This document provides an overview of the regional repertory "Repertory to the symptoms of rheumatism, sciatica etc" by Alfred Pulford. It discusses the author, contents, organization, merits and demerits of the book. The repertory contains 211 pages organized into 29 chapters based on anatomical regions. It provides concise rubrics for rheumatism symptoms and includes accompanying general symptoms. While specific to rheumatism, it serves as a quick reference for practitioners.
ANALYTICAL REPERTORY OF THE SYMPTOMS OF THE MIND
Dr. Smita Brahmachari
The practice of Homoeopathy is a balancing act. We weigh pros and cons to arrive at a prescription; for us differential diagnosis is not only for identifying the disease but also for identifying the drug. In such identification process we gather all the symptoms of the patient, without a prejudiced eye. We do not judge the patient or censor his sayings for we very well know the importance of each and every symptoms – whether it is a mental or a physical symptom. Mental symptoms were used for the final deciding vote rather than for initial identification of medicines, except in a few exceptional cases. Pioneer homoeopaths had this approach to practice that the Mind and Body are not separate but are only different manifestations of the same vital force.
The need for such a repertory where the mental concomitants of physical complaints and physical concomitants of mental states are available has been met in Dr.C.Hering’s ANALYTICAL REPERTORY OF THE SYMPTOMS OF THE MIND. This book contains those symptoms of the mind that have been observed in connection with the bodily symptoms. This book is not a collection of mental symptoms as in Synthetic Repertory, Vol-I. Hering being an ardent follower of Hahnemann wanted to revive Hahnemannian concept back into Homoeopathic practice. So, at the end of the ‘Introduction’, he says that through this work, the future Homoeopaths will be able to follow the right way of the true Hahnemannian school, i.e. always to individualize.
This is a humble attempt on my part to represent this work of Hering. I have used this book in the OPD only a few times but after going through the whole work, the potentiality of this book can definitely be felt. We all must try to use this book and establish the role it can play in our daily practice.
ANALYTICAL REPERTORY OF THE SYMPTOMS OF THE MIND
Dr. Smita Brahmachari
The practice of Homoeopathy is a balancing act. We weigh pros and cons to arrive at a prescription; for us differential diagnosis is not only for identifying the disease but also for identifying the drug. In such identification process we gather all the symptoms of the patient, without a prejudiced eye. We do not judge the patient or censor his sayings for we very well know the importance of each and every symptoms – whether it is a mental or a physical symptom. Mental symptoms were used for the final deciding vote rather than for initial identification of medicines, except in a few exceptional cases. Pioneer homoeopaths had this approach to practice that the Mind and Body are not separate but are only different manifestations of the same vital force.
The need for such a repertory where the mental concomitants of physical complaints and physical concomitants of mental states are available has been met in Dr.C.Hering’s ANALYTICAL REPERTORY OF THE SYMPTOMS OF THE MIND. This book contains those symptoms of the mind that have been observed in connection with the bodily symptoms. This book is not a collection of mental symptoms as in Synthetic Repertory, Vol-I. Hering being an ardent follower of Hahnemann wanted to revive Hahnemannian concept back into Homoeopathic practice. So, at the end of the ‘Introduction’, he says that through this work, the future Homoeopaths will be able to follow the right way of the true Hahnemannian school, i.e. always to individualize.
This is a humble attempt on my part to represent this work of Hering. I have used this book in the OPD only a few times but after going through the whole work, the potentiality of this book can definitely be felt. We all must try to use this book and establish the role it can play in our daily practice.
Introduction to the concordance repertoriesdrmohitmathur
The presentation discusses the fundamental concept of concordance repertories. The framework, merits and demerits of Gentry concordance repertory and Repertory of Hering’s Guiding Symptoms of our Materia Medica by Calvin B.Knerr are described in detail.
Dr.J.T. KENT REPERTORY(COMPLETE INFORMATION )HOMEOPATHY
hello, in this PPT we have discussed about Dr.J.T.KENT REPERTORY.
VISIT MY CHANNEL FOR COMPLETE INFORMATION OF KENT REPERTORY
LINK --- https://www.youtube.com/watch?v=nFH5js7RQ30&ab_channel=Dr.PriyankaSaini
TOPIS THAT WE WILL COVER IN THIS VEDIO:
HISTORY OF KENT REPERTORY
PHILOSOPHICAL REPERTORY
PLAN AND CONSTRUCTION
ARRANGEMENTS OF RUBRICS
SPECIAL FEATURES OF KENT REPERTORY
“DON’T TAKE THIS MAGICAL THING SO CALLED- LIFE FOR GRANTED
GO HUNT YOUR DREAMS, LIVE YOUR LEGACY”
~ Dr.Priyanka Saini ~
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Dr.Priyanka Saini
“The Pessimist Sees Difficulty In Every Opportunity. The Optimist Sees Opportunity In Every Difficulty.”
