii
transit oriented development seattle
transit oriented development benefits
When evaluating mass transit options for Indian cities, metro rail systems are given preference over surface systems due to the belief that road-based bus systems cannot cater to the capacity requirement as much as metro systems can. In addition, metro rails are perceived to have higher levels of comfort, speed, and efficiency than bus systems.
A documentation of our study, critical appraisal and analysis of the area around the Rourkela Railway Station and the attempt to transform the zone into a Multi-Modal Hub keeping in purview the close proximity of the Bus Station and Intermediate Public Transport service.
Mass transit system refers to public shared transportation, such as trains, buses, ferries etc that can commute a larger number of passengers from origin to destination on a no-reserved basis and in lesser time. It can also be termed as Public Transport.
Effective learning from delhi brts –a case study of pune brtseSAT Journals
Abstract This paper emphasizes on the common problems endured by Delhi and Pune BRTS corridor. Urban Traffic commutation has an eloquent place in urban life. BRTS is a very old form of public transport, but it is still a new concept for developing countries like India, because of its psychological aspects. Bus Rapid Transit involves synchronized improvements in a transport system’s infrastructure, equipment, working, performance and technology that give preference to buses on urban roadways. This paper gives an overall outlook of Delhi and Pune BRT systems and observed some common problems in operating both the system, and some recommendations are mentioned so that could help improving Pune BRTS immensely and influentially and have a better result avoiding bottlenecksthose faced byDelhiBRTS.The main present study intent to highlight the problems and to overcome those problems. Keywords: Delhi and Pune BRTS Bottlenecks, Public Transport, Feeder, Social Image
International Journal of Computational Engineering Research (IJCER) is dedicated to protecting personal information and will make every reasonable effort to handle collected information appropriately. All information collected, as well as related requests, will be handled as carefully and efficiently as possible in accordance with IJCER standards for integrity and objectivity.
Transit Oriented Development is the exciting fast growing trend in creating vibrant, livable, sustainable communities. Also known as TOD, it's the creation of compact, walkable, pedestrian-oriented, mixed-use communities centered around high quality train systems.
transit oriented development california
transit oriented development principles
examples of transit oriented development
transit oriented development abstract
transit oriented development case studies
transit oriented development hawaii
transit oriented development seattle
transit oriented development benefits
When evaluating mass transit options for Indian cities, metro rail systems are given preference over surface systems due to the belief that road-based bus systems cannot cater to the capacity requirement as much as metro systems can. In addition, metro rails are perceived to have higher levels of comfort, speed, and efficiency than bus systems.
A documentation of our study, critical appraisal and analysis of the area around the Rourkela Railway Station and the attempt to transform the zone into a Multi-Modal Hub keeping in purview the close proximity of the Bus Station and Intermediate Public Transport service.
Mass transit system refers to public shared transportation, such as trains, buses, ferries etc that can commute a larger number of passengers from origin to destination on a no-reserved basis and in lesser time. It can also be termed as Public Transport.
Effective learning from delhi brts –a case study of pune brtseSAT Journals
Abstract This paper emphasizes on the common problems endured by Delhi and Pune BRTS corridor. Urban Traffic commutation has an eloquent place in urban life. BRTS is a very old form of public transport, but it is still a new concept for developing countries like India, because of its psychological aspects. Bus Rapid Transit involves synchronized improvements in a transport system’s infrastructure, equipment, working, performance and technology that give preference to buses on urban roadways. This paper gives an overall outlook of Delhi and Pune BRT systems and observed some common problems in operating both the system, and some recommendations are mentioned so that could help improving Pune BRTS immensely and influentially and have a better result avoiding bottlenecksthose faced byDelhiBRTS.The main present study intent to highlight the problems and to overcome those problems. Keywords: Delhi and Pune BRTS Bottlenecks, Public Transport, Feeder, Social Image
International Journal of Computational Engineering Research (IJCER) is dedicated to protecting personal information and will make every reasonable effort to handle collected information appropriately. All information collected, as well as related requests, will be handled as carefully and efficiently as possible in accordance with IJCER standards for integrity and objectivity.
