This document provides an introduction to the fifth edition of the textbook "Introduction to Management Science: A Modeling and Case Studies Approach with Spreadsheets" by Frederick S. Hillier and Mark S. Hillier. The textbook uses a case studies approach and spreadsheets to teach management science. It aims to present the material in a way that focuses on business situations and model formulation rather than algorithms. The fifth edition builds on the strengths of previous editions and incorporates user feedback to enhance the quality of the instruction.