#homeopathy
#kent
#repertory
#jtkent
A SYNOPTIC KEY OF THE MATERIA MEDICA
Dr. Smita Brahmachari
Correct prescribing is the art of carefully fitting pathogenetic to clinical symptoms, and such at present requires a special aptness in grasping the essential points of symptom images, great drudgery, mastering a working knowledge of our large materia medica and a most skillful use of many books of reference. It is the aim of this book “A Synoptic Key of the Materia Medica” is to simplify and introduce method into this work, so that the truly homoeopathic curative remedy may be worked out with greater ease and certainty.
Introduction to the concordance repertoriesdrmohitmathur
The presentation discusses the fundamental concept of concordance repertories. The framework, merits and demerits of Gentry concordance repertory and Repertory of Hering’s Guiding Symptoms of our Materia Medica by Calvin B.Knerr are described in detail.
Dr.J.T. KENT REPERTORY(COMPLETE INFORMATION )HOMEOPATHY
hello, in this PPT we have discussed about Dr.J.T.KENT REPERTORY.
VISIT MY CHANNEL FOR COMPLETE INFORMATION OF KENT REPERTORY
LINK --- https://www.youtube.com/watch?v=nFH5js7RQ30&ab_channel=Dr.PriyankaSaini
TOPIS THAT WE WILL COVER IN THIS VEDIO:
HISTORY OF KENT REPERTORY
PHILOSOPHICAL REPERTORY
PLAN AND CONSTRUCTION
ARRANGEMENTS OF RUBRICS
SPECIAL FEATURES OF KENT REPERTORY
“DON’T TAKE THIS MAGICAL THING SO CALLED- LIFE FOR GRANTED
GO HUNT YOUR DREAMS, LIVE YOUR LEGACY”
~ Dr.Priyanka Saini ~
Subscribe to receive weekly VIDEOS of hope, encouragement, and inspiration from Dr. Priyanka
Follow #drPriyanka on social media
FACEBOOK- https://www.facebook.com/Noarikifukat...
INSTGRAM- https://www.instagram.com/__nirvikalp...
BLOGSPOT- https://drpriyankasaini.blogspot.com/
TWITTER- https://twitter.com/drpriyankasaini
LINKEDIN- https://www.linkedin.com/in/dr-priyan...
Thank you for your generosity!
Dr.Priyanka Saini
“The Pessimist Sees Difficulty In Every Opportunity. The Optimist Sees Opportunity In Every Difficulty.”
#homeopathy
#kent
#repertory
#jtkent
A SYNOPTIC KEY OF THE MATERIA MEDICA
Dr. Smita Brahmachari
Correct prescribing is the art of carefully fitting pathogenetic to clinical symptoms, and such at present requires a special aptness in grasping the essential points of symptom images, great drudgery, mastering a working knowledge of our large materia medica and a most skillful use of many books of reference. It is the aim of this book “A Synoptic Key of the Materia Medica” is to simplify and introduce method into this work, so that the truly homoeopathic curative remedy may be worked out with greater ease and certainty.
A Record of the Positive effects of drugs upon the healthy human organism.
Twelve volumes comprise one of homeopathys most comprehensive materia medica. References include the actual prover or clinical experience.
This is a record of most of the homeopathic drug proving and toxicology up to this point.The volumes were published between 1874 and 1879.
Medical TerminologyBasic Word Structure Cha.docxbuffydtesurina
Medical Terminology
Basic Word Structure
Chapter One.
Chapter objectives
To divide medical terms into component parts.
To analyze, pronounce, and spell medical terms using common combining forms, suffixes, and prefixes.
2
Medical Language
You decided to pursue a career in the health care field and you will know so many new sights and sounds, also you want to embrace the medical culture and become part of it.
Your first attempts at interacting with other healthcare professionals are successful because you know medical language.
Immediately, you are immersed in interesting medical activities and important conversations, and you understand what is going on.
Your future in the healthcare is certain because you took the time to study medical language.
Medical language is the language of the healthcare profession, and medical words are the tools of the trade!
Learning medical language is your key to a successful career in the healthcare field.
Medical Language and communication.
Communication in any language consists of five language skills. You need to master all five skills in order to communicate on the job with other healthcare professional.
Reading
Listening
Thinking, analyzing, and understanding.
Writing (or typing) and spelling
Speaking and pronouncing.
- These skills are critical in the communication of medical language, and you will develop all five skills by given you many opportunities to practice until you have mastered all of them.
Word Analysis
If you work in a medical setting, you use medical words every day.
In addition, you hear medical terms spoken in your doctor’s office, read about health issues, and make daily decisions about your own health care and the health care of your family.
Terms such as: arthritis, electrocardiogram, hepatitis, and anemia describe conditions and tests that are familiar.
