This short document provides answers to questions from OŠ Ivana Cankarja Trbovlje school in Slovenia. It thanks the school for participating in a survey and states that posters will be mailed to the school at the end of an unspecified project.
This study investigated the association between a single nucleotide polymorphism (G-29A) in the promoter region of the follicle-stimulating hormone receptor (FSHR) gene and FSHR expression levels in granulosa cells. The researchers found that 72% of subjects with the AA genotype were poor ovarian responders to FSH stimulation during in vitro fertilization treatment. Subjects with the AA genotype also had significantly reduced FSHR mRNA and protein expression in granulosa cells compared to those with the GG genotype. This suggests that poor ovarian response in subjects with the AA genotype is due to reduced FSHR expression at both the transcriptional and translational levels.
The document summarizes a study that analyzed the association between allelic combinations of two polymorphisms in the FSH receptor (FSHR) gene and ovarian response in women undergoing in vitro fertilization (IVF). The polymorphisms located at positions -29 and 680 of the FSHR gene were genotyped. The combinations of these polymorphisms formed nine discrete genotypes. Clinical data from 150 IVF subjects was analyzed based on genotype. Results showed that 75% of subjects with the A/A–Asn/Asn genotype were poor ovarian responders, with an odds ratio of 7.92. This genotype also had significantly lower FSHR mRNA expression in granulosa cells compared to other genotypes. The study
This document summarizes research on mutations and polymorphisms in the FSH receptor gene and their functional implications in human reproduction. It discusses both inactivating and activating mutations that have been identified in the FSH receptor gene in individuals with infertility or other reproductive issues. Inactivating mutations are associated with conditions like ovarian dysgenesis and impaired spermatogenesis, while activating mutations have been found in cases of ovarian hyperstimulation syndrome. Studies on the effects of these genetic variants provide insights into the molecular mechanisms of FSH receptor function and FSH-receptor interactions. The document also reviews research on polymorphisms in the FSH receptor gene and their potential role in predicting treatment response to FSH therapy.
Hultin Partners is a boutique management consulting firm Specialized in creating profitable internationalization strategies and solutions for enterprises, business development organizations and
public sector clients heading to the European and Russian markets.
This study characterized two naturally occurring mutations (Val514Ala and Ala575Val) in the follicle stimulating hormone receptor (FSHR) gene identified in women with different phenotypes. The Val514Ala mutation was found in a woman with ovarian hyperstimulation syndrome (OHSS) during in vitro fertilization (IVF) treatment. Functional studies showed this mutant receptor had increased cell surface expression and higher signaling activity at lower FSH doses compared to the wild type receptor. The Ala575Val mutation was identified in a woman with primary amenorrhea. This mutant receptor displayed lower cell surface expression and did not show a dose-dependent increase in cAMP accumulation like the wild type receptor. The functional effects of the mutations help explain
Application of Distributed processing and Big data in agricultural DSSAnusha Basavaraj
This document outlines a presentation on the Big Weather solution, an agricultural decision support system that utilizes big data and distributed processing. It discusses key concepts like decision support systems, big data, Hadoop, and cloud computing. The Big Weather system architecture is described as having three main modules: a web portal, data server, and Hadoop cluster. Test results showed improved job processing times when increasing the number of virtual machines in the Hadoop cluster. The presentation concludes that the Big Weather solution can help farmers improve productivity based on climate data.
This study investigated the association between a single nucleotide polymorphism (G-29A) in the promoter region of the follicle-stimulating hormone receptor (FSHR) gene and FSHR expression levels in granulosa cells. The researchers found that 72% of subjects with the AA genotype were poor ovarian responders to FSH stimulation during in vitro fertilization treatment. Subjects with the AA genotype also had significantly reduced FSHR mRNA and protein expression in granulosa cells compared to those with the GG genotype. This suggests that poor ovarian response in subjects with the AA genotype is due to reduced FSHR expression at both the transcriptional and translational levels.
The document summarizes a study that analyzed the association between allelic combinations of two polymorphisms in the FSH receptor (FSHR) gene and ovarian response in women undergoing in vitro fertilization (IVF). The polymorphisms located at positions -29 and 680 of the FSHR gene were genotyped. The combinations of these polymorphisms formed nine discrete genotypes. Clinical data from 150 IVF subjects was analyzed based on genotype. Results showed that 75% of subjects with the A/A–Asn/Asn genotype were poor ovarian responders, with an odds ratio of 7.92. This genotype also had significantly lower FSHR mRNA expression in granulosa cells compared to other genotypes. The study
This document summarizes research on mutations and polymorphisms in the FSH receptor gene and their functional implications in human reproduction. It discusses both inactivating and activating mutations that have been identified in the FSH receptor gene in individuals with infertility or other reproductive issues. Inactivating mutations are associated with conditions like ovarian dysgenesis and impaired spermatogenesis, while activating mutations have been found in cases of ovarian hyperstimulation syndrome. Studies on the effects of these genetic variants provide insights into the molecular mechanisms of FSH receptor function and FSH-receptor interactions. The document also reviews research on polymorphisms in the FSH receptor gene and their potential role in predicting treatment response to FSH therapy.