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Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
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Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
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roads and traffiertxcvcxzyuiop[pytrewcsdfg studies.pptx
1. Traffic congestion is a condition in transport that is characterised by slower speeds, longer trip times, and
increased vehicular queueing
What is traffic congestion
Traffic problems in India
The average income of Indians is growing and thereby the number of privately owned vehicles is rising.
Though public transport is widely available in India, still it is not sufficient for the population of India. Especially in Metro cities, often public transport services are
crowded
Lack of parking spaces: Due to lack of parking spaces people are forced to park their vehicles in front of the buildings often encroaching roads.
Poor quality of roads is also one of the causes. Often this leads to repairs and thereby reducing the usable space.
Lack of proper implementation of traffic rules
Due to lack of footpaths in many places, pedestrians are forced to walk on the edge of roads which further increasing traffic issues
Regional inequality in economic development and creation of jobs is concentrated only in some areas. This results in the increasing density of population in
metro cities
2. Solutions
• Distributing and diverting traffic by innovative methods such as constructing flyovers in the busy areas etc.
• Improving the public transportation system.
• Making the construction of parking spaces and footpaths mandatory.
• Proper Implementation traffic rules.
• Increasing taxes on privately owned vehicles also helps, but attracts so much criticism.
• Developing small towns to prevent the push factor of migration to cities.
3. Passenger Car Unit (PCU) is a relative weightage factor given to the traffic volume of individual vehicle category to deal
with the heterogeneity in a mixed traffic situation.
What is Passenger Car Unit (PCU)
It is a vehicle unit used for expressing highway/road capacity.
Number of vehicles crossing a point on the road during a specific time period. It is carried out for :
1.Design and extension of existence road,
2.Traffic trend and pattern,
3.Geometric and structural design of new road,
4.Design of footpath, cross wall,
5.Pedestrian signals,
6.Plan of one way traffic
7.Other regulatory measures on the road
Type of Vehicle PCU
Car, taxi, pick up 1.0
Cycle, motor cycle 0.5
Bus, truck, 3.0 (4.o in some cases)
Horse drawn cart 4.0
Bullock cart 6.0
Bullock cart (Large) 8.0
4. Traffic Volume is defined as the procedure to determine the volume of traffic or no. of vehicles moving on the
roads at a particular section during a particular time period.
Traffic volume survey is the determination of the number, movement and classification of. roadway vehicles at a
given location.
Purpose of Traffic Volume Study is for Structural design of roads. Planning and design of new streets. Planning, design
and regulation of traffic.
What is Traffic Volume
5. The maximum traffic flow obtainable on a given roadway using all available lanes.
Maximum number of vehicles (PCU) that can pass a given point on a lane or roadway during one hour under the most
nearly ideal roadway and traffic conditions which can possibly be attained.
What is Road Capacity
C = 1000*V/S, one can easily determine the Theoretical Maximum Capacity. Here, C = Capacity of a single lane,
vehicle per hour. V = Speed, kmph; S = Average center to center spacing of vehicles, when they follow one behind
the other as a queue or space headway
6. Types of Road (Rural)
I. National and State Highways
II. Major District Roads and other District Roads
III. Village Roads
7. Types of Road (Urban)
Types of Roads Suggested Minimum Spacing
Expressways 1000mt.
Arterial Road 500 mt.
Sub-Arterial Roads 300 mt.
Collector Roads 150 mt.
Urban Residential/local
Streets
Free access
On Urban sections, the current Indian Practice is to provide the following minimum spacing between access points
9. INTERSECTIONS
Intersection is an area shared by two or more roads. This area is designated for the vehicles to turn to different directions
to reach their desired destinations. Its main function is to guide vehicles to their respective directions.
