This document discusses radioactive iodine-125 seeds used for breast brachytherapy localization. I-125 is encapsulated in titanium and has a half-life of 60 days. The seeds allow temporary localization of non-palpable breast lesions and provide flexibility in scheduling surgery. Placement is performed by authorized users under an agreement with the state regulatory body and involves imaging, preparing the seed, precise needle-based delivery to the target site, and post-placement imaging to confirm location.
MRA can successfully conduct your next research study!Teresa Wright CCRP
Miami Research Associates continues to grow and offer enhanced R&D services. Contact us for more information on how we can help you execute your next early or late stage clinical trial.
MRA can successfully conduct your next research study; see how!Teresa Wright CCRP
Miami Research Associates continues to grow and offer enhanced R&D services. Contact Teresa Wright for more information on how we can help you execute your next early or late stage clinical trial.
Presentation from OIS@ASCRS 2016
Mike Judy, CEO
Video of Presentation:
https://www.youtube.com/watch?v=G5ZfnPKlBSY&list=PL1dmdBNnPTZJBhQxPOp0vdNg3s3wtN2yw&index=13
Dr. Eric Gingerich - Industry Perspective of the FDA Rule for Salmonella ente...John Blue
Industry Perspective of the FDA Rule for Salmonella enteritidis (SE) Monitoring - Dr. Eric Gingerich, Poultry Technical Services Specialist, Diamond V, from the 2012 Annual Conference of the National Institute for Animal Agriculture, March 26 - 29, Denver, CO, USA.
More presentations at: http://www.trufflemedia.com/agmedia/conference/2012-decreasing-resources-increasing-regulation-advance-animal-agriculture
What Is Assisted Hatching?
Assisted hatching is a laboratory technique designed to enhance implantation of embryos generated through in vitro fertilization (IVF). Most people are familiar with the failure of a cycle which is an unfortunate reality of assisted reproduction. Even when presumably high quality, fertile eggs are used, such as in egg donation with surrogates, nearly 40% to half of couples are still left disappointed each cycle. Since most couples are able to get eggs and have fertilization, then the question is where does the failure occur? The answer may be in the implantation phase.
In vitro fertilization (IVF) failure is a frustrating experience for individuals and couples, and it is often caused by an embryo's failure to implant in the uterus. For women who have failed IVF or have a poor prognosis for IVF, the fertility doctor may recommend a technique known as assisted hatching.Assisted hatching is a laboratory technique designed to enhance implantation of embryos generated through in vitro fertilization (IVF).
The correct application of the safety check steps in our routine theatre operations and procedures will greatly reduce surgically related mortality and morbidity.
MRA can successfully conduct your next research study!Teresa Wright CCRP
Miami Research Associates continues to grow and offer enhanced R&D services. Contact us for more information on how we can help you execute your next early or late stage clinical trial.
MRA can successfully conduct your next research study; see how!Teresa Wright CCRP
Miami Research Associates continues to grow and offer enhanced R&D services. Contact Teresa Wright for more information on how we can help you execute your next early or late stage clinical trial.
Presentation from OIS@ASCRS 2016
Mike Judy, CEO
Video of Presentation:
https://www.youtube.com/watch?v=G5ZfnPKlBSY&list=PL1dmdBNnPTZJBhQxPOp0vdNg3s3wtN2yw&index=13
Dr. Eric Gingerich - Industry Perspective of the FDA Rule for Salmonella ente...John Blue
Industry Perspective of the FDA Rule for Salmonella enteritidis (SE) Monitoring - Dr. Eric Gingerich, Poultry Technical Services Specialist, Diamond V, from the 2012 Annual Conference of the National Institute for Animal Agriculture, March 26 - 29, Denver, CO, USA.
More presentations at: http://www.trufflemedia.com/agmedia/conference/2012-decreasing-resources-increasing-regulation-advance-animal-agriculture
What Is Assisted Hatching?
Assisted hatching is a laboratory technique designed to enhance implantation of embryos generated through in vitro fertilization (IVF). Most people are familiar with the failure of a cycle which is an unfortunate reality of assisted reproduction. Even when presumably high quality, fertile eggs are used, such as in egg donation with surrogates, nearly 40% to half of couples are still left disappointed each cycle. Since most couples are able to get eggs and have fertilization, then the question is where does the failure occur? The answer may be in the implantation phase.
In vitro fertilization (IVF) failure is a frustrating experience for individuals and couples, and it is often caused by an embryo's failure to implant in the uterus. For women who have failed IVF or have a poor prognosis for IVF, the fertility doctor may recommend a technique known as assisted hatching.Assisted hatching is a laboratory technique designed to enhance implantation of embryos generated through in vitro fertilization (IVF).
The correct application of the safety check steps in our routine theatre operations and procedures will greatly reduce surgically related mortality and morbidity.
2. It is the temporary implant of low dose rate
brachytherapy seed to localize one or many
non-palpable lesion.
3. I-125 adsorbed onto silver, encased in titanium
Half-life of I-125 is 60 days
No contamination issues as long as not damaged or
casing breached.
No significant dose to those handling seeds if handled
properly
No dosimeters required
Studies have shown no increase in physician or
technologist exposure
6. Agreement State
Under the agreement of the United States
Nuclear Regulatory Commission
Radioactive material is regulated by the
Virginia Department of Health
7. Authorized Users
Regulatory training and experience
requirements
Approved by UVA Radiation Safety
Committee
Lead RadioSeed Techonologist
11. Needs
Preoperative blood work
Sx date scheduled
Written Directive
Patient Records/Consent
Form
Needs
Copy of Procedure
Survey Instrument
Emergency response
equipment/numbers
Decay chart
Seed needle
Local Anesthetic
12. Precautions
ALARA
Needle Stick
Losing seed
Not identifying pt has
seed
Survey Instrument
malfunction
Precautions
Never MRI
Can’t leave room until
seed location is
confirmed in breast
Lymphoscintigraphy
Security
13. Patient Consent
Patient identity is verified
Doors are locked
Patient is positioned under stereotactic paddle/US
Written Directive
14. Images taken
Determination of needle length and activity
determined
Technologist retrieves seed from locked cabinet
security maintained on remaining seeds
Seed is logged out of inventory
15.
16. Time out performed
Survey of needle with survey instrument done to
confirm seed is present
Needle is positioned
Seed is placed
17.
18. Confirmation that seed was placed successfully in
breast is done with survey instrument
Technologist will write “SEED” directly on patients
breast that contains seed. As well as number of
seeds placed
Patient given marker to take home to maintain this
marking
19.
20. Post placement images taken
Green armband is placed
Patient given mammogram images documenting
placement
Localization report completed
AU signs post procedural section of WD