Other medical words are more complicated, but as you work in this course, you will begin to understand them even if you have never studied biology or science.
Medical words are like individual jigsaw puzzles. Once you divide the terms into their components and learns the meaning of the individual parts, you can use that knowledge to understand many other new terms.
For example, the term HEMATOLOGY is divide into three parts:
HEMAT/O/LOGY
Root
(Blood)
Combining
vowel
Suffix
(study of)
Hematology
When you analyze a medical term, begin at the END of the word. The ending is called a SUFFIX.
All Medical terms contain suffixes. The suffix in Hematology is –LOGY, which means study of.
Next, look at the beginning of the term. HEMAT- is the word root. The root gives the essential meaning of the term. The root HEMAT- means blood.
The third part of this term, which is the letter 0, has no meaning of its own but is an important connector between the root (HEMA-) and the suffix (-LOGY). It is called a combining vowel.
The lett.
AN 1.1 introduction anatomical terminology-Dr.GosaiDr.B.B. Gosai
This is first lecture in anatomy regarding anatomical terminology to familiarize students for Anatomical position, various branches of anatomy, Planes, Terms of relations and terms of movements.
Visit my website for more presentations: https://www.drbbgosai.com/
Dyspnea derives from Greek for “ “ shortness of breath hard breathing ”. It is often also described as ”. This is a subjective sensation of breathing, from mild discomfort to feelings of suffocation. It is a sign of a variety of disorders and is primarily an indication of ventilation or of inadequate insufficient amounts of oxygen in the circulating blood .
Dyspnea happens when a “mismatch” occurs between afferent and efferent signaling. As the brain receives afferent ventilation information, it is able to compare it to the current level of respiration by the efferent signals. If the level of respiration is inappropriate for the body’s status and need, then dyspnea might occur
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NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
2. PLAN OF PRESENTATION:
Introduction to Regional repertories
About author
Contents of the book
Plan and construction
Merits and demerits
Conclusion
3. What is REGIONAL REPERTORy?
Regional repertories are defined as
repertories containing rubrics (symptoms)
related to particular organ/ part or system
like respiratory system, excretory system.
They are repertories where only rubrics
related to some clinical condition or system
are grouped together.
5. INTRODUCTION
What is Rheumatism???
Rheumatism is any of the various conditions
characterized by inflammation or pain in muscles, joints,
or fibrous tissue.
Defined as Any of a variety of disorders marked by
inflammation , degeneration, or metabolic derangement
of the connective tissue structures especially the joints
and related structures and attended by pain, stiffness, or
limitation of motion
6. published by Krammes Tiffin, Ohio in 1898.
It is one of the valuable regional repertory in this
subject
This book consist of 211 pages.
7. ABOUT AUTHOR
Alfred Pulford, MD was born in Bradford city in England in
1863 (1863 – 1948).
graduated from Cleveland homoeopathic medical college
in the year 1885.
He was a prolific writer. He has written 100 articles in
journals like homoeopathic recorder and IHA transactions.
Joined IHA in 1924, practiced with his son in Toledo, ohio
8. CONTRIBUTIONS OF AUHTOR:
His other famous works are
-Homoeopathic Leaders in Pneumonia
-Homoeopathy Materia Medica of Graphic Drug Pictures
-Repertory of the Symptoms of Rheumatism, Sciatica Etc.
9. CONTENTS OF THE BOOK
“ All forms of substance are but gases in
various stages of density; divine power
being invisible, lays latent in all objects
organic or inorganic hence, the triumph of
homoeopathic medication” – DR. Alfred
pulford.
10. PREFACE
The author says that Rheumatism is one of the prevalent
disease that was neglected by the profession he feels a
need to compile a repertory for rheumatism and sciatica.
Rheumatism, while a very prevalent disease, seems to
me to have been a very much neglected subject as far as
works go.
