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© 2019, IJMS. All Rights Reserved 12
Available Online at www.ijms.co.in
Innovative Journal of Medical Sciences 2019; 3(3):12-14
ISSN 2581 – 4346
RESEARCH ARTICLE
Realization of students about origin, signs, consequences, and remedy of bacterial
disease syphilis
Muhammad Imran Qadir, Urooj Fatima*
Department of Biology, Institute of Molecular Biology and Biotechnology, Bahauddin Zakariya University,
Multan, Pakistan
Received on: 05 April 2019; Revised on: 10 May 2019; Accepted on: 10 June 2019
ABSTRACT
Introduction: The questionnaire was produced to generate perception among students about causes, signs,
and remedy of bacterial disease syphilis. Material and Method: About 78 subjects were participated in
this study. They all are students of Bahauddin Zakariya University, Multan. I went to them and asked them
the few questions about syphilis disease. Result: These questions were prepared to inform the students.
The basic goal of this study was to create acknowledgment among students. Conclusion: From this study,
I have concluded that most of people were unaware of this disease. They did not know about it.
Keywords: Syphilis, Treponema, Congenital
INTRODUCTION
Syphilis is a bacterial disease that is caused by
the bacteria Treponema pallidum. It can be treated
in early stages. Without treatment, it can lead to
fatal disorders such as neurological disorders
and death. It is highly contagious disease that is
commonly spread by the sexual activity, including
oral and anal sex. The disease primarily starts in
the form of painless sore, particularly on genital,
rectum, or mouth. Disease can be transferred to
other person by close bodily contact. The pregnant
woman will transfer this disease to newborn.[1-6]
The bacteria can pass from mother to fetus. The
disease cannot spread using same objects such as
doorknobs and toilet seats. The disease is divided
into different phases on the basis of symptoms,
primary, secondary, latent, tertiary, neurosyphilis,
and congenital syphilis. The symptoms for primary
syphilis appear about 3 weeks of exposure. The
main symptom is the formation of painless sores.
These sores are called as chancres. Without
*Corresponding Author:
Urooj Fatima,
E-mail: uf60830@gmail.com
cure, the disease may lead to the next phase. The
secondary symptoms include muscle aches, fever,
sore throat, patchy hair loss, and swollen lymph
nodes. The latent syphilis can last for long time
sometimes for years. This phase occurs without
particular symptoms. The late or tertiary syphilis
occurs after 10–30 years of infection. This phase is
very fatal because it includes organ damage such
as damage to heart, blood vessels, liver, bones,
and joints. Neurosyphilis is a phase, in which
bacteria spread to nervous system. This results in
dementia, headache, abnormal gait, and weakness.
In congenital syphilis, infection can transfer from
mother to offspring. The symptoms in child are
fever, saddle nose, small blisters hands, and feet.
Penicillin is widely using for the treatment of
syphilis. Only single, long-term, intramuscular
injection of benzathine penicillin G can cure all
types of syphilis.
MATERIALS AND METHODS
Atotalof78subjectswereparticipatedinthisproject.
They all were 18–22 years old. They all asked some
questions about origin, causes, and transference
Qadir and Fatima: Realization of students about origin, signs, consequences of bacteria
IJMS/Jul-Sep-2019/Vol 3/Issue 3 13
of the syphilis disease.[7-10]
It is mostly unknown
disease. To create awareness of this disease, the
following questions were asked to the students.
Outlook of students toward the origin, signs,
and consequences of syphilis
It includes questionnaire to inspect consciousness
about etiology of syphilis, questionnaire to evaluate
perception about etiology of syphilis, questionnaire
to evaluate views about pervasiveness of syphilis,
questionnaire to evaluate views about transference
of syphilis, questionnaire to evaluate views about
hope for syphilis, realization about etiology of
syphilis: Outlook of postgraduate biology students
[Tables 1-6].
