This document outlines a study that aims to compare the effectiveness of clinical studies versus pharmacology trial studies in diagnosing Alzheimer's disease. It also seeks to determine if people under 65 with cardiovascular conditions are more likely to develop Alzheimer's. The proposed methodology involves two clinical study groups of 100 people aged 45-65 and four pharmacology trial groups of 25 people each, half with and half without cardiovascular histories. The study expects that trial studies will more efficiently diagnose Alzheimer's and that those with cardiovascular conditions will be more likely to develop early-onset Alzheimer's. The goals are to influence diagnosis methods and develop new early-intervention treatments.