11. INTRODUCTION
Dr. Pulford writes in compiling this repertory the
objective has been to arrange and classify groups
and conditions of symptoms in such a manner that
they may be readily available
Regarding abbreviations and arrangement of
remedies
The crescendo and diminuendo marks express the
aggravations and amelioration
stated the more important only
13. Small of back
Lumbar region
Sacral region
Coccygeal region
Lower extremities
Hips
Thighs
Knees
Legs
Ankles
Feet
Toes
General symptoms
Accompanying
symptoms
Regional index
14. ARRANGEMENT OF THE REPERTORY
29 chapters in arranged in anatomical schema
After introduction aggravation and amelioration
chapters which contains general modifying factors,
afterwards the chapters are arranged in Anatomical
Hahnemanian Schema
Rubrics are arranged in alphabetical
arrangement.Rubrics are represented in capital bold
roman and sub rubrics are in normal roman with
indentation
15. TYPOGRAPHY:
Three types of typography were used in this repertory but their relative
values not discussed anywhere
1. BOLD CAPITALS
2. Italics
3. Ordinary roman
16. In aggravation chapter in many rubrics author gave opposite modifying factors by
wordings “Reverse “
For ex:
Cold air: cist.,rhus., Reverse:puls
Eating warm food:phos., Reverse:puls
Limb hanging down:calc., Reverse:verat
Lying on affected side:bry.,kali.iod,silicia,tell., Reverse:puls
Riding in carriage:coccul,nux.mos,petr., Reverse:graph,nit.acid
Different types of pain rubrics are present in alphabetically ,and also in the rubric pain
17. Different particular modifying factors are represented in the
particular chapters in the particular rubrics
Ex: in shoulder and arms chapter
Dislocated and broken feeling >violent motion Niccol
In upper limbs chapter
Bones paralysing, tearing in jerking< touch:china
In forearms chapter
Pain excruciating, radius<motion or touch :Sabina
18. In many chapters first letter of the part were used to represent
the part in short to denote the part in rubrics
Ex; in back chapter
Dull B: ache:caul
Chills in B: gels
In spine cord and vertebrae chapter
Carries of lumbar.V: phos.ac.
Coldness along V.column: acon
Plug feeling of a in S: anac
19. In many chapters side also represented in short form R-right side
and L –left side
In lower extremities
Sciatica L. side part cold<evening to midnight: puls
In hips chapters
Drawing ,in joint L: acon,rhust,sep
In knees chapter
Rheumatism ,esp R:>motion<boring,nights knee
swollen;kali.c
Clinical rubrics like pots disease, rickets, rheumatism, sciatica,
anaemia, e.t.c were present
20. Numerous cross references are present they are two types cross reference without
remedies
Ex :in fingers chapter
Toes: see spread
Whitlow:see felon
In spine cord and vertebrae chapter
Abdomen:see pain cutting
In chapter scapular region
Lung;see aching between
Neck;see pain rheumatic
21. Cross references with medicines..
Ex: in shoulders and arms chapter
Tearing;ambr,bry,kali.c,lyco,,mez,phos,puls,stan,zinc
See pain tearing
In upper extremities chapter
Paralytic jerking,teraing in bones:china
See pain,paraytic
In forearms chapter
Drawing;hepar,olean,sulph
See also pain drawing
In back chapter
Knees,drawn up,lies on back:merc.corr
See also weakness back
22. ACCOMPANYING SYMPTOMS
In this section the author illustrated the accompanying
changes in the other parts of the body and along with
the rheumatological manifestations. these will be
represented in the following sub sections..
Mind, Vertigo,Scalp,Head,Eyes,Ear,Nose ,Face,Mouth,
Throat,Appetite And Thirst,Stomach, Abdomen,
Anus,Rectum And Stool,Urine,Chest,Heart,Sleep And
Dreams ,Chill,Heat And Sweat,Skin
in every sub sections rubrics are arranged in the
alphabetical order
23. REGIONAL INDEX
in this section the author indexing the anatomical parts alphabetically
with respective page numbers. There are 52 chapters starting with
Abdomen
Aggravations
Ameliorations
Ankles
Anus
Appetite
Arms
Back
29. ERRATA:
Under this section the errors in the book were represented along with the
page numbers and corrections as well
30. MERITS:
Very useful specific work for rheumatological problems and
sciatica
Gradation of remedies were present
accompanying general changes are also discussed in accompanying
symptoms section
errors and its corrections also given in the last chapter errata
very useful for quick reference in rheumatological and sciatica
cases
some clinical rubrics like pots disease, rickets, rheumatism,
sciatica, anaemia also present under many chapters
very useful as a reference work for rheumatological cases
31. DEMERITS:
Not useful for systematic repertorization
Number of rubrics are very less in the chapters
Gradations of remedies present but relative value is not
discussed any where
No index of remedies.
No working method.
32. CONCLUSION
In all cases physician cannot get all the data for
selection of the similimum. This work is useful for
cases with paucity of symptoms and where mentals
are lacking. This small special book is complete in
its construction and arrangement it is very useful as
ready reference book to use at bedside cases
33. BIBLIOGRAPHY:
1.ALFRED PULFORD Repertory of the symptoms of rheumatism,
sciatica etc .
2.DR.VIDYADHAR R.KHANAJ Reperire
3.Dr.K.HARINADHAM The Principles and Practice of Repertorisation
WEBSITE:
4.https://www.homeobook.com/pioneers-of-homeopathy-
powerpoint-presentations/
5.https://www.merriam-webster.com/dictionary/rheumatism
6. https://www.who.int/chp/topics/rheumatic/en/
7.www.homoeobook.com/repertorytotherheumaticremedies
/amp/?amp-js-v+a2