Rheumatoid Arthritis - Muhammad Tahir Habib
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Rheumatoid Arthritis - Muhammad Tahir Habib
- 1. RHEUMATOID ARTHRITIS PRESENTED BY: MUHAMMAD TAHIR HABIB EMAIL: MRTAHIRHABIB@GMAIL.COM DEPARTMENT OF FOOD SCIENCE AND TECHNOLOGY UNIVERSITY OF AGRICULTURE, MULTAN Muhammad Tahir Habib Founder & CEO, TipRicks Inc. www.tipricks.tk Cell: +92 308 477 4257 Email: tipricks@gmail.com
- 2. Introduction Chronic autoimmune disease Causes joints to swell and can result pain, stiffness, and progressive loss of function. Affects pairs of joints (both hands, both feet, etc.) Permanent joint damage Cause deformity of the joints and loss of function. Patients face difficulty performing activities of daily living
- 3. Cont… Usually begins in middle age Disease ratio women to men is 3:1 Affect 1% of all population Effect other parts including the skin, lungs and eyes
- 4. Causes Cause is unknown Common in people who smoke and in people who are above a healthy weight. Possible causes include: Genetics Female Hormones Viruses or bacteria
- 5. Mechanism White blood cells move into the joint Joint Diagram
- 6. Cont.… Release certain chemicals called cytokines Attacked the lining of the joint.
- 7. Cont.… Thick tissue called Pannus grows inside
- 8. Cont… Tissue invades and destroys the cartilage Making it swell
- 9. Effects 40% of people may develop other conditions or disease. Patient likely to have Chest Pain Eyes Dry Mouth Difficult Breathing Bumpy Skin Weakness in the Knees Uneven stance in ankles
- 10. Symptoms Primary Symptoms Pain Stiffness Swelling of Joints Constitutional Symptoms Fever Malaise
- 11. Cont.… Weight loss Low-grade fever Fatigue
- 12. Diet Management No specific “diet” Researcher identified some food Citrus Fruits source of Vitamin C Whole grains higher in nutrients and fiber
- 13. Cont.… Peas and beans great source of protein contain antioxidants rich in folic acid, magnesium, iron, zinc and potassium Olive Oil contains a compound called oleocanthal acts like ibuprofen
- 14. Cont.… Fruits and Vegetables rich in antioxidants packed with vitamins and minerals lower C-reactive protein (CRP) Pomegranates Research is under way on POMx helpes lowering inflammation
- 15. Cont.… Onion Have antioxidants Reduce inflammation Reduce Heart risk Reduce LDL
- 16. Any Question ?
- 17. Thanks Everyone
- 18. Labelled Diagram of Joint Back to Mechanism
- 19. Proudly Supported By: TipRicks Inc. Ilm Gah All the content and design is copyrighted to the Owner and it may not be reproduce without permission!
Editor's Notes
- -Rheumatoid arthritis (RA) is a chronic autoimmune disease. -It causes joints to swell and can result in pain, stiffness, and progressive loss of function. -RA often affects pairs of joints (both hands, both feet, etc.) And can effect more than one joint including wrists and hands other joints can be affected such as shoulders, elbows, knees, feet, and ankles. -The inflammation of RA can cause permanent damage to the joints. -In severe cases, it can cause deformity of the joints and loss of function.
- -RA usually begins in middle age (80% cases occur between 30 and 55 years), but can start at any age. - - -Rheumatoid arthritis can also affect other parts of the body other than the joints including the skin, lungs and eyes. Many people have dry eyes and mouth (“sicca” symptoms or Sjogren’s syndrome) associated with the arthritis.
- No one knows exactly why some people develop rheumatoid arthritis. It is more common in people who smoke and in people who are above a healthy weight. Research has found that there are many possible causes, including: Genetics People with family members who have RA may be more likely to get it Hormones Female hormones may play a role in the disease Viruses or bacteria RA may be related to viruses or bacteria that you come in contact with during your life
- The white blood cells move into the joint
- they release chemicals called cytokines which attacked the lining of the joint called synovial membrane
- thick tissue called pannus grows inside the joint
- -Over time that tissue invades and destroys the cartilage and bone inside the joint. -Inflammation causes fluid buildup in the joint making it swell. Eventually the damage makes it hard to move the joint.
- Up to 40% of people with RA may develop other conditions during the course of their disease. While RA affects the joints, people with RA may also be more likely to have the following conditions: Chest Pain You may develop chest pain if your lungs get damaged from log term inflammation. Dry Eyes RA can cause extremely dry eyes, that can further cause eye infection. Dry Mouth Chronic dry mouth can make I hard to eat and swallow. It can also lead to other disease (like gum disease) and mouth infection. Difficulty Breathing The inflammation of RA can spread to lungs making it hard to breathe. Patient can also experience coughing. Bumpy Skin Hardened skin bumps called nodules may form on your arms especially around the elbows Weakness in the Knees RA can cause notable stiffness and swelling in your knees. The pain is usually worse in the morning and after standing up. Uneven stance in ankles When RA effects your ankles you may notice that its more difficult to walk evenly. Standing for long periods of time may also be very painful.
- -Constitutional Symptoms (Constitutional symptoms refers to a group of symptoms that can affect many different systems of the body. Examples include weight loss, fevers, headache etc.) -Malaise (a general feeling of discomfort, illness, or unease whose exact cause is difficult to identify.)
- While there is no specific “diet” that people with rheumatoid arthritis (RA), should follow, researchers have identified certain foods that can help control inflammation.` Citrus Fruits Oranges, grapefruits, and limes are great sources of vitamin C, which leads to a strong immune system that can help hold off inflammatory diseases like RA. Whole grains Oats, whole wheat, brown rice, quinoa and other whole grains may lower levels of CRP and reduce the risk of heart disease, which is elevated in people with RA. Whole grains are higher in nutrients and fiber than refined grains.
- Peas and beans These legumes are a great source of protein, which is important for muscle health – and people with RA are prone to muscle loss. What’s more, peas and beans are practically fat free, contain antioxidants, and some are rich in folic acid, magnesium, iron, zinc and potassium, all known for their heart and immune system benefits. Olive Oil Use olive oil instead of other oils and fats. In addition to healthy monounsaturated fat, it contains a compound called oleocanthal (natural phenolic compound found in olive oil) that reduces inflammation and acts like ibuprofen in alleviating pain. But eat it in moderation; as with all oils, it’s a fat that can lead to weight gain.
- Fruits and Vegetables Fruits and vegetables are rich in antioxidants, which help stabilize molecules called free radicals that can trigger inflammation and damage cells. They’re also packed with vitamins and minerals the body needs and in polyphenols, all of which may help lower C-reactive protein (CRP), a marker of inflammation. To get the greatest health benefits, eat several types of fresh or frozen fruits each day, but watch out for sugar content in frozen options. Eat a colorful variety of veggies to get the most nutrients. Pomegranates Research is under way on a pomegranate extract called POMx (powerful blend of all-natural polyphenol antioxidants made from the very same pomegranates). It helped lower inflammation and lessen joint damage in mice, but it needs more testing in humans.
- Onion Onions are packed with beneficial antioxidants. They may also reduce inflammation, heart disease risk and LDL, or “bad” cholesterol. Try them sautéed, grilled or raw in salads, stir-fries, whole-wheat pasta dishes or sandwiches.