Hultin Partners is a boutique management consulting firm Specialized in creating profitable internationalization strategies and solutions for enterprises, business development organizations and
public sector clients heading to the European and Russian markets.
This study characterized two naturally occurring mutations (Val514Ala and Ala575Val) in the follicle stimulating hormone receptor (FSHR) gene identified in women with different phenotypes. The Val514Ala mutation was found in a woman with ovarian hyperstimulation syndrome (OHSS) during in vitro fertilization (IVF) treatment. Functional studies showed this mutant receptor had increased cell surface expression and higher signaling activity at lower FSH doses compared to the wild type receptor. The Ala575Val mutation was identified in a woman with primary amenorrhea. This mutant receptor displayed lower cell surface expression and did not show a dose-dependent increase in cAMP accumulation like the wild type receptor. The functional effects of the mutations help explain
Application of Distributed processing and Big data in agricultural DSSAnusha Basavaraj
This document outlines a presentation on the Big Weather solution, an agricultural decision support system that utilizes big data and distributed processing. It discusses key concepts like decision support systems, big data, Hadoop, and cloud computing. The Big Weather system architecture is described as having three main modules: a web portal, data server, and Hadoop cluster. Test results showed improved job processing times when increasing the number of virtual machines in the Hadoop cluster. The presentation concludes that the Big Weather solution can help farmers improve productivity based on climate data.
Summer Training at Indira Gandhi Super Thermal Power Project (IGSTPP)Nadeem Khilji
Aravali Power Company Pvt Ltd. (APCPL) is a Joint venture company with 50% share of NTPC Ltd, 25% of Haryana Power Generation Company Ltd (HPGCL, Haryana State company), and 25% of Indraprastha Power Generation Company Ltd (IPGCL, DelhiState company). The company was registered on 21st Dec 2006.
APCPL has constructed a coal based power plant near Village Jharli, District- Jhajjar (Haryana) named Indira Gandhi Super Thermal Power Project (IGSTPP). Presently under Stage-I, power plant of 3x 500MW capacity is constructed, whose all 3 units are commissioned. There is a future provision of 2x 660 MW under Stage-II.
High Voltage Direct Current Transmission SystemNadeem Khilji
The development of HVDC (High Voltage Direct Current) transmission system dates back to the 1930s when mercury arc rectifiers were invented. Since the 1960s, HVDC transmission system is now a mature technology and has played a vital part in both long distance transmission and in the interconnection of systems. Transmitting power at high voltage and in DC form instead of AC is a new technology proven to be economic and simple in operation which is HVDC transmission. HVDC transmission systems, when installed, often form the backbone of an electric power system. They combine high reliability with a long useful life. An HVDC link avoids some of the disadvantages and limitations of AC transmission. HVDC transmission refers to that the AC power generated at a power plant is transformed into DC power before its transmission. At the inverter (receiving side), it is then transformed back into its original AC power and then supplied to each household. Such power transmission method makes it possible to transmit electric power in an economic way.
The document summarizes various waste water treatment processes. It discusses primary treatment which involves removing large solids through screens and sedimentation. Secondary treatment uses biological processes like trickling filters, activated sludge tanks, and lagoons to break down organic matter. Anaerobic digesters are also used. Finally, disinfection through chlorination, UV, or ozonation is discussed to remove pathogens before effluent is discharged or reused.
Disorders due to macro and micro nutrients deficiencyBhawna Kargeti
This document discusses macro and micronutrients and deficiency diseases. It provides details on:
- Vitamins (A, B, C, D, E, K) and common deficiency diseases
- Minerals (calcium, iron, iodine, zinc, magnesium, potassium, chromium, sodium) and related diseases
- Carbohydrates and effects of deficiency
- Types of fats (saturated, unsaturated, trans) and fat-related diseases like atherosclerosis and heart disease
- Proteins and protein deficiency diseases like marasmus and kwashiorkor
It is an informative overview of nutrients, food sources, and health impacts of deficiencies.
The document defines key terms related to food safety standards and regulations in India. It provides definitions for terms like "food" according to the Food Safety and Standards Act. It outlines the objectives and importance of having food safety standards to protect consumers and ensure confidence in the food system. It introduces the Food Safety and Standards Authority of India (FSSAI), which was established in 2006 to regulate food safety and set science-based standards in India. FSSAI's duties include framing rules, enforcing quality control, providing scientific advice and capacity building on food safety issues.
Summer Training at Indira Gandhi Super Thermal Power Project (IGSTPP)Nadeem Khilji
Aravali Power Company Pvt Ltd. (APCPL) is a Joint venture company with 50% share of NTPC Ltd, 25% of Haryana Power Generation Company Ltd (HPGCL, Haryana State company), and 25% of Indraprastha Power Generation Company Ltd (IPGCL, DelhiState company). The company was registered on 21st Dec 2006.