I. Uniformity and Simplicity–The design must keep the capabilities and limitation of drivers, pedestrians and vehicles
using intersection. It should be based on a knowledge of what a driver will do rather than what he should do.
II Minimise Conflict Points- any location having merging, diverging or crossing manoeuvres of two vehicles is a potential
conflict point.
• Space separation- by access control islands through channelizing
• Time separation- by traffic signals on waiting lanes
III Safety- The safety of a particular design can best be assessed by studying the frequency with which types of accidents
occur at a particular type of intersection and its correlation with volume and type of traffic
• Provision for vulnerable road users: Pedestrians(including specially abled). Properly sighted traffic islands have the
added advantage that they can be used as refuges by these vulnerable road users especially at intersections on wide
roads.
• Provision of good safe locations for the installation of traffic control devices
IV Alignment and Profile: The intersecting roads shall meet at or nearly at right angle. Intersection on sharp curves should
be avoided
Principles
11. TRAFFIC CALMING SYSTEM
Speed management and traffic calming include techniques such as discouraging traffic from entering certain areas and
installing physical speed reducing measures, such as road narrowing, roundabouts and road humps.
The central theme of Traffic Calming is to reduce the adverse impact of motor vehicles on built up areas. The techniques
usually involve reducing vehicle speeds, providing more space for pedestrians and cyclists, and improving the local
environment.
The basic principle of Traffic Calming remains universal, that is to lower the vehicle speeds in order to reduce accidents,
pollution and enhance livability of surrounding areas.
Necessity of Traffic Calming
Studies have shown that traffic calming can reduce accident levels by up to 40 per cent, and have a significant impact on
reducing the severity of accidents, economic loss and air pollution .“
The main advantage of traffic calming is that it is self-enforcing and does not normally require any complication traffic control
devices and is usually highly cost-effective; achieving benefits with a value far greater than the costs.
13. MASS RAPID TRANSIST SYSTEM
'Mass Rapid Transit' (MRT) is a term used to describe modes of urban transport (both road and rail based) that carry
large volumes of passengers quickly.
Rapid transit or mass rapid transit (MRT), also known as heavy rail, metro, subway, tube, or underground, is a type of
high-capacity public transport generally found in urban areas.
It minimizes the travel time ,GHG emission, traffic accidents, fuel consumption.
The benefits of MRTS can be categorise like this:- • Requires 1/5th energy per passenger km compared to road-based
transport system. Causes less noise, no air pollution and eco friendly transport system
14. BUS RAPID TRANSIT SYSTEM
Typically, a BRT system includes roadways that are dedicated to buses, and gives priority to buses at intersections where
buses may interact with other traffic.
BRT aims to combine the capacity and speed of a metro with the claimed flexibility, lower cost and simplicity of a bus system
Main features
I. Dedicated lanes and alignment
II. Off-board fare collection
III. Intersection treatment
IV. Platform-level boarding
V. High capacity vehicles
VI. Quality stations
• Multiple doors to speed passenger boardings and enhance accessibility to disabled passengers
15. Light Rail Transits
Light rail transit (LRT) is a form of passenger urban rail transit characterized by a combination of tram and metro features.
While its rolling stock is more similar to a traditional tram, it operates at a higher capacity and speed, and often on an exclusive
right-of-way.
The term light rail was coined in 1972 by the U.S. Urban Mass Transportation Administration (UMTA; the precursor to the Federal
Transit Administration) to describe new streetcar transformations that were taking place in Europe and the United States.
Due to varying definitions, it is hard to distinguish between what is called light rail, and other forms of urban and commuter rail.
16. Metro Rail
A metro is a train that is specifically designed to run in metropolitan cities while local train are designed to connect the distances
within the city and its suburbs areas.
Metro rail is fast becoming the most popular means of mass rapid transit in India
A metro trains have separate track which is not shared with other trains
Kolkata Metro was the first metro in India.
Metro trains can be underground and elevated.
As of now around 10 Indian cities has the metro network.