Table 2: Questionnaire to evaluate perception about
etiology of syphilis
Syphilis Males Females
Yes No Yes No
1.Disease is viral 1 14 3 60
2.Disease is bacterial 14 0 53 3
3.Disease is fungal 3 12 7 56
4.Genetic disease 3 12 60 3
5.Metabolic disease 2 13 16 47
Table 3: Questionnaire to evaluate views about
pervasiveness of syphilis
Ever suffered from syphilis Males Females
Yes No Yes No
1.You 1 14 6 57
2.Your family member 1 14 7 56
3.Your relative 1 14 10 53
4.Your neighbor 0 15 10 53
5.Your friend 1 14 6 57
Table 6: Realization about etiology of syphilis: Outlook
of postgraduate biology students
Questions Male (%) Female (%)
Yes No Yes No
1.Viral disease 1.28 18 3.84 96.1
2.Bacterial disease 17.9 0 67.9 3.84
3.Fungal disease 3.84 15.3 8.97 80.7
4.Genetic disease 15.3 3.84 76.4 3.84
5.Metabolic disease 2.56 16.66 20.5 60.25
Table 5: Questionnaire to evaluate views about hope for
syphilis
Syphilis may be treated by Males Females
Yes No Yes No
1.Medicines 15 0 48 15
2.Surgery 0 15 9 54
3.No treatment require 1 14 12 51
Table 4: Questionnaire to evaluate views about
transference of syphilis
Syphilis is transmitted by Males Females
Yes No Yes no
1.Contacts or blood transfusion 13 2 40 23
2.From parents to offspring 7 8 23 40
Table 1: Questionnaire to inspect consciousness about
etiology of syphilis
Question Yes No
1–
1. Syphilis is a viral disease
2. Syphilis is a bacterial disease
3. Syphilis is a fungal disease
4. Syphilis is a genetic disease
5. Syphilis is a metabolic disease
2–
6. Are you suffered from this
7. Are your family member suffered from this
8. Are your relative suffered from this
9. Are your neighbor suffered from this
10. Are your friend suffered from this
3–
11. Is it transferred by contact or blood transfusion
12. Is it transferred from mother to offspring
4–
13. Should it be cured by medicines
14. Should it be cured by surgery
15. Treatment is not required
Statistical analysis
This study was accomplished using the MS Word.
RESULTS AND DISCUSSION
Thefollowingquestionswereansweredby78students.
Mostly, they all were unaware of this disease and they
could not answer properly. Moreover, answers given
by those students were mostly incorrect. Syphilis is
basically caused by the sexual activity and oral and
anal sex. The main signs of syphilis are skin rash,
sores in mouth and anus, swollen glands, etc. It is
Qadir and Fatima: Realization of students about origin, signs, consequences of bacteria
IJMS/Jul-Sep-2019/Vol 3/Issue 3 14
transmitted by close bodily contact and also from
infected pregnant mother to offspring. The penicillin
is most widely used for the treatment of the syphilis.
It has been observed that Vaga et al. have studied
about the awareness of syphilis, they concluded that
syphilis is associated with a variety of social issues
and involves a wide spectrum of stakeholders in the
community; therefore, a collaborative, multifaceted
approach was thought to be essential and was used
in each city. As a result of the culturally tailored,
highly targeted, non-judgmental, and collaborative
efforts used by each city, high rates of campaign (and
thus syphilis) awareness were attained in each city.
Preliminary evaluation results suggest the campaigns
increased syphilis screening in some of the cities.
Syphilis is associated with a variety of social issues
and involves a wide spectrum of stakeholders in the
community; therefore, a collaborative, multifaceted
approach was thought to be essential and was used
in each city.
Question Male Female
Affected by from this disease
1.You 1.28% 17.94% 7.69% 60.25%
2.Your family member 1.28% 17.94% 8.97% 73.07%
3.Your relative 1.28% 17.94% 12.82% 67.94%
4.Your neighbor 0% 19.23% 12.82% 67.94%
5.Your friend 1.28% 17.94% 7.69% 73.03%
Syphilis transferred by
6.Contacts or blood
transfusion
16.66% 2.56% 51.28% 29.48%
7.From parents to offspring 8.97% 10.25% 29.48% 51.28%
Is it treated by
8.Medicines 19.23% 0% 61.53% 19.23%
9.Surgery 0% 19.23% 11.5% 69.23%
10.No need of treatment 1.28% 17.94% 15.38% 65.38%
CONCLUSION
I have searched out that this study has already been
done to aware of the people about causes, signs,
and remedy of this disease syphilis. Many projects
have been done about this. The main purpose of
all these projects was to aware of the people about
highly contagious and unknown disease.