APCPL has constructed a coal based power plant near Village Jharli, District- Jhajjar (Haryana) named Indira Gandhi Super Thermal Power Project (IGSTPP). Presently under Stage-I, power plant of 3x 500MW capacity is constructed, whose all 3 units are commissioned. There is a future provision of 2x 660 MW under Stage-II.
High Voltage Direct Current Transmission SystemNadeem Khilji
The development of HVDC (High Voltage Direct Current) transmission system dates back to the 1930s when mercury arc rectifiers were invented. Since the 1960s, HVDC transmission system is now a mature technology and has played a vital part in both long distance transmission and in the interconnection of systems. Transmitting power at high voltage and in DC form instead of AC is a new technology proven to be economic and simple in operation which is HVDC transmission. HVDC transmission systems, when installed, often form the backbone of an electric power system. They combine high reliability with a long useful life. An HVDC link avoids some of the disadvantages and limitations of AC transmission. HVDC transmission refers to that the AC power generated at a power plant is transformed into DC power before its transmission. At the inverter (receiving side), it is then transformed back into its original AC power and then supplied to each household. Such power transmission method makes it possible to transmit electric power in an economic way.
The document summarizes various waste water treatment processes. It discusses primary treatment which involves removing large solids through screens and sedimentation. Secondary treatment uses biological processes like trickling filters, activated sludge tanks, and lagoons to break down organic matter. Anaerobic digesters are also used. Finally, disinfection through chlorination, UV, or ozonation is discussed to remove pathogens before effluent is discharged or reused.
Disorders due to macro and micro nutrients deficiencyBhawna Kargeti
This document discusses macro and micronutrients and deficiency diseases. It provides details on:
- Vitamins (A, B, C, D, E, K) and common deficiency diseases
- Minerals (calcium, iron, iodine, zinc, magnesium, potassium, chromium, sodium) and related diseases
- Carbohydrates and effects of deficiency
- Types of fats (saturated, unsaturated, trans) and fat-related diseases like atherosclerosis and heart disease
- Proteins and protein deficiency diseases like marasmus and kwashiorkor
It is an informative overview of nutrients, food sources, and health impacts of deficiencies.
The document defines key terms related to food safety standards and regulations in India. It provides definitions for terms like "food" according to the Food Safety and Standards Act. It outlines the objectives and importance of having food safety standards to protect consumers and ensure confidence in the food system. It introduces the Food Safety and Standards Authority of India (FSSAI), which was established in 2006 to regulate food safety and set science-based standards in India. FSSAI's duties include framing rules, enforcing quality control, providing scientific advice and capacity building on food safety issues.
How to Setup Warehouse & Location in Odoo 17 InventoryCeline George
In this slide, we'll explore how to set up warehouses and locations in Odoo 17 Inventory. This will help us manage our stock effectively, track inventory levels, and streamline warehouse operations.
A review of the growth of the Israel Genealogy Research Association Database Collection for the last 12 months. Our collection is now passed the 3 million mark and still growing. See which archives have contributed the most. See the different types of records we have, and which years have had records added. You can also see what we have for the future.
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Main Java[All of the Base Concepts}.docxadhitya5119
This is part 1 of my Java Learning Journey. This Contains Custom methods, classes, constructors, packages, multithreading , try- catch block, finally block and more.
How to Manage Your Lost Opportunities in Odoo 17 CRMCeline George
Odoo 17 CRM allows us to track why we lose sales opportunities with "Lost Reasons." This helps analyze our sales process and identify areas for improvement. Here's how to configure lost reasons in Odoo 17 CRM
How to Make a Field Mandatory in Odoo 17Celine George
In Odoo, making a field required can be done through both Python code and XML views. When you set the required attribute to True in Python code, it makes the field required across all views where it's used. Conversely, when you set the required attribute in XML views, it makes the field required only in the context of that particular view.
How to Add Chatter in the odoo 17 ERP ModuleCeline George
In Odoo, the chatter is like a chat tool that helps you work together on records. You can leave notes and track things, making it easier to talk with your team and partners. Inside chatter, all communication history, activity, and changes will be displayed.
Walmart Business+ and Spark Good for Nonprofits.pdfTechSoup
"Learn about all the ways Walmart supports nonprofit organizations.
You will hear from Liz Willett, the Head of Nonprofits, and hear about what Walmart is doing to help nonprofits, including Walmart Business and Spark Good. Walmart Business+ is a new offer for nonprofits that offers discounts and also streamlines nonprofits order and expense tracking, saving time and money.
The webinar may also give some examples on how nonprofits can best leverage Walmart Business+.
The event will cover the following::
Walmart Business + (https://business.walmart.com/plus) is a new shopping experience for nonprofits, schools, and local business customers that connects an exclusive online shopping experience to stores. Benefits include free delivery and shipping, a 'Spend Analytics” feature, special discounts, deals and tax-exempt shopping.
Special TechSoup offer for a free 180 days membership, and up to $150 in discounts on eligible orders.
Spark Good (walmart.com/sparkgood) is a charitable platform that enables nonprofits to receive donations directly from customers and associates.
Answers about how you can do more with Walmart!"