REFERENCES
1. Brandt AM. Racism and research: The case of the
Tuskegee syphilis study. Hastings Cent Rep 1978;8:21‑9.
2. Berry CD, Hooton TM, Collier AC, Lukehart SA.
Neurologic relapse after benzathine penicillin therapy
for secondary syphilis in a patient with HIV infection.
N Engl J Med 1987;316:1587-9.
3. Qadir MI, Javid A. Awareness about crohn’s disease in
biotechnology students. Glob Adv Res J Med Med Sci
2018;7:62-4.
4. Qadir MI, Saleem A. Awareness about ischemic heart
disease in university biotechnology students. Glob Adv
Res J Med Med Sci 2018;7:59-61.
5. Qadir MI, Ishfaq S. Awareness about hypertension in
biology students. Int J Mod Pharm Res 2018;7:8-10.
6. Qadir MI, Mehwish M. Awareness about psoriasis
disease. Int J Mod Pharm Res 2018;7:17-8.
7. Qadir MI, Shahzad R. Awareness about obesity in
postgraduate students of biotechnology. Int J Mod Pharm
Res 2018;7:14-6.
8. Qadir MI, Rizvi M. Awareness about thalassemia in post
graduate students. MOJ Lymphol Phlebol 2018;2:14-6.
9. Qadir MI, Ghalia BA.Awareness survey about colorectal
cancer in students of M. Phil biotechnology at Bahauddin
Zakariya university, Multan, Pakistan. Nov Approaches
Cancer Study 2018;1:1-5.
10. Qadir MI, Saba G. Awareness about intestinal cancer
in university student. Nov Approaches Cancer Study
2018;1:1-3.

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Realization of students about origin, signs, consequences, and remedy of bacterial disease syphilis

  • 1. © 2019, IJMS. All Rights Reserved 12 Available Online at www.ijms.co.in Innovative Journal of Medical Sciences 2019; 3(3):12-14 ISSN 2581 – 4346 RESEARCH ARTICLE Realization of students about origin, signs, consequences, and remedy of bacterial disease syphilis Muhammad Imran Qadir, Urooj Fatima* Department of Biology, Institute of Molecular Biology and Biotechnology, Bahauddin Zakariya University, Multan, Pakistan Received on: 05 April 2019; Revised on: 10 May 2019; Accepted on: 10 June 2019 ABSTRACT Introduction: The questionnaire was produced to generate perception among students about causes, signs, and remedy of bacterial disease syphilis. Material and Method: About 78 subjects were participated in this study. They all are students of Bahauddin Zakariya University, Multan. I went to them and asked them the few questions about syphilis disease. Result: These questions were prepared to inform the students. The basic goal of this study was to create acknowledgment among students. Conclusion: From this study, I have concluded that most of people were unaware of this disease. They did not know about it. Keywords: Syphilis, Treponema, Congenital INTRODUCTION Syphilis is a bacterial disease that is caused by the bacteria Treponema pallidum. It can be treated in early stages. Without treatment, it can lead to fatal disorders such as neurological disorders and death. It is highly contagious disease that is commonly spread by the sexual activity, including oral and anal sex. The disease primarily starts in the form of painless sore, particularly on genital, rectum, or mouth. Disease can be transferred to other person by close bodily contact. The pregnant woman will transfer this disease to newborn.[1-6] The bacteria can pass from mother to fetus. The disease cannot spread using same objects such as doorknobs and toilet seats. The disease is divided into different phases on the basis of symptoms, primary, secondary, latent, tertiary, neurosyphilis, and congenital syphilis. The symptoms for primary syphilis appear about 3 weeks of exposure. The main symptom is the formation of painless sores. These sores are called as chancres. Without *Corresponding Author: Urooj Fatima, E-mail: uf60830@gmail.com cure, the disease may lead to the next phase. The secondary symptoms include muscle aches, fever, sore throat, patchy hair loss, and swollen lymph nodes. The latent syphilis can last for long time sometimes for years. This phase occurs without particular symptoms. The late or tertiary syphilis occurs after 10–30 years of infection. This phase is very fatal because it includes organ damage such as damage to heart, blood vessels, liver, bones, and joints. Neurosyphilis is a phase, in which bacteria spread to nervous system. This results in dementia, headache, abnormal gait, and weakness. In congenital syphilis, infection can transfer from mother to offspring. The symptoms in child are fever, saddle nose, small blisters hands, and feet. Penicillin is widely using for the treatment of syphilis. Only single, long-term, intramuscular injection of benzathine penicillin G can cure all types of syphilis. MATERIALS AND METHODS Atotalof78subjectswereparticipatedinthisproject. They all were 18–22 years old. They all asked some questions about origin, causes, and transference
  • 2. Qadir and Fatima: Realization of students about origin, signs, consequences of bacteria IJMS/Jul-Sep-2019/Vol 3/Issue 3 13 of the syphilis disease.[7-10] It is mostly unknown disease. To create awareness of this disease, the following questions were asked to the students. Outlook of students toward the origin, signs, and consequences of syphilis It includes questionnaire to inspect consciousness about etiology of syphilis, questionnaire to evaluate perception about etiology of syphilis, questionnaire to evaluate views about pervasiveness of syphilis, questionnaire to evaluate views about transference of syphilis, questionnaire to evaluate views about hope for syphilis, realization about etiology of syphilis: Outlook of postgraduate biology students [Tables 1-6]. Table 2: Questionnaire to evaluate perception about etiology of syphilis Syphilis Males Females Yes No Yes No 1.Disease is viral 1 14 3 60 2.Disease is bacterial 14 0 53 3 3.Disease is fungal 3 12 7 56 4.Genetic disease 3 12 60 3 5.Metabolic disease 2 13 16 47 Table 3: Questionnaire to evaluate views about pervasiveness of syphilis Ever suffered from syphilis Males Females Yes No Yes No 1.You 1 14 6 57 2.Your family member 1 14 7 56 3.Your relative 1 14 10 53 4.Your neighbor 0 15 10 53 5.Your friend 1 14 6 57 Table 6: Realization about etiology of syphilis: Outlook of postgraduate biology students Questions Male (%) Female (%) Yes No Yes No 1.Viral disease 1.28 18 3.84 96.1 2.Bacterial disease 17.9 0 67.9 3.84 3.Fungal disease 3.84 15.3 8.97 80.7 4.Genetic disease 15.3 3.84 76.4 3.84 5.Metabolic disease 2.56 16.66 20.5 60.25 Table 5: Questionnaire to evaluate views about hope for syphilis Syphilis may be treated by Males Females Yes No Yes No 1.Medicines 15 0 48 15 2.Surgery 0 15 9 54 3.No treatment require 1 14 12 51 Table 4: Questionnaire to evaluate views about transference of syphilis Syphilis is transmitted by Males Females Yes No Yes no 1.Contacts or blood transfusion 13 2 40 23 2.From parents to offspring 7 8 23 40 Table 1: Questionnaire to inspect consciousness about etiology of syphilis Question Yes No 1– 1. Syphilis is a viral disease 2. Syphilis is a bacterial disease 3. Syphilis is a fungal disease 4. Syphilis is a genetic disease 5. Syphilis is a metabolic disease 2– 6. Are you suffered from this 7. Are your family member suffered from this 8. Are your relative suffered from this 9. Are your neighbor suffered from this 10. Are your friend suffered from this 3– 11. Is it transferred by contact or blood transfusion 12. Is it transferred from mother to offspring 4– 13. Should it be cured by medicines 14. Should it be cured by surgery 15. Treatment is not required Statistical analysis This study was accomplished using the MS Word. RESULTS AND DISCUSSION Thefollowingquestionswereansweredby78students. Mostly, they all were unaware of this disease and they could not answer properly. Moreover, answers given by those students were mostly incorrect. Syphilis is basically caused by the sexual activity and oral and anal sex. The main signs of syphilis are skin rash, sores in mouth and anus, swollen glands, etc. It is
  • 3. Qadir and Fatima: Realization of students about origin, signs, consequences of bacteria IJMS/Jul-Sep-2019/Vol 3/Issue 3 14 transmitted by close bodily contact and also from infected pregnant mother to offspring. The penicillin is most widely used for the treatment of the syphilis. It has been observed that Vaga et al. have studied about the awareness of syphilis, they concluded that syphilis is associated with a variety of social issues and involves a wide spectrum of stakeholders in the community; therefore, a collaborative, multifaceted approach was thought to be essential and was used in each city. As a result of the culturally tailored, highly targeted, non-judgmental, and collaborative efforts used by each city, high rates of campaign (and thus syphilis) awareness were attained in each city. Preliminary evaluation results suggest the campaigns increased syphilis screening in some of the cities. Syphilis is associated with a variety of social issues and involves a wide spectrum of stakeholders in the community; therefore, a collaborative, multifaceted approach was thought to be essential and was used in each city. Question Male Female Affected by from this disease 1.You 1.28% 17.94% 7.69% 60.25% 2.Your family member 1.28% 17.94% 8.97% 73.07% 3.Your relative 1.28% 17.94% 12.82% 67.94% 4.Your neighbor 0% 19.23% 12.82% 67.94% 5.Your friend 1.28% 17.94% 7.69% 73.03% Syphilis transferred by 6.Contacts or blood transfusion 16.66% 2.56% 51.28% 29.48% 7.From parents to offspring 8.97% 10.25% 29.48% 51.28% Is it treated by 8.Medicines 19.23% 0% 61.53% 19.23% 9.Surgery 0% 19.23% 11.5% 69.23% 10.No need of treatment 1.28% 17.94% 15.38% 65.38% CONCLUSION I have searched out that this study has already been done to aware of the people about causes, signs, and remedy of this disease syphilis. Many projects have been done about this. The main purpose of all these projects was to aware of the people about highly contagious and unknown disease. REFERENCES 1. Brandt AM. Racism and research: The case of the Tuskegee syphilis study. Hastings Cent Rep 1978;8:21‑9. 2. Berry CD, Hooton TM, Collier AC, Lukehart SA. Neurologic relapse after benzathine penicillin therapy for secondary syphilis in a patient with HIV infection. N Engl J Med 1987;316:1587-9. 3. Qadir MI, Javid A. Awareness about crohn’s disease in biotechnology students. Glob Adv Res J Med Med Sci 2018;7:62-4. 4. Qadir MI, Saleem A. Awareness about ischemic heart disease in university biotechnology students. Glob Adv Res J Med Med Sci 2018;7:59-61. 5. Qadir MI, Ishfaq S. Awareness about hypertension in biology students. Int J Mod Pharm Res 2018;7:8-10. 6. Qadir MI, Mehwish M. Awareness about psoriasis disease. Int J Mod Pharm Res 2018;7:17-8. 7. Qadir MI, Shahzad R. Awareness about obesity in postgraduate students of biotechnology. Int J Mod Pharm Res 2018;7:14-6. 8. Qadir MI, Rizvi M. Awareness about thalassemia in post graduate students. MOJ Lymphol Phlebol 2018;2:14-6. 9. Qadir MI, Ghalia BA.Awareness survey about colorectal cancer in students of M. Phil biotechnology at Bahauddin Zakariya university, Multan, Pakistan. Nov Approaches Cancer Study 2018;1:1-5. 10. Qadir MI, Saba G. Awareness about intestinal cancer in university student. Nov Approaches Cancer Study 2018;1:1-3.